-
2
-
-
0032525964
-
LIN-12/Notch signaling: Lessons from worms and flies
-
Greenwald I. LIN-12/Notch signaling: lessons from worms and flies. Genes Dev. 12:1998;1751-1762
-
(1998)
Genes Dev.
, vol.12
, pp. 1751-1762
-
-
Greenwald, I.1
-
3
-
-
0025856717
-
TAN-1, the human homolog of the Drosophila notch gene is broken by chromosomal translocations in T lymphoblastic neoplasms
-
Ellisen L.W., Bird J., West D.C., Soreng A.L., Reynolds T.C., Smith S.D., et al. TAN-1, the human homolog of the Drosophila notch gene is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell. 66:1991;649-661
-
(1991)
Cell
, vol.66
, pp. 649-661
-
-
Ellisen, L.W.1
Bird, J.2
West, D.C.3
Soreng, A.L.4
Reynolds, T.C.5
Smith, S.D.6
-
4
-
-
0023856341
-
Clinical and biological characterization of T cell neoplasias with rearrangements of chromosome 7 band q34
-
Smith S.D., Morgan R., Gemmill R., Amylon M.D., Lind M.P., Linker C., et al. Clinical and biological characterization of T cell neoplasias with rearrangements of chromosome 7 band q34. Blood. 71:1988;395-402
-
(1988)
Blood
, vol.71
, pp. 395-402
-
-
Smith, S.D.1
Morgan, R.2
Gemmill, R.3
Amylon, M.D.4
Lind, M.P.5
Linker, C.6
-
5
-
-
0033397647
-
Cytogenetics and molecular genetics of childhood leukemia
-
Ma S.K., Wan T.S., Chan L.C. Cytogenetics and molecular genetics of childhood leukemia. Hematol. Oncol. 17:1999;91-105
-
(1999)
Hematol. Oncol.
, vol.17
, pp. 91-105
-
-
Ma, S.K.1
Wan, T.S.2
Chan, L.C.3
-
6
-
-
0037441471
-
Differential regulation of Notch signal transduction in leukaemia and lymphoma cells in culture
-
Chiaramonte R., Calzavara E., Balordi F., Sabbadini M., Capello D., Gaidano G., et al. Differential regulation of Notch signal transduction in leukaemia and lymphoma cells in culture. J. Cell Biochem. 88:2003;569-577
-
(2003)
J. Cell Biochem.
, vol.88
, pp. 569-577
-
-
Chiaramonte, R.1
Calzavara, E.2
Balordi, F.3
Sabbadini, M.4
Capello, D.5
Gaidano, G.6
-
7
-
-
0033637705
-
A notch-independent activity of suppressor of hairless is required for normal mechanoreceptor physiology
-
Barolo S., Walker R.G., Polyanovsky A.D., Freschi G., Keil T., Posakony J.W. A notch-independent activity of suppressor of hairless is required for normal mechanoreceptor physiology. Cell. 103:2000;957-969
-
(2000)
Cell
, vol.103
, pp. 957-969
-
-
Barolo, S.1
Walker, R.G.2
Polyanovsky, A.D.3
Freschi, G.4
Keil, T.5
Posakony, J.W.6
-
8
-
-
0036566557
-
Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma
-
Jundt F., Anagnostopoulos I., Forster R., Mathas S., Stein H., Dorken B. Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma. Blood. 99:2002;3398-3403
-
(2002)
Blood
, vol.99
, pp. 3398-3403
-
-
Jundt, F.1
Anagnostopoulos, I.2
Forster, R.3
Mathas, S.4
Stein, H.5
Dorken, B.6
-
9
-
-
0037133497
-
Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis
-
Bellavia D., Campese A.F., Checquolo S., Balestri A., Biondi A., Cazzaniga G., et al. Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis. Proc. Natl. Acad. Sci. U.S.A. 99:2002;3788-3793
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 3788-3793
-
-
Bellavia, D.1
Campese, A.F.2
Checquolo, S.3
Balestri, A.4
Biondi, A.5
Cazzaniga, G.6
-
10
-
-
0142126194
-
Gene expression profiling in T-cell acute lymphoblastic leukemia
-
Ferrando A.A., Look A.T. Gene expression profiling in T-cell acute lymphoblastic leukemia. Semin. Hematol. 40:2003;274-280
-
(2003)
Semin. Hematol.
