메뉴 건너뛰기




Volumn 64, Issue 23, 2004, Pages 8526-8533

Defective DNA strand break repair after DNA damage in prostate cancer cells: Implications for genetic instability and prostate cancer progression

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA; DOUBLE STRANDED DNA; GENE PRODUCT; MITOMYCIN C; PROTEIN; RAD51 PROTEIN; RAD52 PROTEIN; RAD54 PROTEIN;

EID: 9244234509     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-1601     Document Type: Article
Times cited : (104)

References (56)
  • 2
    • 0036480427 scopus 로고    scopus 로고
    • Double-strand breaks and translocations in cancer
    • Elliott B, Jasin M. Double-strand breaks and translocations in cancer. Cell Mol Life Sci 2002;59:373-85.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 373-385
    • Elliott, B.1    Jasin, M.2
  • 3
    • 0035266301 scopus 로고    scopus 로고
    • Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression
    • Pihan GA, Purohit A, Wallace J, Malhotra R, Liotta L, Doxsey SJ. Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression. Cancer Res 2001;61:2212-9.
    • (2001) Cancer Res , vol.61 , pp. 2212-2219
    • Pihan, G.A.1    Purohit, A.2    Wallace, J.3    Malhotra, R.4    Liotta, L.5    Doxsey, S.J.6
  • 4
    • 0037417131 scopus 로고    scopus 로고
    • Evidence of multifocality of telomere erosion in high-grade prostatic intraepithelial neoplasia (HPIN) and concurrent carcinoma
    • Vukovic B, Park PC, Al-Maghrabi J, et al. Evidence of multifocality of telomere erosion in high-grade prostatic intraepithelial neoplasia (HPIN) and concurrent carcinoma. Oncogene 2003;22:1978-87.
    • (2003) Oncogene , vol.22 , pp. 1978-1987
    • Vukovic, B.1    Park, P.C.2    Al-Maghrabi, J.3
  • 5
    • 0036343777 scopus 로고    scopus 로고
    • Expression of different mutant p53 transgenes in neuroblastoma cells leads to different cellular responses to genotoxic agents
    • Gangopadhyay S, Jalali F, Reda D, Peacock J, Bristow RG, Benchimol S. Expression of different mutant p53 transgenes in neuroblastoma cells leads to different cellular responses to genotoxic agents. Exp Cell Res 2002;275:122-31.
    • (2002) Exp Cell Res , vol.275 , pp. 122-131
    • Gangopadhyay, S.1    Jalali, F.2    Reda, D.3    Peacock, J.4    Bristow, R.G.5    Benchimol, S.6
  • 6
    • 0035189448 scopus 로고    scopus 로고
    • ATM - A key determinant of multiple cellular responses to irradiation
    • Kastan MB, Lim DS, Kim ST, Yang D. ATM-a key determinant of multiple cellular responses to irradiation. Acta Oncol 2001;40:686-8.
    • (2001) Acta Oncol , vol.40 , pp. 686-688
    • Kastan, M.B.1    Lim, D.S.2    Kim, S.T.3    Yang, D.4
  • 7
    • 0035736138 scopus 로고    scopus 로고
    • If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells
    • Roninson IB, Broude EV, Chang BD. If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist Updat 2001;4:303-13.
    • (2001) Drug Resist Updat , vol.4 , pp. 303-313
    • Roninson, I.B.1    Broude, E.V.2    Chang, B.D.3
  • 8
    • 0242608423 scopus 로고    scopus 로고
    • Association between polymorphism of human oxoguanine glycosylase 1 and risk of prostate cancer
    • Chen L, Elahi A, Pow-Sang J, Lazarus P, Park J. Association between polymorphism of human oxoguanine glycosylase 1 and risk of prostate cancer. J Urol 2003;170:2471-4.
