-
1
-
-
0033680583
-
P2 purinergic receptors: Modulation of cell function and therapeutic potential
-
Burnstock, G., and M. Williams. 2000. P2 purinergic receptors: modulation of cell function and therapeutic potential. J. Pharmacol Exp. Ther. 295: 862-869.
-
(2000)
J. Pharmacol Exp. Ther.
, vol.295
, pp. 862-869
-
-
Burnstock, G.1
Williams, M.2
-
2
-
-
0029665112
-
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
-
Surprenant, A., F. Rassendren, E. Kawashima, R. A. North, and G. Buell. 1996. The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 272: 735-738.
-
(1996)
Science
, vol.272
, pp. 735-738
-
-
Surprenant, A.1
Rassendren, F.2
Kawashima, E.3
North, R.A.4
Buell, G.5
-
3
-
-
0032515185
-
Cloning and functional characterisation of the mouse P2X7 receptor
-
Chessell, I. P., J. Simon, A. D. Hibell, A. D. Michel, E. A. Barnard, and P. P. Humphrey. 1998. Cloning and functional characterisation of the mouse P2X7 receptor. FEBS Lett. 439: 26-30.
-
(1998)
FEBS Lett.
, vol.439
, pp. 26-30
-
-
Chessell, I.P.1
Simon, J.2
Hibell, A.D.3
Michel, A.D.4
Barnard, E.A.5
Humphrey, P.P.6
-
4
-
-
0037424417
-
P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region
-
Smart, M. L., B. Gu, R. G. Panchal, J. Wiley, B. Cromer, D. A. Williams, and S. Petrou. 2003. P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region. J. Biol. Chem. 278: 8853-8860.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8853-8860
-
-
Smart, M.L.1
Gu, B.2
Panchal, R.G.3
Wiley, J.4
Cromer, B.5
Williams, D.A.6
Petrou, S.7
-
5
-
-
0035253835
-
Nucleotide receptors: An emerging family of regulatory molecules in blood cells
-
Di Virgilio, F., P. Chiozzi, D. Ferrari, S. Falzoni, J. M. Sanz, A. Morelli, M. Torboli, G. Bolognesi, and O. R. Baricordi. 2001. Nucleotide receptors: an emerging family of regulatory molecules in blood cells. Blood 97: 587-600.
-
(2001)
Blood
, vol.97
, pp. 587-600
-
-
Di Virgilio, F.1
Chiozzi, P.2
Ferrari, D.3
Falzoni, S.4
Sanz, J.M.5
Morelli, A.6
Torboli, M.7
Bolognesi, G.8
Baricordi, O.R.9
-
6
-
-
0031054641
-
Purinergic modulation of interleukin-1 β release from microglial cells stimulated with bacterial endotoxin
-
Ferrari, D., P. Chiozzi, S. Falzoni, S. Hanau, and F. Di Virgilio. 1997. Purinergic modulation of interleukin-1 β release from microglial cells stimulated with bacterial endotoxin. J. Exp. Med. 185: 579-582.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 579-582
-
-
Ferrari, D.1
Chiozzi, P.2
Falzoni, S.3
Hanau, S.4
Di Virgilio, F.5
-
7
-
-
0031201476
-
Extracellular ATP triggers IL-1 β release by activating the purinergic P2Z receptor of human macrophages
-
Ferrari, D., P. Chiozzi, S. Falzoni, M. Dal Susino, L. Melchiorri, O. R. Baricordi, and F. Di Virgilio. 1997. Extracellular ATP triggers IL-1 β release by activating the purinergic P2Z receptor of human macrophages. J. Immunol. 159: 1451-1458.
-
(1997)
J. Immunol.
, vol.159
, pp. 1451-1458
-
-
Ferrari, D.1
Chiozzi, P.2
Falzoni, S.3
Dal Susino, M.4
Melchiorri, L.5
Baricordi, O.R.6
Di Virgilio, F.7
-
8
-
-
0842322759
-
Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia
-
Suzuki, T., I, Hide, K. Ido, S. Kohsaka, K. Inoue, and Y. Nakata. 2004. Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia. J. Neurosci. 24: 1-7.
-
(2004)
J. Neurosci.
, vol.24
, pp. 1-7
-
-
Suzuki, T.1
Hide, I.2
Ido, K.3
Kohsaka, S.4
Inoue, K.5
Nakata, Y.6
-
9
-
-
13244249726
-
Bi-functional effects of ATP/P2 receptor activation on tumor necrosis factor-α release in lipopolysaccharide-stimulated astrocytes
-
Kucher, B. M., and J. T. Neary. 2005. Bi-functional effects of ATP/P2 receptor activation on tumor necrosis factor-α release in lipopolysaccharide-stimulated astrocytes. J Neurochem. 92: 525-535.
-
(2005)
J. Neurochem.
, vol.92
, pp. 525-535
-
-
Kucher, B.M.1
Neary, J.T.2
-
11
-
-
0037449706
-
lck, MAP kinases, and transcription factors AP-I and NF-κB
-
lck, MAP kinases, and transcription factors AP-I and NF-κB. J. Biol. Chem. 278: 1549-1560.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1549-1560
-
-
Budagian, V.1
Bulanova, E.2
Brovko, L.3
Orinska, Z.4
Fayad, R.5
Paus, R.6
Bulfone-Paus, S.7
-
12
-
-
0030757928
-
Spontaneous cell fusion in macrophage cultures expressing high levels of the P2Z/P2X7 receptor
-
Chiozzi, P., J. M. Sanz, D. Ferrari, S. Falzoni, A. Aleotti, G. N. Buell, G. Collo, and F. Di Virgilio. 1997. Spontaneous cell fusion in macrophage cultures expressing high levels of the P2Z/P2X7 receptor. J. Cell Biol. 138: 697-706.
