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Volumn 2, Issue 6, 2005, Pages 1039-1058

Current advances in sustained-release systems for parenteral drug delivery

Author keywords

Biodegradable polymer; Chemical conjugation; Implant; In situ gelling system; Lipid microparticle; Liposome; Micro and nanoparticulate systems

Indexed keywords

ABARELIX; ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; ANTIHYPERTENSIVE AGENT; ANTINEOPLASTIC AGENT; DRUG CARRIER; HISTRELIN; HUMAN GROWTH HORMONE; IMPANON; INSULIN; LEUPRORELIN; LEVONORGESTREL; LOCAL ANESTHETIC AGENT; MACROGOL; MORPHINE SULFATE; NANOPARTICLE; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; OCTREOTIDE; PACLITAXEL; PEG INTRO; PEGINTERFERON ALPHA2A; PEGINTERFERON ALPHA2B; PEGVISOMANT; POLY(ORTHO ESTER); POLYANHYDRIDE; POLYCAPROLACTONE; POLYGLACTIN; POLYLACTIC ACID; POLYMER; PROTEIN DERIVATIVE; RISPERIDONE; TRIPTORELIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 28244434064     PISSN: 17425247     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425247.2.6.1039     Document Type: Review
Times cited : (123)

References (144)
  • 1
    • 0026603586 scopus 로고
    • Selective tumor localization and improved therapeutic index of anthracylines encapsulated in long-circulating liposomes
    • GABIZON A: Selective tumor localization and improved therapeutic index of anthracylines encapsulated in long-circulating liposomes. Cancer Res. (1992) 52(4):891-896.
    • (1992) Cancer Res. , vol.52 , Issue.4 , pp. 891-896
    • Gabizon, A.1
  • 2
    • 0036310748 scopus 로고    scopus 로고
    • Pharmacokinetics of die carmustine implant
    • FLEMING AB, SALTZMAN WM: Pharmacokinetics of die carmustine implant. Clin. Pharmacokinet. (2002) 41(6):403-419.
    • (2002) Clin. Pharmacokinet. , vol.41 , Issue.6 , pp. 403-419
    • Fleming, A.B.1    Saltzman, W.M.2
  • 3
    • 0037120671 scopus 로고    scopus 로고
    • Polyanhydride implant for antibiotic delivery-from the bench to the clinic
    • LI LC, DENG J, STEPHENS D: Polyanhydride implant for antibiotic delivery-from the bench to the clinic. Adv. Drug Del. Rev. (2002) 54:963-986.
    • (2002) Adv. Drug Del. Rev. , vol.54 , pp. 963-986
    • Li, L.C.1    Deng, J.2    Stephens, D.3
  • 4
    • 2142654898 scopus 로고    scopus 로고
    • Formulation and characterization of paclitaxel, 5-FU and paclitaxel +5-FU microspheres
    • GUPTE A, CIFTCI K: Formulation and characterization of paclitaxel, 5-FU and paclitaxel +5-FU microspheres. Int. J. Pharm. (2004) 276:93-106.
    • (2004) Int. J. Pharm. , vol.276 , pp. 93-106
    • Gupte, A.1    Ciftci, K.2
  • 5
    • 14844337924 scopus 로고    scopus 로고
    • Baclofen-loaded microspheres: Preparation and efficacy testing in a new rabbit model
    • LAGARCE F, RENAUD P, FAISANT N et al.: Baclofen-loaded microspheres: preparation and efficacy testing in a new rabbit model. Eur. J. Pharm. Biapharm. (2005) 59:449-459.
    • (2005) Eur. J. Pharm. Biapharm. , vol.59 , pp. 449-459
    • Lagarce, F.1    Renaud, P.2    Faisant, N.3
  • 6
    • 11844301238 scopus 로고    scopus 로고
    • Gentamicin-loaded discs and microspheres and their modifications: Characterization and in vitro release
    • NARAHARISETTI PK, LEW MD, FU Y-C, LEE D-J, WANG C-H: Gentamicin-loaded discs and microspheres and their modifications: characterization and in vitro release. J. Control. Release (2005) 102:345-359.
    • (2005) J. Control. Release , vol.102 , pp. 345-359
    • Naraharisetti, P.K.1    Lew, M.D.2    Fu, Y.-C.3    Lee, D.-J.4    Wang, C.-H.5
  • 7
    • 24944566791 scopus 로고    scopus 로고
    • Preparation and characterization of melittin-loaded poly-(D,L-lactic acid) of poly(D,L-lactic-co-glycolic acid) microspheres made by the double emulsion method
    • (In press)
    • CUI F, CUN D, TAO A et al.: Preparation and characterization of melittin-loaded poly-(D,L-lactic acid) of poly(D,L-lactic-co-glycolic acid) microspheres made by the double emulsion method. J. Control. Release (2005) (In press).
    • (2005) J. Control. Release
    • Cui, F.1    Cun, D.2    Tao, A.3
  • 8
    • 23144436259 scopus 로고    scopus 로고
    • Evaluation of orntide microspheres in a rat animal model and correlation to in vitro release profiles
    • KOSTANSKI JW, DANI BA, REYNOLDS GA, BOWERS CY, DELUCA PP: Evaluation of orntide microspheres in a rat animal model and correlation to in vitro release profiles. AAPS Pharm. Sci. Tech. (2000) 1(4):E27.
    • (2000) AAPS Pharm. Sci. Tech. , vol.1 , Issue.4
    • Kostanski, J.W.1    Dani, B.A.2    Reynolds, G.A.3    Bowers, C.Y.4    Deluca, P.P.5
  • 9
    • 2142768756 scopus 로고    scopus 로고
    • Importance of single or blended polymer types for controlled in vitro release and plasma levels of a somatostatin analogue entrapped in PLA/PLGA microspheres
    • BLANCO-PRIETO MJ, CAMPANERO MA, BESSEGHIR K, HEIMGATNER F, GANDER B: Importance of single or blended polymer types for controlled in vitro release and plasma levels of a somatostatin analogue entrapped in PLA/PLGA microspheres. J. Control. Release (2004) 96:437-448.
    • (2004) J. Control. Release , vol.96 , pp. 437-448
    • Blanco-Prieto, M.J.1    Campanero, M.A.2    Besseghir, K.3    Heimgatner, F.4    Gander, B.5
  • 10
    • 9244253168 scopus 로고    scopus 로고
    • Biodegradable poly(lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens
    • JIANG W, GUPTA RK, DESHPANDE MC, SCHWENDEMAN SP: Biodegradable poly(lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens. Adv. Drug Del. Rev. (2005) 57:391-410.
    • (2005) Adv. Drug Del. Rev. , vol.57 , pp. 391-410
    • Jiang, W.1    Gupta, R.K.2    Deshpande, M.C.3    Schwendeman, S.P.4
  • 11
    • 0038445582 scopus 로고    scopus 로고
    • Biodegradable microspheres for protein delivery
    • SINHA VR, TREHAN A: Biodegradable microspheres for protein delivery. J. Control. Release (2003) 90:261-280.
    • (2003) J. Control. Release , vol.90 , pp. 261-280
    • Sinha, V.R.1    Trehan, A.2
  • 12
    • 28244476984 scopus 로고    scopus 로고
    • Uniform paclitaxel-loaded biodegradable micropsheres manufactured by ink-jet technology
    • Proceedings of the Winter Symposium and 11th International Symposium on Recent Advances in Drug Delivery Systems Salt Lake City, UT, USA
    • RADULESCU D, SCHWADE N, WAWRO D: Uniform paclitaxel-loaded biodegradable micropsheres manufactured by ink-jet technology. Proceedings of the Winter Symposium and 11th International Symposium on Recent Advances in Drug Delivery Systems, Salt Lake City, UT, USA (2003).
    • (2003)
    • Radulescu, D.1    Schwade, N.2    Wawro, D.3
  • 13
    • 0342762025 scopus 로고    scopus 로고
    • Recombinant human growth hormone poly(lactic-co-glycolic acid) microsphere formulation development
    • CLELAND JL, JOHNSON OL, PUTNEY S, JONES AJ: Recombinant human growth hormone poly(lactic-co-glycolic acid) microsphere formulation development. Adv. Drug Del. Rev. (1997) 28:71-84.
