-
1
-
-
46249132454
-
-
2nd edition; Chabner, B. A, Longo, D. L, Ed, J. B. Lippincott: Philadelphia
-
Tew, K.; Colvin, M.; Chabner, B. A. Alkylating agents. In Cancer chemotherapy: principles and practise, 2nd edition; Chabner, B. A.; Longo, D. L., Ed.; J. B. Lippincott: Philadelphia, 1995.
-
(1995)
A. Alkylating agents. In Cancer chemotherapy: Principles and practise
-
-
Tew, K.1
Colvin, M.2
Chabner, B.3
-
2
-
-
0025924488
-
-
Dolan, M. E.; Mitchell, R. B.; Mummert, C.; Moschel, R. C.; Pegg, A. E. Cancer Res., 1991, 51, 3367.;
-
(1991)
Cancer Res
, vol.51
, pp. 3367
-
-
Dolan, M.E.1
Mitchell, R.B.2
Mummert, C.3
Moschel, R.C.4
Pegg, A.E.5
-
3
-
-
0014672640
-
-
b) Loveless, A. Nature, 1969, 223, 206.;
-
(1969)
Nature
, vol.223
, pp. 206
-
-
Loveless, A.1
-
5
-
-
0022399410
-
-
d) Saffhill, R.; Margison, G. P.; O'Connor, P. J. Biochim. Biophys. Acta., 1985, 823, 111.
-
(1985)
Biochim. Biophys. Acta
, vol.823
, pp. 111
-
-
Saffhill, R.1
Margison, G.P.2
O'Connor, P.J.3
-
8
-
-
0242331221
-
-
Christmann, M.; Tomicic, M. T.; Roos, W. P.; Kaina, B. Toxicology, 2003, 193, 3.;
-
(2003)
Toxicology
, vol.193
, pp. 3
-
-
Christmann, M.1
Tomicic, M.T.2
Roos, W.P.3
Kaina, B.4
-
10
-
-
4243189666
-
-
c) D'Incalci, M.; Citti, L.; Taverna, P.; Cata Pano, C. V. Cancer Treatment Reviews, 1988, 51, 3367.;
-
(1988)
Cancer Treatment Reviews
, vol.51
, pp. 3367
-
-
D'Incalci, M.1
Citti, L.2
Taverna, P.3
Cata Pano, C.V.4
-
11
-
-
1542752198
-
-
d) McElhinney, R.S.; McMurry, T.B.H.; Margison, G.P. Mini Reviews in Medicinal Chemistry, 2003, 3, 471.
-
(2003)
Mini Reviews in Medicinal Chemistry
, vol.3
, pp. 471
-
-
McElhinney, R.S.1
McMurry, T.B.H.2
Margison, G.P.3
-
13
-
-
0027434870
-
-
Pegg, A. E.; Boosalis, M.; Samson, L.; Moschel, R. C.; Byers, T.; Swenn, K.; Dolan, M. E. Biochemistry, 1993, 32, 11998.
-
(1993)
Biochemistry
, vol.32
, pp. 11998
-
-
Pegg, A.E.1
Boosalis, M.2
Samson, L.3
Moschel, R.C.4
Byers, T.5
Swenn, K.6
Dolan, M.E.7
-
14
-
-
0028794564
-
-
Pegg, A. E.; Dolan, M. E.; Moschel, R. C. Prog. Nucl. Acid. Res. Mol. Biol., 1995, 51, 167.
-
(1995)
Prog. Nucl. Acid. Res. Mol. Biol
, vol.51
, pp. 167
-
-
Pegg, A.E.1
Dolan, M.E.2
Moschel, R.C.3
-
15
-
-
0034880822
-
-
Liu L.; Spiro T. P.; Qin X.; Majka S.; Haaga J.; Schupp J.; Willson J.K.; Gerson S. L. Clin. Cancer. Res., 2001, 8, 2318.
-
(2001)
Clin. Cancer. Res
, vol.8
, pp. 2318
-
-
Liu, L.1
Spiro, T.P.2
Qin, X.3
Majka, S.4
Haaga, J.5
Schupp, J.6
Willson, J.K.7
Gerson, S.L.8
-
16
-
-
0036570292
-
-
Quinn J. A.; Pluda J.; Dolan M. E.; Delaney S.; Kaplan R.; Rich J. N.; Friedman A. H.; Reardon D. A.; Sampson J.H.; Colvin O. M.; Haglund M. M; Pegg A. E.; Moschel R. C.; McLendon R. E.; Provenzale J. M.; Gururangan S.; Tourt-Uhlig S.; Herndon J. E. 2nd; Bigner D. D.; Friedman H. S. J. Clin. Oncol., 2002, 20, 2277.
-
(2002)
J. Clin. Oncol
, vol.20
, pp. 2277
-
-
Quinn, J.A.1
Pluda, J.2
Dolan, M.E.3
Delaney, S.4
Kaplan, R.5
Rich, J.N.6
Friedman, A.H.7
Reardon, D.A.8
Sampson, J.H.9
Colvin, O.M.10
Haglund, M.M.11
Pegg, A.E.12
Moschel, R.C.13
McLendon, R.E.14
Provenzale, J.M.15
Gururangan, S.16
Tourt-Uhlig, S.17
Herndon 2nd, J.E.18
Bigner, D.D.19
Friedman, H.S.20
more..
-
17
-
-
0026485170
-
-
Moschel, R. C.; McDougall, M. G.; Dolan, M. E.; Stine, L.; Pegg, A. E. J. Med. Chem., 1992, 35, 4486.
