Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Volumn 17, Issue 1, 2003, Pages 79-81

  Micchelli, Craig A ^a   Esler, William P ^a   Kimberly, W Taylor ^a   Jack, Christine ^a   Berezovska, Oksana ^a   Kornilova, Anna ^a   Hyman, Bradley T ^a   Perrimon, Norbert ^a   Wolfe, Michael S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDE; DROSOPHILA PROTEIN; MEMBRANE PROTEIN; N (N (3,5 DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT BUTYL ESTER; N-(N-(3,5-DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT-BUTYL ESTER; NOTCH PROTEIN, DROSOPHILA; NOTCH RECEPTOR; PRESENILIN; PROTEINASE; PROTEINASE INHIBITOR; PSN PROTEIN, DROSOPHILA; SECRETASE;

ACTIVE TRANSPORT; ALZHEIMER DISEASE; ANIMAL; ARTICLE; DROSOPHILA; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FORELIMB; GENETICS; HISTOLOGY; KINETICS; METABOLISM; MUTATION; PHENOTYPE; PRENATAL DEVELOPMENT; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; DIPEPTIDES; DROSOPHILA; DROSOPHILA PROTEINS; ENDOPEPTIDASES; KINETICS; MEMBRANE PROTEINS; MUTATION; PHENOTYPE; PRESENILINS; PROTEASE INHIBITORS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; WING;

MLCS; MLOWN;

EID: 0037271081     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.02-0394fje     Document Type: Article

References (0)