    • (2003) J Urol , vol.170 , pp. 2471-2474
    • Chen, L.1    Elahi, A.2    Pow-Sang, J.3    Lazarus, P.4    Park, J.5
  • 9
    • 0034816689 scopus 로고    scopus 로고
    • DNA mismatch repair enzyme activity and gene expression in prostate cancer
    • Yeh CC, Lee C, Dahiya R. DNA mismatch repair enzyme activity and gene expression in prostate cancer. Biochem Biophys Res Commun 2001;285:409-13.
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 409-413
    • Yeh, C.C.1    Lee, C.2    Dahiya, R.3
  • 11
    • 0037089533 scopus 로고    scopus 로고
    • Associations between hOGG1 sequence variants and prostate cancer susceptibility
    • Xu J, Zheng SL, Turner A, et al. Associations between hOGG1 sequence variants and prostate cancer susceptibility. Cancer Res 2002;62:2253-7.
    • (2002) Cancer Res , vol.62 , pp. 2253-2257
    • Xu, J.1    Zheng, S.L.2    Turner, A.3
  • 12
    • 0141757494 scopus 로고    scopus 로고
    • Regulation and mechanisms of mammalian double-strand break repair
    • Valerie K, Povirk LF. Regulation and mechanisms of mammalian double-strand break repair. Oncogene 2003;22:5792-812.
    • (2003) Oncogene , vol.22 , pp. 5792-5812
    • Valerie, K.1    Povirk, L.F.2
  • 13
    • 0038700698 scopus 로고    scopus 로고
    • Molecular views of recombination proteins and their control
    • West SC. Molecular views of recombination proteins and their control. Nat Rev Mol Cell Biol 2003;4:435-45.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 435-445
    • West, S.C.1
  • 14
    • 0035083172 scopus 로고    scopus 로고
    • Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs
    • Takata M, Sasaki MS, Tachiiri S, et al. Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs. Mol Cell Biol 2001;21:2858-66.
    • (2001) Mol Cell Biol , vol.21 , pp. 2858-2866
    • Takata, M.1    Sasaki, M.S.2    Tachiiri, S.3
  • 15
    • 1442307845 scopus 로고    scopus 로고
    • Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: A review of the literature
    • Liede A, Karlan BY, Narod SA. Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: a review of the literature. J Clin Oncol 2004;22:735-42.
    • (2004) J Clin Oncol , vol.22 , pp. 735-742
    • Liede, A.1    Karlan, B.Y.2    Narod, S.A.3
  • 16
    • 0037248566 scopus 로고    scopus 로고
    • Cell death in irradiated prostate epithelial cells: Role of apoptotic and clonogenic cell kill
    • Bromfield GP, Meng A, Warde P, Bristow RG. Cell death in irradiated prostate epithelial cells: role of apoptotic and clonogenic cell kill. Prostate Cancer Prostatic Dis 2003;6:73-85.
    • (2003) Prostate Cancer Prostatic Dis , vol.6 , pp. 73-85
    • Bromfield, G.P.1    Meng, A.2    Warde, P.3    Bristow, R.G.4
  • 18
    • 0032499298 scopus 로고    scopus 로고
    • Radioresistant MTp53-expressing rat embryo cell transformants exhibit increased DNA-dsb rejoining during exposure to ionizing radiation
    • Bristow RG, Hu Q, Jang A, et al. Radioresistant MTp53-expressing rat embryo cell transformants exhibit increased DNA-dsb rejoining during exposure to ionizing radiation. Oncogene 1998;16:1789-802.
    • (1998) Oncogene , vol.16 , pp. 1789-1802
    • Bristow, R.G.1    Hu, Q.2    Jang, A.3
  • 19
    • 0036043817 scopus 로고    scopus 로고
    • The comet assay. An overview of techniques
    • Olive PL. The comet assay. An overview of techniques. Methods Mol Biol 2002;203:179-94.
