-
2
-
-
0000342286
-
Pharmacokinetics of peptide and protein drugs
-
V.H.L. Lee. New York: Marcel Dekker
-
Kompella U.B., Lee V.H.L. Pharmacokinetics of peptide and protein drugs. Lee V.H.L. Peptide and Protein Drug Delivery. 1991;391 Marcel Dekker, New York.
-
(1991)
Peptide and Protein Drug Delivery
, pp. 391
-
-
Kompella, U.B.1
Lee, V.H.L.2
-
3
-
-
0002853565
-
Renal uptake and disposal of proteins and peptides
-
K.L. Audus, & T.J. Raub. New York: Plenum Press
-
Rabkin R., Dahl D.C. Renal uptake and disposal of proteins and peptides. Audus K.L., Raub T.J. Biological Barriers in Protein Delivery. 1993;299 Plenum Press, New York.
-
(1993)
Biological Barriers in Protein Delivery
, pp. 299
-
-
Rabkin, R.1
Dahl, D.C.2
-
4
-
-
17844380498
-
Pegylation: A novel process for modifying pharmacokinetics
-
Harris J.M., Martin N.E., Modi M. Pegylation: a novel process for modifying pharmacokinetics. Clin. Pharmacokinet. 40:2000;539-551.
-
(2000)
Clin. Pharmacokinet.
, vol.40
, pp. 539-551
-
-
Harris, J.M.1
Martin, N.E.2
Modi, M.3
-
6
-
-
0027253357
-
The conjugation of proteins with poly(ethylene glycol) and other polymers
-
Kartre K. The conjugation of proteins with poly(ethylene glycol) and other polymers. Adv. Drug Deliv. Rev. 10:1993;91-114.
-
(1993)
Adv. Drug Deliv. Rev.
, vol.10
, pp. 91-114
-
-
Kartre, K.1
-
7
-
-
0017976656
-
Glomerular permeselectivity: Barrier function based on discrimination of molecular size and charge
-
Brenner B.M., Hostetter T.H., Humes H.D. Glomerular permeselectivity: barrier function based on discrimination of molecular size and charge. Am. J. Physiol. 234:1978;F455-F460.
-
(1978)
Am. J. Physiol.
, vol.234
-
-
Brenner, B.M.1
Hostetter, T.H.2
Humes, H.D.3
-
8
-
-
0018670579
-
Macromolecule transport across glomerular capillaries: Application of pore theory
-
Deen W.M., Bohrer M.P., Brenner B.M. Macromolecule transport across glomerular capillaries: application of pore theory. Kidney Int. 16:1979;353-365.
-
(1979)
Kidney Int.
, vol.16
, pp. 353-365
-
-
Deen, W.M.1
Bohrer, M.P.2
Brenner, B.M.3
-
9
-
-
0035284411
-
Peptide and protein PEGylation: A review of problems and solutions
-
Veronese F.M. Peptide and protein PEGylation: a review of problems and solutions. Biomaterials. 22:2001;405-417.
-
(2001)
Biomaterials
, vol.22
, pp. 405-417
-
-
Veronese, F.M.1
-
11
-
-
0023683508
-
Relationship of effective molecular size to systemic clearance in rats of recombinant interleukin-2 chemically modified with water soluble polymers
-
Knauff M.J., Bell D.P., Hirtzer P., Luo Z.P., Young J.D., Kartre N.V. Relationship of effective molecular size to systemic clearance in rats of recombinant interleukin-2 chemically modified with water soluble polymers. J. Biol. Chem. 263:1988;15064-15070.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 15064-15070
-
-
Knauff, M.J.1
Bell, D.P.2
Hirtzer, P.3
Luo, Z.P.4
Young, J.D.5
Kartre, N.V.6
-
13
-
-
0347800842
-
Conjugation of high, molecular weight poly(ethylene glycol) to cytokines: Granulocyte-macrophage colony stimulating factors as model substrates
-
J.M. Harrris, & S. Zalipsky. Washington, DC: ACS
-
Sherman M.R., Williams L.D., Saifer M.C.P., French J.A., Kwak L.W., Oppenheim J.J. Conjugation of high, molecular weight poly(ethylene glycol) to cytokines: granulocyte-macrophage colony stimulating factors as model substrates. Harrris J.M., Zalipsky S. Poly(Ethylene Glycol): Chemistry and Biological Applications. 1997;155 ACS, Washington, DC.