, vol.40
, pp. 274-280
-
-
Ferrando, A.A.1
Look, A.T.2
-
13
-
-
0029942842
-
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
-
Pear W.S., Aster J.C., Scott M.L., Hasserjian R.P., Soffer B., Sklar J., et al. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J. Exp. Med. 183:1996;2283-2291
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2283-2291
-
-
Pear, W.S.1
Aster, J.C.2
Scott, M.L.3
Hasserjian, R.P.4
Soffer, B.5
Sklar, J.6
-
14
-
-
20244389684
-
Notch1 expression in early lymphopoiesis influences B versus T lineage determination
-
Pui J.C., Allman D., Xu L., DeRocco S., Karnell F.G., Bakkour S., et al. Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity. 11:1999;299-308
-
(1999)
Immunity
, vol.11
, pp. 299-308
-
-
Pui, J.C.1
Allman, D.2
Xu, L.3
Derocco, S.4
Karnell, F.G.5
Bakkour, S.6
-
15
-
-
0035477668
-
Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus
-
Wilson A., MacDonald H.R., Radtke F. Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus. J. Exp. Med. 194:2001;1003-1012
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1003-1012
-
-
Wilson, A.1
MacDonald, H.R.2
Radtke, F.3
-
16
-
-
0035988246
-
Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision
-
Han H., Tanigaki K., Yamamoto N., Kuroda K., Yoshimoto M., Nakahata T., et al. Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision. Int. Immunol. 14:2002;637-645
-
(2002)
Int. Immunol.
, vol.14
, pp. 637-645
-
-
Han, H.1
Tanigaki, K.2
Yamamoto, N.3
Kuroda, K.4
Yoshimoto, M.5
Nakahata, T.6
-
17
-
-
0038742790
-
Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development
-
Saito T., Chiba S., Ichikawa M., Kunisato A., Asai T., Shimizu K., et al. Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development. Immunity. 18:2003;675-685
-
(2003)
Immunity
, vol.18
, pp. 675-685
-
-
Saito, T.1
Chiba, S.2
Ichikawa, M.3
Kunisato, A.4
Asai, T.5
Shimizu, K.6
-
18
-
-
0345689442
-
Characterization of Notch3-deficient mice: Normal embryonic development and absence of genetic interactions with a Notch1 mutation
-
Krebs L.T., Xue Y., Norton C.R., Sundberg J.P., Beatus P., Lendahl U., et al. Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation. Genesis. 37:2003;139-143
-
(2003)
Genesis
, vol.37
, pp. 139-143
-
-
Krebs, L.T.1
Xue, Y.2
Norton, C.R.3
Sundberg, J.P.4
Beatus, P.5
Lendahl, U.6
-
19
-
-
0034212710
-
Notch signaling is essential for vascular morphogenesis in mice
-
Krebs L.T., Xue Y., Norton C.R., Shutter J.R., Maguire M., Sundberg J.P., et al. Notch signaling is essential for vascular morphogenesis in mice. Genes Dev. 14:2000;1343-1352
-
(2000)
Genes Dev.
, vol.14
, pp. 1343-1352
-
-
Krebs, L.T.1
Xue, Y.2
Norton, C.R.3
Shutter, J.R.4
Maguire, M.5
Sundberg, J.P.6
-
20
-
-
0029773904
-
Modulated expression of notch1 during thymocyte development
-
Hasserjian R.P., Aster J.C., Davi F., Weinberg D.S., Sklar J. Modulated expression of notch1 during thymocyte development. Blood. 88:1996;970-976
-
(1996)
Blood
, vol.88
, pp. 970-976
-
-
Hasserjian, R.P.1
Aster, J.C.2
Davi, F.3
Weinberg, D.S.4
Sklar, J.5
-
21
-
-
0036467663
-
Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway
-
Reizis B., Leder P. Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway. Genes Dev. 16:2002;295-300
-
(2002)
Genes Dev.
, vol.16
, pp. 295-300
-
-
Reizis, B.1
Leder, P.2
-
22
-
-
0036070308
-
Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta lineage thymocytes
-
Wolfer A., Wilson A., Nemir M., MacDonald H.R., Radtke F. Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta lineage thymocytes. Immunity. 16:2002;869-879
-
(2002)
Immunity
, vol.16
, pp. 869-879
-
-
Wolfer, A.1
Wilson, A.2
Nemir, M.3
MacDonald, H.R.4
Radtke, F.5
-
23
-
-
0033681301
-
Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes
-
Deftos M.L., Huang E., Ojala E.W., Forbush K.A., Bevan M.J. Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes. Immunity. 13:2000;73-84
-
(2000)
Immunity
, vol.13
, pp. 73-84
-
-
Deftos, M.L.1
Huang, E.2
Ojala, E.W.3
Forbush, K.A.4
Bevan, M.J.5
-
24
-
-
0347951391
-
Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell-dependent mechanism
-
Wong K.K., Carpenter M.J., Young L.L., Walker S.J., McKenzie G., Rust A.J., et al. Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell-dependent mechanism. J. Clin. Invest. 112:2003;1741-1750
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1741-1750
-
-
Wong, K.K.1
Carpenter, M.J.2
Young, L.L.3
Walker, S.J.4
McKenzie, G.5
Rust, A.J.6
-
25
-
-
0242493801
-
Over expression of the Notch ligand, Jagged-1 induces alloantigen-specific human regulatory T cells
-
Yvon ES, Vigouroux S, Rousseau RF, Biagi E, Amrolia P, Dotti G, et al. Over expression of the Notch ligand, Jagged-1 induces alloantigen-specific human regulatory T cells. Blood 2003;1028:3815-21.