    • (1997) Adv. Drug Del. Rev. , vol.28 , pp. 71-84
    • Cleland, J.L.1    Johnson, O.L.2    Putney, S.3    Jones, A.J.4
  • 14
    • 9644303157 scopus 로고    scopus 로고
    • A new microencapsulation method using an ultrasonic atomizer based on interfacial solvent exchange
    • YEO Y, PARK K: A new microencapsulation method using an ultrasonic atomizer based on interfacial solvent exchange. J. Control. Release (2004) 100(3):379-388.
    • (2004) J. Control. Release , vol.100 , Issue.3 , pp. 379-388
    • Yeo, Y.1    Park, K.2
  • 15
    • 0034756313 scopus 로고    scopus 로고
    • Production of insulin-loaded poly(ethylene glycol)/poly(lactide) (PEG/PLA) nanoparticles by gas antisolvent techniques
    • ELVASSORE A, BERTUCCO A, CALICETI P: Production of insulin-loaded poly(ethylene glycol)/poly(lactide) (PEG/PLA) nanoparticles by gas antisolvent techniques. J. Pharm. Sci. (2001) 90(10):1628-1636.
    • (2001) J. Pharm. Sci. , vol.90 , Issue.10 , pp. 1628-1636
    • Elvassore, A.1    Bertucco, A.2    Caliceti, P.3
  • 17
    • 10044239546 scopus 로고    scopus 로고
    • The production of protein-loaded microparticles by supercritical fluid enhanced mixing and spraying
    • WHITAKER MJ, HAO J, DAVIES OR et al.: The production of protein-loaded microparticles by supercritical fluid enhanced mixing and spraying. J. Control. Release (2005) 101(1-3):85-92.
    • (2005) J. Control. Release , vol.101 , Issue.1-3 , pp. 85-92
    • Whitaker, M.J.1    Hao, J.2    Davies, O.R.3
  • 18
    • 0035819362 scopus 로고    scopus 로고
    • Supercritical fluid mixing: Preparation of thermally sensitive polymer composites containing bioactive materials
    • HOWDLE SM, WATSON MS, WHITAKER MJ et al.: Supercritical fluid mixing: preparation of thermally sensitive polymer composites containing bioactive materials. Chem. Comm. (2001) 1:109-110.
    • (2001) Chem. Comm. , vol.1 , pp. 109-110
    • Howdle, S.M.1    Watson, M.S.2    Whitaker, M.J.3
  • 19
    • 0029901366 scopus 로고    scopus 로고
    • Parenteral protein delivery systems using biodegradable polyesters of ABA block structure, containing hydrophobic poly(lactide-co-glycolide) A blocks and hydrophilic poly(ethylene oxide) B blocks
    • KISSEL T, LI YX, VOLLAND C, GÖRICH S, KONEBERG R: Parenteral protein delivery systems using biodegradable polyesters of ABA block structure, containing hydrophobic poly(lactide-co-glycolide) A blocks and hydrophilic poly(ethylene oxide) B blocks. J. Control. Release (1996) 39(2-3):315-326.
    • (1996) J. Control. Release , vol.39 , Issue.2-3 , pp. 315-326
    • Kissel, T.1    Li, Y.X.2    Volland, C.3    Görich, S.4    Koneberg, R.5
  • 20
    • 0031398520 scopus 로고    scopus 로고
    • Biocompatibility of ABA triblock copolymer microparticles consisting of poly(L-lactic-co-glycolic-acid) A-blocks attached to central poly(oxyethylene) B-blocks in rats after intramuscular injection
    • RONNEBERGER B, KISSEL T, ANDERSON JM: Biocompatibility of ABA triblock copolymer microparticles consisting of poly(L-lactic-co-glycolic-acid) A-blocks attached to central poly(oxyethylene) B-blocks in rats after intramuscular injection. Eur. J. Pharma. Biopharm. (1997) 43(1):19-28.
    • (1997) Eur. J. Pharma. Biopharm. , vol.43 , Issue.1 , pp. 19-28
    • Ronneberger, B.1    Kissel, T.2    Anderson, J.M.3
  • 21
    • 0032484233 scopus 로고    scopus 로고
    • Erythropoietin loaded microspheres prepared from biodegradable LPLG-PEO-LPLG triblock copolymers: Protein stabilization and in vitro release properties
    • MORLOCK M, KISSEL T, LI YX, KOLL H, WINTER G: Erythropoietin loaded microspheres prepared from biodegradable LPLG-PEO-LPLG triblock copolymers: protein stabilization and in vitro release properties. J. Control. Release (1998) 56(1-3):105-115.
    • (1998) J. Control. Release , vol.56 , Issue.1-3 , pp. 105-115
    • Morlock, M.1    Kissel, T.2    Li, Y.X.3    Koll, H.4    Winter, G.5
  • 22
    • 0033985634 scopus 로고    scopus 로고
    • Branched biodegradable polyesters for parenteral drug delivery systems
    • BREITENBACH A, LI YX, KISSEL T: Branched biodegradable polyesters for parenteral drug delivery systems. J. Control. Release (2000) 64(1-3):167-178.
    • (2000) J. Control. Release , vol.64 , Issue.1-3 , pp. 167-178
    • Breitenbach, A.1    Li, Y.X.2    Kissel, T.3
  • 23
    • 0031375429 scopus 로고    scopus 로고
    • Biodegradable brush-like graft polymers from poly(D, L-lactide) or poly(D, L-lactide-co-glycolide) and charge-modified, hydrophilic dextrans as backbone-synthesis, characterization and in vitro degradation properties
    • LI Y, NOTHNAGEL J, KISSEL T: Biodegradable brush-like graft polymers from poly(D, L-lactide) or poly(D, L-lactide-co-glycolide) and charge-modified, hydrophilic dextrans as backbone-synthesis, characterization and in vitro degradation properties. Polymer (1997) 38(25):6197-6206.
    • (1997) Polymer , vol.38 , Issue.25 , pp. 6197-6206
    • Li, Y.1    Nothnagel, J.2    Kissel, T.3
  • 24
    • 20444467972 scopus 로고    scopus 로고
    • Biodistribution properties of nanoparticles based on mixtures of PLGA with PLGA-PEG diblock copolymers
    • BELETSI A, PANAGI Z, AVGOUSTAKIS K: Biodistribution properties of nanoparticles based on mixtures of PLGA with PLGA-PEG diblock copolymers. Int. J. Pharm. (2065) 298(1):233-241.
    • (2065) Int. J. Pharm. , vol.298 , Issue.1 , pp. 233-241
    • Beletsi, A.1    Panagi, Z.2    Avgoustakis, K.3
  • 25
    • 4644354637 scopus 로고    scopus 로고
    • Biodegradable PEGylated microspheres and nanospheres
    • SINHA VR, AGGARWAL A, TREHAN A: Biodegradable PEGylated microspheres and nanospheres. Am. J. Drug Deliv. (2005) 2(3):157-171.
    • (2005) Am. J. Drug Deliv. , vol.2 , Issue.3 , pp. 157-171
    • Sinha, V.R.1    Aggarwal, A.2    Trehan, A.3
  • 27
    • 0037570800 scopus 로고    scopus 로고
    • Potential applications of polymeric microsphere suspension as subcutaneous depot for insulin
    • SHENOY DB, D'SOUZA RJ, TIWARI SB, UDUPA N: Potential applications of polymeric microsphere suspension as subcutaneous depot for insulin. Drug Dev. Ind. Pharm. (2003) 29(5):555-563.
    • (2003) Drug Dev. Ind. Pharm. , vol.29 , Issue.5 , pp. 555-563
    • Shenoy, D.B.1    D'Souza, R.J.2    Tiwari, S.B.3    Udupa, N.4
  • 28
    • 0033959774 scopus 로고    scopus 로고
    • The release of 5-fluorouracil from microspheres for poly(E-caprolactone-co-ethylene oxide)
    • MARTIN LG, COLLETT JH, ATTWOOD D: The release of 5-fluorouracil from microspheres for poly(E-caprolactone-co-ethylene oxide). Drug Dev. Ind. Pharm. (2000) 26(1)7-12.
    • (2000) Drug Dev. Ind. Pharm. , vol.26 , Issue.1 , pp. 7-12
    • Martin, L.G.1    Collett, J.H.2    Attwood, D.3
  • 29
    • 0038384496 scopus 로고    scopus 로고
    • Biodegrdable poly(E-caprolactone)-poly(ethylene glycol) block copolymers: Characterization and their use as drug carriers for a controlled delivery system
    • ZHOU S, DENG X, YANG H: Biodegrdable poly(E-caprolactone)-poly(ethylene glycol) block copolymers: characterization and their use as drug carriers for a controlled delivery system. Biomaterials (2003) 24:3563-3570.