-
(1997)
Poly(Ethylene Glycol): Chemistry and Biological Applications
, pp. 155
-
-
Sherman, M.R.1
Williams, L.D.2
Saifer, M.C.P.3
French, J.A.4
Kwak, L.W.5
Oppenheim, J.J.6
-
14
-
-
0028337034
-
Distribution and tissue uptake of poly(ethylene glycol) with different molecular weights after intravenous administration to mice
-
Yamaoka T., Tabata Y., Ikada Y. Distribution and tissue uptake of poly(ethylene glycol) with different molecular weights after intravenous administration to mice. J. Pharm. Sci. 83:1994;601-606.
-
(1994)
J. Pharm. Sci.
, vol.83
, pp. 601-606
-
-
Yamaoka, T.1
Tabata, Y.2
Ikada, Y.3
-
15
-
-
0028913713
-
Fate of water-soluble polymers administered via different routes
-
Yamaoka T., Tabata Y., Ikada Y. Fate of water-soluble polymers administered via different routes. J. Pharm. Sci. 84:1995;349-354.
-
(1995)
J. Pharm. Sci.
, vol.84
, pp. 349-354
-
-
Yamaoka, T.1
Tabata, Y.2
Ikada, Y.3
-
16
-
-
0030894641
-
Prolongation of the serum half-life period of superoxide dismutase by poly(ethylene glycol) modification
-
Nakaoka R., Tabata Y., Yamaoka T., Ikada Y. Prolongation of the serum half-life period of superoxide dismutase by poly(ethylene glycol) modification. J. Control. Release. 46:1997;253-262.
-
(1997)
J. Control. Release
, vol.46
, pp. 253-262
-
-
Nakaoka, R.1
Tabata, Y.2
Yamaoka, T.3
Ikada, Y.4
-
17
-
-
0002618736
-
Renal circulation and glomerular hemodynamics
-
R.W. Schrier, C.W. Gottshalk (Eds.) Little, Brown, Boston, MA
-
W.J. Arendshorst, L.G. Navar, Renal circulation and glomerular hemodynamics, in: R.W. Schrier, C.W. Gottshalk (Eds.), Diseases of the Kidney, Little, Brown, Boston, MA, 1988, p. 65.
-
(1988)
Diseases of the Kidney
, pp. 65
-
-
Arendshorst, W.J.1
Navar, L.G.2
-
18
-
-
0030871422
-
The impact of polyethylene glycol conjugation on bovine hemoglobin's circulatory half-life and renal effects in a rabbit top-loaded transfusion model
-
Conover C.D., Gilbert C.W., Shum K.L., Shorr R.L. The impact of polyethylene glycol conjugation on bovine hemoglobin's circulatory half-life and renal effects in a rabbit top-loaded transfusion model. Artif. Organs. 21:1997;907-915.