-
(2003)
Blood
, vol.1028
, pp. 3815-3821
-
-
Yvon, E.S.1
Vigouroux, S.2
Rousseau, R.F.3
Biagi, E.4
Amrolia, P.5
Dotti, G.6
-
26
-
-
0042834334
-
Notch signaling augments T cell responsiveness by enhancing CD25 expression
-
Adler S.H., Chiffoleau E., Xu L., Dalton N.M., Burg J.M., Wells A.D., et al. Notch signaling augments T cell responsiveness by enhancing CD25 expression. J. Immunol. 171:2003;2896-2903
-
(2003)
J. Immunol.
, vol.171
, pp. 2896-2903
-
-
Adler, S.H.1
Chiffoleau, E.2
Xu, L.3
Dalton, N.M.4
Burg, J.M.5
Wells, A.D.6
-
27
-
-
0033950375
-
Serrate1-induced notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells
-
Hoyne G.F., Le Roux I., Corsin-Jimenez M., Tan K., Dunne J., Forsyth L.M., et al. Serrate1-induced notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells. Int. Immunol. 12:2000;177-185
-
(2000)
Int. Immunol.
, vol.12
, pp. 177-185
-
-
Hoyne, G.F.1
Le Roux, I.2
Corsin-Jimenez, M.3
Tan, K.4
Dunne, J.5
Forsyth, L.M.6
-
28
-
-
0041331708
-
TCR-mediated notch signaling regulates proliferation and IFN-gamma production in peripheral T cells
-
Palaga T., Miele L., Golde T.E., Osborne B.A. TCR-mediated notch signaling regulates proliferation and IFN-gamma production in peripheral T cells. J. Immunol. 171:2003;3019-3024
-
(2003)
J. Immunol.
, vol.171
, pp. 3019-3024
-
-
Palaga, T.1
Miele, L.2
Golde, T.E.3
Osborne, B.A.4
-
29
-
-
0033796150
-
Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1
-
Aster J.C., Xu L., Karnell F.G., Patriub V., Pui J.C., Pear W.S. Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1. Mol. Cell. Biol. 20:2000;7505-7515
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7505-7515
-
-
Aster, J.C.1
Xu, L.2
Karnell, F.G.3
Patriub, V.4
Pui, J.C.5
Pear, W.S.6
-
30
-
-
0035796488
-
Separation of Notch1 promoted lineage commitment and expansion/ transformation in developing T cells
-
Allman D., Karnell F.G., Punt J.A., Bakkour S., Xu L., Myung P., et al. Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells. J. Exp. Med. 194:2001;99-106
-
(2001)
J. Exp. Med.
, vol.194
, pp. 99-106
-
-
Allman, D.1
Karnell, F.G.2
Punt, J.A.3
Bakkour, S.4
Xu, L.5
Myung, P.6
-
31
-
-
17744363445
-
Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength
-
Izon D.J., Punt J.A., Xu L., Karnell F.G., Allman D., Myung P.S., et al. Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength. Immunity. 14:2001;253-264
-
(2001)
Immunity
, vol.14
, pp. 253-264
-
-
Izon, D.J.1
Punt, J.A.2
Xu, L.3
Karnell, F.G.4
Allman, D.5
Myung, P.S.6
-
32
-
-
0037218811
-
Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling
-
Weng A.P., Nam Y., Wolfe M.S., Pear W.S., Griffin J.D., Blacklow S.C., et al. Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling. Mol. Cell. Biol. 23:2003;655-664
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 655-664
-
-
Weng, A.P.1
Nam, Y.2
Wolfe, M.S.3
Pear, W.S.4
Griffin, J.D.5
Blacklow, S.C.6
-
33
-
-
2142654263
-
Obligatory role for cooperative signaling by pre-T cell receptor and Notch during thymocyte differentiation
-
Ciofani M, Schmitt TM, Ciofani A, Michie AM, Cuburu N, Aublin A, et al. Obligatory role for cooperative signaling by pre-T cell receptor and Notch during thymocyte differentiation. J Immunol 2004;172:5230-9.
-
(2004)
J Immunol
, vol.172
, pp. 5230-5239
-
-
Ciofani, M.1
Schmitt, T.M.2
Ciofani, A.3
Michie, A.M.4
Cuburu, N.5
Aublin, A.6
-
34
-
-
0030297895
-
An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
-
Robey E., Chang D., Itano A., Cado D., Alexander H., Lans D., et al. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell. 87:1996;483-492
-
(1996)
Cell
, vol.87
, pp. 483-492
-
-
Robey, E.1
Chang, D.2
Itano, A.3
Cado, D.4
Alexander, H.5
Lans, D.6
-
35
-
-
0037710256
-
Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis
-
Beverly L.J., Capobianco A.J. Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis. Cancer Cell. 3:2003;551-564
-
(2003)
Cancer Cell
, vol.3
, pp. 551-564
-
-
Beverly, L.J.1
Capobianco, A.J.2
-
36
-
-
0037103148
-
A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development
-
Fowlkes B.J., Robey E.A. A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development. J. Immunol. 169:2002;1817-1821
-
(2002)