    • (2003) Biomaterials , vol.24 , pp. 3563-3570
    • Zhou, S.1    Deng, X.2    Yang, H.3
  • 30
    • 24344460354 scopus 로고    scopus 로고
    • In vitro degradation and controlled release behavior of D, L-PLGA50 and PCL-b-D,L-PLGA50 copolymer microspheres
    • DONG C-M, GUO Y-Z, QIU K-Y, GU Z-W, FENG X-D: In vitro degradation and controlled release behavior of D, L-PLGA50 and PCL-b-D,L-PLGA50 copolymer microspheres. J. Control. Release (2005) 107:53-64.
    • (2005) J. Control. Release , vol.107 , pp. 53-64
    • Dong, C.-M.1    Guo, Y.-Z.2    Qiu, K.-Y.3    Gu, Z.-W.4    Feng, X.-D.5
  • 31
    • 0033375310 scopus 로고    scopus 로고
    • Enhanced efficacy of a novel controlled release paclitaxel formulation (PACLIMER delivery system) for local-regional therapy of lung cancer tumor nodules in mice
    • HARPER E, DANG W, LAPIDUS RG, ROBERT I, GARVER J: Enhanced efficacy of a novel controlled release paclitaxel formulation (PACLIMER delivery system) for local-regional therapy of lung cancer tumor nodules in mice. Clin. Cancer Res. (1999) 5:4242-4248.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 4242-4248
    • Harper, E.1    Dang, W.2    Lapidus, R.G.3    Robert, I.4    Garver, J.5
  • 32
    • 0036017399 scopus 로고    scopus 로고
    • Polyphosphoester microspheres for sustained release of biologically active nerve growth factor
    • XU X, YU H, GAO S et al.: Polyphosphoester microspheres for sustained release of biologically active nerve growth factor. Biomaterials (2002) 23(17):3765-3772.
    • (2002) Biomaterials , vol.23 , Issue.17 , pp. 3765-3772
    • Xu, X.1    Yu, H.2    Gao, S.3
  • 33
    • 0035955205 scopus 로고    scopus 로고
    • A novel biodegradable gene carrier based on polyphosphoester
    • WANG J, MAO H-Q, LEONG KW: A novel biodegradable gene carrier based on polyphosphoester. J. Am. Chem. Soc. (2001) 123:9480-9481.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 9480-9481
    • Wang, J.1    Mao, H.-Q.2    Leong, K.W.3
  • 34
    • 0041333077 scopus 로고    scopus 로고
    • Polilactofate microspheres for paclitaxel delivery to central nervous system malignancies
    • LI KW, DANG W, TYLER BM et al.: Polilactofate microspheres for paclitaxel delivery to central nervous system malignancies. Clin. Cancer Res. (2003) 9:3441-3447.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 3441-3447
    • Li, K.W.1    Dang, W.2    Tyler, B.M.3
  • 38
    • 0033995750 scopus 로고    scopus 로고
    • Development of a poly(ortho ester) prototype with a latent acid in the polymer backbone for 5-fluorouracil delivery
    • NG SY, SHEN HR, LOPEZ E et al.: Development of a poly(ortho ester) prototype with a latent acid in the polymer backbone for 5-fluorouracil delivery. J. Control. Release (2000) 65:367-374.
    • (2000) J. Control. Release , vol.65 , pp. 367-374
    • Ng, S.Y.1    Shen, H.R.2    Lopez, E.3
  • 40
    • 0037235331 scopus 로고    scopus 로고
    • In vitro characterization of polyorthoester microparticles containing bupivacaine
    • DENG J-S, LI L, TIAN Y et al.: In vitro characterization of polyorthoester microparticles containing bupivacaine. Pharm. Develop. Technol. (2003) 8(1):31-38.
    • (2003) Pharm. Develop. Technol. , vol.8 , Issue.1 , pp. 31-38
    • Deng, J.-S.1    Li, L.2    Tian, Y.3
  • 41
    • 0035816062 scopus 로고    scopus 로고
    • Effect of polymer compositions on the fabrication of poly(ortho-ester) microspheres for controlled release of protein
    • BAI X-L, YANG Y-Y, CHUNG T-S, NG S, HELLER J: Effect of polymer compositions on the fabrication of poly(ortho-ester) microspheres for controlled release of protein. J. Appli. Polymer Sci (2001) 80(10):1630-1642.
    • (2001) J. Appli. Polymer Sci. , vol.80 , Issue.10 , pp. 1630-1642
    • Bai, X.-L.1    Yang, Y.-Y.2    Chung, T.-S.3    Ng, S.4    Heller, J.5
  • 42
    • 1442310888 scopus 로고    scopus 로고
    • Development of novel 5-FU-loaded poly(methylidene malonate 2.1.2)-based microspheres for the treatment of brain cancers
    • FOURNIER E, PASSIRANI C, COLIN N et al.: Development of novel 5-FU-loaded poly(methylidene malonate 2.1.2)-based microspheres for the treatment of brain cancers. Eur. J. Pharm. Biopharm. (2004) 57(2):189-197.
    • (2004) Eur. J. Pharm. Biopharm. , vol.57 , Issue.2 , pp. 189-197
    • Fournier, E.1    Passirani, C.2    Colin, N.3
  • 43
    • 0035838327 scopus 로고    scopus 로고
    • POE-PEG-POE triblock copolymeric microspheres containing protein: I. Preparation and characterization
    • YANG Y-Y, WAN J-P, CHUNG T-S et al.: POE-PEG-POE triblock copolymeric microspheres containing protein: I. Preparation and characterization. J. Control. Release (2001) 75(1-2):115-128.
    • (2001) J. Control. Release , vol.75 , Issue.1-2 , pp. 115-128
    • Yang, Y.-Y.1    Wan, J.-P.2    Chung, T.-S.3
  • 44
    • 0035920771 scopus 로고    scopus 로고
    • Poly(ethylene oxide)/poly(butylenes teraphthalate) segmented block copolymers: The effect of copolymer composition on physical properties and degradation behavior
    • DESCHAMPS AA, GRIJPMA DW, GEIJEN J: Poly(ethylene oxide)/poly(butylenes teraphthalate) segmented block copolymers: the effect of copolymer composition on physical properties and degradation behavior. Polymer (2001) 42:9335-9345.
    • (2001) Polymer , vol.42 , pp. 9335-9345
    • Deschamps, A.A.1    Grijpma, D.W.2    Geijen, J.3
  • 45
    • 0142258121 scopus 로고    scopus 로고
    • In vivo and in vitro degradation of poly(ether ester) block copolymers based on poly(ethylene glycol) and poly(butylene terephthalate)
    • DESCHAMPS AA, APELDOORN AA, HAYEN H et al.: In vivo and in vitro degradation of poly(ether ester) block copolymers based on poly(ethylene glycol) and poly(butylene terephthalate). Biomaterials (2004) 25(2):247-258.
    • (2004) Biomaterials , vol.25 , Issue.2 , pp. 247-258
    • Deschamps, A.A.1    Apeldoorn, A.A.2    Hayen, H.3
  • 46
    • 0029329236 scopus 로고
    • Histological evaluation of a biodegradable polyactive®/hydroxyapatite membrane
    • JANSEN JA, RUIJTER JE, JANSSEN PT, PAQUAY YG: Histological evaluation of a biodegradable polyactive®/hydroxyapatite membrane. Biomaterials (1995) 16(11):819-827.
    • (1995) Biomaterials , vol.16 , Issue.11 , pp. 819-827
    • Jansen, J.A.1    Ruijter, J.E.2    Janssen, P.T.3    Paquay, Y.G.4
  • 47
    • 0034601241 scopus 로고    scopus 로고
    • Microspheres for protein delivery prepared from amphiphilic multiblock copolymers 2. Modulation of release rate
    • BEZEMER JM, RADERSMA R, GRIJPMA DW et al.: Microspheres for protein delivery prepared from amphiphilic multiblock copolymers 2. Modulation of release rate. J. Control. Release (2000) 67:249-260.
    • (2000) J. Control. Release , vol.67 , pp. 249-260
    • Bezemer, J.M.1    Radersma, R.2    Grijpma, D.W.3
  • 48
    • 0032802033 scopus 로고    scopus 로고
    • Degradable dextran hydrogels: Controlled release of a model protein from cylinders and microspheres
    • FRANSSEN O, VENDERVENNET L, RODERS P, HENNINK WE: Degradable dextran hydrogels: controlled release of a model protein from cylinders and microspheres. J. Control. Release (1999) 60:211-221.