    • (2002) Methods Mol Biol , vol.203 , pp. 179-194
    • Olive, P.L.1
  • 20
    • 0033564523 scopus 로고    scopus 로고
    • Coordinate alterations in the expression of BRCA1, BRCA2, p300, and Rad51 in response to genotoxic and other stresses in human prostate cancer cells
    • Yuan R, Fan S, Wang JA, et al. Coordinate alterations in the expression of BRCA1, BRCA2, p300, and Rad51 in response to genotoxic and other stresses in human prostate cancer cells. Prostate 1999;40:37-49.
    • (1999) Prostate , vol.40 , pp. 37-49
    • Yuan, R.1    Fan, S.2    Wang, J.A.3
  • 22
    • 2342596221 scopus 로고    scopus 로고
    • Recombinational DNA repair in cancer and normal cells: The challenge of functional analysis
    • Willers H, Xia F, Powell SN. Recombinational DNA repair in cancer and normal cells: the challenge of functional analysis. J Biomed Biotechnol 2002;2:86-93.
    • (2002) J Biomed Biotechnol , vol.2 , pp. 86-93
    • Willers, H.1    Xia, F.2    Powell, S.N.3
  • 23
    • 0242268056 scopus 로고    scopus 로고
    • Homologous recombination and cell cycle checkpoints: Rad51 in tumour progression and therapy resistance
    • Henning W, Sturzbecher HW. Homologous recombination and cell cycle checkpoints: Rad51 in tumour progression and therapy resistance. Toxicology 2003;193:91-109.
    • (2003) Toxicology , vol.193 , pp. 91-109
    • Henning, W.1    Sturzbecher, H.W.2
  • 24
    • 0037082151 scopus 로고    scopus 로고
    • Development of a novel rapid assay to assess the fidelity of DNA double-strand-break repair in human tumour cells
    • Collis SJ, Sangar VK, Tighe A, et al. Development of a novel rapid assay to assess the fidelity of DNA double-strand-break repair in human tumour cells. Nucleic Acids Res 2002;30:E1.
    • (2002) Nucleic Acids Res , vol.30
    • Collis, S.J.1    Sangar, V.K.2    Tighe, A.3
  • 25
    • 4344647877 scopus 로고    scopus 로고
    • Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145
    • In press
    • Trzeciak AR, Nyaga SG, Jaruga P, Lohani A, Dizdaroglu M, Evans MK. Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145. Carcinogenesis. In press 2004.
    • (2004) Carcinogenesis
    • Trzeciak, A.R.1    Nyaga, S.G.2    Jaruga, P.3    Lohani, A.4    Dizdaroglu, M.5    Evans, M.K.6
  • 26
    • 0035986839 scopus 로고    scopus 로고
    • Heterogeneity in expression of DNA polymerase beta and DNA repair activity in human tumor cell lines
    • Bhattacharyya N, Chen HC, Wang L, Banerjee S. Heterogeneity in expression of DNA polymerase beta and DNA repair activity in human tumor cell lines. Gene Expr 2002;10:115-23.
    • (2002) Gene Expr , vol.10 , pp. 115-123
    • Bhattacharyya, N.1    Chen, H.C.2    Wang, L.3    Banerjee, S.4
  • 28
    • 0037900683 scopus 로고    scopus 로고
    • Intrinsic presence of poly (ADP-ribose) is significantly increased in malignant prostate compared to benign prostate cell lines
    • McNealy T, Frey M, Trojon L, Knoll T, Alken P, Michel MS. Intrinsic presence of poly (ADP-ribose) is significantly increased in malignant prostate compared to benign prostate cell lines. Anticancer Res 2003;23:1473-8.
    • (2003) Anticancer Res , vol.23 , pp. 1473-1478
    • McNealy, T.1    Frey, M.2    Trojon, L.3    Knoll, T.4    Alken, P.5    Michel, M.S.6
  • 29
    • 0037030467 scopus 로고    scopus 로고
    • Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells
    • Lambert S, Lopez BS. Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells. Oncogene 2002;21:4065-9.