J. Immunol.
, vol.169
, pp. 1817-1821
-
-
Fowlkes, B.J.1
Robey, E.A.2
-
37
-
-
0043171113
-
Radiation-induced deletions in the 5′ end region of Notch1 lead to the formation of truncated proteins and are involved in the development of mouse thymic lymphomas
-
Tsuji H., Ishii-Ohba H., Ukai H., Katsube T., Ogiu T. Radiation-induced deletions in the 5′ end region of Notch1 lead to the formation of truncated proteins and are involved in the development of mouse thymic lymphomas. Carcinogenesis. 24:2003;1257-1268
-
(2003)
Carcinogenesis
, vol.24
, pp. 1257-1268
-
-
Tsuji, H.1
Ishii-Ohba, H.2
Ukai, H.3
Katsube, T.4
Ogiu, T.5
-
38
-
-
0034600850
-
Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice
-
Bellavia D., Campese A.F., Alesse E., Vacca A., Felli M.P., Balestri A., et al. Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice. EMBO J. 19:2000;3337-3348
-
(2000)
EMBO J.
, vol.19
, pp. 3337-3348
-
-
Bellavia, D.1
Campese, A.F.2
Alesse, E.3
Vacca, A.4
Felli, M.P.5
Balestri, A.6
-
39
-
-
0029819876
-
Transduction of Notch2 in feline leukemia virus-induced thymic lymphoma
-
Rohn J.L., Lauring A.S., Linenberger M.L., Overbaugh J. Transduction of Notch2 in feline leukemia virus-induced thymic lymphoma. J. Virol. 70:1996;8071-8080
-
(1996)
J. Virol.
, vol.70
, pp. 8071-8080
-
-
Rohn, J.L.1
Lauring, A.S.2
Linenberger, M.L.3
Overbaugh, J.4
-
40
-
-
0242721652
-
Activated Notch2 potentiates CD8 lineage maturation and promotes the selective development of B1 B cells
-
Witt C.M., Hurez V., Swindle C.S., Hamada Y., Klug C.A. Activated Notch2 potentiates CD8 lineage maturation and promotes the selective development of B1 B cells. Mol. Cell. Biol. 23:2003;8637-8650
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8637-8650
-
-
Witt, C.M.1
Hurez, V.2
Swindle, C.S.3
Hamada, Y.4
Klug, C.A.5
-
41
-
-
0032442040
-
Correlating notch signaling with thymocyte maturation
-
Deftos M.L., He Y.W., Ojala E.W., Bevan M.J. Correlating notch signaling with thymocyte maturation. Immunity. 9:1998;777-786
-
(1998)
Immunity
, vol.9
, pp. 777-786
-
-
Deftos, M.L.1
He, Y.W.2
Ojala, E.W.3
Bevan, M.J.4
-
42
-
-
0038079817
-
Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex
-
Nam Y., Weng A.P., Aster J.C., Blacklow S.C. Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex. J. Biol. Chem. 278:2003;21232-21239
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21232-21239
-
-
Nam, Y.1
Weng, A.P.2
Aster, J.C.3
Blacklow, S.C.4
-
43
-
-
0032403190
-
Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region
-
Kurooka H., Kuroda K., Honjo T. Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region. Nucleic Acids Res. 26:1998;5448-5455
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 5448-5455
-
-
Kurooka, H.1
Kuroda, K.2
Honjo, T.3
-
44
-
-
0027386233
-
Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei
-
Lieber T., Kidd S., Alcamo E., Corbin V., Young M.W. Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev. 7:1993;1949-1965
-
(1993)
Genes Dev.
, vol.7
, pp. 1949-1965
-
-
Lieber, T.1
Kidd, S.2
Alcamo, E.3
Corbin, V.4
Young, M.W.5
-
45
-
-
0036096912
-
Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line
-
Jeffries S., Robbins D.J., Capobianco A.J. Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line. Mol. Cell. Biol. 22:2002;3927-3941
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 3927-3941
-
-
Jeffries, S.1
Robbins, D.J.2
Capobianco, A.J.3
-
46
-
-
0036837899
-
Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors
-
Wu L., Sun T., Kobayashi K., Gao P., Griffin J.D. Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors. Mol. Cell. Biol. 22:2002;7688-7700
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7688-7700
-
-
Wu, L.1
Sun, T.2
Kobayashi, K.3
Gao, P.4
Griffin, J.D.5
-
47
-
-
0035895087
-
A novel Notch ligand Dll4 induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer
-
Yan X.Q., Sarmiento U., Sun Y., Huang G., Guo J., Juan T., et al. A novel Notch ligand Dll4 induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer. Blood. 98:2001;3793-3799
-
(2001)
Blood
, vol.98
, pp. 3793-3799
-
-
Yan, X.Q.1
Sarmiento, U.2
Sun, Y.3
Huang, G.4
Guo, J.5
Juan, T.6
-
48
-
-
0037105544
-
Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease
-
Dorsch M., Zheng G., Yowe D., Rao P., Wang Y., Shen Q., et al. Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease. Blood. 100:2002;2046-2055
-
(2002)
Blood
, vol.100
, pp. 2046-2055
-
-
Dorsch, M.1
Zheng, G.2
Yowe, D.3
Rao, P.4
Wang, Y.5
Shen, Q.6
-
49
-
-
85047699421
-
Vertebrate hairy and Enhancer of split related proteins: Transcriptional repressors regulating cellular differentiation and embryonic patterning
-
Davis R.L., Turner D.L. Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning. Oncogene. 20:2001;8342-8357
-
(2001)
Oncogene
, vol.20
, pp. 8342-8357
-
-
Davis, R.L.1
Turner, D.L.2
-
50
-
-
0033966375
-
A role for pref-1 and HES-1 in thymocyte development
-
Kaneta M., Osawa M., Sudo K., Nakauchi H., Farr A.G., Takahama Y. A role for pref-1 and HES-1 in thymocyte development. J. Immunol. 164:2000;256-264
-
(2000)