-
(1992)
J. Med. Chem
, vol.35
, pp. 4486
-
-
Moschel, R.C.1
McDougall, M.G.2
Dolan, M.E.3
Stine, L.4
Pegg, A.E.5
-
18
-
-
0025196019
-
-
Dolan, M. E.; Moschel, R. C.; Pegg, A. E. Proc. Natl. Acad. Sci. USA., 1990, 87, 5368.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5368
-
-
Dolan, M.E.1
Moschel, R.C.2
Pegg, A.E.3
-
19
-
-
0028167176
-
-
Chae, M.-Y.; McDougall, M. G.; Dolan, M. E.; Sween, K.; Pegg. A. E.; Moschel, R. C. J. Med. Chem., 1994, 37, 342.
-
(1994)
J. Med. Chem
, vol.37
, pp. 342
-
-
Chae, M.-Y.1
McDougall, M.G.2
Dolan, M.E.3
Sween, K.4
Pegg, A.E.5
Moschel, R.C.6
-
20
-
-
0028989770
-
-
Chae, M.-Y.; Swenn, K.; Kanugula, S.; Dolan, M. E.; Pegg, A. E.; Moschel, R. C. J. Med. Chem., 1995, 38, 359.
-
(1995)
J. Med. Chem
, vol.38
, pp. 359
-
-
Chae, M.-Y.1
Swenn, K.2
Kanugula, S.3
Dolan, M.E.4
Pegg, A.E.5
Moschel, R.C.6
-
21
-
-
0028171184
-
-
Dolan, M. E.; Chae, M.-Y.; Pegg, A. E.; Mullen, J. H.; Friedman, H. S.; Moschel, R. C. Cancer Res., 1994, 54, 5123.
-
(1994)
Cancer Res
, vol.54
, pp. 5123
-
-
Dolan, M.E.1
Chae, M.-Y.2
Pegg, A.E.3
Mullen, J.H.4
Friedman, H.S.5
Moschel, R.C.6
-
22
-
-
46249098043
-
-
Shealy, Y. F.; Clayton, J. D.; O'Dell, C. A.; Montgomery, J. A. J. Org. Chem., 1962, 27, 4516.
-
(1962)
J. Org. Chem
, vol.27
, pp. 4516
-
-
Shealy, Y.F.1
Clayton, J.D.2
O'Dell, C.A.3
Montgomery, J.A.4
-
23
-
-
0032542080
-
-
McElhinney, R. S.; Bonnelly, D. J.; McCormick, J. E.; Kelly, J.; Watson, A. J.; Rafferty, J. A.; Elder, R. H.; Middleton, M. R.; Willington, M. A.; McMurry, T. B. H. J. Med. Chem. 1998, 41, 5265.
-
(1998)
J. Med. Chem
, vol.41
, pp. 5265
-
-
McElhinney, R.S.1
Bonnelly, D.J.2
McCormick, J.E.3
Kelly, J.4
Watson, A.J.5
Rafferty, J.A.6
Elder, R.H.7
Middleton, M.R.8
Willington, M.A.9
McMurry, T.B.H.10
-
24
-
-
0034650791
-
-
Middleton, M. R.; Kelly, J.; Thatcher, N.; Donelly, D. J.; McElhinney, R. S.; McMurry, T. B.; McCormick, J. E.; Margison, G. P. Int. J. Cancer, 2000, 85, 248.
-
(2000)
Int. J. Cancer
, vol.85
, pp. 248
-
-
Middleton, M.R.1
Kelly, J.2
Thatcher, N.3
Donelly, D.J.4
McElhinney, R.S.5
McMurry, T.B.6
McCormick, J.E.7
Margison, G.P.8
-
25
-
-
46249127134
-
-
Arris, C. E.; Bleasdale, C.; Calvert, A. H.; Curtin, N. J.; Dalby, C.; Golding, B. T.; Griffin, R. J.; Lunn, J. M.; Major, G. N.; Newell, D. R. Anti. Cancer Drug. Des., 1994, 9, 359.
-
(1994)
Anti. Cancer Drug. Des
, vol.9
, pp. 359
-
-
Arris, C.E.1
Bleasdale, C.2
Calvert, A.H.3
Curtin, N.J.4
Dalby, C.5
Golding, B.T.6
Griffin, R.J.7
Lunn, J.M.8
Major, G.N.9
Newell, D.R.10
-
26
-
-
0028172654
-
-
Crone, T. M.; Goodtzova, K.; Edara, S.; Pegg, A. E. Cancer Res., 1994, 54, 6221.;
-
(1994)
Cancer Res
, vol.54
, pp. 6221
-
-
Crone, T.M.1
Goodtzova, K.2
Edara, S.3
Pegg, A.E.4
-
27
-
-
0032056361
-
-
b) Xu-Welliver, M.; Kanugula, S.; Pegg, A. E. Cancer Res., 1998, 59, 1936.;
-
(1998)
Cancer Res
, vol.59
, pp. 1936
-
-
Xu-Welliver, M.1
Kanugula, S.2
Pegg, A.E.3
-
28
-
-
0033118477
-
-
Xu-Welliver, M.; Leitao, J.; Kanugula, S.; Pegg, A. E. Cancer Res., 1999, 59, 1514.;
-
(1999)
Cancer Res
, vol.59
, pp. 1514
-
-
Xu-Welliver, M.1
Leitao, J.2
Kanugula, S.3
Pegg, A.E.4
-
29
-
-
0032866823
-
-
Xu-Welliver, M.; Leitao, J.; Kanugula, S.; Meehan, W. J.; Pegg, A. E. Biochem. Pharmacol., 1999, 58, 1279.
