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Volumn 44, Issue 24, 2001, Pages 4050-4061

Monosaccharide-linked inhibitors of O6-methylguanine-DNA methyltransferase (MGMT): Synthesis, molecular modeling, and structure-activity relationships

(7) Reinhard, J a Hull, W E a Von der Lieth, C W a Eichhorn, U b Kliem, H C a Kaina, B a Wiessler, M a

a GERMAN CANCER RESEARCH CENTER DKFZ (Germany)

b JOHANNES GUTENBERG UNIVERSITY (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

6 O BENZYLGUANINE; 6 O METHYLGUANINE DNA METHYLTRANSFERASE INHIBITOR; 8 AZA 6 O BENZYLGUANINE; ANTINEOPLASTIC AGENT; LOMEGUATRIB; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DNA REPAIR; DRUG SYNTHESIS; ENZYME INHIBITION; MOLECULAR DYNAMICS; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION;

CELL-FREE SYSTEM; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; GLUCOSIDES; GUANINE; HELA CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MONOSACCHARIDES; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035935676 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm010006e Document Type: Article

Times cited : (41)

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