-
(1997)
J. Cell Biol.
, vol.138
, pp. 697-706
-
-
Chiozzi, P.1
Sanz, J.M.2
Ferrari, D.3
Falzoni, S.4
Aleotti, A.5
Buell, G.N.6
Collo, G.7
Di Virgilio, F.8
-
13
-
-
0032711038
-
ATP receptors and giant cell formation
-
Di Virgilio, F., S. Falzoni, P. Chiozzi, J. M. Sanz, D. Ferrari, and G. N. Buell. 1999. ATP receptors and giant cell formation. J. Leukocyte Biol. 66: 723-726.
-
(1999)
J. Leukocyte Biol.
, vol.66
, pp. 723-726
-
-
Di Virgilio, F.1
Falzoni, S.2
Chiozzi, P.3
Sanz, J.M.4
Ferrari, D.5
Buell, G.N.6
-
14
-
-
0030840444
-
ATP-induced killing of mycobacteria by human macrophages is mediated by purinergic P2Z(P2X7) receptors
-
Lammas, D. A., C. Stober, C. J. Harvey, N. Kendrick, S. Panchalingam, and D. S. Kumararatne. 1997. ATP-induced killing of mycobacteria by human macrophages is mediated by purinergic P2Z(P2X7) receptors. Immunity 7: 433-444.
-
(1997)
Immunity
, vol.7
, pp. 433-444
-
-
Lammas, D.A.1
Stober, C.2
Harvey, C.J.3
Kendrick, N.4
Panchalingam, S.5
Kumararatne, D.S.6
-
15
-
-
0035016021
-
Modulation of P2Z/P2X(7) receptor activity in macrophages infected with Chlamydia psittaci
-
Coutinho-Silva, R., J. L. Perfettini, P. M. Persechini, A. Dautry-Varsat, and D. M. Ojcius. 2001. Modulation of P2Z/P2X(7) receptor activity in macrophages infected with Chlamydia psittaci. Am. J. Physiol 280: C81-C89.
-
(2001)
Am. J. Physiol
, vol.280
-
-
Coutinho-Silva, R.1
Perfettini, J.L.2
Persechini, P.M.3
Dautry-Varsat, A.4
Ojcius, D.M.5
-
16
-
-
0033957426
-
ATP-induced killing of virulent Mycobacterium tuberculosis within human macrophages requires phospholipase D
-
Kusner, D. J., and J. Adams, 2000. ATP-induced killing of virulent Mycobacterium tuberculosis within human macrophages requires phospholipase D. J. Immunol. 164: 379-388.
-
(2000)
J. Immunol.
, vol.164
, pp. 379-388
-
-
Kusner, D.J.1
Adams, J.2
-
17
-
-
0032538560
-
Purinergic receptor modulation of lipopolysaccharide signaling and inducible nitric oxide synthase expression in RAW 264.7 macrophages
-
Hu, Y., P. L. Fisette, L. C. Denlinger, A. G. Guadarrama, J. A. Sommer, R. A. Proctor, and P. J. Bertics. 1998. Purinergic receptor modulation of lipopolysaccharide signaling and inducible nitric oxide synthase expression in RAW 264.7 macrophages. J. Biol. Chem. 273: 27170-27175.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27170-27175
-
-
Hu, Y.1
Fisette, P.L.2
Denlinger, L.C.3
Guadarrama, A.G.4
Sommer, J.A.5
Proctor, R.A.6
Bertics, P.J.7
-
18
-
-
0141884377
-
P2X7 nucleotide receptor activation enhances IFN-γ-induced type 11 nitric oxide synthase activity in BV-2 microglial cells
-
Gendron, F. P., M. Chalimoniuk, J. Strosznajder, S. Shen, F. A. Gonzalez, G. A. Weisman, and G. Y. Sun. 2003. P2X7 nucleotide receptor activation enhances IFN-γ-induced type 11 nitric oxide synthase activity in BV-2 microglial cells. J. Neurochem. 87: 344-352.
-
(2003)
J. Neurochem.
, vol.87
, pp. 344-352
-
-
Gendron, F.P.1
Chalimoniuk, M.2
Strosznajder, J.3
Shen, S.4
Gonzalez, F.A.5
Weisman, G.A.6
Sun, G.Y.7
-
19
-
-
0032147124
-
Adenosine triphosphate-induced shedding of CD23 and L-selectin (CD62L) from lymphocytes is mediated by the same receptor but different metalloproteases
-
Gu, B., L. J. Bendall, and J. S. Wiley. 1998. Adenosine triphosphate-induced shedding of CD23 and L-selectin (CD62L) from lymphocytes is mediated by the same receptor but different metalloproteases. Blood 92: 946-951.