    • (1999) J. Control. Release , vol.60 , pp. 211-221
    • Franssen, O.1    Vendervennet, L.2    Roders, P.3    Hennink, W.E.4
  • 50
    • 10644253492 scopus 로고    scopus 로고
    • Effect of polymerization conditions on the network properties of dex-HEMA microspheres and macro-hydrogels
    • CHUNG JT, VLUGT-WENSINK KDF HENNINK WE, ZHANG Z: Effect of polymerization conditions on the network properties of dex-HEMA microspheres and macro-hydrogels. Int. J. Pharm. (2005) 288:51-61.
    • (2005) Int. J. Pharm. , vol.288 , pp. 51-61
    • Chung, J.T.1    Vlugt-Wensink, K.D.F.2    Hennink, W.E.3    Zhang, Z.4
  • 51
    • 0032856016 scopus 로고    scopus 로고
    • Equilibrium water content of microspheres based on cross-linked dextran
    • STENEKES RJ, HENNINK WE: Equilibrium water content of microspheres based on cross-linked dextran. Int. J. Pharm. (1999) 189:131-135.
    • (1999) Int. J. Pharm. , vol.189 , pp. 131-135
    • Stenekes, R.J.1    Hennink, W.E.2
  • 53
    • 0142248878 scopus 로고    scopus 로고
    • IL-2 loaded dextran microspheres with attractive histocompatibility properties for local IL-2 cancer therapy
    • KOTEN JW, LUYN MJ, CADEE JA et al.: IL-2 loaded dextran microspheres with attractive histocompatibility properties for local IL-2 cancer therapy. Cytokine (2003) 24:57-66.
    • (2003) Cytokine , vol.24 , pp. 57-66
    • Koten, J.W.1    Luyn, M.J.2    Cadee, J.A.3
  • 54
    • 0035372010 scopus 로고    scopus 로고
    • In vitro biocompatibility of biodegradable dextran-based hydrogels tested with human fibroblasts
    • DE GROOT CJ, VAN LUYN MJ, VAN DIJK-WOLTHUIS WN et al.: In vitro biocompatibility of biodegradable dextran-based hydrogels tested with human fibroblasts. Biomaterials (2001) 22(11):1197-1203.
    • (2001) Biomaterials , vol.22 , Issue.11 , pp. 1197-1203
    • De Groot, C.J.1    Van Luyn, M.J.2    Van Dijk-Wolthuis, W.N.3
  • 55
    • 0033568088 scopus 로고    scopus 로고
    • Macromolecular colloids of diblock poly(amino acids) that bind insulin
    • CONSTANCIS A, MEYRUEIX R, BRYSON N et al.: Macromolecular colloids of diblock poly(amino acids) that bind insulin. J. Colloid Interface Sci. (1999) 217(2):357-368.
    • (1999) J. Colloid Interface Sci. , vol.217 , Issue.2 , pp. 357-368
    • Constancis, A.1    Meyrueix, R.2    Bryson, N.3
  • 56
    • 0242664216 scopus 로고    scopus 로고
    • An open-label study of abarelix in men with sympotomatic prostate cancer at risk of treatment with LHRH agonist
    • KOCH M, STEIDLE C, BROSMAN S et al.: An open-label study of abarelix in men with sympotomatic prostate cancer at risk of treatment with LHRH agonist. Urology (2003) 62 (5):877-882.
    • (2003) Urology , vol.62 , Issue.5 , pp. 877-882
    • Koch, M.1    Steidle, C.2    Brosman, S.3
  • 58
    • 0035816204 scopus 로고    scopus 로고
    • Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS
    • MAEDA H, SAWA T, KONNO T: Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS. J. Control. Release (2001) 74:47-61.
    • (2001) J. Control. Release , vol.74 , pp. 47-61
    • Maeda, H.1    Sawa, T.2    Konno, T.3
  • 59
    • 0000920626 scopus 로고
    • Tolerabillity of liposomes in vivo
    • G Gregoriadis (Ed.), CRC Press, Boca Raton, FL, USA
    • STROM G, OUSSOREN C, PEETERS P, BARNHOLZ Y: Tolerabillity of liposomes in vivo. In: Liposome Technology. G Gregoriadis (Ed.), CRC Press, Boca Raton, FL, USA (1993):345-383.
    • (1993) Liposome Technology , pp. 345-383
    • Strom, G.1    Oussoren, C.2    Peeters, P.3    Barnholz, Y.4
  • 60
    • 0032496678 scopus 로고    scopus 로고
    • Controlling liposome blood clearances by surface-grafted polymers
    • WOODLE M: Controlling liposome blood clearances by surface-grafted polymers. Adv. Drug Del. Rev. (1998) 32:139-152.
    • (1998) Adv. Drug Del. Rev. , vol.32 , pp. 139-152
    • Woodle, M.1
  • 62
    • 0042073230 scopus 로고    scopus 로고
    • Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing docetaxel
    • IMMORDINAO ML, BRUSA P, ARPICCO S et al.: Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing docetaxel. J. Control. Release (2003) 91:417-429.
    • (2003) J. Control. Release , vol.91 , pp. 417-429
    • Immordinao, M.L.1    Brusa, P.2    Arpicco, S.3
  • 63
    • 13844298715 scopus 로고    scopus 로고
    • Liposomal vasoactive interstinal peptide
    • SETHI V, ONYUKSEL H, RUBINSTEIN I: Liposomal vasoactive interstinal peptide. Meth. Enzym. (2005) 391:377-395.
    • (2005) Meth. Enzym. , vol.391 , pp. 377-395
    • Sethi, V.1    Onyuksel, H.2    Rubinstein, I.3
  • 64
    • 13844276566 scopus 로고    scopus 로고
    • Lipsomal cytokines in the treatment of infectious diseases and cancer
    • HAGEN TL: Lipsomal cytokines in the treatment of infectious diseases and cancer. Meth. Enzym. (2005) 391:125-145.
    • (2005) Meth. Enzym. , vol.391 , pp. 125-145
    • Hagen, T.L.1
  • 65
    • 0035952340 scopus 로고    scopus 로고
    • Liposomes as sustained release system for human interferon-γ: Biopharmaceutical aspect
    • SLOOTEN ML, BOERMAN O, ROMOREN K et al.: Liposomes as sustained release system for human interferon-γ: biopharmaceutical aspect. Bioch. Biophys. ACTA (2001) 1530:134-145.
    • (2001) Bioch. Biophys. Acta , vol.1530 , pp. 134-145
    • Slooten, M.L.1    Boerman, O.2    Romoren, K.3
  • 66
    • 9244234954 scopus 로고    scopus 로고
    • Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs
    • FELNEROVA D, VIRET JF, GLUCK R, MOSER C: Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs. Curr. Opin. Biotech. (2004) 15:518-529.
    • (2004) Curr. Opin. Biotech. , vol.15 , pp. 518-529
    • Felnerova, D.1    Viret, J.F.2    Gluck, R.3    Moser, C.4
  • 67
    • 13844253696 scopus 로고    scopus 로고
    • Glucuronate-modified, long-circulating liposomes for the delivery of anticancer agents
    • OKU N, NAMBA Y: Glucuronate-modified, long-circulating liposomes for the delivery of anticancer agents. Meth. Enzymol. (2005) 391:145-162.
    • (2005) Meth. Enzymol. , vol.391 , pp. 145-162
    • Oku, N.1    Namba, Y.2
  • 68
    • 0036781811 scopus 로고    scopus 로고
    • Ligand-targeted therapeutics in anticancer therapy
    • ALLEN TM: Ligand-targeted therapeutics in anticancer therapy. Nat. Rev. Cancer (2002) 2:750-764.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 750-764
    • Allen, T.M.1
  • 70
    • 9644268054 scopus 로고    scopus 로고
    • Development and charaterization of a novel Cremophor EL free liposome-based paclitaxel (LEP-ETU) formulation
    • ZHANG JA, ANYARAMBHATLA G, MA L et al.: Development and charaterization of a novel Cremophor EL free liposome-based paclitaxel (LEP-ETU) formulation. Eur. J. Pharm. Biopharm. (2005) 59(1):177-187.
    • (2005) Eur. J. Pharm. Biopharm. , vol.59 , Issue.1 , pp. 177-187
    • Zhang, J.A.1    Anyarambhatla, G.2    Ma, L.3
  • 71
    • 0346392116 scopus 로고    scopus 로고
    • Development and charaterization of a novel liposome-based formulation of SN-38
    • ZHANG JA, XUAN T, PARMAR M et al.: Development and charaterization of a novel liposome-based formulation of SN-38. Int. J. Pharm. (2004) 270(1-2):93-107.
