Down-regulation of laminin-5 in breast carcinoma cells

Molecular Medicine

Volumn 4, Issue 9, 1998, Pages 602-613

  Martin, Katherine J ^a   Kwan, Chi Pong ^a   Nagasaki, Koichi ^a   Zhang, Xiaohong ^a   O'Hare, Michael J ^b   Kaelin, Carolyn M ^c   Burgeson, Robert E ^a   Pardee, Arthur B ^a   Sager, Ruth ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KALININ; MESSENGER RNA;

ARTICLE; BREAST CARCINOMA; DOWN REGULATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RNA ANALYSIS; SOUTHERN BLOTTING;

EID: 0031756580     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03401760     Document Type: Article

References (60)

1. Burgeson RE, Chiquet M, Deutzman R, et al. (1994) A new nomenclature for the laminins. Matrix Biol. 14:209-211.
2. Carter WG, Kaur P, Gil SG, Gahr PJ, Wayner EA (1990) Distinct functions for integrins α2β1 in focal adhesions and α6β4/bullous pemphigoid antigen in a stable anchoring contact (SAC) of keratinocytes: relation to hemidesmosomes. J. Cell Biol. 111:3141-3145.
3. Wayner EA, Gil SG, Murphy GF, Wilke MS, Carter WG (1993) Epiligrin, a component of epithelial basement membranes, is an adhesive ligand for α3/β1 positive T lymphocytes. J. Cell Biol. 121: 1141-1152.
4. Niessen CM, Hogervorst F, Jaspars LH, et al. (1994) The α6β4 integrin is a receptor for both laminin and kalinin. Exp. Cell Res. 2111:360-367.
5. Gil SG, Brown TA, Ryan MC, Carter WG (1994) Junctional epidermolysis bullosis: defects in expression of epiligrin/nicein/kalinin and integrin beta 4 that inhibit hemidesmosome formation. J. Invest. Dermatol. 103:31S-38S.
6. Rousselle P, Lundstrum GP, Keene DR, Burgeson RE (1991) Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments. J. Biol. Chem. 114: 567-576.
7. Vidal F, Baudoin C, Miquel C, et al. (1995) Cloning of the laminin alpha 3 chain (LAMA3) and identification of a homozygous deletion in a patient with Herlitz junctional epidermolysis bullosa. Genomics 30:273-280.
8. Pulkkinen L, Christiano AM, Gerecke D, Burgeson RE, Pittelkow MR, Uitto J (1994) A homozygous nonsense mutation in the β3 chain gene of laminin 5 (LAMB3) in Herlitz junctional epidermolysis bullosa. Genomics 24:357-360.
9. Aberdam D, Galliano MF, Vailly J, et. al. (1994) Herlitz's junctional epidermolysis bullosa is linked to mutations in the gene (LAMC2) for the γ2 subunit of nicein/kalinin (LAMININ-5). Nat. Genet. 6:299-304.
10. Stahl S, Weitzman S, Jones J (1997) The role of laminin-5 and its receptors in mammary epithelial cell branching morphogenesis. J. Cell Sci. 110:55-63.
11. Gianelli G, Falk-Marzillier J, Schiraldi O, Statler-Stevenson WG, Quaranta V (1997) Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. Science 277:225-228.
12. Miyazaki K, Kikkawa Y, Nakamura A, Yasumitsu H, Umeda M (1993) A large cell-adhesive scatter factor secreted by human gastric carcinoma cells. Proc. Natl. Acad. Sci. U.S.A. 90:11767-11771.
13. Zhang K, Kramer RH (1996) Laminin 5 deposition promotes keratinocyte motility. Exp. Cell Res. 227: 309-322.
14. Tani T, Karttunen T, Kiviluoto T, Kivilaakso E, Burgeson RE, Sipponen P, Virtanen I (1996) Alpha 6 beta 4 integrin and newly deposited laminin-1 and laminin-5 form the adhesion mechanism of gastric carcinoma. Continuous expression of laminins but not that of collagen VII is preserved in invasive parts of the carcinomas: implications for acquisition of the invading phenotype. Am. J. Pathol. 149:781-793.
15. Tani T, Lumme A, Linnala A, et al. (1997) Pancreatic carcinomas deposit laminin-5, preferentially adhere to laminin-5, and migrate on the newly deposited basement membrane. Am. J. Pathol. 151:1289-1302.
16. Gagnoux-Palacios L, Vailly J, Durand-Clement M, Wagner E, Ortonne JP, Meneguzzi G (1996) Functional re-expression of laminin-5 in laminin-5 deficient human keratinocytes modifies cell morphology, motility, and adhesion. J. Biol. Chem. 271:18437-18444.
