In vitro pharmacologic profile of YM158, a new dual antagonist for LTD4 and TXA2 receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 287, Issue 2, 1998, Pages 633-639

  Arakida, Yasuhito ^a   Suwa, Kiyomi ^a   Ohga, Keiko ^a   Yokota, Masaki ^a   Miyata, Keiji ^a   Yamada, Toshimitsu ^a   Honda, Kazuo ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 3 [(4 TERT BUTYL 2 THIAZOLYL)METHOXY] 5' [3 (4 CHLOROBENZENESULFONYL)PROPYL] 2' (1H TETRAZOL 5 YLMETHOXY)BENZANILIDE; 3 [(4 TERT BUTYLTHIAZOL 2 YL)METHOXY] 5' [3 (4 CHLOROBENEZENESULFONYL) PROPYL] 2' (1H TETRAZOL 5 YLMETHOXY)BENZANILIDE; ANTIASTHMATIC AGENT; CARBACHOL; LEUKOTRIENE D4; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MONTELUKAST; PRANLUKAST; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; ZAFIRLUKAST;

ANIMAL TISSUE; ARTICLE; ASTHMA; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; GUINEA PIG; ISOLATED ORGAN; MALE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; TRACHEA;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; CARBACHOL; DINOPROST; GUINEA PIGS; HUMANS; LEUKOTRIENE ANTAGONISTS; LEUKOTRIENE D4; MALE; MEMBRANE PROTEINS; MUSCLE CONTRACTION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PROSTAGLANDIN D2; RECEPTORS, LEUKOTRIENE; RECEPTORS, THROMBOXANE; TETRAZOLES; THIAZOLES; TRACHEA;

EID: 0032469938     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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