-
(1997)
Artif. Organs
, vol.21
, pp. 907-915
-
-
Conover, C.D.1
Gilbert, C.W.2
Shum, K.L.3
Shorr, R.L.4
-
19
-
-
9544220647
-
Long-acting growth hormones produced by conjugation with polyethylene glycol
-
Clark R., Olson K., Fuh G., Marian M., Mortensen D., Teshima G., Chang S., Chu H., Mukku V., Canova-Davis E., Sommers T., Cronin M., Winkler M., Wells J.A. Long-acting growth hormones produced by conjugation with polyethylene glycol. J. Biol. Chem. 271:1996;21969-21977.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21969-21977
-
-
Clark, R.1
Olson, K.2
Fuh, G.3
Marian, M.4
Mortensen, D.5
Teshima, G.6
Chang, S.7
Chu, H.8
Mukku, V.9
Canova-Davis, E.10
Sommers, T.11
Cronin, M.12
Winkler, M.13
Wells, J.A.14
-
20
-
-
0031125001
-
Improved conjugation of cytokines using high molecular weight poly(ethylene glycol): PEG-GM-CSF as prototype
-
Saifer M.G.P., Williams L.D., Sherman M.R., French J.A., Kwak L.W., Oppenheim J.J. Improved conjugation of cytokines using high molecular weight poly(ethylene glycol): PEG-GM-CSF as prototype. Polym. Preprints. 38:1997;576-577.
-
(1997)
Polym. Preprints
, vol.38
, pp. 576-577
-
-
Saifer, M.G.P.1
Williams, L.D.2
Sherman, M.R.3
French, J.A.4
Kwak, L.W.5
Oppenheim, J.J.6
-
21
-
-
0030059104
-
Site-specific attachment of functionalized poly(ethylene glycol) to the amino terminus of proteins
-
Gaertner H.F., Offord R.E. Site-specific attachment of functionalized poly(ethylene glycol) to the amino terminus of proteins. Bioconjug. Chem. 7:1996;38-44.
-
(1996)
Bioconjug. Chem.
, vol.7
, pp. 38-44
-
-
Gaertner, H.F.1
Offord, R.E.2
-
22
-
-
0034609586
-
Identification of the mayor positional isomer of pegylated interferon alpha-2b
-
Wang Y.S., Youngster S., Bausch J., Zhang R., Mc Nemar C., Wyss D.F. Identification of the mayor positional isomer of pegylated interferon alpha-2b. Biochemistry. 39:2000;10634-10640.
-
(2000)
Biochemistry
, vol.39
, pp. 10634-10640
-
-
Wang, Y.S.1
Youngster, S.2
Bausch, J.3
Zhang, R.4
Mc Nemar, C.5
Wyss, D.F.6
-
23
-
-
0029786093
-
Molecular design of hybrid tumor necrosis factor II: The molecular size of polyethylene glycol-modified tumor necrosis factor affects its antitumor potency
-
Tsutsumi Y., Tsunoda S., Kamada H., Kihira T., Nagakawa S., Kaneda Y., Kanamori T., Mayumi T. Molecular design of hybrid tumor necrosis factor II: the molecular size of polyethylene glycol-modified tumor necrosis factor affects its antitumor potency. Br. J. Cancer. 74:1996;1090-1095.
-
(1996)
Br. J. Cancer
, vol.74
, pp. 1090-1095
-
-
Tsutsumi, Y.1
Tsunoda, S.2
Kamada, H.3
Kihira, T.4
Nagakawa, S.5
Kaneda, Y.6
Kanamori, T.7
Mayumi, T.8
-
24
-
-
0000981509
-
Preparation and characterization of polyethylene-glycol-modified salmon calictonins
-
Lee K.C., Tak K.K., Park M.O., Lee J.T., Na D.H., Yoo S.D., Lee H.S., DeLuca P.P. Preparation and characterization of polyethylene-glycol-modified salmon calictonins. Pharm. Dev. Technol. 4:1999;269.
-
(1999)
Pharm. Dev. Technol.
