Irradiation differentially affects substratum-dependent survival, adhesion, and invasion of glioblastoma cell lines

British Journal of Cancer

Volumn 89, Issue 11, 2003, Pages 2122-2132

  Cordes, N ^a   Hansmeier, B ^a   Beinke, C ^a   Meineke, V ^a   Van Beuningen, D ^a  

^a Bundeswehr Institute of Radiobiology   (Germany)

Author keywords

1 integrin; 3 integrin; Glioblastoma; Invasion; Matrix metalloproteinase 2

Indexed keywords

ANTIBODY; BETA1 INTEGRIN; BETA3 INTEGRIN; BOVINE SERUM ALBUMIN; DISINTEGRIN; ECHISTATIN; FIBRONECTIN; GELATINASE INHIBITOR; INTEGRIN; INTEGRIN ANTIBODY; MATRIGEL; POLYSTYRENE; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTOMA; CANCER CELL CULTURE; CANCER GRADING; CANCER INVASION; CANCER SURVIVAL; CANCER SUSCEPTIBILITY; CELL ADHESION; CELL INVASION; CELL KILLING; CELL STRAIN; CELL STRAIN A 172; CELL STRAIN LN 18; CELL STRAIN LN 229; CELL SURFACE; CELL SURVIVAL; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; GLIOBLASTOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IONIZING RADIATION; IRRADIATION; PRIORITY JOURNAL; RADIATION DOSE; RADIOSENSITIVITY;

ANTIGENS, CD29; CELL ADHESION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; EXTRACELLULAR MATRIX; GLIOBLASTOMA; HUMANS; INTEGRIN BETA3; MATRIX METALLOPROTEINASE 2; NEOPLASM INVASIVENESS; PEPTIDE FRAGMENTS; TUMOR CELLS, CULTURED;

EID: 0348049844     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6601429     Document Type: Article

References (59)