-
(1999)
Biochem. Pharmacol
, vol.58
, pp. 1279
-
-
Xu-Welliver, M.1
Leitao, J.2
Kanugula, S.3
Meehan, W.J.4
Pegg, A.E.5
-
30
-
-
0034597607
-
-
Griffin, R. J.; Arris, C. E.; Bleasdaly, C.; Boyle, F. T.; Calvert, A. H.; Curtin, N. J.; Dalby, C.; Kanugula, S.; Lembicz, N. K.; Newell, D. R.; Pegg, A. E.; Golding, B. T. J. Med. Chem., 2000, 43, 4071.
-
(2000)
J. Med. Chem
, vol.43
, pp. 4071
-
-
Griffin, R.J.1
Arris, C.E.2
Bleasdaly, C.3
Boyle, F.T.4
Calvert, A.H.5
Curtin, N.J.6
Dalby, C.7
Kanugula, S.8
Lembicz, N.K.9
Newell, D.R.10
Pegg, A.E.11
Golding, B.T.12
-
33
-
-
0035935676
-
-
Reinhard, J.; Hull, W. E.; von der Lieth, C.-W.; Eichhorn, U.; Kliem, H.-C.; Kaina, B.; Wiessler, M. J. Med. Chem., 2001, 44, 4050.
-
(2001)
J. Med. Chem
, vol.44
, pp. 4050
-
-
Reinhard, J.1
Hull, W.E.2
von der Lieth, C.-W.3
Eichhorn, U.4
Kliem, H.-C.5
Kaina, B.6
Wiessler, M.7
-
34
-
-
0035427042
-
-
Reinhard, J.; Eichhorn, U.; Wiessler, M.; Kaina, B. Int. J. Cancer, 2001, 93, 373.
-
(2001)
Int. J. Cancer
, vol.93
, pp. 373
-
-
Reinhard, J.1
Eichhorn, U.2
Wiessler, M.3
Kaina, B.4
-
35
-
-
0034721195
-
-
Arris, C. E.; Boyle, T.; Calvert, H.; Curtin, N. J.; Endicott, J. A.; Garman, E. F.; Gibson, A. E.; Golding, B. T.; Grant, S.; Griffin, R. J.; Jewsbury, P.; Johnson, L. N.; Lawrie, A. M.; Newell, D. R.; Noble, M. E. M.; Sausville, E. A.; Schulz, R.; Yu, W. J. Med. Chem., 2000, 43, 2797.
-
(2000)
J. Med. Chem
, vol.43
, pp. 2797
-
-
Arris, C.E.1
Boyle, T.2
Calvert, H.3
Curtin, N.J.4
Endicott, J.A.5
Garman, E.F.6
Gibson, A.E.7
Golding, B.T.8
Grant, S.9
Griffin, R.J.10
Jewsbury, P.11
Johnson, L.N.12
Lawrie, A.M.13
Newell, D.R.14
Noble, M.E.M.15
Sausville, E.A.16
Schulz, R.17
Yu, W.18
-
37
-
-
0033036758
-
-
b) Meijer, I.; Leclerc, L.; Leost, M. Pharmacol. Ther., 1999, 82, 279.
-
(1999)
Pharmacol. Ther
, vol.82
, pp. 279
-
-
Meijer, I.1
Leclerc, L.2
Leost, M.3
-
38
-
-
0036682024
-
-
Gibson, A. E. G.; Arris, C. E.; Bentley, J.; Boyle, T.; Curtin, N. J.; Davis, T. G.; Endicott, J. A.; Golding, B. T.; Grant, S.; Griffin, R. J.; Jewsbury, P.; Johnson, L. N.; Mesguiche, V.; Newell, D. R.; Noble, M. E. M.; Tucker, J. A.; Whitfield, H. J. J. Med. Chem., 2002, 45, 3381.
-
(2002)
J. Med. Chem
, vol.45
, pp. 3381
-
-
Gibson, A.E.G.1
Arris, C.E.2
Bentley, J.3
Boyle, T.4
Curtin, N.J.5
Davis, T.G.6
Endicott, J.A.7
Golding, B.T.8
Grant, S.9
Griffin, R.J.10
Jewsbury, P.11
Johnson, L.N.12
Mesguiche, V.13
Newell, D.R.14
Noble, M.E.M.15
Tucker, J.A.16
Whitfield, H.J.17
-
39
-
-
0032918488
-
-
Imbach, P.; Capraro, H.-G.; Furet, P.; Mett, H.; Meyer, T.; Zimmermann, Bioorg. Med. Chem. Lett., 1999, 9, 91.
-
(1999)
Bioorg. Med. Chem. Lett
, vol.9
, pp. 91
-
-
Imbach, P.1
Capraro, H.-G.2
Furet, P.3
Mett, H.4
Meyer, T.5
Zimmermann6
-
40
-
-
0030869845
-
-
Schow, S. R.; Mackman, R. I.; Blum, C. L.; Brooks, E.; Horsma, A. G.; Joly, A.; Kerwar, S. S.; Lee, G.; Shiffman, D.; Nelson, M. G.; Wang, X.; Wick, M. M.; Zhang, X.; Lum, R. T. Bioorg. Med. Chem. Lett., 1997, 7, 2697.
-
(1997)
Bioorg. Med. Chem. Lett
, vol.7
, pp. 2697
-
-
Schow, S.R.1
Mackman, R.I.2
Blum, C.L.3
Brooks, E.4
Horsma, A.G.5
Joly, A.6
Kerwar, S.S.7
Lee, G.8
Shiffman, D.9
Nelson, M.G.10
Wang, X.11
Wick, M.M.12
Zhang, X.13
Lum, R.T.14
-
41
-
-
0032492705
-
-
Legraverend, M.; Ludwig, O.; Bisagni, E.; Leclerc, S.; Meijer, L. Bioorg. Med. Chem. Lett., 1998, 8, 793.