-
(1998)
Blood
, vol.92
, pp. 946-951
-
-
Gu, B.1
Bendall, L.J.2
Wiley, J.S.3
-
20
-
-
0037096207
-
Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response
-
Labasi, J. M., N. Petrushova, C. Donovan, S. McCurdy, P. Lira, M. M. Payette, W. Brissette, J. R. Wicks, L. Audoly, and C. A. Gabel. 2002. Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response. J. Immunol 168: 6436-6445.
-
(2002)
J. Immunol.
, vol.168
, pp. 6436-6445
-
-
Labasi, J.M.1
Petrushova, N.2
Donovan, C.3
McCurdy, S.4
Lira, P.5
Payette, M.M.6
Brissette, W.7
Wicks, J.R.8
Audoly, L.9
Gabel, C.A.10
-
21
-
-
0035808396
-
Altered cytokine production in mice lacking P2X(7) receptors
-
Solle, M., J. Labasi, D. G. Perregaux, E. Stam, N. Petrushova, B. H. Koller, R. J. Griffiths, and C. A. Gabel. 2001. Altered cytokine production in mice lacking P2X(7) receptors. J. Biol. Chem. 276: 125-132.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 125-132
-
-
Solle, M.1
Labasi, J.2
Perregaux, D.G.3
Stam, E.4
Petrushova, N.5
Koller, B.H.6
Griffiths, R.J.7
Gabel, C.A.8
-
22
-
-
20144375454
-
Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain
-
Chessell, I. P., J. P. Hatcher, C. Bountra, A. D. Michel, J. P. Hughes, P. Green, J. Egerton, M. Murfin, J. Richardson, W. L. Peck, C. B. Giahames, M. A. Casula, Y. Yiangou, R. Birch, P. Anand, and G. N. Buell. 2005. Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain. Pain 114: 386-396.
-
(2005)
Pain
, vol.114
, pp. 386-396
-
-
Chessell, I.P.1
Hatcher, J.P.2
Bountra, C.3
Michel, A.D.4
Hughes, J.P.5
Green, P.6
Egerton, J.7
Murfin, M.8
Richardson, J.9
Peck, W.L.10
Giahames, C.B.11
Casula, M.A.12
Yiangou, Y.13
Birch, R.14
Anand, P.15
Buell, G.N.16
-
23
-
-
0034282888
-
Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor
-
Humphreys, B. D., J. Rice, S. B. Kertesy, and G. R. Dubyak. 2000. Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor. J. Biol. Chem. 275: 26792-26798.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26792-26798
-
-
Humphreys, B.D.1
Rice, J.2
Kertesy, S.B.3
Dubyak, G.R.4
-
24
-
-
0036200917
-
Purinergic (P2X7) receptor activation of microglia induces cell death via an interleukin-1-independent mechanism
-
Brough, D., R. A. Le Feuvre, Y. Iwakura, and N. J. Rothwell. 2002. Purinergic (P2X7) receptor activation of microglia induces cell death via an interleukin-1-independent mechanism. Mol Cell. Neurosci. 19: 272-280.
-
(2002)
Mol Cell. Neurosci.
, vol.19
, pp. 272-280
-
-
Brough, D.1
Le Feuvre, R.A.2
Iwakura, Y.3
Rothwell, N.J.4
-
26
-
-
0034714006
-
Characteristics of P2X7 receptors from human B lymphocytes expressed in Xenopus oocytes
-
Klapperstuck, M., C. Buttner, T. Bohm, G. Schmalzing, and F. Markwardt. 2000. Characteristics of P2X7 receptors from human B lymphocytes expressed in Xenopus oocytes. Biochim. Biophys. Acta 1467: 444-456.
-
(2000)
Biochim. Biophys. Acta
, vol.1467
, pp. 444-456
-
-
Klapperstuck, M.1
Buttner, C.2
Bohm, T.3
Schmalzing, G.4
Markwardt, F.5
-
27
-
-
0032209361
-
Partial agonists and antagonists reveal a second permeability state of human lymphocyte P2Z/P2X7 channel
-
Wiley, J. S., C. E. Gargett, W. Zhang, M. B. Snook, and G. P. Jamieson. 1998. Partial agonists and antagonists reveal a second permeability state of human lymphocyte P2Z/P2X7 channel. Am. J. Physiol. 275: C1224-C1231.
-
(1998)
Am. J. Physiol.
, vol.275
-
-
Wiley, J.S.1
Gargett, C.E.2
Zhang, W.3
Snook, M.B.4
Jamieson, G.P.5
-
28
-
-
0142188258
-
NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor
-
Seman, M., S. Adriouch, F. Scheuplein, C. Krebs, D. Freese, G. Glowacki, P. Deterre, F. Haag, and F. Koch-Nolte. 2003. NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor. Immunity 19: 571-582.
-
(2003)
Immunity
, vol.19
, pp. 571-582
-
-
Seman, M.1
Adriouch, S.2
Scheuplein, F.3
Krebs, C.4
Freese, D.5
Glowacki, G.6
Deterre, P.7
Haag, F.8
Koch-Nolte, F.9
-
29
-
-
13544258083
-
P2X7 receptor-dependent and -independent T cell death is induced by nicotinamide adenine dinucleotide
-
Kawamuia, H., F. Aswad, M. Minagawa, K. Malone, H. Kaslow, F. Koch-Nolte, W. H. Schott, E. H. Leiter, and G. Dennert. 2005. P2X7 receptor-dependent and -independent T cell death is induced by nicotinamide adenine dinucleotide. J. Immunol. 174: 1971-1979.
-
(2005)
J. Immunol.
, vol.174
, pp. 1971-1979
-
-
Kawamuia, H.1
Aswad, F.2
Minagawa, M.3
Malone, K.4
Kaslow, H.5
Koch-Nolte, F.6
Schott, W.H.7
Leiter, E.H.8
Dennert, G.9
-
30
-
-
23844435586
-
+ regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: A role for P2X7 receptors
-
+ regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: a role for P2X7 receptors. J. Immunol. 175: 3075-3083.
-
(2005)
J. Immunol.
, vol.175
, pp. 3075-3083
-
-
Aswad, F.1
Kawamura, H.2
Dennert, G.3
-
31
-
-
0028221166
-
Animal models
-
Wekerle, H., K. Kojima, J. Lannes-Vieira, H. Lassmann, and C. Linington. 1994. Animal models. Ann. Neurol. 36(Suppl.): S47-S53.
-
(1994)
Ann. Neurol.
, vol.36
, Issue.SUPPL.
-
-
Wekerle, H.1
Kojima, K.2
Lannes-Vieira, J.3
Lassmann, H.4
Linington, C.5
-
32
-
-
0028227138
-
The Dale E. McFarlin memorial lecture: The immunology of the multiple sclerosis lesion
-
Raine, C. S. 1994. The Dale E. McFarlin memorial lecture: the immunology of the multiple sclerosis lesion. Ann. Neurol. 36(Suppl.): S61-S72.
-
(1994)
Ann. Neurol.
, vol.36
, Issue.SUPPL.
-
-
Raine, C.S.1
-
33
-
-
13244283212
-
1L-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish, C. L., Y. Chen, W. M. Blumenschein, J. Mattson, B. Basham, J. D. Sedgwick, T. McClanahan, R. A. Kastelein, and D. J. Cua. 2005. 1L-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201: 233-240.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
34
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park, H., Z. Li, X. O. Yang, S. H. Chang, R. Nurieva, Y. H. Wang, Y. Wang, L. Hood, Z. Zhu, Q. Tian, and C. Dong. 2005. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 6: 1133-1141.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
36
-
-
0023264201
-
Interleukin 1 and myclin basic protein synergistically augment adoptive transfer activity of lymphocytes mediating experimental autoimmune encephalomyelitis in Lewis rats
-
Mannie, M. D., C. A. Dinarello, and P. Y. Paterson. 1987. Interleukin 1 and myclin basic protein synergistically augment adoptive transfer activity of lymphocytes mediating experimental autoimmune encephalomyelitis in Lewis rats. J. Immunol. 138: 4229-4235.
-
(1987)
J. Immunol.
, vol.138
, pp. 4229-4235
-
-
Mannie, M.D.1
Dinarello, C.A.2
Paterson, P.Y.3
-
37
-
-
0033775139
-
TNFR1 signaling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease
-
Probert, L., H. P. Eugster, K. Akassoglou, J. Bauer, K. Frei, H. Lassmann, and A. Fontana. 2000. TNFR1 signaling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease. Brain 123: 2005-2019.
-
(2000)
Brain
, vol.123
, pp. 2005-2019
-
-
Probert, L.1
Eugster, H.P.2
Akassoglou, K.3
Bauer, J.4
Frei, K.5
Lassmann, H.6
Fontana, A.7
-
38
-
-
0036479134
-
Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production
-
Le Feuvre, R. A., D. Brough, Y. Iwakura, K. Takeda, and N. J. Rothwell. 2002. Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production. J. Biol. Chem. 277: 3210-3218.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3210-3218
-
-
Le Feuvre, R.A.1
Brough, D.2
Iwakura, Y.3
Takeda, K.4
Rothwell, N.J.5
-
39
-
-
0029901881
-
A pathogenic role for γδ T cells in relapsing-remitting experimental allergic encephalomyelitis in the SJL mouse
-
Rajan, A. J., Y. L. Gao, C. S. Raine, and C. F. Brosnan. 1996. A pathogenic role for γδ T cells in relapsing-remitting experimental allergic encephalomyelitis in the SJL mouse. J. Immunol. 157: 941-949.
-
(1996)
J. Immunol.
, vol.157
, pp. 941-949
-
-
Rajan, A.J.1
Gao, Y.L.2
Raine, C.S.3
Brosnan, C.F.4
-
40
-
-
14844344804
-
The cytokine IL-1β activates IFN response factor 3 in human fetal astrocytes in culture
-
Rivieccio, M. A., G. R. John, X. Song, H. S. Suh, Y. Zhao, S. C. Lee, and C. F. Brosnan. 2005. The cytokine IL-1β activates IFN response factor 3 in human fetal astrocytes in culture. J. Immunol. 174: 3719-3726.
-
(2005)
J. Immunol.
, vol.174
, pp. 3719-3726
-
-
Rivieccio, M.A.1
John, G.R.2
Song, X.3
Suh, H.S.4
Zhao, Y.5
Lee, S.C.6
Brosnan, C.F.7
-
41
-
-
0034965383
-
Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions
-
Liu, J. S., M. L. Zhao, C. F. Brosnan, and S. C. Lee. 2001. Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions. Am. J. Pathol. 158: 2057-2066.