1. Adams JC, Watt FM (1990) Changes in keratinocyte adhesion during terminal differentiation: reduction in fibronectin binding precedes alpha 5 beta 1 integrin loss from the cell surface. Cell 63: 425-435
2. Albelda SM (1993) The role of integrins and other cell adhesion molecules in tumor progression and metastasis. Lab Invest 68: 4-17
3. Assoian RK (1997) Anchorage-dependent cell cycle progression. J Cell Biol 136: 1-4
4. Ballin M, Gomez DE, Sinha CC, Thorgeirsson UP (1988) Ras oncogene mediated induction of a 92-kDa metalloproteinase: strong correlation with the malignant phenotype. Biochem Biophys Res Comm 154: 832-838
5. Bauman GS, Fisher BJ, McDonald W, Amberger VR, Moore E, Del Maestro RF (1999) Effects of radiation on a three-dimensional model of malignant glioma invasion. Int J Dev Neurosci 17: 643-651
6. Bouterfa H, Darlapp AR, Klein E, Pietsch T, Roosen K, Tonn JC (1999) Expression of different extracellular matrix components in human brain tumor and melanoma cells in respect to variant culture conditions. J Neurooncol 44: 23-33
7. Brooks PC, Strömblad S, Sanders LC, von Schalscha TL, Aimes RT, Stetler-Stevenson WG, Quigley JP, Cheresh DA (1996) Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3. Cell 85: 683-693
8. Burger PC, Vogel FS, Green SB, Strike TA (1985) Glioblastoma multiforme and anaplastic astrocytoma: Pathologic criteria and prognostic implications. Cancer 56: 1106-1111
9. Chintala SK, Sawaya R, Gokaslan ZL, Rao JS (1996) Modulation of matrix metalloproteinase-2 and invasion in human glioma cells by alpha3beta1 integrin. Cancer Lett 5: 201-208
10. Chintala SK, Tonn JC, Rao JS (1999) Matrix metalloproteinases and their biological function in human glioma. Int J Dev Neurosci 17: 495-502
11. Corcoran ML, Hewitt RE, Kleiner DE, Stetler-Stevenson WG (1996) MMP-2: expression, activation and inhibition. Enzyme Protein 49: 7-17
12. Cordes N, Blaese MA, Meineke V, van Beuningen D (2002) Ionizing radiation induces up-regulation of functional β1-integrin in lung tumour cell lines in vitro. Int J Radiat Biol 78: 347-357
13. Cordes N, Meineke V (2003) Cell adhesion-mediated radioresistance (CAM-RR): extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro. Strahlenther Onkol 179: 337-344
14. Cordes N, van Beuningen D (2003) Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3β (GSK-3β) in vitro. Br J Cancer 88: 1470-1479
15. Cordes N, Beinke C. Fibronectin alters A549 human lung cancer cell survival after irradiation. Cancer Biol Ther in press
16. Cordes N, Beinke C, Plasswilm L, van Beuningen D. Irradiation and various cytotoxic drugs enhance tyrosine phosphorylation and β1-integrin clustering in human A549 lung cancer cells in a substratum-dependent manner in vitro. Strahlenther Onkol in press (a)
17. Cordes N, Blaese MA, Plasswilm L, Rodemann HP, van Beuningen D (2003) Fibronectin and laminin increase resistance to ionising radiation and the cytotoxic drug Ukrain® in human tumour and normal cells in vitro. Int J Radiat Biol 79: 709-720
18. Elbashir SM, Harborth J, Weber K, Tuchl T (2002) Analysis of gene function in somatic mammalian cells using small interfering RNA. Methods 26: 199-213
19. Ellerbroek SM, Fishman DA, Kearns AS, Bafetti LM, Stack MS (1999) Ovarian carcinoma regulation of matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase through beta1 integrin. Cancer Res 59: 1635-1641
20. Engebraaten O, Schwachenwald R, Valen H, Bjerkvig R, Laerum OD, Backlund EO (1992) Effects of high and low single dose irradiation on glioma spheroid invasion into normal rat brain tissue in vitro. Anticancer Res 12: 1501-1506
21. Ennis BW, Matrisian LM (1994) Matrix degrading metalloproteinases. J Neurooncol 18: 105-109
22. Felding-Habermann B, Cheresh DA (1993) Vitronectin and its receptor. Curr Opin Cell Biol 5: 864-868
23. Fisher BJ, Scott C, Macdonald DR, Coughlin C, Curran WJ (2001) Phase I study of topotecan plus cranial radiation for glioblastoma multiforme: results of Radiation Therapy Oncology Group Trial 9507. J Clin Oncol 19: 1111-1117
24. Friedlander DR, Zagzag D, Shiff B, Cohen H, Allen JC, Kelly PJ, Grumet M (1996) Migration of brain tumor cells on extracellular matrix proteins in vitro correlates with tumor type and grade and involves alphaV and beta1 integrins. Cancer Res 15: 1939-1947
25. Fuks Z, Vlodavsky I, Andreeff M, McLoughlin M, Haimovitz-Friedman A (1992) Effects of extracellular matrix on the response of endothelial cells to radiation in vitro. Eur J Cancer 28: 725-731
26. Galanis E, Buckner J (2000) Chemotherapy for high-grade gliomas. Br J Cancer 82: 1371-1380
27. Giancotti FG, Ruoslahti E (1999) Integrin signaling. Science 285: 1028-1032
28. Gokaslan ZL, Chintala SK, York JE, Boyapati V, Jasti S, Sawaya R, Fuller G, Wildrick DM, Nicolson GL, Rao JS (1998) Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors. Clin Exp Metastasis 16: 721-728
29. Hazlehurst LA, Valkov N, Wisner L, Storey JA, Boulware D, Sullivan DM, Dalton WS (2001) Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells. Blood 98: 1897-1903
30. Hynes RO (2002) Integrins: Bidirectional, allosteric signaling machines. Cell 110: 673-687
31. Kleihues P, Burger PC, Scheithauer BW (1993) The new WHO classification of brain tumours. Brain Pathol 3: 255-268