J. Immunol.
, vol.164
, pp. 256-264
-
-
Kaneta, M.1
Osawa, M.2
Sudo, K.3
Nakauchi, H.4
Farr, A.G.5
Takahama, Y.6
-
51
-
-
0033135269
-
The bHLH gene Hes1 is essential for expansion of early T cell precursors
-
Tomita K., Hattori M., Nakamura E., Nakanishi S., Minato N., Kageyama R. The bHLH gene Hes1 is essential for expansion of early T cell precursors. Genes Dev. 13:1999;1203-1210
-
(1999)
Genes Dev.
, vol.13
, pp. 1203-1210
-
-
Tomita, K.1
Hattori, M.2
Nakamura, E.3
Nakanishi, S.4
Minato, N.5
Kageyama, R.6
-
52
-
-
0037198653
-
Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations
-
Kawamata S., Du C., Li K., Lavau C. Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations. Oncogene. 21:2002;3855-3863
-
(2002)
Oncogene
, vol.21
, pp. 3855-3863
-
-
Kawamata, S.1
Du, C.2
Li, K.3
Lavau, C.4
-
53
-
-
18344388633
-
Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1
-
Izon D.J., Aster J.C., He Y., Weng A., Karnell F.G., Patriub V., et al. Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. Immunity. 16:2002;231-243
-
(2002)
Immunity
, vol.16
, pp. 231-243
-
-
Izon, D.J.1
Aster, J.C.2
He, Y.3
Weng, A.4
Karnell, F.G.5
Patriub, V.6
-
54
-
-
0035889891
-
Dysregulated expression of pre-Talpha reveals the opposite effects of pre-TCR at successive stages of T cell development
-
Lacorazza H.D., Porritt H.E., Nikolich-Zugich J. Dysregulated expression of pre-Talpha reveals the opposite effects of pre-TCR at successive stages of T cell development. J. Immunol. 167:2001;5689-5696
-
(2001)
J. Immunol.
, vol.167
, pp. 5689-5696
-
-
Lacorazza, H.D.1
Porritt, H.E.2
Nikolich-Zugich, J.3
-
55
-
-
0030752361
-
E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas
-
Bain G., Engel I., Robanus Maandag E.C., te Riele H.P., Voland J.R., Sharp L.L., et al. E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas. Mol. Cell. Biol. 17:1997;4782-4791
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4782-4791
-
-
Bain, G.1
Engel, I.2
Robanus Maandag, E.C.3
Te Riele, H.P.4
Voland, J.R.5
Sharp, L.L.6
-
56
-
-
0032168564
-
LMO T-cell translocation oncogenes typify genes activated by chromosomal translocations that alter transcription and developmental processes
-
Rabbitts T.H. LMO T-cell translocation oncogenes typify genes activated by chromosomal translocations that alter transcription and developmental processes. Genes Dev. 12:1998;2651-2657
-
(1998)
Genes Dev.
, vol.12
, pp. 2651-2657
-
-
Rabbitts, T.H.1
-
57
-
-
0027083415
-
Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split
-
Sasai Y., Kageyama R., Tagawa Y., Shigemoto R., Nakanishi S. Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev. 6:1992;2620-2634
-
(1992)
Genes Dev.
, vol.6
, pp. 2620-2634
-
-
Sasai, Y.1
Kageyama, R.2
Tagawa, Y.3
Shigemoto, R.4
Nakanishi, S.5
-
58
-
-
0031923281
-
Notch inhibition of E47 supports the existence of a novel signaling pathway
-
Ordentlich P., Lin A., Shen C.P., Blaumueller C., Matsuno K., Artavanis-Tsakonas S., et al. Notch inhibition of E47 supports the existence of a novel signaling pathway. Mol. Cell. Biol. 18:1998;2230-2239
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2230-2239
-
-
Ordentlich, P.1
Lin, A.2
Shen, C.P.3
Blaumueller, C.4
Matsuno, K.5
Artavanis-Tsakonas, S.6
-
59
-
-
0242556813
-
Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities
-
Nie L., Xu M., Vladimirova A., Sun X.H. Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities. EMBO J. 22:2003;5780-5792
-
(2003)
EMBO J.
