A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development

Journal of Immunology

Volumn 169, Issue 4, 2002, Pages 1817-1821

  Fowlkes, B J ^a   Robey, Ellen A ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NOTCH RECEPTOR; NOTCH1 RECEPTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THYMOCYTE; TRANSGENIC MOUSE;

EID: 0037103148     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.4.1817     Document Type: Article

References (30)

1. Deficient T cell fate specification in mice with an induced inactivation of Notch 1
2. Notch1 expression in early lymphopoiesis influences B versus T lineage determination
3. Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1
4. Notch signaling in lymphocyte development
5. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
6. Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development
7. Notch-1 regulates NF-κB activity in hemopoietic progenitor cells
8. Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: Distinct ligand-receptor interactions in intrathymic T cell development
9. Presenilin-dependent γ-secretase activity modulates thymocyte development
10. γ-secretase inbibitors repress thymocyte development
11. + T-cell lineage fate
12. Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes
13. Mice lacking major histocompatibility complex class I and class II molecules
14. - thymocytes are functionally immature
15. Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1
16. MHC recognition in thymic development: Distinct parallel pathways for survival and lineage commitment
17. Constitutive activation of NF-κB and T-cell leukemia/lymphoma in Notch3 transgenic mice
18. + thymocytes by modulating TCR signal strength
19. Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region
20. Structure/function studies of lin-12/Notch proteins
21. Notch and the CD4 versus CD8 lineage decision
22. Protective effects of notch-1 on TCR-induced apoptosis
23. Correlating notch signaling with thymocyte maturation
24. Cell cycle arrest and apoptosis induced by Notch1 in B cells
25. Intrathymic T cell development and selection proceeds normally in the absence of glucocorticoid receptor signaling
26. Signaling downstream of activated mammalian Notch
27. The Notch signalling pathway is required for enhancer of split bHLH protein expression during neurogenesis in the drosophila embryo
28. Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1: Negative autoregulation through the multiple N box elements
29. Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase