Integrin-dependent amplification of the G2 arrest induced by ionizing radiation

Prostate

Volumn 66, Issue 1, 2006, Pages 88-96

  Kremer, Celeste L ^a   Schmelz, Monika ^b,c   Cress, Anne E ^a,b  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c SOUTHERN ARIZONA VA HEALTH CARE SYSTEM   (United States)

Author keywords

6 4 integrin; Cell cycle; Ionizing radiation; Laminin 5; Phospho cdc2

Indexed keywords

ALPHA6BETA4 INTEGRIN; CELL CYCLE PROTEIN; DNA; KALININ; PROTEIN P53;

ARTICLE; CELL ADHESION; CELL CYCLE G2 PHASE; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; HUMAN; HUMAN CELL; IONIZING RADIATION; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE EPITHELIUM; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; WESTERN BLOTTING;

CELL ADHESION; CELL LINE; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, RADIATION; EPITHELIAL CELLS; G2 PHASE; HUMANS; INTEGRIN ALPHA6BETA4; INTEGRINS; MALE; PROSTATE; RADIATION, IONIZING;

EID: 29344463228     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/pros.20316     Document Type: Article

References (58)

1. Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, Ward E, Feuer EJ, Thun MJ. Cancer statistics. CA Cancer J Clin 2004;54(1):8-29.
2. Oakley-Girvan I, Kolonel LN, Gallagher RP, Wu AH, Felberg A, Whittemore AS. Stage at diagnosis and survival in a multiethnic cohort of prostate cancer patients. Am J Public Health 2003;93(10):1753-1759.
3. Brawer MK. Prostatic intraepithelial neoplasia: A premalignant lesion. Hum Pathol 1992;23(3):242-248.
4. Nagle RB, Hao J, Knox JD, Dalkin BL, Clark V, Cress AE. Expression of hemidesmosomal and extracellular matrix proteins by normal and malignant human prostate tissue. Am J Pathol 1995;146(6):1498-1507.
5. Fuchs ME, Brawer MK, Rennels MA, Nagle RB. The relationship of basement membrane to histologic grade of human prostatic carcinoma. Mod Pathol 1989;2(2):105-111.
6. Cress AE, Rabinovitz I, Zhu W, Nagle RB. The alpha 6 beta 1 and alpha 6 beta 4 integrins in human prostate cancer progression. Cancer Metastasis Rev 1995;14(3):219-228.
7. Davis TL, Cress AE, Dalkin BL, Nagle RB. Unique expression pattern of the alpha6beta4 integrin and laminin-5 in human prostate carcinoma. Prostate 2001;46(3):240-248.
8. Rabinovitz I, Nagle RB, Cress AE. Integrin alpha 6 expression in human prostate carcinoma cells is associated with a migratory and invasive phenotype in vitro and in vivo. Clin Exp Metastasis 1995;13(6):481-491.
9. Witkowski CM, Rabinovitz I, Nagle RB, Affinito KS, Cress AE. Characterization of integrin subunits, cellular adhesion and tumorgenicity of four human prostate cell lines. J Cancer Res Clin Oncol 1993;119(11):637-644.
10. Hao J, Yang Y, McDaniel KM, Dalkin BL, Cress AE, Nagle RB. Differential expression of laminin 5 (alpha 3 beta 3 gamma 2) by human malignant and normal prostate. Am J Pathol 1996;149(4):1341-1349.
11. Savoia P, Trusolino L, Pepino E, Cremona O, Marchisio PC. Expression and topography of integrins and basement membrane proteins in epidermal carcinomas: Basal but not squamous cell carcinomas display loss of alpha 6 beta 4 and BM-600/nicein. J Invest Dermatol 1993;101(3):352-358.
12. Bonkhoff H, Stein U, Remberger K. Differential expression of alpha 6 and alpha 2 very late antigen integrins in the normal, hyperplastic, and neoplastic prostate: Simultaneous demonstration of cell surface receptors and their extracellular ligands. Hum Pathol 1993;24(3):243-248.
13. Burgeson RE, Chiquet M, Deutzmann R, Ekblom P, Engel J, Kleinman H, Martin GR, Meneguzzi G, Paulsson M, Sanes J, Sanes J. A new nomenclature for the laminins. Matrix Biol 1994;14(3):209-211.
14. Mercurio AM, Rabinovitz I, Shaw LM. The alpha 6 beta 4 integrin and epithelial cell migration. Curr Opin Cell Biol 2001;13(5):541-545.