32. Koivunen E, Arap W, Valtanen H, Rainisalo A, Medina OP, Heikkilä P, Kantor C, Gahmberg CG, Salo T, Konttinen YT, Sorsa T, Ruoslahti E, Pasqualini R (1999) Tumor targeting with a selective gelatinase inhibitor. Nat Biotech 17: 768-774
33. Kristiansen K, Hagen S, Kollevold T, Torvik A, Holme I, Nesbakken R, Hatlevoll R, Lindgren M, Brun A, Lidgren S, Notter G, Andersen AP, Elgen K (1981) Combined modality therapy of operated astrocytomas grade III and IV: confirmation of the value of postoperative irradiation and lack of potentiation of bleomycin on survival time - A prospective multicenter trial of the Scandinavian Glioblastoma Study Group. Cancer 47: 649-652
34. Levin V, Leibel S, Gutin P (1997) Neoplasms of the central nervous system. In Cancer: Principles and Practice of Oncology , DeVita Jr VT, Hellman S, Rosenberg SA (eds) pp 2022-2082. Philadelphia: Lippincott Williams & Wilkins
35. Lewis JM, Truong TN, Schwartz MA (2002) Integrins regulate the apoptotic response to DNA damage through modulation of p53. Proc Natl Acad Sci USA 99: 3627-3632
36. Liotta LA, Stetler-Stevenson WG (1990) Metalloproteinases and cancer invasion. Sem Cancer Biol 1: 99-106
37. Mahesparan R, Read TA, Lund-Johansen M, Skaftnesmo KO, Bjerkvig R, Engebraaten O (2003) Expression of extracellular matrix components in a highly infiltrative in vivo glioma model. Acta Neuropathol (Berl.) 105: 49-57
38. Meredith Jr JE, Fazeli B, Schwartz MA (1993) The extracellular matrix as a cell survival factor. Mol Biol Cell 4: 953-961
39. Mignatti P, Rifkin DB (1996) Plasminogen activators and matrix metalloproteinases in angiogenesis. Enzyme Protein 49: 117-137
40. Montgomery AMP, Reisfeld RA, Cheresh DA (1994) Integrin αvβ3 rescues melanoma cells form apoptosis in three-dimensional dermal collagen. Proc Natl Acad Sci USA 91: 8856-8860
41. Nakano A, Tani E, Miyazaki K, Yamamoto Y, Furuyama J (1995) Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas. J Neurosurg 83: 298-307
42. Nirmala C, Jasti SL, Sawaya R, Kyritsis AP, Konduri SD, Ali-Osman F, Rao JS, Mohanam S (2000) Effects of radiation on the levels of MMP-2, MMP-9 and TIMP-1 during morphogenic glial-endothelial cell interactions. Int J Cancer 88: 766-771
43. Ohnishi T, Hiraga S, Izumoto S, Matsumura H, Kanemura Y, Arita N, Hayakawa T (1998) Role of fibronectin-stimulated tumor cell migration in glioma invasion in vivo: clinical significance of fibronectin and fibronectin receptor expressed in human glioma tissue. Clin Exp Metastasis 16: 729-741
44. Oz B, Karayel FA, Gazio NL, Ozlen F, Balci K (2000) The distribution of extracellular matrix proteins and CD44S expression in human astrocytomas. Pathol Oncol Res 6: 118-124
45. Paulus W, Baur I, Schuppan D, Roggendorf W (1993) Characterization of integrin receptors in normal and neoplastic human brain. Am J Pathol 143: 154-163
46. Rao JS, Steck PA, Mohanam S, Stetler-Stevenson WG, Liotta LA, Sawaya R (1993) Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors. Cancer Res 53: 2208-2211
47. Rich TA, Schiller A, Suit HD, Mankin HJ (1985) Clinical and pathologic review of 48 cases of chondroma. Cancer 56: 182-187
48. Rochefort H (1994) Oestrogens, proteases and breast cancer. From cell lines to clinical applications. Eur J Cancer 30: 1583-1586
49. Rooprai HK, Vanmeter T, Panou C, Schnull S, Trillo-Pazos G, Davies D, Pilkington GJ (1999) The role of integrin receptors in aspects of glioma invasion in vitro. Int J Dev Neurosci 17: 613-623
50. Rose RW, O'Hara MO, Williamson SK, Grant DS (1999) The role of laminin-1 in the modulation of radiation damage in endothelial cells and differentiation. Radiat Res 152: 14-28
51. Ruoslahti E (1992) Control of cell motility and tumor invasion by extracellular matrix interactions. Br J Cancer 66: 239-242
52. Schwartz MA (2001) Integrin signaling revisited. Trends Cell Biol 12: 466-470
53. Schwartz MA, Assoian RK (2001) Integrins and cell proliferation: regulation of cyclin-dependent kinases via cytoplasmic signaling pathways. J Cell Sci 114: 2553-2560
54. Staiano N, Villani GRD, di Martino E, Squillaciota C, Vuotto P, di Natale P (1995) Echistatin inhibits the adhesion of murine melanoma cells to extracellular matrix components. Biochem Mol Biol Int 35: 11-19
55. Stetler-Stevenson WG, Aznavoorain S, Liotta LA (1993) Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu Rev Cell Biol 9: 541-573
56. Stupp R, Dietrich PY, Ostermann Kraljevic S, Pica A, Maillard I, Maeder P, Meuli R, Janzer R, Pizzolato G, Miralbell R, Porchet F, Regli L, de Tribolet N, Mirimanoff RO, Leyvraz S (2002) Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide. J Clin Oncol 20: 1375-1382
57. Troussard AA, Costello P, Yoganathan TN, Kumagai S, Roskelley CD, Dedhar S (2000) The integrin-linked kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9). Oncogene 19: 5444-5452
58. Vlodavsky I, Lui GM, Gospodarowicz D (1980) Morphological appearance, growth behaviour and migratory activity of human tumor cells maintained on extracellular matrix vs plastic. Cell 19: 607-616
59. Wild-Bode C, Weller M, Rimner A, Dichgans J, Wick W (2001) Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma. Cancer Res 61: 2744-2750