Activated Notch2 Potentiates CD8 Lineage Maturation and Promotes the Selective Development of B1 B Cells

Molecular and Cellular Biology

Volumn 23, Issue 23, 2003, Pages 8637-8650

  Witt, Colleen M ^a   Hurez, Vincent ^b   Swindle, C Scott ^a   Hamada, Yoshio ^c   Klug, Christopher A ^a  

^a The University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

^c NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; NOTCH RECEPTOR; NOTCH2 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL LINEAGE; CELL MATURATION; CONTROLLED STUDY; HEMATOPOIESIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T CELL LEUKEMIA; T LYMPHOCYTE; THYMOCYTE;

ANIMALS; B-LYMPHOCYTE SUBSETS; BASE SEQUENCE; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; DNA; GENE DOSAGE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIESIS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; RECEPTOR, NOTCH2; RECEPTORS, CELL SURFACE;

ANIMALIA;

EID: 0242721652     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.23.8637-8650.2003     Document Type: Article

References (40)

1. Bellavia, D., A. F. Campese, E. Alesse, A. Vacca, M. P. Felli, A. Balestri, A. Stoppacciaro, C. Tiveron, L. Tatangelo, M. Giovarelli, C. Gaetano, L. Ruco, E. S. Hoffman, A. C. Hayday, U. Lendahl, L. Frati, A. Gulino, and I. Screpanti. 2000. Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice. EMBO J. 19:3337-3348.
2. Bigas, A., D. I. Martin, and L. A. Milner. 1998. Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines. Mol. Cell Biol. 18:2324-2333.
3. Cariappa, A., H. C. Liou, B. H. Horwitz, and S. Pillai. 2000. Nuclear factor kappa B is required for the development of marginal zone B lymphocytes. J. Exp. Med. 192:1175-1182.
4. Cheng, P., A. Zlobin, V. Volgina, S. Gottipati, B. Osborne, E. J. Simel, L. Miele, and D. I. Gabrilovich. 2001. Notch-1 regulates NF-kappaB activity in hemopoietic progenitor cells. J. Immunol. 167:4458-4467.
5. Correia-Neves, M., D. Mathis, and C. Benoist. 2001. A molecular chart of thymocyte positive selection. Eur. J. Immunol. 31:2583-2592.
6. de Guzman, C. G., A. J. Warren, Z. Zhang, L. Gartland, P. Erickson, H. Drabkin, S. W. Hiebert, and C. A. Klug. 2002. Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation. Mol. Cell Biol. 22:5506-5517.
7. Deftos, M. L., E. Huang, E. W. Ojala, K. A. Forbush, and M. J. Bevan. 2000. Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes. Immunity 13:73-84.
8. Doerfler, P., M. S. Shearman, and R. M. Perlmutter. 2001. Presenilin-dependent gamma-secretase activity modulates thymocyte development. Proc. Natl. Acad. Sci. USA 98:9312-9317.
9. Fagarasan, S., N. Watanabe, and T. Honjo. 2000. Generation, expansion, migration and activation of mouse B1 cells. Immunol. Rev. 176:205-215.
10. Feng, C., K. J. Woodside, B. A. Vance, D. El-Khoury, M. Canelles, J. Lee, R. Gress, B. J. Fowlkes, E. W. Shores, and P. E. Love. 2002. A potential role for CD69 in thymocyte emigration. Int. Immunol. 14:535-544.
11. Fowlkes, B. J., and E. A. Robey. 2002. A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development. J. Immunol. 169:1817-1821.
12. Hadland, B. K., N. R. Manley, D. Su, G. D. Longmore, C. L. Moore, M. S. Wolfe, E. H. Schroeter, and R. Kopan. 2001. Gamma-secretase inhibitors repress thymocyte development. Proc. Natl. Acad. Sci. USA 98:7487-7491.
13. Hamada, Y., Y. Kadokawa, M. Okabe, M. Ikawa, J. R. Coleman, and Y. Tsujimoto. 1999. Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Development 126:3415-3424.
14. Hardy, R. R., C. E. Carmack, S. A. Shinton, J. D. Kemp, and K. Hayakawa. 1991. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173:1213-1225.
15. Hardy, R. R., Y. S. Li, D. Allman, M. Asano, M. Gui, and K. Hayakawa. 2000. B-cell commitment, development and selection. Immunol. Rev. 175:23-32.
16. Hawley, R. G. 1994. High-titer retroviral vectors for efficient transduction of functional genes into murine hematopoietic stem cells. Ann. N. Y. Acad. Sci. 716:327-330.
17. Ingles-Esteve, J., L. Espinosa, L. A. Milner, C. Caelles, and A. Bigas. 2001. Phosphorylation of Ser2078 modulates the Notch2 function in 32D cell differentiation. J. Biol. Chem. 276:44873-44880.