17. O'Toole EA, Marinkovich MP, Hoeffler WK, Furthmayr H, Woodley DT (1997) Laminin-5 inhibits human keratinocyte migration. Exp. Cell Res. 233:330-339
18. Mizushima H, Miyagi Y, Kikkawa Y, Yamanaka N, Yasumitsu H, Misugi K, Miyazaki K (1996) Differential expression of laminin-5/ladsin subunits in human tissues and cancer cell lines and their induction by tumor promoter and growth factors. J. Biochem. (Tokyo) 120:1196-1202.
19. Kikkawa Y, Umeda M, Miyazaki K (1994) Marked stimulation of cell adhesion and motility by ladsin, a laminin-like scatter factor. J. Biochem. 116:862-869.
20. Goldfinger LE, Stack MS, Jones JCR (1998) Processing of laminin-5 and its functional consequences: role of plasmin and tissue-type plasminogen activator. J. Cell Biol. 141:255-265.
21. Fukushima Y, Ohnishi T, Arita N, Hayakawa T, Sekiguchi K (1998) Integrin alpha3beta1-mediated interaction with laminin-5 stimulates adhesion, migration and invasion of malignant glioma cells. Int. J. Cancer 76:63-72.
22. Pyke C, Romer J, Kallunki P, Lund LR, Ralfkiaer E, Dano K, Tryggvason K (1994) The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers. Am. J. Pathol. 145:782-791.
23. Pyke C, Salo S, Ralfkiaer E, Romer J, Dano K, Tryggvason K (1995) Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon carcinomas. Cancer Res. 55:4132-4139.
24. Bahadoran P, Perrin C, Aberdam D, Spadafora-Pisani A, Meneguzzi G, Ortonne JP (1997) Altered expression of the hemidesmosome-anchoring filament complex proteins in basal cell carcinoma: possible role in the origin of peritumoral lacunae. Br. J. Dermatol. 136:35-42.
25. Chopra A, Maitra B, Korman NJ (1998) Decreased mRNA expression of several basement membrane components in basal cell carcinoma. J. Invest. Dermatol. 110:52-56.
26. Hao J, Yang Y, McDaniel KM, Dalkin BL, Cress ARE, Nagle RB (1996) Differential expression of laminin 5 (alpha 3 beta 3 gamma 2) by human malignant and normal prostate. Am. J. Pathol. 149: 1341-1349.
27. Liang P, Pardee AB (1992) Differential display of eukaryotic messanger RNA by means of the polymerase chain reaction. Science 257:967-971.
28. Sager R (1997) Expression genetics in cancer: Shifting the focus from DNA to RNA. Proc. Natl. Acad. Sci. U.S.A. 94:952-955.
29. Martin KM, Kwan CP, O'Hare MJ, Pardee AB, Sager R (1998) Identification and verification of differential display cDNAs using gene-specific primers and hybridization arrays. Biotechniques 24: 1018-1026.
30. O'Brien W, Stenman G, Sager R (1986) Suppression of tumor growth by senescence in virally transformed human fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 83:8659-8663.
31. Sager R (1991) Senescence as a mode of tumor suppression. Environ. Health Perfect. 93:59-62.
32. INK4a. Cell 88:593-602.
33. Clarke C, Titley J, Davies S, O'Hare MJ (1994) An immunomagnetic separation method using superparamagnetic (MACS) beads for large-scale purification of human mammary luminal and myoepithelial cells. Epithelial Cell Biol. 3:38-46.
34. Band V, Sager R (1989) Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types. Proc. Natl. Acad. Sci. U.S.A. 86:1249-1253.
35. Band V, Zajchowski D, Swisshelm K, et al. (1990) Tumor progression in four mammary epithelial cell lines derived from the same patient. Cancer Res. 50:7351-7357.
36. Zhao S, Ooi SL, Pardee AB (1995) New primer strategy improves the precision of differential display. Biotechniques 18:842-850.
37. Martin KM, Kwan CP, Sager R (1997) A direct-sequencing-based strategy for identifying and cloning cDNAs from differential display gels. In: Liang P, Pardee AB (eds). Methods in Molecular Biology, Differential Display Methods and Protocols. Humana Press, Totowa NJ, pp. 77-85.
38. Chirqwin JM, Przybyla AE, MacDonald RJ, Rutter WJ (1979) Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294.
39. Zajchowski D, Band V, Pauzie N, Tager A, Stampfer MR, Sager R (1988) Expression of growth factors and oncogenes in normal and tumor-derived human mammary epithelial cells. Cancer Res. 48:7041-7047.