    • (2004) Int. J. Pharm. , vol.270 , Issue.1-2 , pp. 93-107
    • Zhang, J.A.1    Xuan, T.2    Parmar, M.3
  • 72
    • 13844275425 scopus 로고    scopus 로고
    • Preparation, characterization and biological analysis of liposomal formulation of vincristine
    • WATERHOUSE DN, MADDEN TD, CULLIS PR, et al.: Preparation, characterization and biological analysis of liposomal formulation of vincristine. Meth. Enzym. (2005) 391:40-57.
    • (2005) Meth. Enzym. , vol.391 , pp. 40-57
    • Waterhouse, D.N.1    Madden, T.D.2    Cullis, P.R.3
  • 74
    • 0036018133 scopus 로고    scopus 로고
    • A lipid based depot (DepoFoam® technology) for sustained release drug delivery
    • MANTRIPRAGADA S: A lipid based depot (DepoFoam® technology) for sustained release drug delivery. Prog. Lipid Res. (2002) 41(5):392-406.
    • (2002) Prog. Lipid Res. , vol.41 , Issue.5 , pp. 392-406
    • Mantripragada, S.1
  • 75
    • 0033621759 scopus 로고    scopus 로고
    • DepoFoam™ technology: A vehicle for controlled delivery of protein and peptide drugs
    • YE Q, ASHERMAN J, STEVENSON M, BROWNSON E, KATRE NV: DepoFoam™ technology: a vehicle for controlled delivery of protein and peptide drugs. J. Control. Release (2000) 64(1-3):155-166.
    • (2000) J. Control. Release , vol.64 , Issue.1-3 , pp. 155-166
    • Ye, Q.1    Asherman, J.2    Stevenson, M.3    Brownson, E.4    Katre, N.V.5
  • 76
    • 0030866983 scopus 로고    scopus 로고
    • Physicochemical characterization of lipid manoparticles and evaluation of their drug loading capacity and sustained release potential
    • WESTESE K, BUNJAS H, KOCH MH: Physicochemical characterization of lipid manoparticles and evaluation of their drug loading capacity and sustained release potential. J. Control. Release (1997) 48:223-236.
    • (1997) J. Control. Release , vol.48 , pp. 223-236
    • Westese, K.1    Bunjas, H.2    Koch, M.H.3
  • 77
    • 0037472095 scopus 로고    scopus 로고
    • Lipid microparticles as sustained release system for a GnRH antagonist (Antide)
    • DELCURTO MD, CHICCO D, D'ANTONIO M et al.: Lipid microparticles as sustained release system for a GnRH antagonist (Antide). J. Control. Release (2003) 89(2):297-310.
    • (2003) J. Control. Release , vol.89 , Issue.2 , pp. 297-310
    • Delcurto, M.D.1    Chicco, D.2    D'Antonio, M.3
  • 78
    • 18744397211 scopus 로고    scopus 로고
    • Effect of solid state transition on the physical stability of suspensions containing bupivacaine lipid microparticles
    • LI LC, ZHU L, SONG JF et al.: Effect of solid state transition on the physical stability of suspensions containing bupivacaine lipid microparticles. Pharm. Dev. Tech (2005) 10:309-318.
    • (2005) Pharm. Dev. Tech. , vol.10 , pp. 309-318
    • Li, L.C.1    Zhu, L.2    Song, J.F.3
  • 79
    • 0343831483 scopus 로고    scopus 로고
    • Atovaquone nanosuspensions slow excellent therapeutic effect in a new murin model of reactivated toxoplamosis
    • SCHOLER N, KRAUSE K, KAYSER O et al.: Atovaquone nanosuspensions slow excellent therapeutic effect in a new murin model of reactivated toxoplamosis. Atntimicrob. Agents. Chemother. (2001) 45:1771-1779.
    • (2001) Atntimicrob. Agents. Chemother. , vol.45 , pp. 1771-1779
    • Scholer, N.1    Krause, K.2    Kayser, O.3
  • 80
    • 0035821356 scopus 로고    scopus 로고
    • Development and characterization of lipid microparticles as a drug carrier for somatostatin
    • REITHMEIER H, HERRMANN J, GÖPFERICH A: Development and characterization of lipid microparticles as a drug carrier for somatostatin. Int. J. Pharm. (2001) 218(1-2):133-143.
    • (2001) Int. J. Pharm. , vol.218 , Issue.1-2 , pp. 133-143
    • Reithmeier, H.1    Herrmann, J.2    Göpferich, A.3
  • 81
    • 0035850227 scopus 로고    scopus 로고
    • Lipid microparticles as a parenteral controlled release device for peptides
    • REITHMEIER H, HERRMANN J, GÖPFERICH A: Lipid microparticles as a parenteral controlled release device for peptides. J. Control. Release (2001) 73(2-3):339-350.
    • (2001) J. Control. Release , vol.73 , Issue.2-3 , pp. 339-350
    • Reithmeier, H.1    Herrmann, J.2    Göpferich, A.3
  • 82
    • 0034112734 scopus 로고    scopus 로고
    • Characterization of co-polymers of lactic and glycolic acid for supercritical fluid processing
    • ENGWICHT A, GIRRESER U, MÜLLER BW: Characterization of co-polymers of lactic and glycolic acid for supercritical fluid processing. Biomaterials (2000) 21(15):1587-1593.
    • (2000) Biomaterials , vol.21 , Issue.15 , pp. 1587-1593
    • Engwicht, A.1    Girreser, U.2    Müller, B.W.3
  • 83
    • 0037151563 scopus 로고    scopus 로고
    • Microencapsulation of protein particles within lipids using a novel supercritical fluid process
    • SANTOS IR, RICHARD J, PECH B, THIES C, BENOIT JP: Microencapsulation of protein particles within lipids using a novel supercritical fluid process. Int. J. Pharm. (2002) 242(1-2):69-78.
    • (2002) Int. J. Pharm. , vol.242 , Issue.1-2 , pp. 69-78
    • Santos, I.R.1    Richard, J.2    Pech, B.3    Thies, C.4    Benoit, J.P.5
  • 84
    • 3242724894 scopus 로고    scopus 로고
    • Formulation and characterization of bupivacaine lipospheres
    • TOONGSUWAN S, LI LC, ERICKSON BK, CHANG HC: Formulation and characterization of bupivacaine lipospheres. Int. J. Pharm. (2004) 28(1-2):57-65.
    • (2004) Int. J. Pharm. , vol.28 , Issue.1-2 , pp. 57-65
    • Toongsuwan, S.1    Li, L.C.2    Erickson, B.K.3    Chang, H.C.4
  • 85
    • 0016820946 scopus 로고
    • Cochleate lipid cylinders: Formation by fusion of unilamellar lipid vesicles
    • PAPAHADJOPOULOS D, VAIL WJ, JACOBSON K, POST G: Cochleate lipid cylinders: formation by fusion of unilamellar lipid vesicles. Biochim. Biophys. Acta. (1975) 394:483-491.
    • (1975) Biochim. Biophys. Acta , vol.394 , pp. 483-491
    • Papahadjopoulos, D.1    Vail, W.J.2    Jacobson, K.3    Post, G.4
  • 86
    • 13844267381 scopus 로고    scopus 로고
    • Drug delivery by lipid cochleates
    • ZARIF L: Drug delivery by lipid cochleates. Meth. Enzym. (2005) 391:314-329.
    • (2005) Meth. Enzym. , vol.391 , pp. 314-329
    • Zarif, L.1
  • 88
    • 13844295615 scopus 로고    scopus 로고
    • Amphotericin B nonocholeates: From formulation to oral efficacy
    • ZARIF L, PERLIN D: Amphotericin B nonocholeates: from formulation to oral efficacy. Drug Deliv. Tech. (2002) 2(4)
    • (2002) Drug Deliv. Tech. , vol.2 , Issue.4
    • Zarif, L.1    Perlin, D.2
  • 89
    • 0035991636 scopus 로고    scopus 로고
    • Pharmacokinetics and tissue distribution after intravenous administration of a single dose of amphotericin B cochleates, a new lipid-based delivery system
    • SEGARRA I, MOVSHIN DA, ZARIF L: Pharmacokinetics and tissue distribution after intravenous administration of a single dose of amphotericin B cochleates, a new lipid-based delivery system. J. Pharm. Sci. (2002) 91(8):1827-1837.