, vol.22
, pp. 5780-5792
-
-
Nie, L.1
Xu, M.2
Vladimirova, A.3
Sun, X.H.4
-
60
-
-
0348133609
-
Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma
-
Talora C., Campese A.F., Bellavia D., Pascucci M., Checquolo S., Groppioni M., et al. Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma. EMBO Rep. 4:2003;1067-1071
-
(2003)
EMBO Rep.
, vol.4
, pp. 1067-1071
-
-
Talora, C.1
Campese, A.F.2
Bellavia, D.3
Pascucci, M.4
Checquolo, S.5
Groppioni, M.6
-
61
-
-
0029994434
-
The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice
-
Carrasco D., Rizzo C.A., Dorfman K., Bravo R. The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice. EMBO J. 15:1996;3640-3650
-
(1996)
EMBO J.
, vol.15
, pp. 3640-3650
-
-
Carrasco, D.1
Rizzo, C.A.2
Dorfman, K.3
Bravo, R.4
-
62
-
-
0035887655
-
Notch-1 regulates NF-kappaB activity in hemopoietic progenitor cells
-
Cheng P., Zlobin A., Volgina V., Gottipati S., Osborne B., Simel E.J., et al. Notch-1 regulates NF-kappaB activity in hemopoietic progenitor cells. J. Immunol. 167:2001;4458-4467
-
(2001)
J. Immunol.
, vol.167
, pp. 4458-4467
-
-
Cheng, P.1
Zlobin, A.2
Volgina, V.3
Gottipati, S.4
Osborne, B.5
Simel, E.J.6
-
63
-
-
0031594575
-
NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa
-
Oswald F., Liptay S., Adler G., Schmid R.M. NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa. Mol. Cell. Biol. 18:1998;2077-2088
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2077-2088
-
-
Oswald, F.1
Liptay, S.2
Adler, G.3
Schmid, R.M.4
-
64
-
-
0035399803
-
Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain
-
Wang J., Shelly L., Miele L., Boykins R., Norcross M.A., Guan E. Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain. J. Immunol. 167:2001;289-295
-
(2001)
J. Immunol.
, vol.167
, pp. 289-295
-
-
Wang, J.1
Shelly, L.2
Miele, L.3
Boykins, R.4
Norcross, M.A.5
Guan, E.6
-
65
-
-
0033577768
-
Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors
-
Bash J., Zong W.X., Banga S., Rivera A., Ballard D.W., Ron Y., et al. Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors. EMBO J. 18:1999;2803-2811
-
(1999)
EMBO J.
, vol.18
, pp. 2803-2811
-
-
Bash, J.1
Zong, W.X.2
Banga, S.3
Rivera, A.4
Ballard, D.W.5
Ron, Y.6
-
66
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
Bos J.L. ras oncogenes in human cancer: a review. Cancer Res. 49:1989;4682-4689
-
(1989)
Cancer Res.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
67
-
-
0036734148
-
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells
-
Weijzen S., Rizzo P., Braid M., Vaishnav R., Jonkheer S.M., Zlobin A., et al. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat. Med. 8:2002;979-986
-
(2002)
Nat. Med.
, vol.8
, pp. 979-986
-
-
Weijzen, S.1
Rizzo, P.2
Braid, M.3
Vaishnav, R.4
Jonkheer, S.M.5
Zlobin, A.6
-
68
-
-
0031895560
-
Cyclin D1 and human neoplasia
-
Donnellan R., Chetty R. Cyclin D1 and human neoplasia. Mol. Pathol. 51:1998;1-7
-
(1998)
Mol. Pathol.
, vol.51
, pp. 1-7
-
-
Donnellan, R.1
Chetty, R.2
-
69
-
-
0034902568
-
Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): Implication for cell cycle disruption in transformation by Notch(ic)
-
Ronchini C., Capobianco A.J. Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic). Mol. Cell. Biol. 21:2001;5925-5934
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5925-5934
-
-
Ronchini, C.1
Capobianco, A.J.2
-
70
-
-
9144229104
-
Requirement for cyclin D3 in lymphocyte development and T cell leukemias
-
Sicinska E., Aifantis I., Le Cam L., Swat W., Borowski C., Yu Q., et al. Requirement for cyclin D3 in lymphocyte development and T cell leukemias. Cancer Cell. 4:2003;451-461
-
(2003)
Cancer Cell
, vol.4
, pp. 451-461
-
-
Sicinska, E.1
Aifantis, I.2
Le Cam, L.3
Swat, W.4
Borowski, C.5
Yu, Q.6
-
71
-
-
0036745068
-
Orphan nuclear receptors in T lymphocyte development
-
He Y.W. Orphan nuclear receptors in T lymphocyte development. J. Leukoc. Biol. 72:2002;440-446
-
(2002)
J. Leukoc. Biol.
, vol.72
, pp. 440-446
-
-
He, Y.W.1
-
72
-
-
0033556251
-
Protective effects of notch-1 on TCR-induced apoptosis
-
Jehn B.M., Bielke W., Pear W.S., Osborne B.A. Protective effects of notch-1 on TCR-induced apoptosis. J. Immunol. 162:1999;635-638
-
(1999)
J. Immunol.
, vol.162
, pp. 635-638
-
-
Jehn, B.M.1
Bielke, W.2
Pear, W.S.3
Osborne, B.A.4
-
73
-
-
1642576036
-
The anti-apoptotic effect of notch-1 requires p56lck-dependent, Akt/PKB-mediated signalling in T cells
-
Sade H, Krishna S, Sarin A. The anti-apoptotic effect of notch-1 requires p56lck-dependent, Akt/PKB-mediated signalling in T cells. J Biol Chem 2003;279:2937-44.