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 2057-2066
-
-
Liu, J.S.1
Zhao, M.L.2
Brosnan, C.F.3
Lee, S.C.4
-
42
-
-
0037025282
-
Extracellular ATP and P2X7 receptors in neurodegeneration
-
Le Feuvre, R., D. Brough, and N. Rothwell. 2002. Extracellular ATP and P2X7 receptors in neurodegeneration. Eur. J. Pharmacol. 447: 261-269.
-
(2002)
Eur. J. Pharmacol.
, vol.447
, pp. 261-269
-
-
Le Feuvre, R.1
Brough, D.2
Rothwell, N.3
-
43
-
-
0031302405
-
Cell death during autoimmune demyelination: Effector but not target cells are eliminated by apoptosis
-
Bonetti, B., J. Pohl, Y. L. Gao, and C. S. Raine. 1997. Cell death during autoimmune demyelination: effector but not target cells are eliminated by apoptosis. J. Immunol. 159: 5733-5741.
-
(1997)
J. Immunol.
, vol.159
, pp. 5733-5741
-
-
Bonetti, B.1
Pohl, J.2
Gao, Y.L.3
Raine, C.S.4
-
44
-
-
0029065604
-
Antigen-specific down-regulation of myelin basic protein-reactive T cells during spontaneous recovery from experimental autoimmune encephalomyelitis: Further evidence of apoptotic deletion of autoreactive T cells in the central nervous system
-
Tabi, Z., P. A. McCombe, and M. P. Pender. 1995. Antigen-specific down-regulation of myelin basic protein-reactive T cells during spontaneous recovery from experimental autoimmune encephalomyelitis: further evidence of apoptotic deletion of autoreactive T cells in the central nervous system. Int. Immunol. 7: 967-973.
-
(1995)
Int. Immunol.
, vol.7
, pp. 967-973
-
-
Tabi, Z.1
McCombe, P.A.2
Pender, M.P.3
-
45
-
-
0034667786
-
Metalloprotease-mediated shedding of enzymatically active mouse ecto-ADP-ribosyltransferase ART2.2 upon T cell activation
-
Kahl, S., M. Nissen, R. Girisch, T. Duffy, E. H. Leiter, F. Haag, and F. Koch-Nolte. 2000. Metalloprotease-mediated shedding of enzymatically active mouse ecto-ADP-ribosyltransferase ART2.2 upon T cell activation. J. Immunol 165: 4463-4469.
-
(2000)
J. Immunol
, vol.165
, pp. 4463-4469
-
-
Kahl, S.1
Nissen, M.2
Girisch, R.3
Duffy, T.4
Leiter, E.H.5
Haag, F.6
Koch-Nolte, F.7
-
46
-
-
0034028453
-
The induction of EAE is only partially dependent on TNF receptor signaling but requires the IL-1 type I receptor
-
Schiffenbauer, J., W. J. Streit, E. Butfiloski, M. LaBow, C. Edwards III, and L. L. Moldawer. 2000. The induction of EAE is only partially dependent on TNF receptor signaling but requires the IL-1 type I receptor, Clin. Immunol. 95: 117-123.
-
(2000)
Clin. Immunol.
, vol.95
, pp. 117-123
-
-
Schiffenbauer, J.1
Streit, W.J.2
Butfiloski, E.3
Labow, M.4
Edwards III, C.5
Moldawer, L.L.6
-
47
-
-
0036694589
-
IL-6 in autoimmune disease and chronic inflammatory proliferative disease
-
Ishihara, K., and T. Hirano. 2002. IL-6 in autoimmune disease and chronic inflammatory proliferative disease. Cytokine Growth Factor Rev. 13: 357-368.
-
(2002)
Cytokine Growth Factor Rev.
, vol.13
, pp. 357-368
-
-
Ishihara, K.1
Hirano, T.2
-
48
-
-
0036130574
-
Cytokines and chemokines as mediators of protection and injury in the central nervous system assessed in transgenic mice
-
Wang, J., V. C. Asensio, and I. L. Campbell. 2002. Cytokines and chemokines as mediators of protection and injury in the central nervous system assessed in transgenic mice. Curr. Top. Microbiol. Immunol. 265: 23-48.
-
(2002)
Curr. Top. Microbiol. Immunol.
, vol.265
, pp. 23-48
-
-
Wang, J.1
Asensio, V.C.2
Campbell, I.L.3
-
49
-
-
0035883161
-
Interleukin-1β promotes repair of the CNS
-
Mason, J. L., K. Suzuki, D. D. Chaplin, and G. K. Matsushima. 2001. Interleukin-1β promotes repair of the CNS. J. Neurosci. 21: 7046-7052.
-
(2001)
J. Neurosci.
, vol.21
, pp. 7046-7052
-
-
Mason, J.L.1
Suzuki, K.2
Chaplin, D.D.3
Matsushima, G.K.4
-
50
-
-
0038392877
-
Astrocyte-targeted expression of IL-6 protects the CNS against a focal brain injury
-
Penkowa, M., M. Giralt, N. Lago, J. Camats, J. Carrasco, J. Hernandez, A. Molinero, I. L. Campbell, and J. Hidalgo. 2003. Astrocyte-targeted expression of IL-6 protects the CNS against a focal brain injury. Exp. Neurol. 181: 130-148.
-
(2003)
Exp. Neurol.
