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Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 1, 2002, Pages 9-12

Design, synthesis and pharmacological evaluation of novel pyrazolo[3,4-b]thieno[2,3-d]pyridine acid derivatives: A new class of anti-inflammatory and anti-platelet agents

(6) Cardoso, Carla R a De Brito, Fernanda C F a Da Silva, Kelli C M a De Miranda, Ana L P a Fraga, Carlos A M a Barreiro, Eliezer J a

a FEDERAL UNIVERSITY OF RIO DE JANEIRO (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ANTIINFLAMMATORY AGENT; ANTITHROMBOCYTIC AGENT; ARACHIDONIC ACID; COLLAGEN; GLUTARIC ACID DERIVATIVE; INDOMETACIN; LASSBIO 341; LEUKOTRIENE RECEPTOR BLOCKING AGENT; THROMBOXANE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

AIRWAY CONSTRICTION; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; GUINEA PIG; IC 50; NONHUMAN; PLEURISY; RAT; THROMBOCYTE AGGREGATION; TRACHEA;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DISEASE MODELS, ANIMAL; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; EDEMA; LEUKOTRIENE ANTAGONISTS; MEMBRANE PROTEINS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLEURISY; PYRAZOLES; PYRIDINES; RABBITS; RATS; RECEPTORS, LEUKOTRIENE; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES; THROMBOXANE-A SYNTHASE;

CAVIA PORCELLUS; SUS SCROFA;

EID: 0037033179 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(01)00651-5 Document Type: Article

Times cited : (20)

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