-
(1998)
Bioorg. Med. Chem. Lett
, vol.8
, pp. 793
-
-
Legraverend, M.1
Ludwig, O.2
Bisagni, E.3
Leclerc, S.4
Meijer, L.5
-
42
-
-
0242500884
-
-
Chen, X.; Kern, E. R.; Drach, J. C.; Gullen, E.; Cheng, Y.-C.; Zemlicka, J. J. Med. Chem., 2003, 46, 1531.
-
(2003)
J. Med. Chem
, vol.46
, pp. 1531
-
-
Chen, X.1
Kern, E.R.2
Drach, J.C.3
Gullen, E.4
Cheng, Y.-C.5
Zemlicka, J.6
-
43
-
-
0028866318
-
-
Vince, R.; Kilama, J.; Pham, P. T.; Beers, S. A.; Bowdon, B. J.; Keith, K. A.; Parker, W. B. Nucleosides Nucleotides, 1995, 14, 1703.
-
(1995)
Nucleosides Nucleotides
, vol.14
, pp. 1703
-
-
Vince, R.1
Kilama, J.2
Pham, P.T.3
Beers, S.A.4
Bowdon, B.J.5
Keith, K.A.6
Parker, W.B.7
-
44
-
-
18644376454
-
-
Schirrmacher, R.; Mühlhausen, U.; Wängler, B.; Schirrmacher, E.; Reinhard, J.; Nagel, G.; Kaina, B.; Piel, M.; Wießler, M.; Rösch, F. Tetrahedron Lett., 2002, 43, 6301.
-
(2002)
Tetrahedron Lett
, vol.43
, pp. 6301
-
-
Schirrmacher, R.1
Mühlhausen, U.2
Wängler, B.3
Schirrmacher, E.4
Reinhard, J.5
Nagel, G.6
Kaina, B.7
Piel, M.8
Wießler, M.9
Rösch, F.10
-
45
-
-
0036152457
-
-
Schirrmacher, R.; Nesseler, E.; Hamkens, W.; Eichhorn, U.; Schreckenberger, M.; Kaina, B.; Rösch, F. Appl. Radiat. Isot., 2002, 56, 511.
-
(2002)
Appl. Radiat. Isot
, vol.56
, pp. 511
-
-
Schirrmacher, R.1
Nesseler, E.2
Hamkens, W.3
Eichhorn, U.4
Schreckenberger, M.5
Kaina, B.6
Rösch, F.7
-
46
-
-
0033652540
-
-
Vaidyanathan, G.; Affleck, D. J.; Cavazos, C. M.; Johnson, S. P.; Shankar, S.; Friedman, H. S.; Colvin, M. O.; Zalutsky, M. R. Bioconjugate Chem., 2000, 11, 868.
-
(2000)
Bioconjugate Chem
, vol.11
, pp. 868
-
-
Vaidyanathan, G.1
Affleck, D.J.2
Cavazos, C.M.3
Johnson, S.P.4
Shankar, S.5
Friedman, H.S.6
Colvin, M.O.7
Zalutsky, M.R.8
-
47
-
-
0028805598
-
-
Mounetou, E.; Cussac, C.; Mathieu, F.; Maurizis, J.-C.; Labarre, P.; Moreau, M.-F.; Veyre, A.; Madelmont, J.-C. J. Label. Compd. Radiopharm., 1995, 36, 1215.
-
(1995)
J. Label. Compd. Radiopharm
, vol.36
, pp. 1215
-
-
Mounetou, E.1
Cussac, C.2
Mathieu, F.3
Maurizis, J.-C.4
Labarre, P.5
Moreau, M.-F.6
Veyre, A.7
Madelmont, J.-C.8
-
48
-
-
46249114738
-
-
18F-alcohol concentration would be extremely substoichiometric.
-
18F-alcohol concentration would be extremely substoichiometric.
-
-
-
-
49
-
-
0036941302
-
-
Zheng, Q.-H.; Liu, X.; Fei, X.; Wang, J.-Q.; Ohannesian, D. W.; Erickson, L. C.; Lee Stone, K.; Martinez, T. D.; Miller, K. D.; Hutchins, G. D. J. Label. Compd. Radiopharm., 2002, 45, 1239.
-
(2002)
J. Label. Compd. Radiopharm
, vol.45
, pp. 1239
-
-
Zheng, Q.-H.1
Liu, X.2
Fei, X.3
Wang, J.-Q.4
Ohannesian, D.W.5
Erickson, L.C.6
Lee Stone, K.7
Martinez, T.D.8
Miller, K.D.9
Hutchins, G.D.10
-
50
-
-
0037269850
-
-
Liu, X.; Zheng, Q.-H.; Hutchins, G. D.; Fei, X.; Erickson, L. C.; Miller, K. D.; Mock, B. H.; Glick-Wilson, B. E.; Winkle, W. L.; Stone, K. L.; Carlson, K. A. Synth. Commun., 2003, 33, 941.
-
(2003)
Synth. Commun
, vol.33
, pp. 941
-
-
Liu, X.1
Zheng, Q.-H.2
Hutchins, G.D.3
Fei, X.4
Erickson, L.C.5
Miller, K.D.6
Mock, B.H.7
Glick-Wilson, B.E.8
Winkle, W.L.9
Stone, K.L.10
Carlson, K.A.11
-
51
-
-
0037293854
-
-
Liu, X.; Zheng, Q.-H.; Fei, X.; Wang, J.-Q.; Ohannesian, D. W.; Erickson, L. C.; Stone, K. L.; Hutchins, G. D. Bioorg. Med. Chem. Lett., 2003, 13, 641.