, vol.4
, pp. 269
-
-
Lee, K.C.1
Tak, K.K.2
Park, M.O.3
Lee, J.T.4
Na, D.H.5
Yoo, S.D.6
Lee, H.S.7
Deluca, P.P.8
-
25
-
-
0035086519
-
Rational design of a potent, long lasting form of interferon: A 40 kDa branched polyethylene glycol-conjugated interferon-2a for the treatment of hepatitis C
-
Bailon P., Palleroni A., Schaffer C.A., Spence C.L., Fung W.J., Porter J.E., Enrich G.K., Pan W., Xu Z.X., Modi M.W., Farod A., Berthold W. Rational design of a potent, long lasting form of interferon: a 40 kDa branched polyethylene glycol-conjugated interferon-2a for the treatment of hepatitis C. Bioconjug. Chem. 12:2001;195-202.
-
(2001)
Bioconjug. Chem.
, vol.12
, pp. 195-202
-
-
Bailon, P.1
Palleroni, A.2
Schaffer, C.A.3
Spence, C.L.4
Fung, W.J.5
Porter, J.E.6
Enrich, G.K.7
Pan, W.8
Xu, Z.X.9
Modi, M.W.10
Farod, A.11
Berthold, W.12
-
26
-
-
0034732059
-
Modulating pharmacokinetics of an anti-interleukin-8 F(ab′)2 by amine-specific PEGylation with preserved bioactivity
-
Koumenis I., Sshahrokh Z., Leong S., Hsei V., Deforge L., Zapata G. Modulating pharmacokinetics of an anti-interleukin-8 F(ab′)2 by amine-specific PEGylation with preserved bioactivity. Int. J. Pharm. 198:2000;83-95.
-
(2000)
Int. J. Pharm.
, vol.198
, pp. 83-95
-
-
Koumenis, I.1
Sshahrokh, Z.2
Leong, S.3
Hsei, V.4
Deforge, L.5
Zapata, G.6
-
27
-
-
0032868653
-
Therapeutic antibody fragments with prolonged in vivo half-lives
-
Chapman A.P., Antoniw P., Spitali M., West S., Stephens S., King D.J. Therapeutic antibody fragments with prolonged in vivo half-lives. Nat. Biotechnol. 17:1999;780-783.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 780-783
-
-
Chapman, A.P.1
Antoniw, P.2
Spitali, M.3
West, S.4
Stephens, S.5
King, D.J.6
-
28
-
-
0345504113
-
Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: A comparison of conjugation chemistries and compounds
-
Lee L.S., Connover C., Shi C., Whiltlow M., Fipula D. Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: a comparison of conjugation chemistries and compounds. Bioconjug. Chem. 10:1999;973-981.
-
(1999)
Bioconjug. Chem.
, vol.10
, pp. 973-981
-
-
Lee, L.S.1
Connover, C.2
Shi, C.3
Whiltlow, M.4
Fipula, D.5
-
29
-
-
0002635147
-
-
J. Orloff, & R.W. Berliner. Bethesda, MD: American Physiological Society
-
Renkin E.M., Gilmore J.P. Orloff J., Berliner R.W. Renal Physiology. 1973;185-248 American Physiological Society, Bethesda, MD.
-
(1973)
Renal Physiology
, pp. 185-248
-
-
Renkin, E.M.1
Gilmore, J.P.2
-
30
-
-
0032725837
-
PEGylated recombinant human soluble tumor necrosis factor receptor type I (r-Hu-sTNF-RI) novel high affinity TNF receptor designed for chronic inflammatory disease
-
Edwards C.K. PEGylated recombinant human soluble tumor necrosis factor receptor type I (r-Hu-sTNF-RI) novel high affinity TNF receptor designed for chronic inflammatory disease. Ann. Rheum. Dis. 58:1999;173-181.
-
(1999)
Ann. Rheum. Dis.
, vol.58
, pp. 173-181
-
-
Edwards, C.K.1
-
31
-
-
0027473377
-
Hepatic excretion and metabolism of polyethylene glycols and mannitol in the cat
-
Friman S., Egestad B., Sjövall J., Svanvik J. Hepatic excretion and metabolism of polyethylene glycols and mannitol in the cat. J. Hepatol. 17:1993;48-55.
