Facilitation of displacements at the 6-position of purines by the use of 1,4-diazabicyclo[2.2.2]octane as leaving group

Journal of the Chemical Society - Perkin Transactions 1

Volumn , Issue 3, 1997, Pages 185-186

  Lembicz, Nicola K ^a   Grant, Sharon ^a   Clegg, William ^a   Griffin, Roger J ^a   Heath, Sarah L ^a   Golding, Bernard T ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33748529352     PISSN: 0300922X     EISSN: None     Source Type: Journal    
DOI: 10.1039/a608207f     Document Type: Article

References (12)

1. A. E. Pegg, M. E. Dolan and R. C. Moschel, Prog. Nucleic Acid Res. Mol. Biol., 1995, 51, 162.
2. M. Y. Chae, M. G. McDougall, M. E. Dolan, K. Swenn, A. E. Pegg and R. C. Moschel, J. Med. Chem., 1994, 37, 342.
3. T. B. H. McMurry, R. S. McElhinney, J. McCormick, R. H. Elder, J. Kelly, O. P. Margison, J. A. Rafferty, A. J. Watson and M. A. Willington, Int. Pat. Appl., WO 94/29312.
4. C. Arris, C. Bleasdale, A. H. Calvert, N. J. Curtin, C. Dalby, B. T. Golding, R. J. Griffin, J. M. Lunn, G. N. Major and D. R. Newell, Anti-cancer Drug Des., 1994, 9, 401.
5. L. R. Lewis, F. H. Schneider and R. K. Robins, J. Org. Chem., 1961, 26, 3837.
6. J. Kiburis and J. H. Lister, J. Chem. Soc. (C), 1971, 3942.
7. B. L. Gaffney and R. A. Jones, Tetrahedron Lett., 1982, 23, 2253.
8. M. Ashwell, C. Bleasdale, B. T. Golding and I. K. O'Neill, J. Chem. Soc., Chem. Commun., 1990. 955.
9. J. Kiburis and J. H. Lister, J. Chem. Soc. (C), 1971, 1587.
10. H. J. Koeners, A. J. de Kok, C. Romers and J. H. van Boom, Recl. J. R. Neth. Chem. Soc., 1980, 99, 355.
11. S. D. Ross, J. J. Bruno and R. C. Peterson, J. Am. Chem. Soc., 1963, 85, 3999.
12. J. R. Gandler, I. U. Setiarahardjo, C. Tufon and C. Chen, J. Org. Chem., 1992, 57, 4169.