Local delivery of vancomycin for the prophylaxis of prosthetic device-related infections

Pharmaceutical Research

Volumn 22, Issue 4, 2005, Pages 563-572

  Chilukuri, Dakshina M ^a   Shah, Jaymin C ^b  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b PFIZER INC   (United States)

Author keywords

Antibiotic; Biofilm infection; Efficacy; Glyceryl monostearate; Implants; Local delivery; Pharmacokinetics; Prosthetic device; Surgical wound infection; Vancomycin

Indexed keywords

GLYCEROL STEARATE; VANCOMYCIN;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIUM CULTURE; BACTERIUM IDENTIFICATION; BIOFILM; BLOOD ANALYSIS; BLOOD SAMPLING; BLOOD VESSEL GRAFT; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG IMPLANTATION; DRUG SCREENING; ENTEROCOCCUS FAECALIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; INFECTION PREVENTION; MALE; MICROBIOLOGICAL EXAMINATION; NONHUMAN; PRIORITY JOURNAL; PROSTHESIS; PROSTHESIS INFECTION; PUS; RAT; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STAPHYLOCOCCUS INFECTION; TREATMENT FAILURE;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; DRUG DELIVERY SYSTEMS; DRUG IMPLANTS; GLYCERIDES; IMPLANTS, EXPERIMENTAL; INJECTIONS, INTRAMUSCULAR; PROSTHESIS-RELATED INFECTIONS; RATS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS EPIDERMIDIS; VANCOMYCIN;

EID: 18044371422     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11095-005-2497-7     Document Type: Article

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