-
(2003)
J Biol Chem
, vol.279
, pp. 2937-2944
-
-
Sade, H.1
Krishna, S.2
Sarin, A.3
-
74
-
-
0034284471
-
A carboxy-terminal deletion mutant of Notch1 accelerates lymphoid oncogenesis in E2A-PBX1 transgenic mice
-
Feldman B.J., Hampton T., Cleary M.L. A carboxy-terminal deletion mutant of Notch1 accelerates lymphoid oncogenesis in E2A-PBX1 transgenic mice. Blood. 96:2000;1906-9013
-
(2000)
Blood
, vol.96
, pp. 1906-9013
-
-
Feldman, B.J.1
Hampton, T.2
Cleary, M.L.3
-
75
-
-
0027306001
-
Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor
-
Rebay I., Fehon R.G., Artavanis-Tsakonas S. Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor. Cell. 74:1993;319-329
-
(1993)
Cell
, vol.74
, pp. 319-329
-
-
Rebay, I.1
Fehon, R.G.2
Artavanis-Tsakonas, S.3
-
76
-
-
0025883261
-
Carboxy-terminal truncation activates glp-1 protein to specify vulval fates in Caenorhabditis elegans
-
Mango S.E., Maine E.M., Kimble J. Carboxy-terminal truncation activates glp-1 protein to specify vulval fates in Caenorhabditis elegans. Nature. 352:1991;811-815
-
(1991)
Nature
, vol.352
, pp. 811-815
-
-
Mango, S.E.1
Maine, E.M.2
Kimble, J.3
-
77
-
-
0029670476
-
Interaction between Wingless and Notch signaling pathways mediated by dishevelled
-
Axelrod J.D., Matsuno K., Artavanis-Tsakonas S., Perrimon N. Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science. 271:1996;1826-1832
-
(1996)
Science
, vol.271
, pp. 1826-1832
-
-
Axelrod, J.D.1
Matsuno, K.2
Artavanis-Tsakonas, S.3
Perrimon, N.4
-
78
-
-
1642499734
-
{Beta}-catenin is dispensable for hematopoiesis and lymphopoiesis
-
Cobas M., Wilson A., Ernst B., Mancini S.J., MacDonald H.R., Kemler R., et al. {Beta}-catenin is dispensable for hematopoiesis and lymphopoiesis. J. Exp. Med. 199:2004;221-229
-
(2004)
J. Exp. Med.
, vol.199
, pp. 221-229
-
-
Cobas, M.1
Wilson, A.2
Ernst, B.3
Mancini, S.J.4
MacDonald, H.R.5
Kemler, R.6
-
79
-
-
0029808295
-
Frequent proviral insertional mutagenesis of NOTCH1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and NOTCH1 for oncogenesis
-
Girard L., Hanna Z., Beaulieu N., Hoemann C.D., Simard C., Kozak C.A., et al. Frequent proviral insertional mutagenesis of NOTCH1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and NOTCH1 for oncogenesis. Genes Dev. 10:1996;1930-1944
-
(1996)
Genes Dev.
, vol.10
, pp. 1930-1944
-
-
Girard, L.1
Hanna, Z.2
Beaulieu, N.3
Hoemann, C.D.4
Simard, C.5
Kozak, C.A.6
-
80
-
-
0034024722
-
Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice
-
Hoemann C.D., Beaulieu N., Girard L., Rebai N., Jolicoeur P. Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice. Mol. Cell. Biol. 20:2000;3831-3842
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3831-3842
-
-
Hoemann, C.D.1
Beaulieu, N.2
Girard, L.3
Rebai, N.4
Jolicoeur, P.5
-
81
-
-
0033636743
-
Evidence that an IRES within the Notch2 coding region can direct expression of a nuclear form of the protein
-
Lauring A.S., Overbaugh J. Evidence that an IRES within the Notch2 coding region can direct expression of a nuclear form of the protein. Mol. Cell. 6:2000;939-945
-
(2000)
Mol. Cell
, vol.6
, pp. 939-945
-
-
Lauring, A.S.1
Overbaugh, J.2
-
82
-
-
0037353821
-
Over-expression of short isoforms of Helios in patients with adult T-cell leukaemia/lymphoma
-
Fujii K., Ishimaru F., Nakase K., Tabayashi T., Kozuka T., Naoki K., et al. Over-expression of short isoforms of Helios in patients with adult T-cell leukaemia/lymphoma. Br. J. Haematol. 120:2003;986-989
-
(2003)
Br. J. Haematol.
