Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a

Journal of Biological Chemistry

Volumn 279, Issue 26, 2004, Pages 27187-27193

  Ray, Soma S ^a   Swanson, Hollie I ^a  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGENS; PROTEINS; TOXIC MATERIALS; TUMORS;

LIGAND ACTIVATED TRANSCRIPTION FACTORS; TUMORIGENESIS;

BIOCHEMISTRY;

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; DIOXIN; HELIX LOOP HELIX PROTEIN; PROTEIN P16; PROTEIN P53; PROTEIN PAS; TRANSCRIPTION FACTOR; TUMOR PROMOTER; UNCLASSIFIED DRUG;

ARTICLE; CANCER; CANCER INHIBITION; CARCINOGENESIS; CELL FATE; CELL IMMORTALIZATION; CELL LINE; GENE SILENCING; HUMAN; HUMAN CELL; KERATINOCYTE; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; SENESCENCE; TRANSCRIPTION REGULATION;

ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; BENZOQUINONES; CELL AGING; CELL LINE, TRANSFORMED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA; DNA METHYLATION; DNA-BINDING PROTEINS; DOWN-REGULATION; FLAVONOIDS; GENE SILENCING; HUMANS; KERATINOCYTES; LACTAMS, MACROCYCLIC; PROMOTER REGIONS (GENETICS); QUINONES; RECEPTORS, ARYL HYDROCARBON; RNA, SMALL INTERFERING; TETRACHLORODIBENZODIOXIN; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 3042695024     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402771200     Document Type: Article

References (38)

1. Kaiser, J. (2000) Science 288, 1941-1944
2. Kaiser, J. (2000) Science 290, 1071
3. Starr, T. B. (2003) Environ. Health Perspect. 111, 1443-1447
4. Schmidt, C. W. (2004) Environ. Health Perspect. 112, A40-A43
5. Edelman, P., Osterloh, J., Pirkle, J., Caudill, S. P., Grainger, J., Jones, R., Blount, B., Calafat, A., Turner, W., Feldman, D., Baron, S., Bernard, B., Lushniak, B. D., Kelly, K., and Prezant, D. (2003) Environ. Health Perspect. 111, 1906-1911
6. Gu, Y. Z., Hogenesch, J. B., and Bradfield, C. A. (2000) Annu. Rev. Pharmacol. Toxicol. 40, 519-561
7. Elizondo, G., Fernandez-Salguero, P., Sheikh, M. S., Kim, G. Y., Fornace, A. J., Lee, K. S., and Gonzalez, F. J. (2000) Mol. Pharmacol. 57, 1056-1063
8. Puga, A., Marlowe, J., Barnes, S., Chang, C. Y., Maier, A., Tan, Z., Kerzee, J. K., Chang, X., Strobeck, M., and Knudsen, E. S. (2002) Toxicology 181-182, 171-177
9. Pelicci, P. G. (2004) J. Clin. Invest. 113, 4-7
10. Ishikawa, F. (2003) Cancer Sci. 94, 944-947
11. Sharpless, N. E., and DePinho, R. A. (2004) J. Clin. Invest. 113, 160-168
12. Hanahan, D., and Weinberg, R. A. (2000) Cell 100, 57-70
13. Herman, J. G., Merlo, A., Mao, L., Lapidus, R. G., Issa, J. P., Davidson, N. E., Sidransky, D., and Baylin, S. B. (1995) Cancer Res. 55, 4525-4530
14. Beausejour, C. M., Krtolica, A., Galimi, F., Narita, M., Lowe, S. W., Yaswen, P., and Campisi, J. (2003) EMBO J. 22, 4212-4222
15. Esteller, M., and Herman, J. G. (2002) J. Pathol. 196, 1-7
16. Levine, A. J. (1997) Cell 88, 323-331
17. Schmitt, C. A., Fridman, J. S., Yang, M., Lee, S., Baranov, E., Hoffman, R. M., and Lowe, S. W. (2002) Cell 109, 335-346
18. Ray, S. S., and Swanson, H. I. (2003) Toxicol. Appl. Pharmacol. 192, 131-145
19. Alani, R. M., Hasskarl, J., Grace, M., Hernandez, M. C., Israel, M. A., and Munger, K. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 9637-9641
20. Swanson, H. I., and Yang, J. (1996) J. Biol. Chem. 271, 31657-31665
21. Henry, E. C., Kende, A. S., Rucci, G., Totleben, M. J., Willey, J. J., Dertinger, S. D., Pollenz, R. S., Jones, J. P., and Gasiewicz, T. A. (1999) Mol. Pharmacol. 55, 716-725
22. Dimri, G. P., Lee, X., Basile, G., Acosta, M., Scott, G., Roskelley, C., Medrano, E. E., Linskens, M., Rubelj, I., and Pereira-Smith, O. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 9363-9367
23. Campisi, J. (2003) Nat. Rev. Cancer 3, 339-349
24. Swanson, H. I., Chan, W. K., and Bradfield, C. A. (1995) J. Biol. Chem. 270, 26292-26302
25. Ma, Q., and Baldwin, K. T. (2000) J. Biol. Chem. 275, 8432-8438
26. Grenert, J. P., Sullivan, W. P., Fadden, P., Haystead, T. A., Clark, J., Mimnaugh, E., Krutzsch, H., Ochel, H. J., Schulte, T. W., Sausville, E., Neckers, L. M., and Toft, D. O. (1997) J. Biol. Chem. 272, 23843-23850
27. Song, Z., and Pollenz, R. S. (2002) Mol. Pharmacol. 62, 806-816
28. Song, Z., and Pollenz, R. S. (2003) Mol. Pharmacol. 63, 597-606
29. Elferink, C. J., and Reiners, J. J., Jr. (1996) BioTechniques 20, 470-477
30. Swanson, H. I., Kraner, S. D., Ray, S. S., Hoagland, M., Thompson, E. D., Zheng, X., and Tian, Y. (2004) Molecular Methods and Mechanisms (Lash, L., ed) Humana Press, Totowa, NJ, in press
31. Reisman, D., Greenberg, M., and Rotter, V. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 5146-5150
32. Esteller, M. (2002) Oncogene 21, 5427-5440
33. Agirre, X., Vizmanos, J. L., Calasanz, M. J., Garcia-Delgado, M., Larrayoz, M. J., and Novo, F. J. (2003) Oncogene 22, 1070-1072
34. Juttermann, R., Li, E., and Jaenisch, R. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 11797-11801
35. Kubota, T., Das, S., Christian, S. L., Baylin, S. B., Herman, J. G., and Ledbetter, D. H. (1997) Nat. Genet. 16, 16-17
36. Dickson, M. A., Hahn, W. C., Ino, Y., Ronfard, V., Wu, J. Y., Weinberg, R. A., Louis, D. N., Li, F. P., and Rheinwald, J. G. (2000) Mol. Cell. Biol. 20, 1436-1447
37. Fernandez-Salgeuro, P. M., Ward, J. M., Sundberg, J. P., and Gonzalez, F. J. (1997) Vet. Pathol. 34, 605-614
38. Suskind, R. R. (1985) Scand. J. Work Environ. Health 11, 165-171