, vol.181
, pp. 130-148
-
-
Penkowa, M.1
Giralt, M.2
Lago, N.3
Camats, J.4
Carrasco, J.5
Hernandez, J.6
Molinero, A.7
Campbell, I.L.8
Hidalgo, J.9
-
51
-
-
0035970757
-
Interleukin-6 promotes post-traumatic healing in the central nervous system
-
Swartz, K. R., F. Liu, D. Sewell, T. Schochet, I. Campbell, M, Sandor, and Z. Fabry. 2001. Interleukin-6 promotes post-traumatic healing in the central nervous system. Brain Res. 896: 86-95.
-
(2001)
Brain Res.
, vol.896
, pp. 86-95
-
-
Swartz, K.R.1
Liu, F.2
Sewell, D.3
Schochet, T.4
Campbell, I.5
Sandor, M.6
Fabry, Z.7
-
52
-
-
20444394379
-
Mechanisms of axonal degeneration in EAE: Lessons from CNTF and MHC I knockout mice
-
Linker, R. A., M. Sendtner, and R. Gold. 2005. Mechanisms of axonal degeneration in EAE: lessons from CNTF and MHC I knockout mice. J. Neurol. Sci. 233: 167-172.
-
(2005)
J. Neurol. Sci.
, vol.233
, pp. 167-172
-
-
Linker, R.A.1
Sendtner, M.2
Gold, R.3
-
53
-
-
0033954469
-
Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis
-
Suvannavejh, G. C., M. C. Dal Canto, L. A. Matis, and S. D. Miller. 2000. Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis. J. Clin. Invest. 105: 223-231.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 223-231
-
-
Suvannavejh, G.C.1
Dal Canto, M.C.2
Matis, L.A.3
Miller, S.D.4
-
54
-
-
0033583427
-
Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis
-
Sabelko-Downes, K. A., A. H. Cross, and J. H. Russell. 1999. Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis. J. Exp. Med. 189: 1195-1205.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1195-1205
-
-
Sabelko-Downes, K.A.1
Cross, A.H.2
Russell, J.H.3
-
55
-
-
0034237154
-
Coexpression of Fas/FasL and Bax on brain and infiltrating T cells in the central nervous system is closely associated with apoptotic cell death during autoimmune encephalomyelitis
-
Kohji, T., and Y. Matsumoto. 2000. Coexpression of Fas/FasL and Bax on brain and infiltrating T cells in the central nervous system is closely associated with apoptotic cell death during autoimmune encephalomyelitis. J. Neuroimmunol. 106: 165-171.
-
(2000)
J. Neuroimmunol.
, vol.106
, pp. 165-171
-
-
Kohji, T.1
Matsumoto, Y.2
-
56
-
-
0037311027
-
Regulatory role of p53 in experimental autoimmune encephalomyelitis
-
Okuda, Y., M. Okuda, and C. C. Bernard. 2003. Regulatory role of p53 in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 135: 29-37.
-
(2003)
J. Neuroimmunol.
, vol.135
, pp. 29-37
-
-
Okuda, Y.1
Okuda, M.2
Bernard, C.C.3
-
57
-
-
0033571331
-
IFN-γ is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: A possible role for nitric oxide
-
Willenborg, D. O., S. A. Fordham, M. A. Staykova, I. A. Ramshaw, and W. B. Cowden. 1999. IFN-γ is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: a possible role for nitric oxide. J. Immunol. 163: 5278-5286.
-
(1999)
J. Immunol.
, vol.163
, pp. 5278-5286
-
-
Willenborg, D.O.1
Fordham, S.A.2
Staykova, M.A.3
Ramshaw, I.A.4
Cowden, W.B.5
-
58
-
-
0032146845
-
Nitric oxide is a potential down-regulating molecule in autoimmune disease: Inhibition of nitric oxide production renders PVG rats highly susceptible to EAE
-
Cowden, W. B., F. A. Cullen, M. A. Staykova, and D. O. Willenborg. 1998. Nitric oxide is a potential down-regulating molecule in autoimmune disease: inhibition of nitric oxide production renders PVG rats highly susceptible to EAE. J. Neuroimmunol. 88: 1-8.
-
(1998)
J. Neuroimmunol.
, vol.88
, pp. 1-8
-
-
Cowden, W.B.1
Cullen, F.A.2
Staykova, M.A.3
Willenborg, D.O.4
-
59
-
-
0033400628
-
Our shifting understanding of the role of nitric oxide in autoimmune encephalomyelitis: A review
-
Willenborg, D. O., M. A. Staykova, and W. B. Cowden. 1999. Our shifting understanding of the role of nitric oxide in autoimmune encephalomyelitis: a review. J. Neuroimmunol. 100: 21-35.
-
(1999)
J. Neuroimmunol.
, vol.100
, pp. 21-35
-
-
Willenborg, D.O.1
Staykova, M.A.2
Cowden, W.B.3
-
60
-
-
0037108511
-
Cutting edge: A natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor
-
Adriouch, S., C. Dos, V. Welge, M. Seman, F. Koch-Nolte, and F. Haag. 2002. Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor. J. Immunol. 169: 4108-4112.