-
(2003)
Bioorg. Med. Chem. Lett
, vol.13
, pp. 641
-
-
Liu, X.1
Zheng, Q.-H.2
Fei, X.3
Wang, J.-Q.4
Ohannesian, D.W.5
Erickson, L.C.6
Stone, K.L.7
Hutchins, G.D.8
-
53
-
-
0028990878
-
-
Ciocco, G. M.; Moschel, R. C.; Chae, M.-Y.; McLaughlin, P. J.; Zagon, I. S.; Pegg, A. E. Cancer Res., 1995, 55, 4085.
-
(1995)
Cancer Res
, vol.55
, pp. 4085
-
-
Ciocco, G.M.1
Moschel, R.C.2
Chae, M.-Y.3
McLaughlin, P.J.4
Zagon, I.S.5
Pegg, A.E.6
-
54
-
-
0026733827
-
-
Madelmont, J. C.; Cussa, C.; Dupuy, J. M.; Rapp, M.; Labarre, P.; Chabarad, J. L.; Maurizis, J. C.; Sauzieres, J.; Baudry, J. P.; Godeneche, D.; Veyre, A. J. Label. Compd. Radiopharm., 1992, 31, 793.
-
(1992)
J. Label. Compd. Radiopharm
, vol.31
, pp. 793
-
-
Madelmont, J.C.1
Cussa, C.2
Dupuy, J.M.3
Rapp, M.4
Labarre, P.5
Chabarad, J.L.6
Maurizis, J.C.7
Sauzieres, J.8
Baudry, J.P.9
Godeneche, D.10
Veyre, A.11
-
55
-
-
0023818437
-
-
Dolan, M. E.; Scicchitano, D.; Pegg, A. E. Cancer Res., 1988, 48, 1184.
-
(1988)
Cancer Res
, vol.48
, pp. 1184
-
-
Dolan, M.E.1
Scicchitano, D.2
Pegg, A.E.3
-
56
-
-
0026480143
-
-
Souliotis, V. L.; Zongza, V.; Nikolopoulos, V.; Dimitriadis, G. L. Comp. Biochem. Physiol., 1992, 101B, 269.
-
(1992)
Comp. Biochem. Physiol
, vol.101 B
, pp. 269
-
-
Souliotis, V.L.1
Zongza, V.2
Nikolopoulos, V.3
Dimitriadis, G.L.4
-
57
-
-
0031934819
-
-
Lolli, M.; Medana, C.; Romagnano, S.; Castoldi, F.; Pozzoli, S.; Vago, F.; Fanelli, R.; Airoldi, L. J. Label. Compd. Radiopharm., 1998, 3, 243.
-
(1998)
J. Label. Compd. Radiopharm
, vol.3
, pp. 243
-
-
Lolli, M.1
Medana, C.2
Romagnano, S.3
Castoldi, F.4
Pozzoli, S.5
Vago, F.6
Fanelli, R.7
Airoldi, L.8
-
58
-
-
84978547023
-
-
Beynon, J. H.; Hopkinson, J. A.; Williams, A. E. Org. Mass Spectrom., 1968, 1, 169.
-
(1968)
Org. Mass Spectrom
, vol.1
, pp. 169
-
-
Beynon, J.H.1
Hopkinson, J.A.2
Williams, A.E.3
-
59
-
-
46249129230
-
-
Jpn. Kokai Tokkyo Koho JP 05213952 A2 930824 Heisei; Chem. Abstr, 1994, 120, 8412
-
Sato; Jpn. Kokai Tokkyo Koho JP 05213952 A2 930824 Heisei; Chem. Abstr., 1994, 120, 8412.
-
-
-
Sato1
-
60
-
-
46249103040
-
-
Eur. Pat. Appl. EP 543095 A2 930526;, 180812
-
Igi, T. Hayashi; Eur. Pat. Appl. EP 543095 A2 930526; Chem. Abstr., 1993, 119, 180812.
-
(1993)
Chem. Abstr
, vol.119
-
-
Igi, T.H.1
-
61
-
-
46249111986
-
-
PCT Int. Appl. WO 92113859 A1 920820;, 233720
-
Hanson, C. PCT Int. Appl. WO 92113859 A1 920820; Chem. Abstr., 1992, 117, 233720.
-
(1992)
Chem. Abstr
, vol.117
-
-
Hanson, C.1
-
62
-
-
46249110843
-
-
Int. Appl. WO 9315075 A1 930805;, 30779
-
Killen, R. J. PCP Int. Appl. WO 9315075 A1 930805; Chem. Abstr., 1994, 120, 30779.
-
(1994)
Chem. Abstr
, vol.120
-
-
Killen, R.J.P.1
-
63
-
-
0032798601
-
-
Zhou, J.; Tsai, J.-Y.; Bouhadir, K.; Shevlin, P. B. Synth. Commun., 1999, 29, 3003.
-
(1999)
Synth. Commun
, vol.29
, pp. 3003
-
-
Zhou, J.1
Tsai, J.-Y.2
Bouhadir, K.3
Shevlin, P.B.4
-
64
-
-
46249133824
-
-
Unpublished results from our laboratory show that reaction times of more than 2 h lead to a total mono deacetylation in 9-position of the 2-amino-purine (guanine).
-
Unpublished results from our laboratory show that reaction times of more than 2 h lead to a total mono deacetylation in 9-position of the 2-amino-purine (guanine).