15. Nguyen BP, Ren XD, Schwartz MA, Carter WG. Ligation of integrin alpha 3beta 1 by laminin 5 at the wound edge activates Rho-dependent adhesion of leading keratinocytes on collagen. J Biol Chem 2001;276(47):43860-43870.
16. Belkin AM, Stepp MA. Integrins as receptors for laminins. Microsc Res Tech 2000;51(3):280-301.
17. Li L, Okura M, Imamoto A. Focal adhesions require catalytic activity of Src family kinases to mediate integral-matrix adhesion. Mol Cell Biol 2002;22(4):1203-1217.
18. Mercurio AM, Rabinovitz I. Towards a mechanistic understanding of tumor invasion-lessons from the alpha6beta 4 integrin. Semin Cancer Biol 2001;11(2):129-141.
19. Rabinovitz I, Mercurio AM. The integrin alpha 6 beta 4 and the biology of carcinoma. Biochem Cell Biol 1996;74(6):811-821.
20. Colognato H, Yurchenco PD. Form and function: The laminin family of heterotrimers. Dev Dyn 2000;218(2):213-234.
21. Mizushima H, Miyagi Y, Kikkawa Y, Yamanaka N, Yasumitsu H, Misugi K, Miyazaki K. Differential expression of laminin-5/ladsin subunits in human tissues and cancer cell lines and their induction by tumor promoter and growth factors. J Biochem (Tokyo) 1996;120(6):1196-1202.
22. Koshikawa N, Moriyama K, Takamura H, Mizushima H, Nagashima Y, Yanoma S, Miyazaki K. Overexpression of laminin gamma2 chain monomer in invading gastric carcinoma cells. Cancer Res 1999;59(21):5596-5601.
23. Hao J, Jackson L, Calaluce R, McDaniel K, Dalkin BL, Nagle RB. Investigation into the mechanism of the loss of laminin 5 (alpha3beta3gamma2) expression in prostate cancer. Am J Pathol 2001;158(3):1129-1135.
24. Martin KJ, Kwan CP, Nagasaki K, Zhang X, O'Hare MJ, Kaelin CM, Burgeson RE, Pardee AB, Sager R. Down-regulation of laminin-5 in breast carcinoma cells. Mol Med 1998;4(9):602-613.
25. Trzeciak AR, Nyaga SG, Jaruga P, Lohani A, Dizdaroglu M, Evans MK. Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145. Carcinogenesis 2004;25(8):1359-1370.
26. Malins DC, Johnson PM, Wheeler TM, Barker EA, Polissar NL, Vinson MA. Age-related radical-induced DNA damage is linked to prostate cancer. Cancer Res 2001;61(16):6025-6028.
27. Bonkhoff H, Stein U, Remberger K. The proliferative function of basal cells in the normal and hyperplastic human prostate. Prostate 1994;24(3):114-118.
28. Bartkova J, Horejsi Z, Koed K, Kramer A, Tort F, Zieger K, Guldberg P, Sehested M, Nesland JM, Lukas C, Orntoft T, Lukas J, Bartek J. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 2005;434(7035):864-870.
29. Fan R, Kumaravel TS, Jalali F, Marrano P, Squire JA, Bristow RG. Defective DNA strand break repair after DNA damage in prostate cancer cells: Implications for genetic instability and prostate cancer progression. Cancer Res 2004;64(23):8526-8533.
30. Wang JY, Ho T, Trojanek J, Chintapalli J, Grabacka M, Stoklosa T, Garcia FU, Skorski T, Reiss K. Impaired homologous recombination DNA repair and enhanced sensitivity to DNA damage in prostate cancer cells exposed to anchorage-independence. Oncogene 2005.
31. Assoian RK, Schwartz MA. Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G(1) phase cell-cycle progression. Curr Opin Genet Dev 2001;11(1):48-53.
32. Schwartz MA, Assoian RK. Integrins and cell proliferation: Regulation of cyclin-dependent kinases via cytoplasmic signaling pathways. J Cell Sci 2001;114(Pt 14):2553-2560.
33. Welsh CF, Roovers K, Villanueva J, Liu YQ, Schwartz MA, Assoian RK. Timing of cyclin D1 expression within G1 phase is controlled by Rho. Nat Cell Biol 2001;3(11):950-957.
34. Klekotka PA, Santoro SA, Wang H, Zutter MM. Specific residues within the alpha 2 integrin subunit cytoplasmic domain regulate migration and cell cycle progression via distinct MAPK pathways. J Biol Chem 2001;276(34):32353-32361.
35. Cordes N, van Beuningen D. Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3beta (GSK-3beta) in vitro. Br J Cancer 2003;88(9):1470-1479.
36. Cordes N, Beinke C. Fibronectin alters cell survival and intracellular signaling of confluent A549 cultures after irradiation. Cancer Biol Ther 2004;3(1):47-53.