-
(2002)
J. Immunol.
, vol.169
, pp. 4108-4112
-
-
Adriouch, S.1
Dos, C.2
Welge, V.3
Seman, M.4
Koch-Nolte, F.5
Haag, F.6
-
61
-
-
2342423633
-
The Pro-451 to Leu polymorphism within the C-terminal tail of P2X7 receptor impairs cell death but not phospholipase D activation in murine thymocytes
-
Le Stunff, H., R. Auger, J. Kanellopoulos, and M. N. Raymond. 2004. The Pro-451 to Leu polymorphism within the C-terminal tail of P2X7 receptor impairs cell death but not phospholipase D activation in murine thymocytes. J. Biol. Chem. 279: 16918-16926.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16918-16926
-
-
Le Stunff, H.1
Auger, R.2
Kanellopoulos, J.3
Raymond, M.N.4
-
62
-
-
0031921573
-
Nongenomic Inhibition of human P2X7 purinoceptor by 17β-oestradiol
-
Cario-Toumaniantz, C., G. Loirand, L. Ferner, and P. Pacaud. 1998. Nongenomic Inhibition of human P2X7 purinoceptor by 17β-oestradiol. J. Physiol. 508: 659-666.
-
(1998)
J. Physiol.
, vol.508
, pp. 659-666
-
-
Cario-Toumaniantz, C.1
Loirand, G.2
Ferner, L.3
Pacaud, P.4
-
63
-
-
9444228340
-
Antiapoptotic effects .of estrogen in normal and cancer human cervical epithelial cells
-
Wang, Q., X. Li, L. Wang, Y. H. Feng, R. Zeng, and G. Gorodeski. 2004. Antiapoptotic effects .of estrogen in normal and cancer human cervical epithelial cells. Endocrinology 145: 5568-5579.
-
(2004)
Endocrinology
, vol.145
, pp. 5568-5579
-
-
Wang, Q.1
Li, X.2
Wang, L.3
Feng, Y.H.4
Zeng, R.5
Gorodeski, G.6
-
64
-
-
0037634326
-
Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption
-
Ke, H. Z., H. Qi, A. F. Weidema, Q. Zhang, N. Panupinthu, D. T. Crawford, W. A. Grasser, V. M. Paralkar, M. Li, L. P. Audoly, C. A. Gabel, W. S. Jee, S. J. Dixon, S. M. Sims, and D. D. Thompson. 2003. Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption. Mol Endocrinol. 17: 1356-1367.
-
(2003)
Mol Endocrinol.
, vol.17
, pp. 1356-1367
-
-
Ke, H.Z.1
Qi, H.2
Weidema, A.F.3
Zhang, Q.4
Panupinthu, N.5
Crawford, D.T.6
Grasser, W.A.7
Paralkar, V.M.8
Li, M.9
Audoly, L.P.10
Gabel, C.A.11
Jee, W.S.12
Dixon, S.J.13
Sims, S.M.14
Thompson, D.D.15
-
65
-
-
0036533208
-
Gender does not influence the susceptibility of C57BL/6 mice to develop chronic experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein
-
Okuda, Y., M. Okuda, and C. C. Bernard. 2002. Gender does not influence the susceptibility of C57BL/6 mice to develop chronic experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein. Immunol. Lett. 81: 25-29.
-
(2002)
Immunol. Lett.
, vol.81
, pp. 25-29
-
-
Okuda, Y.1
Okuda, M.2
Bernard, C.C.3
-
66
-
-
1842737784
-
Sex differences in experimental autoimmune encephalomyelitis in multiple murine strains
-
Papenfuss, T. L., C. J. Rogers, I. Gienapp, M. Yurrita, M. McClain, N. Damico, J. Valo, F. Song, and C. C. Whitacre. 2004. Sex differences in experimental autoimmune encephalomyelitis in multiple murine strains. J. Neuroimmunol. 150: 59-69.
-
(2004)
J. Neuroimmunol.
, vol.150
, pp. 59-69
-
-
Papenfuss, T.L.1
Rogers, C.J.2
Gienapp, I.3
Yurrita, M.4
McClain, M.5
Damico, N.6
Valo, J.7
Song, F.8
Whitacre, C.C.9
-
67
-
-
0037384725
-
C57BLack/BOX? The importance of exact mouse strain nomenclature
-
Wotjak, C. T. 2003. C57BLack/BOX? The importance of exact mouse strain nomenclature. Trends Genet. 19: 183-184.
-
(2003)
Trends Genet.
, vol.19
, pp. 183-184
-
-
Wotjak, C.T.1
-
68
-
-
0035815630
-
A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor
-
Gu, B. J., W. Zhang, R. A. Worthington, R. Sluyter, P. Dao-Ung, S. Petrou, J. A. Barden, and J. S. Wiley. 2001. A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor. J. Biol. Chem. 276: 11135-11142.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11135-11142
-
-
Gu, B.J.1
Zhang, W.2
Worthington, R.A.3
Sluyter, R.4
Dao-Ung, P.5
Petrou, S.6
Barden, J.A.7
Wiley, J.S.8
-
69
-
-
0037931836
-
An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor
-
Wiley, J. S., L. P. Dao-Ung, C. Li, A. N. Shemon, B. J. Gu, M. L. Smart, S. J. Fuller, J. A. Barden, S. Petrou, and R. Sluyter. 2003. An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor. J. Biol. Chem. 278: 17108-17113.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17108-17113
-
-
Wiley, J.S.1
Dao-Ung, L.P.2
Li, C.3
Shemon, A.N.4
Gu, B.J.5
Smart, M.L.6
Fuller, S.J.7
Barden, J.A.8
Petrou, S.9
Sluyter, R.10
-
70
-
-
2342431309
-
A novel assay to detect nucleotide receptor P2X7 genetic polymorphisms influencing numerous innate immune functions
-
Denlinger, L. C., K. Schell, G. Angelini, D. Green, A. Guadarrama, U. Prabhu, D. B. Coursin, K. Hogan, and P. J. Bertics. 2004. A novel assay to detect nucleotide receptor P2X7 genetic polymorphisms influencing numerous innate immune functions. J Endotoxin Res. 10: 137-142.