-
-
-
-
67
-
-
46249106902
-
-
The authors stated that crystallization of the product set in when the solution was evaporated. To our experience it is essential to evaporate at room temperature because higher temperatures using a vacuum evaporator lead to unwanted side reactions and reduced the yield significantly. In the worst case, no crystallization was observed
-
The authors stated that crystallization of the product set in when the solution was evaporated. To our experience it is essential to evaporate at room temperature because higher temperatures using a vacuum evaporator lead to unwanted side reactions and reduced the yield significantly. In the worst case, no crystallization was observed.
-
-
-
-
68
-
-
46249124105
-
-
Simon, A. B.; Brit. Pat. 767216, 1957; Chem. Abst. 1957, 51, 14796d.
-
Simon, A. B.; Brit. Pat. 767216, 1957; Chem. Abst. 1957, 51, 14796d.
-
-
-
-
69
-
-
46249109639
-
-
US 2815346, 6417b
-
Burroughs Wellcome & Co. US 2815346, 1955; Chem. Abst. 1958, 52, 6417b.
-
(1955)
Chem. Abst
, vol.52
-
-
-
70
-
-
46249113609
-
-
These unpublished results were obtained in our laboratory. The reaction time of bubbling chlorine through the solution should not exceed 10 h. It is essential to reduce the of the reaction mixture at room temperature (25°C) by half. Then precipitation of 3 set in.
-
These unpublished results were obtained in our laboratory. The reaction time of bubbling chlorine through the solution should not exceed 10 h. It is essential to reduce the volume of the reaction mixture at room temperature (25°C) by half. Then precipitation of 3 set in.
-
-
-
-
71
-
-
0003188807
-
-
Beaman, A. G.; Gerster, J. F.; Robins, R. K. J. Org. Chem. 1962, 27, 986.
-
(1962)
J. Org. Chem
, vol.27
, pp. 986
-
-
Beaman, A.G.1
Gerster, J.F.2
Robins, R.K.3
-
72
-
-
0000875021
-
-
Daves, G. D. Jr.; Noell, C. W.; Robins, R. K.; Koppel, H. C.; Beaman, A. G. J. Am. Chem. Soc., 1960, 82, 2633.
-
(1960)
J. Am. Chem. Soc
, vol.82
, pp. 2633
-
-
Daves Jr., G.D.1
Noell, C.W.2
Robins, R.K.3
Koppel, H.C.4
Beaman, A.G.5
-
73
-
-
0000565506
-
-
Bowels, W. A.; Schneider, F. H.; Lewis, L. R.; Robins, R. K. J. Med. Chem., 1963, 6, 471.
-
(1963)
J. Med. Chem
, vol.6
, pp. 471
-
-
Bowels, W.A.1
Schneider, F.H.2
Lewis, L.R.3
Robins, R.K.4
-
75
-
-
0028223265
-
-
Linn, J. A.; McLean, E. W.; Kelly, J. L. J. Chem. Soc., Chem. Commun., 1994, 913.
-
(1994)
J. Chem. Soc., Chem. Commun
, pp. 913
-
-
Linn, J.A.1
McLean, E.W.2
Kelly, J.L.3
-
76
-
-
0036195915
-
-
Schirrmacher, R.; Wängler, B.; Schirrmacher, E.; August, T.; Rösch, F. Synthesis, 2002, 4, 538.
-
(2002)
Synthesis
, vol.4
, pp. 538
-
-
Schirrmacher, R.1
Wängler, B.2
Schirrmacher, E.3
August, T.4
Rösch, F.5
-
77
-
-
46249087675
-
-
The authors would like to indicate that the published yield of the trimethyl ammonium salt (4) of 79 % can be enhanced up to 95 % by reducing the final DMSO solution by half before adding diethyl ether.
-
The authors would like to indicate that the published yield of the trimethyl ammonium salt (4) of 79 % can be enhanced up to 95 % by reducing the final DMSO solution by half before adding diethyl ether.
-
-
-
-
78
-
-
0025075348
-
-
Ashwell, M.; Bleasdale, C.; Golding, B. T.; O'Neill, I. K. J. Chem. Soc., Chem. Commun., 1990, 955.
-
(1990)
J. Chem. Soc., Chem. Commun
, pp. 955
-
-
Ashwell, M.1
Bleasdale, C.2
Golding, B.T.3
O'Neill, I.K.4
-
79
-
-
46249114193
-
-
6-ether moiety.
-
6-ether moiety.
-
-
-
-
80
-
-
33748529352
-
-
Lembicz, N. K.; Grant, S.; Clegg, W.; Griffin, R. J.; Heath, S. L.; Golding, B. T. J. Chem. Soc., Perkin Trans 1, 1997, 1, 185.
-
(1997)
J. Chem. Soc., Perkin Trans 1
, vol.1
, pp. 185
-
-
Lembicz, N.K.1
Grant, S.2
Clegg, W.3
Griffin, R.J.4
Heath, S.L.5
Golding, B.T.6
-
81
-
-
0033190638
-
-
Långström, B.; Kihlberg, T.; Bergstöm, M.; Antoni, G.; Björkman, M.; Forngren, B. H.; Forngren, T.; Hartvig, P.; Markides, K.; Yngve, U.; Ögren, M. Acta. Chem. Scand., 1999, 53, 651.
-
(1999)
Acta. Chem. Scand
, vol.53
, pp. 651
-
-
Långström, B.1
Kihlberg, T.2
Bergstöm, M.3
Antoni, G.4
Björkman, M.5
Forngren, B.H.6
Forngren, T.7
Hartvig, P.8
Markides, K.9
Yngve, U.10
Ögren, M.11
-
83
-
-
46249113909
-
-
Adamiak, R. W.; Biala, E.; Skalski, B. Angew. Chem., 1985, 97, 1046.