    • (2002) J. Pharm. Sci. , vol.91 , Issue.8 , pp. 1827-1837
    • Segarra, I.1    Movshin, D.A.2    Zarif, L.3
  • 90
    • 28244438816 scopus 로고    scopus 로고
    • Proteoliposome derived cochleate as novel adjuvant
    • (In press)
    • BRACHO G, LASTRE M, CAMPO JD et al.: Proteoliposome derived cochleate as novel adjuvant. Vaccine (2005) (In press).
    • (2005) Vaccine
    • Bracho, G.1    Lastre, M.2    Campo, J.D.3
  • 92
    • 0347258962 scopus 로고    scopus 로고
    • Cochleate delivery vehicles: Applications to gene therapy
    • GOULD-FOGERITE S, MANNINO RJ: Cochleate delivery vehicles: applications to gene therapy. Drug Del. Tech. (2003) 3(2)
    • (2003) Drug Del. Tech. , vol.3 , Issue.2
    • Gould-Fogerite, S.1    Mannino, R.J.2
  • 94
    • 0141614032 scopus 로고    scopus 로고
    • Sustained release injectable products
    • MARTINI A, LAURIA S: Sustained release injectable products. Am. Pharm. Rev. (2003) 6(3):16-20.
    • (2003) Am. Pharm. Rev. , vol.6 , Issue.3 , pp. 16-20
    • Martini, A.1    Lauria, S.2
  • 95
    • 0345814095 scopus 로고    scopus 로고
    • In situ gelling systems
    • JH Senior et al. (Eds), Interpharm Press, Boca Rota, FL, USA
    • TIPTON AI, DUNN RL: In situ gelling systems. In: Sustained-Release Injectable Products. JH Senior et al. (Eds), Interpharm Press, Boca Rota, FL, USA (2000):241-278.
    • (2000) Sustained-Release Injectable Products , pp. 241-278
    • Tipton, A.I.1    Dunn, R.L.2
  • 96
    • 0037299865 scopus 로고    scopus 로고
    • Eligard: Leuprolide acetate in a novel sustained-release delivery system
    • SARTOR O: Eligard: leuprolide acetate in a novel sustained-release delivery system. Urology (2003) 61(2 Suppl. 1):25-31.
    • (2003) Urology , vol.61 , Issue.2 SUPPL. 1 , pp. 25-31
    • Sartor, O.1
  • 97
    • 0036348297 scopus 로고    scopus 로고
    • Sustained delivery of human growth hormone from a novel gel system: SABER™
    • OKUMU FW, DAO LN, FIELDER PJ et al.: Sustained delivery of human growth hormone from a novel gel system: SABER™. Biomaterials (2002) 23(22):4353-4358.
    • (2002) Biomaterials , vol.23 , Issue.22 , pp. 4353-4358
    • Okumu, F.W.1    Dao, L.N.2    Fielder, P.J.3
  • 98
    • 0035858362 scopus 로고    scopus 로고
    • Biodegradable block copolymers for delivery of proteins and water-insoluble drugs
    • ZENTNER GM, RATHI R, SHIH C et al.: Biodegradable block copolymers for delivery of proteins and water-insoluble drugs. J. Control. Release (2001) 72:203-215.
    • (2001) J. Control. Release , vol.72 , pp. 203-215
    • Zentner, G.M.1    Rathi, R.2    Shih, C.3
  • 99
    • 20444481955 scopus 로고    scopus 로고
    • Inhibition of neointimal hyperplasia in vascular grafts by sustained perivascular delivery of paclitaxel
    • MASAKI T, RATHI R, ZENTNER G et al.: Inhibition of neointimal hyperplasia in vascular grafts by sustained perivascular delivery of paclitaxel. Kidney Int. (2004) 66(5):2061-2069.
    • (2004) Kidney Int. , vol.66 , Issue.5 , pp. 2061-2069
    • Masaki, T.1    Rathi, R.2    Zentner, G.3
  • 100
    • 0346846666 scopus 로고    scopus 로고
    • Controlled release of insulin from injectable biodegradable triblock copolymer depot in ZDF rats
    • CHOI S, KIM SW: Controlled release of insulin from injectable biodegradable triblock copolymer depot in ZDF rats. Pharm. Res. (2003) 20:2008-2010.
    • (2003) Pharm. Res. , vol.20 , pp. 2008-2010
    • Choi, S.1    Kim, S.W.2
  • 101
    • 0034333696 scopus 로고    scopus 로고
    • Novel injectable neutral solutions of chitosan form biodegradable gets in situ
    • CHENITE A, CHAPUT C, WANG D et al.: Novel injectable neutral solutions of chitosan form biodegradable gets in situ. Biomaterials (2000) 21(21):2155-2161.
    • (2000) Biomaterials , vol.21 , Issue.21 , pp. 2155-2161
    • Chenite, A.1    Chaput, C.2    Wang, D.3
  • 102
    • 9644301058 scopus 로고    scopus 로고
    • A novel non-toxic camptothecin formulation for cancer chemotherapy
    • BERRADA M, SERREQI A, DABBARH F et al.: A novel non-toxic camptothecin formulation for cancer chemotherapy. Biomaterials (2005) 26(14):2115-2120.
    • (2005) Biomaterials , vol.26 , Issue.14 , pp. 2115-2120
    • Berrada, M.1    Serreqi, A.2    Dabbarh, F.3
  • 103
    • 0035845756 scopus 로고    scopus 로고
    • Effect of sodium chloride on the gelation temperature, gel strength and bioadhesive forces of poloxamer gels containing diclofenac sodium
    • YONG CS, CHOI JS, QUAN QZ et al.: Effect of sodium chloride on the gelation temperature, gel strength and bioadhesive forces of poloxamer gels containing diclofenac sodium. Int. J. Pharm. (2001) 226(1-2):195-205.
    • (2001) Int. J. Pharm. , vol.226 , Issue.1-2 , pp. 195-205
    • Yong, C.S.1    Choi, J.S.2    Quan, Q.Z.3
  • 104
    • 0141652926 scopus 로고    scopus 로고
    • Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats
    • WASAN KM, SUBRANMANIAN R, KWONG M et al.: Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats. J. Pharmacol. Pharm. Sci. (2003) 6(2):189-197.
    • (2003) J. Pharmacol. Pharm. Sci. , vol.6 , Issue.2 , pp. 189-197
    • Wasan, K.M.1    Subranmanian, R.2    Kwong, M.3
  • 105
    • 0037209905 scopus 로고    scopus 로고
    • A hydrogel prepared by in situ cross-linking of a thiol-containing poly(ethylene glycol)-based copolymer: A new biomaterial for protein drug delivery
    • QIU Q, STEFANOS S, MA J et al.: A hydrogel prepared by in situ cross-linking of a thiol-containing poly(ethylene glycol)-based copolymer: a new biomaterial for protein drug delivery. Biomaterials (2002) 24(1):11-18.
    • (2002) Biomaterials , vol.24 , Issue.1 , pp. 11-18
    • Qiu, Q.1    Stefanos, S.2    Ma, J.3
  • 106
    • 3042723430 scopus 로고    scopus 로고
    • Design of Amin-modified graft polyesters for effective gene delivery using DNA-loaded nanoparticles
    • OSTER CG, WITTMAR M, UNGER F et al.: Design of Amin-modified graft polyesters for effective gene delivery using DNA-loaded nanoparticles. Pharm. Res. (2004) 21(6):927-931.
    • (2004) Pharm. Res. , vol.21 , Issue.6 , pp. 927-931
    • Oster, C.G.1    Wittmar, M.2    Unger, F.3
  • 107
    • 28244492875 scopus 로고    scopus 로고
    • Novel in situ forming implants for bioactive macromolecules based on positively charged nanoparticles: Preparation of insulin-loaded nanoparticles, characterization of depots and investigation of insulin release
    • CRS Annual Meeting, Miami, FL, USA
    • PACKHAUSER C, WITTMAR M, KISSEL T: Novel in situ forming implants for bioactive macromolecules based on positively charged nanoparticles: preparation of insulin-loaded nanoparticles, characterization of depots and investigation of insulin release. CRS Annual Meeting. Miami, FL, USA (2005).