    • (2002) Oncogene , vol.21 , pp. 4065-4069
    • Lambert, S.1    Lopez, B.S.2
  • 31
    • 0037169354 scopus 로고    scopus 로고
    • Cancer susceptibility and the functions of BRCA1 and BRCA2
    • Venkitaraman AR. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 2002;108:171-82.
    • (2002) Cell , vol.108 , pp. 171-182
    • Venkitaraman, A.R.1
  • 32
    • 0142025259 scopus 로고    scopus 로고
    • Interactive competition between homologous recombination and non-homologous end joining
    • Allen C, Halbrook J, Nickoloff JA. Interactive competition between homologous recombination and non-homologous end joining. Mol Cancer Res 2003;1:913-20.
    • (2003) Mol Cancer Res , vol.1 , pp. 913-920
    • Allen, C.1    Halbrook, J.2    Nickoloff, J.A.3
  • 33
    • 0034461607 scopus 로고    scopus 로고
    • Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells
    • Richardson C, Jasin M. Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells. Mol Cell Biol 2000;20:9068-75.
    • (2000) Mol Cell Biol , vol.20 , pp. 9068-9075
    • Richardson, C.1    Jasin, M.2
  • 34
    • 0034677545 scopus 로고    scopus 로고
    • DNA damage-related gene expression as biomarkers to assess cellular response after gamma irradiation of a human lymphoblastoid cell line
    • Bishay K, Ory K, Lebeau J, Levalois C, Olivier MF, Chevillard S. DNA damage-related gene expression as biomarkers to assess cellular response after gamma irradiation of a human lymphoblastoid cell line. Oncogene 2000;19:916-23.
    • (2000) Oncogene , vol.19 , pp. 916-923
    • Bishay, K.1    Ory, K.2    Lebeau, J.3    Levalois, C.4    Olivier, M.F.5    Chevillard, S.6
  • 36
    • 0035504929 scopus 로고    scopus 로고
    • Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells
    • Kim PM, Allen C, Wagener BM, Shen Z, Nickoloff JA. Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells. Nucleic Acids Res 2001;29:4352-60.
    • (2001) Nucleic Acids Res , vol.29 , pp. 4352-4360
    • Kim, P.M.1    Allen, C.2    Wagener, B.M.3    Shen, Z.4    Nickoloff, J.A.5
  • 37
    • 0842329805 scopus 로고    scopus 로고
    • Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability
    • Richardson C, Stark JM, Ommundsen M, Jasin M. Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability. Oncogene 2004;23:546-53.
    • (2004) Oncogene , vol.23 , pp. 546-553
    • Richardson, C.1    Stark, J.M.2    Ommundsen, M.3    Jasin, M.4
  • 38
    • 0032526320 scopus 로고    scopus 로고
    • Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation
    • Vispe S, Cazaux C, Lesca C, Defais M. Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation. Nucleic Acids Res 1998;26:2859-64.
    • (1998) Nucleic Acids Res , vol.26 , pp. 2859-2864
    • Vispe, S.1    Cazaux, C.2    Lesca, C.3    Defais, M.4
  • 39
    • 0345304254 scopus 로고    scopus 로고
    • Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells
    • Bertrand P, Lambert S, Joubert C, Lopez BS. Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells. Oncogene 2003;22:7587-92.
    • (2003) Oncogene , vol.22 , pp. 7587-7592
    • Bertrand, P.1    Lambert, S.2    Joubert, C.3    Lopez, B.S.4
  • 40
    • 0036155849 scopus 로고    scopus 로고
    • Formation of higher-order nuclear Rad51 structures is functionally linked to p21 expression and protection from DNA damage-induced apoptosis
    • Raderschall E, Bazarov A, Cao J, et al. Formation of higher-order nuclear Rad51 structures is functionally linked to p21 expression and protection from DNA damage-induced apoptosis. J Cell Sci 2002;115:153-64.