-
(1993)
J. Hepatol.
, vol.17
, pp. 48-55
-
-
Friman, S.1
Egestad, B.2
Sjövall, J.3
Svanvik, J.4
-
32
-
-
0025001822
-
Effect of cytochrome P-450 inhibition and stimulation on intensity of polyethylene degradation in microsomal fraction of mouse and rat livers
-
Beranová M., Wasserbauer R., Vanèurová D., Štifter M., Ocenášková J., Mára M. Effect of cytochrome P-450 inhibition and stimulation on intensity of polyethylene degradation in microsomal fraction of mouse and rat livers. Biomaterials. 11:1990.
-
(1990)
Biomaterials
, vol.11
-
-
Beranová, M.1
Wasserbauer, R.2
Vanèurová, D.3
Štifter, M.4
Ocenášková, J.5
Mára, M.6
-
33
-
-
0033654389
-
Modulation of the pharmacokinetics and pharmacodynamics of proteins by polyethylene glycol conjugation
-
Mehvar R. Modulation of the pharmacokinetics and pharmacodynamics of proteins by polyethylene glycol conjugation. J. Pharm. Pharm. Sci. 3:(1):2000;125-136.
-
(2000)
J. Pharm. Pharm. Sci.
, vol.3
, Issue.1
, pp. 125-136
-
-
Mehvar, R.1
-
34
-
-
0024548507
-
Oxidation of polyethylene glycols by alcohol dehydrogenase
-
Herold D.A., Keil K., Bruns D.E. Oxidation of polyethylene glycols by alcohol dehydrogenase. Biochem. Pharmacol. 38:(1):1989;73-76.
-
(1989)
Biochem. Pharmacol.
, vol.38
, Issue.1
, pp. 73-76
-
-
Herold, D.A.1
Keil, K.2
Bruns, D.E.3
-
35
-
-
0030862261
-
Thermal/oxidative degradation and stabilization of polyethylene glycol
-
Seongok H., Chongyoup K., Kwon D. Thermal/oxidative degradation and stabilization of polyethylene glycol. Polymer. 38:1997;317-323.
-
(1997)
Polymer
, vol.38
, pp. 317-323
-
-
Seongok, H.1
Chongyoup, K.2
Kwon, D.3
-
37
-
-
0025128987
-
Immunogenicity of recombinant IL-2 modified by covalent attachment of polyethylene glycol
-
Kartre N.V. Immunogenicity of recombinant IL-2 modified by covalent attachment of polyethylene glycol. J. Immunol. 144:1990;209-213.
-
(1990)
J. Immunol.
, vol.144
, pp. 209-213
-
-
Kartre, N.V.1
-
38
-
-
0017701219
-
Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol
-
Abuchowski A.A., van Es T., C Palczuk N., Davis F.F. Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol. J. Biol. Chem. 252:1977;3578-3581.
-
(1977)
J. Biol. Chem.
, vol.252
, pp. 3578-3581
-
-
Abuchowski, A.A.1
Van Es, T.2
Palczuk, N.C.3
Davis, F.F.4
-
39
-
-
0001362058
-
Reduction of immunogenicity and extension of circulating half-life of peptides and proteins
-
V.H.L. Lee. New York: Mercel Dekker
-
Davis F.F., Kazo G.M., Nucci M.L., Abuchowski A. Reduction of immunogenicity and extension of circulating half-life of peptides and proteins. Lee V.H.L. Peptide and Protein Drug Delivery. 1991;831 Mercel Dekker, New York.
-
(1991)
Peptide and Protein Drug Delivery
, pp. 831
-
-
Davis, F.F.1
Kazo, G.M.2
Nucci, M.L.3
Abuchowski, A.4
-
40
-
-
0026118928
-
Suppression of antibody responses by conjugates of antigens and monomethoxypoly(ethylene glycol)
-
Sehon A.H. Suppression of antibody responses by conjugates of antigens and monomethoxypoly(ethylene glycol). Adv. Drug Deliv. Rev. 6:1991;203-217.