18. Izon, D. J., J. A. Punt, L. Xu, F. G. Karnell, D. Allman, P. S. Myung, N. J. Boerth, J. C. Pui, G. A. Koretzky, and W. S. Pear. 2001. Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength. Immunity 14:253-264.
19. Jones, P., G. May, L. Healy, J. Brown, G. Hoyne, S. Delassus, and T. Enver. 1998. Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells. Blood 92:1505-1511.
20. Kimble, J., and P. Simpson. 1997. The LIN-12/Notch signaling pathway and its regulation. Annu. Rev. Cell Dev. Biol. 13:333-361.
21. Koch, U., T. A. Lacombe, D. Holland, J. L. Bowman, B. L. Cohen, S. E. Egan, and C. J. Guidos. 2001. Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1. Immunity 15:225-236.
22. Martin, F., and J. F. Kearney. 2000. B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory." Immunol. Rev. 175:70-79.
23. Martin, F., and J. F. Kearney. 2000. Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk. Immunity 12:39-49.
24. Martin, F., A. M. Oliver, and J. F. Kearney. 2001. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14:617-629.
25. Milner, L. A., R. Kopan, D. I. Martin, and I. D. Bernstein. 1994. A human homologue of the Drosophila developmental gene, Notch, is expressed in CD34+ hematopoietic precursors. Blood 83:2057-2062.
26. Morimura, T., R. Goitsuka, Y. Zhang, I. Salto, M. Reth, and D. Kitamura. 2000. Cell cycle arrest and apoptosis induced by Notch1 in B cells. J. Biol. Chem. 275:36523-36531.
27. Nakayama, T., D. J. Kasprowicz, M. Yamashita, L. A. Schubert, G. Gillard, M. Kimura, A. Didierlaurent, H. Koseki, and S. F. Ziegler. 2002. The generation of mature, single-positive thymocytes in vivo is dysregulated by CD69 blockade or overexpression. J. Immunol. 168:87-94.
28. Oliver, A. M., F. Martin, and J. F. Kearney. 1999. IgMhighCD21high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells. J. Immunol. 162:7198-7207.
29. Oswald, F., S. Liptay, G. Adler, and R. M. Schmid. 1998. NF-κB2 is a putative target gene of activated Notch-1 via RBP-Jκ. Mol. Cell Biol. 18:2077-2088.
30. Pui, J. C., D. Allman, L. Xu, S. DeRocco, F. G. Karnell, S. Bakkour, J. Y. Lee, T. Kadesch, R. R. Hardy, J. C. Aster, and W. S. Pear. 1999. Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity 11:299-308.
31. Radtke, F., A. Wilson, G. Stark, M. Bauer, J. van Meerwijk, H. R. MacDonald, and M. Aguet. 1999. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 10:547-558.
32. Robey, E., D. Chang, A. Itano, D. Cado, H. Alexander, D. Lans, G. Weinmaster, and P. Salmon. 1996. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell 87:483-492.
33. Robey, E., and B. J. Fowlkes. 1994. Selective events in T cell development. Annu. Rev. Immunol. 12:675-705.
34. Rothstein, T. L. 2002. Cutting edge commentary: two B-1 or not to be one. J. Immunol. 168:4257-4261.
35. Scherer, D. C., J. A. Brockman, H. H. Bendall, G. M. Zhang, D. W. Ballard, and E. M. Oltz. 1996. Corepression of RelA and c-rel inhibits immunoglobulin kappa gene transcription and rearrangement in precursor B lymphocytes. Immunity 5:563-574.
36. Schmitt, T. M., and J. C. Zuniga-Pflucker. 2002. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity 17:749-756.
37. Walker, L., A. Carlson, H. T. Tan-Pertel, G. Weinmaster, and J. Gasson. 2001. The notch receptor and its ligands are selectively expressed during hematopoietic development in the mouse. Stem Cells 19:543-552.
38. Wang, J., L. Shelly, L. Miele, R. Boykins, M. A. Norcross, and E. Guan. 2001. Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain. J. Immunol. 167:289-295.
39. Wang, J. H., N. Avitahl, A. Cariappa, C. Friedrich, T. Ikeda, A. Renold, K. Andrikopoulos, L. Liang, S. Pillai, B. A. Morgan, and K. Georgopoulos. 1998. Aiolos regulates B cell activation and maturation to effector state. Immunity 9:543-553.
40. Wolfer, A., T. Bakker, A. Wilson, M. Nicolas, V. Ioannidis, D. R. Littman, P. P. Lee, C. B. Wilson, W. Held, H. R. MacDonald, and F. Radtke. 2001. Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. Nat. Immunol. 2:235-241.