    • (2002) J Cell Sci , vol.115 , pp. 153-164
    • Raderschall, E.1    Bazarov, A.2    Cao, J.3
  • 41
    • 0031763944 scopus 로고    scopus 로고
    • Increased expression of human DNA repair genes, XRCC1, XRCC3 and RAD51, in radioresistant human KB carcinoma cell line N10
    • Yanagisawa T, Urade M, Yamamoto Y, Furuyama J. Increased expression of human DNA repair genes, XRCC1, XRCC3 and RAD51, in radioresistant human KB carcinoma cell line N10. Oral Oncol 1998;34:524-8.
    • (1998) Oral Oncol , vol.34 , pp. 524-528
    • Yanagisawa, T.1    Urade, M.2    Yamamoto, Y.3    Furuyama, J.4
  • 42
    • 0034109911 scopus 로고    scopus 로고
    • Comparison of DNA repair protein expression and activities between human fibroblast cell lines with different radiosensitivities
    • Carlomagno F, Burnet NG, Turesson I, et al. Comparison of DNA repair protein expression and activities between human fibroblast cell lines with different radiosensitivities. Int J Cancer 2000;85:845-9.
    • (2000) Int J Cancer , vol.85 , pp. 845-849
    • Carlomagno, F.1    Burnet, N.G.2    Turesson, I.3
  • 43
    • 1842432466 scopus 로고    scopus 로고
    • p53 protects from replication-associated DNA double-strand breaks in mammalian cells
    • Kumari A, Schultz N, Helleday T. p53 protects from replication-associated DNA double-strand breaks in mammalian cells. Oncogene 2004;23:2324-9.
    • (2004) Oncogene , vol.23 , pp. 2324-2329
    • Kumari, A.1    Schultz, N.2    Helleday, T.3
  • 44
    • 0034760095 scopus 로고    scopus 로고
    • BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance
    • Slupianek A, Schmutte C, Tombline G, et al. BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance. Mol Cell 2001;8:795-806.
    • (2001) Mol Cell , vol.8 , pp. 795-806
    • Slupianek, A.1    Schmutte, C.2    Tombline, G.3
  • 45
    • 0037049768 scopus 로고    scopus 로고
    • BCR/ABL regulates response to DNA damage: The role in resistance to genotoxic treatment and in genomic instability
    • Skorski T. BCR/ABL regulates response to DNA damage: the role in resistance to genotoxic treatment and in genomic instability. Oncogene 2002;21:8591-604.
    • (2002) Oncogene , vol.21 , pp. 8591-8604
    • Skorski, T.1
  • 46
    • 0034897107 scopus 로고    scopus 로고
    • DNA damage-related RNA expression to assess individual sensitivity to ionizing radiation
    • Bishay K, Dry K, Olivier MF, Lebeau J, Levalois C, Chevillard S. DNA damage-related RNA expression to assess individual sensitivity to ionizing radiation. Carcinogenesis 2001;22:1179-83.
    • (2001) Carcinogenesis , vol.22 , pp. 1179-1183
    • Bishay, K.1    Dry, K.2    Olivier, M.F.3    Lebeau, J.4    Levalois, C.5    Chevillard, S.6
  • 47
    • 0036907407 scopus 로고    scopus 로고
    • Polymorphisms in DNA repair genes and associations with cancer risk
    • Goode EL, Ulrich CM, Potter JD. Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol Biomark Prev 2002;11:1513-30.
    • (2002) Cancer Epidemiol Biomark Prev , vol.11 , pp. 1513-1530
    • Goode, E.L.1    Ulrich, C.M.2    Potter, J.D.3
  • 48
    • 0346457059 scopus 로고    scopus 로고
    • Research into molecular and genetic mechanisms underlying prostate carcinogenesis would be greatly advanced by in vitro prostate cell models
    • Rhim JS. Research into molecular and genetic mechanisms underlying prostate carcinogenesis would be greatly advanced by in vitro prostate cell models. Drugs Today (Barc) 2003;39:837-47.