-
(1985)
Angew. Chem
, vol.97
, pp. 1046
-
-
Adamiak, R.W.1
Biala, E.2
Skalski, B.3
-
84
-
-
0010859453
-
-
Adamiak, R. W.; Biala, E.; Gdaniec, Z.; Mielewczyk, S. Chemica Scripta, 1986, 26, 3.
-
(1986)
Chemica Scripta
, vol.26
, pp. 3
-
-
Adamiak, R.W.1
Biala, E.2
Gdaniec, Z.3
Mielewczyk, S.4
-
85
-
-
33745469772
-
-
Huynh-Dinh, T.; d'Estaintot, L.; Allard, P.; Igolen, J. Tetrahedron Lett., 1985, 26, 431.
-
(1985)
Tetrahedron Lett
, vol.26
, pp. 431
-
-
Huynh-Dinh, T.1
d'Estaintot, L.2
Allard, P.3
Igolen, J.4
-
87
-
-
0000056478
-
-
Skalski, B.; Paszyk, S.; Adamina, R. W.; Steer, R. P.; Verrall, R. E. Can. J. Chem., 1990, 68, 2164.
-
(1990)
Can. J. Chem
, vol.68
, pp. 2164
-
-
Skalski, B.1
Paszyk, S.2
Adamina, R.W.3
Steer, R.P.4
Verrall, R.E.5
-
88
-
-
0000733886
-
-
Höfle, G.; Steglich, W.; Vorbrüggen, H. Angew. Chem., 1978, 90, 602;
-
(1978)
Angew. Chem
, vol.90
, pp. 602
-
-
Höfle, G.1
Steglich, W.2
Vorbrüggen, H.3
-
89
-
-
0001557720
-
-
b) Hassner, A.; Krepski, L. R.; Alexanian, V. Tetrahedron, 1978, 34, 2069;
-
(1978)
Tetrahedron
, vol.34
, pp. 2069
-
-
Hassner, A.1
Krepski, L.R.2
Alexanian, V.3
-
91
-
-
0037225952
-
-
Keppler, A.; Gendreizig, S.; Gronemeyer, T.; Pick, H.; Vogel, H.; Johnsson, K. Nat. Biotechnol., 2003, 21, 86.
-
(2003)
Nat. Biotechnol
, vol.21
, pp. 86
-
-
Keppler, A.1
Gendreizig, S.2
Gronemeyer, T.3
Pick, H.4
Vogel, H.5
Johnsson, K.6
-
93
-
-
0026736786
-
-
Jenny, T. F.; Schneider, K. C.; Benner, S. A. Nucleosides & Nucleotides, 1992, 11, 1257.
-
(1992)
Nucleosides & Nucleotides
, vol.11
, pp. 1257
-
-
Jenny, T.F.1
Schneider, K.C.2
Benner, S.A.3
-
95
-
-
0029860623
-
-
Loeppky, R. N.; Yu, Li.; Gu, F.; Ye, Q. J. Am. Chem. Soc., 1996, 118, 10995.
-
(1996)
J. Am. Chem. Soc
, vol.118
, pp. 10995
-
-
Loeppky, R.N.1
Yu, L.2
Gu, F.3
Ye, Q.4
-
96
-
-
0027408262
-
-
Safadi, M.; Bindna, D.; Williams, T.; Moschel, R. C.; Sella, V. J. Int. J. Pharm., 1993, 90, 239.
-
(1993)
Int. J. Pharm
, vol.90
, pp. 239
-
-
Safadi, M.1
Bindna, D.2
Williams, T.3
Moschel, R.C.4
Sella, V.J.5
-
97
-
-
0000242998
-
-
Gao, X.; Gaffney, B. L.; Hadden, S.; Jones, R. A. J. Org. Chem., 1986, 51, 755.
-
(1986)
J. Org. Chem
, vol.51
, pp. 755
-
-
Gao, X.1
Gaffney, B.L.2
Hadden, S.3
Jones, R.A.4
-
99
-
-
0000851918
-
-
Kamimura, T.; Tsuchiya, M.; Urakami, K.-I.; Kouro, K.; Sekine, M.; Shinozaki, K.; Miura, K.-I.; Hata, T. J. Am. Chem. Soc., 1984, 106, 4552.
-
(1984)
J. Am. Chem. Soc
, vol.106
, pp. 4552
-
-
Kamimura, T.1
Tsuchiya, M.2
Urakami, K.-I.3
Kouro, K.4
Sekine, M.5
Shinozaki, K.6
Miura, K.-I.7
Hata, T.8
-
100
-
-
0036131028
-
-
Balu, N.; Gamcsik, M. P.; Colvin, M. E.; Colvin, O. M.; Dolan, M. E.; Ludeman, S. M. Chem. Res. Toxicol., 2002, 15, 380.
-
(2002)
Chem. Res. Toxicol
, vol.15
, pp. 380
-
-
Balu, N.1
Gamcsik, M.P.2
Colvin, M.E.3
Colvin, O.M.4
Dolan, M.E.5
Ludeman, S.M.6
-
101
-
-
0033605936
-
-
Chida, N.; Susuki, T.; Tanaka, S.; Yamada, I. Tetrahedron Lett., 1999, 40, 2573.
-
(1999)
Tetrahedron Lett
, vol.40
, pp. 2573
-
-
Chida, N.1
Susuki, T.2
Tanaka, S.3
Yamada, I.4
-
102
-
-
0038717142
-
-
Xu, M.; Giacomo, F. D.; Paterson, D. E.; George, T. G.; Vasella, A. Chem. Commun., 2003, 1452.