40. Marinkovich MP, Lustrum GP, Keene DR, Burgeson RE (1992) The dermis-epidermal junction of human skin contains a novel laminin varient. J. Cell Biol. 119:695-703.
41. Marinkovich MP, Lustrum GP, Burgeson RE (1992) The anchoring filament protein kalinin is synthesized and secreted as a high molecular weight precursor. J. Biol. Chem. 267:17900-17906.
42. Ryan MC, Tizard R, VanDevanter DR, Carter WG (1994) Cloning of the LamA3 gene encoding the α3 chain of the adhesive ligand epiligrin. J. Biol. Chem. 269:22779-22787.
43. Kallunki P, Sainio K, Eddy R, et al. (1992) A truncated laminin chain homologous to the B2 chain: structure, spatial expression, and chromosomal assignment. J. Cell Biol. 119:679-693.
44. Tait L, Soule HD, Russo J (1990) Ultrastructural and immunocytochemical characterization of an immortalized human breast epithelial cell line, MCF-10. Cancer Res. 50:6087-6094.
45. Trask DK, Band V, Zajchowski DA, Yaswen P, Suh T, Sager R (1990) Keratins as markers that distinguish normal and tumor-derived mammary epithelial cells. Proc. Natl. Acad. Sci. U.S.A. 87:2319-2323.
46. Taylor-Papadimitriou J, Berdichevsky F, D'Souza B, Burchell J (1993) Human models of breast cancer. Cancer Surv. 16:59-78.
47. O'Hare MJ, Ormerod MG, Monaghan P, Lane EB, Gusterson BA (1991) Characterization in vitro of luminal and myoepithelial cells isolated from the human mammary gland by cell sorting. Differentiation 46:209-221.
48. Taylor-Papadimitriou J, Stampfer M, Bartek J, Lewis A, Boshell M, Lane EB, Leigh IM (1989) Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: relation to in vivo phenotypes and influence of medium. J. Cell Sci. 94:403-413.
49. Orian-Rousseau V, Aherdam D, Fontao L, Chevalier L, Meneguzzi G, Kedinger M, Simon-Assmann P (1996) Developmental expression of laminin-5 and HD1 in the intestine: epithelial to mesenchymal shift for the laminin gamma-2 chain subunit deposition. Dev. Dyn. 206:12-23.
50. Rudland PS (1993) Epithelial cells and their possible role in the development of the normal and diseased human breast. Histol. Histopathol. 8:385-404.
51. Sager R, Anisowicz A, Neveu M, Liang P, Sotiropoulou G (1993) Identification by differential display of alpha 6 integrin as a candidate tumor suppressor gene. FASEB J. 7:964-970.
52. Natali PG, Nicotra MR, Botti C, Mottolese M, Bitotti A, Segutto D (1992) Changes in expression of α6/β4 integrin heterodimer in primary and metastatic breast cancer. Br. J. Cancer 66:318-322.
53. Koukoulis GK, Howeedy AA, Korhonen M, Virtanen I, Gould VE (1993) Distribution of tenascin, cellular fibronectin and integrin in the normal, hyperplastic and neoplastic breast. J. Submicrosc. Cytol. Pathol. 25:285-295.
54. Howlett AR, Bailey N, Damsky C, Petersen OW, Bissel M (1995) Cellular growth and survival are mediated by β1 integrins in normal human breast but not in breast carcinoma. J. Cell Sci. 108:1945-1957.
55. Sternlicht MD, Barsky SH (1997) The myoepithelial defense: a host defense against cancer. Med. Hypotheses 48:37-46.
56. Sheng S, Carey J, Seftor EA, Dias L, Hendriz MJC, Sager R (1996) Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells. Proc. Natl. Acad. Sci. U.S.A. 93:11669-11674.
57. Airenne T, Haakana H, Sainio K, Kallunki T, Kallunki P, Sariola H, Tryggvason K (1996) Structure of the human laminin gamma 2 chain gene (LAMC2): alternative splicing with different tissue distribution of two transcripts. Genomics 32:54-64.
58. Gerecke DR, Wagman DW, Champliaud MF, Burgeson RE (1994) The complete primary structure for a novel laminin chain, the laminin B1k chain. J. Biol. Chem. 269:11073-11080.
59. Masiakowski P, Breathnach R, Bloch J, Gannon K, Krust A, Chambon P (1982) Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line. Nucl. Acids Res. 10:7895-7903.
60. Goldberg GI, Eisen AZ, Bauer EA (1988) Tissue stress and tumor promotion. Possible relevance to epidermolysis bullosa. Arch. Dermatol. 124:737-741.