    • (2003) Drugs Today (Barc) , vol.39 , pp. 837-847
    • Rhim, J.S.1
  • 49
    • 0032837270 scopus 로고    scopus 로고
    • Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA2 loci in breast cancer: Pathological correlations
    • Gonzalez R, Silva JM, Dominguez G, et al. Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA2 loci in breast cancer: pathological correlations. Br J Cancer 1999;81:503-9.
    • (1999) Br J Cancer , vol.81 , pp. 503-509
    • Gonzalez, R.1    Silva, J.M.2    Dominguez, G.3
  • 50
    • 0036772554 scopus 로고    scopus 로고
    • Analysis of mouse Rad54 expression and its implications for homologous recombination
    • Essers J, Hendriks RW, Wesoly J, et al. Analysis of mouse Rad54 expression and its implications for homologous recombination. DNA Repair (Amst) 2002;1:779-93.
    • (2002) DNA Repair (Amst) , vol.1 , pp. 779-793
    • Essers, J.1    Hendriks, R.W.2    Wesoly, J.3
  • 51
    • 4544324453 scopus 로고    scopus 로고
    • Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells
    • Bindra RS, Schaffer PJ, Meng A, et al. Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells. Mol Cell Biol 2004;24:8504-18.
    • (2004) Mol Cell Biol , vol.24 , pp. 8504-8518
    • Bindra, R.S.1    Schaffer, P.J.2    Meng, A.3
  • 52
    • 0347129606 scopus 로고    scopus 로고
    • Selenium: Epidemiology and basic science
    • discussion S53
    • Klein EA. Selenium: epidemiology and basic science. J Urol 2004;171:S50-53; discussion S53.
    • (2004) J Urol , vol.171
    • Klein, E.A.1
  • 53
    • 0242610826 scopus 로고    scopus 로고
    • Gleevec-mediated inhibition of Rad51 expression and enhancement of tumor cell radiosensitivity
    • Russell JS, Brady K, Burgan WE, et al. Gleevec-mediated inhibition of Rad51 expression and enhancement of tumor cell radiosensitivity. Cancer Res 2003;63:7377-83.
    • (2003) Cancer Res , vol.63 , pp. 7377-7383
    • Russell, J.S.1    Brady, K.2    Burgan, W.E.3
  • 54
    • 0035312501 scopus 로고    scopus 로고
    • Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells
    • Collis SJ, Tighe A, Scott SD, Roberts SA, Hendry JH, Margison GP. Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells. Nucleic Acids Res 2001;29:1534-8.
    • (2001) Nucleic Acids Res , vol.29 , pp. 1534-1538
    • Collis, S.J.1    Tighe, A.2    Scott, S.D.3    Roberts, S.A.4    Hendry, J.H.5    Margison, G.P.6
  • 55
    • 2942588660 scopus 로고    scopus 로고
    • siRNA-silencing of DNA repair factors results in enhanced radiation and chemotherapy-mediated killing of human cancer cells
    • Collis S, Swartz M, DeWeese T. siRNA-silencing of DNA repair factors results in enhanced radiation and chemotherapy-mediated killing of human cancer cells. Int J Radiat Oncol Biol Phys 2003;57:S144.
    • (2003) Int J Radiat Oncol Biol Phys , vol.57
    • Collis, S.1    Swartz, M.2    DeWeese, T.3
  • 56
    • 0030583139 scopus 로고    scopus 로고
    • Antisense inhibition of the RAD51 enhances radiosensitivity
    • Taki T, Ohnishi T, Yamamoto A, et al. Antisense inhibition of the RAD51 enhances radiosensitivity. Biochem Biophys Res Commun 1996;223:434-8.
    • (1996) Biochem Biophys Res Commun , vol.223 , pp. 434-438
    • Taki, T.1    Ohnishi, T.2    Yamamoto, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.