-
(2003)
Chem. Commun
, pp. 1452
-
-
Xu, M.1
Giacomo, F.D.2
Paterson, D.E.3
George, T.G.4
Vasella, A.5
-
103
-
-
84977277519
-
-
Thermal processes: a Fuchs, H.; Gottlieb, M.; Pfleiderer, W. Chem. Ber., 1978, 111, 982.;
-
Thermal processes: a) Fuchs, H.; Gottlieb, M.; Pfleiderer, W. Chem. Ber., 1978, 111, 982.;
-
-
-
-
104
-
-
0024323119
-
-
b) Shamin, M. T.; Ukena, D.; Padgett, W, L.; Daly, J. W. J. Med. Chem., 1989, 32, 1231.;
-
(1989)
J. Med. Chem
, vol.32
, pp. 1231
-
-
Shamin, M.T.1
Ukena, D.2
Padgett, W.L.3
Daly, J.W.4
-
105
-
-
0029929275
-
-
c) Rybár, A.; Alföldi, J.; Federonko, M.; Kozák, J. Synthesis, 1996, 459.;
-
(1996)
Synthesis
, pp. 459
-
-
Rybár, A.1
Alföldi, J.2
Federonko, M.3
Kozák, J.4
-
106
-
-
0014711926
-
-
reduction: a Kempter, F. E.; Rokos, H.; Pfleiderer, W. Chem. Ber., 1970, 103, 885.;
-
reduction: a) Kempter, F. E.; Rokos, H.; Pfleiderer, W. Chem. Ber., 1970, 103, 885.;
-
-
-
-
107
-
-
0016637420
-
-
b) Kavai, I.; Mead, L. M.; Drobniak, J.; Zakrzewski, S. F. J. Med. Chem., 1975, 18, 272.;
-
(1975)
J. Med. Chem
, vol.18
, pp. 272
-
-
Kavai, I.1
Mead, L.M.2
Drobniak, J.3
Zakrzewski, S.F.4
-
108
-
-
0032868185
-
-
c) Moore, A. G.; Schow, S. R.; Lum, R. T.; Nelson, M. G.; Melville, C. R. Synthesis, 1999, 1123.;
-
(1999)
Synthesis
, pp. 1123
-
-
Moore, A.G.1
Schow, S.R.2
Lum, R.T.3
Nelson, M.G.4
Melville, C.R.5
-
109
-
-
33947482661
-
-
Mannich base: Taylor, E. C. and Garcia, E. E. J. Am. Chem. Soc.; 1964, 86, 4720.;
-
Mannich base: Taylor, E. C. and Garcia, E. E. J. Am. Chem. Soc.; 1964, 86, 4720.;
-
-
-
-
110
-
-
46249109383
-
-
Vilsmeier-Haak reagents: a Yoneda, F.; Higuchi, M.; Matsumura, T.; Senga, K. Bull. Chem. Soc. Jpn., 1973, 1836.;
-
Vilsmeier-Haak reagents: a) Yoneda, F.; Higuchi, M.; Matsumura, T.; Senga, K. Bull. Chem. Soc. Jpn., 1973, 1836.;
-
-
-
-
111
-
-
0026541638
-
-
b) Melguizo, M.; Nogueras, M.; Sánches, A. J. Org. Chem., 1992, 57, 559.;
-
(1992)
J. Org. Chem
, vol.57
, pp. 559
-
-
Melguizo, M.1
Nogueras, M.2
Sánches, A.3
-
112
-
-
0016909005
-
-
1,1-dimethylhydrazones: Yoneda, F.; Nagamatsu, T. J. Chem. Soc., Perkin Trans. 1, 1976, 35, 1547.
-
1,1-dimethylhydrazones: Yoneda, F.; Nagamatsu, T. J. Chem. Soc., Perkin Trans. 1, 1976, 35, 1547.
-
-
-
-
115
-
-
0000565506
-
-
Bowels, W. A.; Schneider, F. H.; Lewis, L. R.; Robins, R. K. J. Med. Chem., 1963, 6, 471.
-
(1963)
J. Med. Chem
, vol.6
, pp. 471
-
-
Bowels, W.A.1
Schneider, F.H.2
Lewis, L.R.3
Robins, R.K.4
-
116
-
-
46249106376
-
The temperature should not exceed 80°C and the benzylacohol must be freshly distilled and oxygen free
-
Optimization of this method was achieved in our laboratory, and the benzylacohol must be freshly distilled and oxygen free
-
Optimization of this method was achieved in our laboratory. The temperature should not exceed 80°C and the benzylacohol must be freshly distilled and oxygen free.
-
-
-
-
117
-
-
46249105345
-
-
These observations were made in our laboratory during optimization of the literature procedure
-
These observations were made in our laboratory during optimization of the literature procedure.
-
-
-
-
118
-
-
0030037022
-
-
Koyama, K.; Hitomi, K.; Terashima, I.; Kohda, K. Chem. Pharm. Bull., 1996, 44, 1395.
-
(1996)
Chem. Pharm. Bull
, vol.44
, pp. 1395
-
-
Koyama, K.1
Hitomi, K.2
Terashima, I.3
Kohda, K.4
-
120
-
-
0021999232
-
-
MacCross, M.; Chen, A.; Tolman, R. L. Tetrahedron Lett., 1985, 26, 1815.
-
(1985)
Tetrahedron Lett
, vol.26
, pp. 1815
-
-
MacCross, M.1
Chen, A.2
Tolman, R.L.3
-
121
-
-
4243171350
-
-
Barth; C.; Seitz, O.; Kunz, H.; Z. Naturforsch., 2004, 59b, 802.
-
(2004)
Z. Naturforsch
, vol.59 b
, pp. 802
-
-
Barth, C.1
Seitz, O.2
Kunz, H.3
|