37. Maity A, McKenna WG, Muschel RJ. The molecular basis for cell cycle delays following ionizing radiation: A review. Radiother Oncol 1994;31(1):1-13.
38. Holgersson A, Heiden T, Castro J, Edgren MR, Lewensohn R, Meijer AE. Different G2/M accumulation in M059J and M059K cells after exposure to DNA double-strand break-inducing agents. Int J Radiat Oncol Biol Phys 2005;61(3):915-921.
39. Rousselle P, Lunstrum GP, Keene DR, Burgeson RE. Kalinin-An epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments. J Cell Biol 1991;114(3):567-576.
40. Smits VA, Medema RH. Checking out the G(2)/M transition. Biochim Biophys Acta 2001;1519(1-2):1-12.
41. Pines J. Four-dimensional control of the cell cycle. Nat Cell Biol 1999;1(3):E73-79.
42. Mettouchi A, Klein S, Guo W, Lopez-Lago M, Lemichez E, Westwick JK, Giancotti FG. Integrin-specific activation of Rac controls progression through the G(1) phase of the cell cycle. Mol Cell 2001;8(1):115-127.
43. Cordes N, Hansmeier B, Beinke C, Meineke V, van Beuningen D. Irradiation differentially affects substratum-dependent survival, adhesion, and invasion of glioblastoma cell lines. Br J Cancer 2003;89(11):2122-2132.
44. Girinsky T, Koumenis C, Graeber TG, Peehl DM, Giaccia AJ. Attenuated response of P53 and P21 in primary cultures of human prostatic epithelial-cells exposed to DNA-damaging agents. Cancer Res 1995;55(17):3726-3731.
45. O'Connell MJ, Walworth NC, Carr AM. The G2-phase DNA-damage checkpoint. Trends Cell Biol 2000;10(7):296-303.
46. Taylor WR, Stark GR. Regulation of the G2/M transition by p53. Oncogene 2001;20(15):1803-1815.
47. Azzam EI, de Toledo SM, Pykett MJ, Nagasawa H, Little JB. CDC2 is down-regulated by ionizing radiation in a p53-dependent manner. Cell Growth Differ 1997;8(11):1161-1169.
48. Huynh H, Nguyen TH, Panasci L, Do P. 2-Chloroethyl-3-sarcosinamide-1- nitrosourea (SarCNU) inhibits prostate carcinoma cell growth via p53-dependent and p53-independent pathways. Cancer 2004;101(12):2881-2891.
49. Wang XW, Zhan Q, Coursen JD, Khan MA, Kontny HU, Yu L, Hollander MC, O'Connor PM, Fornace AJ Jr, Harris CC. GADD45 induction of a G2/M cell cycle checkpoint. Proc Natl Acad Sci USA 1999;96(7):3706-3711.
50. Aplin AE, Hogan BP, Tomeu J, Juliano RL. Cell adhesion differentially regulates the nucleocytoplasmic distribution of active MAP kinases. J Cell Sci 2002;115(Pt 13):2781-2790.
51. Ogawa M, Hiraoka Y, Aiso S. Nuclear translocation of Xenopus laevis paxillin. Biochem Biophys Res Commun 2003;304(4):676-683.
52. Damiano JS, Cress AE, Hazlehurst LA, Shtil AA, Dalton WS. Cell adhesion mediated drug resistance (CAM-DR): Role of integrins and resistance to apoptosis in human myeloma cell lines. Blood 1999;93(5):1658-1667.
53. Frisch SM, Ruoslahti E. Integrins and anoikis. Curr Opin Cell Biol 1997;9(5):701-706.
54. Fornaro M, Plescia J, Chheang S, Tallini G, Zhu YM, King M, Altieri DC, Languino LR. Fibronectin protects prostate cancer cells from tumor necrosis factor alpha-induced apoptosis via the AKT/Survivin pathway. J Biol Chem 2003;278:50402-50411.
55. Yan T, Schupp JE, Hwang HS, Wagner MW, Berry SE, Strickfaden S, Veigl ML, Sedwick WD, Boothman DA, Kinsella TJ. Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation. Cancer Res 2001;61(22):8290-8297.
56. Hudson DL, Guy AT, Fry P, O'Hare MJ, Watt FM, Masters JRW. Epithelial cell differentiation pathways in the human prostate: Identification of intermediate phenotypes by keratin expression. J Histochem Cytochem 2001;49(2):271-278.
57. Bonkhoff H. Role of the basal cells in premalignant changes of the human prostate: A stem cell concept for the development of prostate cancer. Eur Urol 1996;30(2):201-205.
58. Bissell MJ, Labarge MA. Context, tissue plasticity, and cancer: Are tumor stem cells also regulated by the microenvironment? Cancer Cell 2005;7(1):17-23.