-
(2004)
J Endotoxin Res.
, vol.10
, pp. 137-142
-
-
Denlinger, L.C.1
Schell, K.2
Angelini, G.3
Green, D.4
Guadarrama, A.5
Prabhu, U.6
Coursin, D.B.7
Hogan, K.8
Bertics, P.J.9
-
71
-
-
15444364434
-
Detection of human P2X7 nucleotide receptor polymorphisms by a novel monocyte pore assay predictive of alterations in lipopolysaccharide-induced cytokine production
-
Denlinger, L. C., G. Angelini, K. Schell, D. N. Green, A. G. Guadarrama, U. Prabhu, D. B. Coursin, P. J. Bertics, and K. Hogan. 2005. Detection of human P2X7 nucleotide receptor polymorphisms by a novel monocyte pore assay predictive of alterations in lipopolysaccharide-induced cytokine production. J. Immunol. 174: 4424-4431.
-
(2005)
J. Immunol.
, vol.174
, pp. 4424-4431
-
-
Denlinger, L.C.1
Angelini, G.2
Schell, K.3
Green, D.N.4
Guadarrama, A.G.5
Prabhu, U.6
Coursin, D.B.7
Bertics, P.J.8
Hogan, K.9
-
72
-
-
0037196958
-
A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: A molecular study
-
Wiley, J. S., L. P. Dao-Ung, B. J. Gu, R. Sluyter, A. N. Shemon, C. Li, J. Taper, J. Gallo, and A. Manoharan. 2002. A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study. Lancet 359: 1114-1119.
-
(2002)
Lancet
, vol.359
, pp. 1114-1119
-
-
Wiley, J.S.1
Dao-Ung, L.P.2
Gu, B.J.3
Sluyter, R.4
Shemon, A.N.5
Li, C.6
Taper, J.7
Gallo, J.8
Manoharan, A.9
-
73
-
-
3042636437
-
Association of the 1513C polymorphism in the P2X7 gene with familial forms of chronic lymphocytic leukaemia
-
Dao-Ung, L. P., S. J. Fuller, R. Sluyter, K. K. SkarRatt, U. Thunberg, G. Tobin, K. Byth, M. Ban, R. Rosenquist, G. J. Stewart, and J. S. Wiley. 2004. Association of the 1513C polymorphism in the P2X7 gene with familial forms of chronic lymphocytic leukaemia. Br. J. Haematol. 125: 815-817.
-
(2004)
Br. J. Haematol.
, vol.125
, pp. 815-817
-
-
Dao-Ung, L.P.1
Fuller, S.J.2
Sluyter, R.3
Skarratt, K.K.4
Thunberg, U.5
Tobin, G.6
Byth, K.7
Ban, M.8
Rosenquist, R.9
Stewart, G.J.10
Wiley, J.S.11
-
74
-
-
0037079306
-
Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia
-
Thunberg, U., G. Tobin, A. Johnson, O. Soderberg, L. Padyukov, M. Hultdin, L. Klareskog, G. Enblad, C. Sundstrom, G. Roos, and R. Rosenquist. 2002. Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia. Lancet 360: 1935-1939.
-
(2002)
Lancet
, vol.360
, pp. 1935-1939
-
-
Thunberg, U.1
Tobin, G.2
Johnson, A.3
Soderberg, O.4
Padyukov, L.5
Hultdin, M.6
Klareskog, L.7
Enblad, G.8
Sundstrom, C.9
Roos, G.10
Rosenquist, R.11
-
75
-
-
0037079543
-
P2X7 receptor expression in evolutive and indolent forms of chronic B lymphocytic leukemia
-
Adinolfi, E., L. Melchiorri, S. Falzoni, P. Chiozzi, A. Morelli, A. Tieghi, A. Cuneo, G. Castoldi, F. Di Virgilio, and O. R. Baricordi. 2002. P2X7 receptor expression in evolutive and indolent forms of chronic B lymphocytic leukemia. Blood 99: 706-708.
-
(2002)
Blood
, vol.99
, pp. 706-708
-
-
Adinolfi, E.1
Melchiorri, L.2
Falzoni, S.3
Chiozzi, P.4
Morelli, A.5
Tieghi, A.6
Cuneo, A.7
Castoldi, G.8
Di Virgilio, F.9
Baricordi, O.R.10
-
76
-
-
0037079312
-
The P2X7 receptor of CLL lymphocytes-a molecule with a split personality
-
Di Virgilio, F., and J. S. Wiley. 2002. The P2X7 receptor of CLL lymphocytes-a molecule with a split personality. Lancet 360: 1898-1899.
-
(2002)
Lancet
, vol.360
, pp. 1898-1899
-
-
Di Virgilio, F.1
Wiley, J.S.2
|