, vol.120
, pp. 986-989
-
-
Fujii, K.1
Ishimaru, F.2
Nakase, K.3
Tabayashi, T.4
Kozuka, T.5
Naoki, K.6
-
83
-
-
0032761116
-
Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia
-
Sun L., Goodman P.A., Wood C.M., Crotty M.L., Sensel M., Sather H., et al. Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia. J. Clin. Oncol. 17:1999;3753-3766
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 3753-3766
-
-
Sun, L.1
Goodman, P.A.2
Wood, C.M.3
Crotty, M.L.4
Sensel, M.5
Sather, H.6
-
84
-
-
1442285891
-
Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency
-
Kang-Decker N., Tong C., Boussouar F., Baker D.J., Xu W., Leontovich A.A., et al. Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency. Cancer Cell. 5:2004;177-189
-
(2004)
Cancer Cell
, vol.5
, pp. 177-189
-
-
Kang-Decker, N.1
Tong, C.2
Boussouar, F.3
Baker, D.J.4
Xu, W.5
Leontovich, A.A.6
-
85
-
-
0345863840
-
RTCGD: Retroviral tagged cancer gene database
-
Akagi K., Suzuki T., Stephens R.M., Jenkins N.A., Copeland N.G. RTCGD: retroviral tagged cancer gene database. Nucleic Acids Res. 32:2004;D523-D527
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Akagi, K.1
Suzuki, T.2
Stephens, R.M.3
Jenkins, N.A.4
Copeland, N.G.5
-
86
-
-
0034602419
-
Presenilin-1 and -2 are molecular targets for gamma-secretase inhibitors
-
Seiffert D., Bradley J.D., Rominger C.M., Rominger D.H., Yang F., Meredith J.E. Jr., et al. Presenilin-1 and -2 are molecular targets for gamma-secretase inhibitors. J. Biol. Chem. 275:2000;34086-34091
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34086-34091
-
-
Seiffert, D.1
Bradley, J.D.2
Rominger, C.M.3
Rominger, D.H.4
Yang, F.5
Meredith Jr., J.E.6
-
87
-
-
0035912829
-
Gamma-secretase inhibitors repress thymocyte development
-
Hadland B.K., Manley N.R., Su D., Longmore G.D., Moore C.L., Wolfe M.S., et al. Gamma-secretase inhibitors repress thymocyte development. Proc. Natl. Acad. Sci. U.S.A. 98:2001;7487-7491
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 7487-7491
-
-
Hadland, B.K.1
Manley, N.R.2
Su, D.3
Longmore, G.D.4
Moore, C.L.5
Wolfe, M.S.6
-
88
-
-
0036727125
-
Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling
-
Fortini M.E. Gamma-secretase-mediated proteolysis in cell-surface- receptor signalling. Nat. Rev. Mol. Cell. Biol. 3:2002;673-684
-
(2002)
Nat. Rev. Mol. Cell. Biol.
, vol.3
, pp. 673-684
-
-
Fortini, M.E.1
-
89
-
-
0037271081
-
Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila
-
Micchelli C.A., Esler W.P., Kimberly W.T., Jack C., Berezovska O., Kornilova A., et al. Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila. FASEB J. 17:2003;79-81
-
(2003)
FASEB J.
, vol.17
, pp. 79-81
-
-
Micchelli, C.A.1
Esler, W.P.2
Kimberly, W.T.3
Jack, C.4
Berezovska, O.5
Kornilova, A.6
-
90
-
-
11144355129
-
Chronic treatment with the {gamma}-secretase inhibitor LY-411,575 inhibits {beta}-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation
-
Wong G.T., Manfra D., Poulet F.M., Zhang Q., Josien H., Bara T., et al. Chronic treatment with the {gamma}-secretase inhibitor LY-411,575 inhibits {beta}-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation. J. Biol. Chem. 279:2004;12876-12882
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 12876-12882
-
-
Wong, G.T.1
Manfra, D.2
Poulet, F.M.3
Zhang, Q.4
Josien, H.5
Bara, T.6
-
91
-
-
0042630561
-
Secretases as targets for the treatment of Alzheimer's disease: The prospects
-
Dewachter I., Van Leuven F. Secretases as targets for the treatment of Alzheimer's disease: the prospects. Lancet Neurol. 1:2002;409-416
-
(2002)
Lancet Neurol.
, vol.1
, pp. 409-416
-
-
Dewachter, I.1
Van Leuven, F.2
-
92
-
-
0036234698
-
Cooperativity between mutations in tyrosine kinases and in hematopoietic transcription factors in AML
-
Deguchi K., Gilliland D.G. Cooperativity between mutations in tyrosine kinases and in hematopoietic transcription factors in AML. Leukemia. 16:2002;740-744
-
(2002)
Leukemia
, vol.16
, pp. 740-744
-
-
Deguchi, K.1
Gilliland, D.G.2
|