    • (2005)
    • Packhauser, C.1    Wittmar, M.2    Kissel, T.3
  • 108
    • 2142710780 scopus 로고    scopus 로고
    • Injectable semi-solid poly(ortho esters) for the controlled delivery of therapeutic agents: Synthesis and applications
    • HELLER J, BARR J, NG S, SHEN HR: Injectable semi-solid poly(ortho esters) for the controlled delivery of therapeutic agents: synthesis and applications. Drug Del. Technol. (2002) 2(1)
    • (2002) Drug Del. Technol. , vol.2 , Issue.1
    • Heller, J.1    Barr, J.2    Ng, S.3    Shen, H.R.4
  • 109
    • 0032940112 scopus 로고    scopus 로고
    • Preparation and characterization of carmustine loaded polyanhydride wafers for treating brain tumors
    • DOMB AJ, ISRAEL ZH, ELMALAK O: Preparation and characterization of carmustine loaded polyanhydride wafers for treating brain tumors. Pharm. Res. (1999) 16(5):762-765.
    • (1999) Pharm. Res. , vol.16 , Issue.5 , pp. 762-765
    • Domb, A.J.1    Israel, Z.H.2    Elmalak, O.3
  • 110
    • 0031890428 scopus 로고    scopus 로고
    • Efficacy and pharmacokinetics of site-specific cefazolin delivery using biodegradable implants in the prevention of post-operative wound infections
    • ALLABABIDI S, SHAH JC: Efficacy and pharmacokinetics of site-specific cefazolin delivery using biodegradable implants in the prevention of post-operative wound infections. Pharm. Res. (1998) 15(2):325-333.
    • (1998) Pharm. Res. , vol.15 , Issue.2 , pp. 325-333
    • Allababidi, S.1    Shah, J.C.2
  • 111
    • 18044371422 scopus 로고    scopus 로고
    • Local delivery of vancomycin for the prophylaxis of prosthetic device-related infections
    • CHILUKURI DM, SHAH JC: Local delivery of vancomycin for the prophylaxis of prosthetic device-related infections. Pharm. Res. (2005) 22(4):563-572.
    • (2005) Pharm. Res. , vol.22 , Issue.4 , pp. 563-572
    • Chilukuri, D.M.1    Shah, J.C.2
  • 112
    • 0033669363 scopus 로고    scopus 로고
    • Progestin implants
    • CROXATTO HB: Progestin implants. Steroids (2000) 65:681-685.
    • (2000) Steroids , vol.65 , pp. 681-685
    • Croxatto, H.B.1
  • 113
    • 4444279257 scopus 로고    scopus 로고
    • Implantable technology for long-term delivery of nalmefene for treatment of alcoholism
    • COSTANTINI LC, KLEPPNER SR, MCDONOUGH J, AZAR MR, PATEL R: Implantable technology for long-term delivery of nalmefene for treatment of alcoholism. Int. J. Pharm. (2004) 283:35-44.
    • (2004) Int. J. Pharm. , vol.283 , pp. 35-44
    • Costantini, L.C.1    Kleppner, S.R.2    McDonough, J.3    Azar, M.R.4    Patel, R.5
  • 114
    • 21744441382 scopus 로고    scopus 로고
    • Long term controlled delivery of therapeutic agents via an implantable osmotically driven system: The DUROS implant
    • MJ Rathbone et al. (Eds), Marcel Dekker, New York, NY, USA
    • WRIGHT JC, CHESTER AE, SKOWRONSKI RJ, LUCAS C: Long term controlled delivery of therapeutic agents via an implantable osmotically driven system: the DUROS implant. In: Modified-Release Drug Delivery Technology. MJ Rathbone et al. (Eds), Marcel Dekker, New York, NY, USA (2003):657-669.
    • (2003) Modified-Release Drug Delivery Technology , pp. 657-669
    • Wright, J.C.1    Chester, A.E.2    Skowronski, R.J.3    Lucas, C.4
  • 115
    • 0035838322 scopus 로고    scopus 로고
    • An in vivo/in vitro comparison with a leuprolide osmotic implant for the treatment of prostate cancer
    • WRIGHT JC, LEONARD ST, STEVENSON CL et al.: An in vivo/in vitro comparison with a leuprolide osmotic implant for the treatment of prostate cancer. J. Control. Release (2001) 75(1-2):1-10.
    • (2001) J. Control. Release , vol.75 , Issue.1-2 , pp. 1-10
    • Wright, J.C.1    Leonard, S.T.2    Stevenson, C.L.3
  • 116
    • 33746743599 scopus 로고    scopus 로고
    • DUROS osmotic pharmaceutical systems for parenteral and site directed therapy
    • WRIGHT JC, JOHNSON RM, YUM SL: DUROS osmotic pharmaceutical systems for parenteral and site directed therapy. Drug Del. Technol. (2003) 3(1).
    • (2003) Drug Del. Technol. , vol.3 , Issue.1
    • Wright, J.C.1    Johnson, R.M.2    Yum, S.L.3
  • 117
    • 28244471320 scopus 로고    scopus 로고
    • Functionality of osmotically driven, implantable therapeutic systems (DUROS implant): Effects of osmotic pressure and delivery of suspension formulations of peptides and proteins
    • DEHNAD H, BERRY S, FEREIRA P et al.: Functionality of osmotically driven, implantable therapeutic systems (DUROS implant): effects of osmotic pressure and delivery of suspension formulations of peptides and proteins. Proc. Int. Symp. Control. Rel. Bioact. Mater. (2000) 27:1016-1017.
    • (2000) Proc. Int. Symp. Control. Rel. Bioact. Mater. , vol.27 , pp. 1016-1017
    • Dehnad, H.1    Berry, S.2    Fereira, P.3
  • 118
    • 0033883540 scopus 로고    scopus 로고
    • Safety and efficacy of an implantable leuprolide delivery system in patients with advanced prostate cancer
    • FOWLER JE, GOTTESMAN JE, REID CF, ANDRIOLE GL, SOLOWAY M: Safety and efficacy of an implantable leuprolide delivery system in patients with advanced prostate cancer. J. Urology (2000) 164:730-734.
    • (2000) J. Urology , vol.164 , pp. 730-734
    • Fowler, J.E.1    Gottesman, J.E.2    Reid, C.F.3    Andriole, G.L.4    Soloway, M.5
  • 119
    • 3242668019 scopus 로고    scopus 로고
    • Relative analgesic potency of fentanyl and sufentanil during intermediate-term infusions in patients after long-term opioid treatment for chronic pain
    • REYNOLDS L, RAUCK R, WEBSTER L et al.: Relative analgesic potency of fentanyl and sufentanil during intermediate-term infusions in patients after long-term opioid treatment for chronic pain. Pain (2004) 110(1-2):182-188.
    • (2004) Pain , vol.110 , Issue.1-2 , pp. 182-188
    • Reynolds, L.1    Rauck, R.2    Webster, L.3
  • 120
    • 0033953933 scopus 로고    scopus 로고
    • An implant releasing the gonadotropin hormone-releasing hormonte agonist histrelin maintains medical castration for up to 30 months in metastatic prostate cancer
    • CHERTIN B, SPITZ IM, LINDENBERG T et al.: An implant releasing the gonadotropin hormone-releasing hormonte agonist histrelin maintains medical castration for up to 30 months in metastatic prostate cancer. J. Urology (2000) 163(3):838-844.
    • (2000) J. Urology , vol.163 , Issue.3 , pp. 838-844
    • Chertin, B.1    Spitz, I.M.2    Lindenberg, T.3
  • 121
    • 0037428969 scopus 로고    scopus 로고
    • Effective drug delivery by pegylated drug conjugates
    • GREENWALD RB: Effective drug delivery by pegylated drug conjugates. Adv. Drug Del. Rev. (2003) 55:217-250.
    • (2003) Adv. Drug Del. Rev. , vol.55 , pp. 217-250
    • Greenwald, R.B.1
  • 122
    • 0037757532 scopus 로고    scopus 로고
    • Polysialylated insulin: Synthesis, characterization and biological activity in vivo
    • JAIN S, HRECZU-HIRST DH, MCCORMACK B et al.: Polysialylated insulin: synthesis, characterization and biological activity in vivo. Biochim. Biophys. Acta (2003) 1622:42-49.
    • (2003) Biochim. Biophys. Acta , vol.1622 , pp. 42-49
    • Jain, S.1    Hreczu-Hirst, D.H.2    McCormack, B.3
  • 123
    • 0344420226 scopus 로고    scopus 로고
    • Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates
    • CALICETI P, VERONESE FM: Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates. Adv. Drug Del. Rev. (2003) 55:1261-1277.
    • (2003) Adv. Drug Del. Rev. , vol.55 , pp. 1261-1277
    • Caliceti, P.1    Veronese, F.M.2
  • 124
    • 0032967784 scopus 로고    scopus 로고
    • Enhanced antitumor potency of polyethylene glycolylated tumor necrosis factor-α: A novel polymer-conjugation technique with a reversible amino-protective reagent
    • TSUNODA S, ISHIKAWA T, YAMAMOTO Y et al.: Enhanced antitumor potency of polyethylene glycolylated tumor necrosis factor-α: a novel polymer-conjugation technique with a reversible amino-protective reagent. J. Pharmacol. Exp. Ther. (1999) 290:368-372.
    • (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 368-372
    • Tsunoda, S.1    Ishikawa, T.2    Yamamoto, Y.3
  • 125
    • 0035136815 scopus 로고    scopus 로고
    • Selective enhancement of thrombopoietic activity of PEGylated interleukin 6 by a simple procedure using a reversible aminoprotective reagent
    • TSUNODA S, ISHIKAWA T, WATANABE M et al.: Selective enhancement of thrombopoietic activity of PEGylated interleukin 6 by a simple procedure using a reversible aminoprotective reagent. Br. J. Haematology (2001) 112(1):181.
    • (2001) Br. J. Haematology , vol.112 , Issue.1 , pp. 181
    • Tsunoda, S.1    Ishikawa, T.2    Watanabe, M.3
  • 126
    • 0035858379 scopus 로고    scopus 로고
    • Improvements in protein PEGylation: Pegylated interferons for treatment of hepatitis C
    • KOZLOWSKI A, HARRIS MJ: Improvements in protein PEGylation: pegylated interferons for treatment of hepatitis C. J. Control. Release (2001) 72(1-3):217-224.
    • (2001) J. Control. Release , vol.72 , Issue.1-3 , pp. 217-224
    • Kozlowski, A.1    Harris, M.J.2
  • 128
    • 0345283166 scopus 로고    scopus 로고
    • PEGylation of growth hormone-releasing hormone (GRF) analogues
    • ESPOSITO P, BARBERO L, CACCIA P et al.: PEGylation of growth hormone-releasing hormone (GRF) analogues. Adv. Drug Del. Rev. (2003) 55(10):1279-1291.
    • (2003) Adv. Drug Del. Rev. , vol.55 , Issue.10 , pp. 1279-1291
    • Esposito, P.1    Barbero, L.2    Caccia, P.3
  • 129
    • 0345504113 scopus 로고    scopus 로고
    • Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: A comparison of conjugation chemistries and compounds
    • LEE LS, CONOVER C, SHI C, WHITLOW M, FILPULA D: Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: a comparison of conjugation chemistries and compounds. Bioconjug. Chem. (1999) 10:973-981.
    • (1999) Bioconjug. Chem. , vol.10 , pp. 973-981
    • Lee, L.S.1    Conover, C.2    Shi, C.3    Whitlow, M.4    Filpula, D.5
  • 130
    • 0035284411 scopus 로고    scopus 로고
    • Peptide and protein PEGylation: A review of problems and solutions
    • VERONESE FM: Peptide and protein PEGylation: a review of problems and solutions. Biomaterials (2001) 22:405-417.
    • (2001) Biomaterials , vol.22 , pp. 405-417
    • Veronese, F.M.1
  • 131
    • 0035816168 scopus 로고    scopus 로고
    • PEG drugs: An overview
    • GREENWALD RB: PEG drugs: an overview. J. Control. Release (2001) 74:159-171.
    • (2001) J. Control. Release , vol.74 , pp. 159-171
    • Greenwald, R.B.1
  • 132
    • 0345283158 scopus 로고    scopus 로고
    • Clinical development of PEGylated recombinant staphylokinase (PEG-Sak) for bolus thrombolytic treatment of patients with acute myocardial infarction
    • MOREADITH RW, COLLEN D: Clinical development of PEGylated recombinant staphylokinase (PEG-Sak) for bolus thrombolytic treatment of patients with acute myocardial infarction. Adv. Drug Del. Rev. (2003) 55:1337-1345.
    • (2003) Adv. Drug Del. Rev. , vol.55 , pp. 1337-1345
    • Moreadith, R.W.1    Collen, D.2
  • 133
    • 23444455640 scopus 로고    scopus 로고
    • Improving the therapeutic efficacy of peptides and proteins: A role for polysialic acids
    • GREGORIADIS G, JAIN S, PAPAIOANNOU I, LAING P: Improving the therapeutic efficacy of peptides and proteins: A role for polysialic acids. Int. J. Pharm. (2005) 300:125-130.
    • (2005) Int. J. Pharm. , vol.300 , pp. 125-130
    • Gregoriadis, G.1    Jain, S.2    Papaioannou, I.3    Laing, P.4
  • 135
    • 0035901757 scopus 로고    scopus 로고
    • The effect of polysialylation on the immunogenicity and antigenicity of asparaginase: Implications in its pharmacokinetics
    • FERNANDES AI, GREGORIADIS G: The effect of polysialylation on the immunogenicity and antigenicity of asparaginase: implications in its pharmacokinetics. Int. J. Pharm. (2001) 217:215-224.
    • (2001) Int. J. Pharm. , vol.217 , pp. 215-224
    • Fernandes, A.I.1    Gregoriadis, G.2
  • 136
    • 0037757532 scopus 로고    scopus 로고
    • Polysialylated insulin: Synthesis, characterization and biological activiry in vivo
    • JAIN S, HRECZUK-HIRST DH, MCCORMACK B et al.: Polysialylated insulin: synthesis, characterization and biological activiry in vivo. Biochim. Biophys. Acta (2003) 1622:42-49.
    • (2003) Biochim. Biophys. Acta , vol.1622 , pp. 42-49
    • Jain, S.1    Hreczuk-Hirst, D.H.2    McCormack, B.3
  • 138
    • 0037339649 scopus 로고    scopus 로고
    • Development and characterization of a glucagon-like peptide 1-albumin conjugate-the ability to activate the glucagon-like peptide 1 receptor in vivo
    • KIM J-G, BAGGIO L, BRIDON D et al.: Development and characterization of a glucagon-like peptide 1-albumin conjugate-the ability to activate the glucagon-like peptide 1 receptor in vivo. Diabetes (2003) 52:751-759.
    • (2003) Diabetes , vol.52 , pp. 751-759
    • Kim, J.-G.1    Baggio, L.2    Bridon, D.3
  • 139
    • 21244502727 scopus 로고    scopus 로고
    • CJC-1131, a long -acting GLP-1 derivative, exhibits an extended pharmacokinetic profile in healthy human volunteers
    • Annual ADA meeting. San Francisco, CA, USA
    • LAWRENCE B, DREYFUS JF, WEN S et al.: CJC-1131, a long -acting GLP-1 derivative, exhibits an extended pharmacokinetic profile in healthy human volunteers. Annual ADA meeting. San Francisco, CA, USA (2003).
    • (2003)
    • Lawrence, B.1    Dreyfus, J.F.2    Wen, S.3
  • 140
    • 0035818460 scopus 로고    scopus 로고
    • Dextrins as potential carriers for drug targeting: Tailored rates of dextrin degradation by introduction of pendant groups
    • HRECZUK-HIRST D, CHICCO D, GERMAN L, DUNCAN R: Dextrins as potential carriers for drug targeting: tailored rates of dextrin degradation by introduction of pendant groups. Int. J. Pharm. (2001) 230(1-2):57-66.
    • (2001) Int. J. Pharm. , vol.230 , Issue.1-2 , pp. 57-66
    • Hreczuk-Hirst, D.1    Chicco, D.2    German, L.3    Duncan, R.4
  • 141
    • 0024715402 scopus 로고
    • Poly(anhydrides). 3. Poly(anhydrides) based on aliphatic-aromatic diacids
    • DOMB AJ, LANGER R: Poly(anhydrides). 3. Poly(anhydrides) based on aliphatic-aromatic diacids. Macromolecules (1989) 22:3200-3204.
    • (1989) Macromolecules , vol.22 , pp. 3200-3204
    • Domb, A.J.1    Langer, R.2
  • 144
    • 0037123741 scopus 로고    scopus 로고
    • Elongated supramolecular assemblies in drug delivery
    • ZARIF L: Elongated supramolecular assemblies in drug delivery. J. Control. Release (2002) 81:7-23.
    • (2002) J. Control. Release , vol.81 , pp. 7-23
    • Zarif, L.1


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