-
(1991)
Adv. Drug Deliv. Rev.
, vol.6
, pp. 203-217
-
-
Sehon, A.H.1
-
41
-
-
0033618471
-
Immunogenic and tolerogenic properties of monomethoxypoly(ethylene glycol) conjugated proteins
-
Caliceti P., Veronese F.M., Jonak Z. Immunogenic and tolerogenic properties of monomethoxypoly(ethylene glycol) conjugated proteins. Farmaco. 54:1999;430-437.
-
(1999)
Farmaco
, vol.54
, pp. 430-437
-
-
Caliceti, P.1
Veronese, F.M.2
Jonak, Z.3
-
42
-
-
0020698112
-
Antibodies against polyethylene glycol produced in animals by immunization with monomethoxy polyethylene glycol modified proteins
-
Richter A.W., Akerblom E. Antibodies against polyethylene glycol produced in animals by immunization with monomethoxy polyethylene glycol modified proteins. Int. Arch. Allergy Appl. Immunol. 70:1983;124-131.
-
(1983)
Int. Arch. Allergy Appl. Immunol.
, vol.70
, pp. 124-131
-
-
Richter, A.W.1
Akerblom, E.2
-
43
-
-
0021246228
-
Polyethylene glycol reactive antibodies in man: Titer distribution in allergic patients treated with monomethoxy polyethylene glycol modified allergens or placebo, and healthy blood donors
-
Richter A.W., Akerblom E. Polyethylene glycol reactive antibodies in man: titer distribution in allergic patients treated with monomethoxy polyethylene glycol modified allergens or placebo, and healthy blood donors. Int. Arch. Allergy Appl. Immunol. 74:1984;36-39.
-
(1984)
Int. Arch. Allergy Appl. Immunol.
, vol.74
, pp. 36-39
-
-
Richter, A.W.1
Akerblom, E.2
-
44
-
-
0022181599
-
Studies on antigenicity of polyethylene glycol (PEG)-modified uricase
-
Tsuji J.-C., Hirose K. Studies on antigenicity of polyethylene glycol (PEG)-modified uricase. Int. J. Immunopharmacol. 7:1985;725-730.
-
(1985)
Int. J. Immunopharmacol.
, vol.7
, pp. 725-730
-
-
Tsuji, J.-C.1
Hirose, K.2
-
45
-
-
0034918665
-
Immunological properties of usricase conjugated to neutral soluble polymers
-
Caliceti P., Schiavon O., Veronese F.M. Immunological properties of usricase conjugated to neutral soluble polymers. Bioconjug. Chem. 12:2001;515-522.
-
(2001)
Bioconjug. Chem.
, vol.12
, pp. 515-522
-
-
Caliceti, P.1
Schiavon, O.2
Veronese, F.M.3
-
46
-
-
0037124466
-
PEGylated antibodies and antibody fragments for improved therapy: A review
-
Chapman A.P. PEGylated antibodies and antibody fragments for improved therapy: a review. Adv. Drug Deliv. Rev. 54:2002;531-545.
-
(2002)
Adv. Drug Deliv. Rev.
, vol.54
, pp. 531-545
-
-
Chapman, A.P.1
-
47
-
-
0029888326
-
Improvement of pharmacokinetic, immunological and stability properties of asparginase by conjugation of linear and branched monomethoxy poly(ethylene glycol)
-
Veronese F.M., Monfardini C., Caliceti P., Schiavon O., Scrawen M.D., Beer D. Improvement of pharmacokinetic, immunological and stability properties of asparginase by conjugation of linear and branched monomethoxy poly(ethylene glycol). J. Control. Release. 40:1966;199-209.
-
(1966)
J. Control. Release
, vol.40
, pp. 199-209
-
-
Veronese, F.M.1
Monfardini, C.2
Caliceti, P.3
Schiavon, O.4
Scrawen, M.D.5
Beer, D.6
-
48
-
-
0033136959
-
Accelerated clearance of polyethylene glycol-modified proteins by anti-polyethylene glycol IgM
-
Cheng T.L., Wu P.Y., Wu M.F., Chern J.W., Roffler S.R. Accelerated clearance of polyethylene glycol-modified proteins by anti-polyethylene glycol IgM. Bioconjug. Chem. 10:1999;520-528.
-
(1999)
Bioconjug. Chem.
, vol.10
, pp. 520-528
-
-
Cheng, T.L.1
Wu, P.Y.2
Wu, M.F.3
Chern, J.W.4
Roffler, S.R.5
-
49
-
-
0034023632
-
Efficient clearance of poly(ethylene glycol)-modified immunoenzyme with anti-PEG monoclonal antibody for prodrug cancer therapy
-
Cheng T.L., Cheng B.M., W Chern J., Wu M.F., Roffler S.R. Efficient clearance of poly(ethylene glycol)-modified immunoenzyme with anti-PEG monoclonal antibody for prodrug cancer therapy. Bioconjug. Chem. 11:2000;258-266.
-
(2000)
Bioconjug. Chem.
, vol.11
, pp. 258-266
-
-
Cheng, T.L.1
Cheng, B.M.2
Chern, J.W.3
Wu, M.F.4
Roffler, S.R.5
-
50
-
-
0034142197
-
Pharmacokinetic and thromolytic properties of cysteine-linked polyethylene glycol derivatives of staphylokinase
-
Wanwetswinkel S., Plaisance S., Zhi-yong Z., Vanlinthout I., Brepoeles K., Lasters I., Collen D., Jespers L. Pharmacokinetic and thromolytic properties of cysteine-linked polyethylene glycol derivatives of staphylokinase. Blood. 95:2000;936-942.
-
(2000)
Blood
, vol.95
, pp. 936-942
-
-
Wanwetswinkel, S.1
Plaisance, S.2
Zhi-Yong, Z.3
Vanlinthout, I.4
Brepoeles, K.5
Lasters, I.6
Collen, D.7
Jespers, L.8
-
51
-
-
0032126845
-
Pegylation of cytokines and other therapeutic proteins and peptides: The importance of biological optimization of coupling techniques
-
Francis G.E., Fisher D., Delgado C., Malik F., Gardiner A., Neale D. Pegylation of cytokines and other therapeutic proteins and peptides: the importance of biological optimization of coupling techniques. Int. J. Hematol. 68:1998;1-18.
-
(1998)
Int. J. Hematol.
, vol.68
, pp. 1-18
-
-
Francis, G.E.1
Fisher, D.2
Delgado, C.3
Malik, F.4
Gardiner, A.5
Neale, D.6
-
52
-
-
0029015672
-
Comparison of body distribution of poly(vinyl alcohol) with other water-soluble polymers after intravenous injection
-
Yamaoka T., Tabata Y., Ikada Y. Comparison of body distribution of poly(vinyl alcohol) with other water-soluble polymers after intravenous injection. J. Pharm. Pharmacol. 47:1995;479-486.
-
(1995)
J. Pharm. Pharmacol.
, vol.47
, pp. 479-486
-
-
Yamaoka, T.1
Tabata, Y.2
Ikada, Y.3
-
53
-
-
0032925686
-
Targeted delivery and improved therapeutic potential of catalase by chemical modification: Combination with superoxide dismutase
-
Yabe Y., Nishikawa M., Tamada A., Takakura Y., Hashida M. Targeted delivery and improved therapeutic potential of catalase by chemical modification: combination with superoxide dismutase. J. Pharmacol. Exp. Ther. 289:1999;1176-1184.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, pp. 1176-1184
-
-
Yabe, Y.1
Nishikawa, M.2
Tamada, A.3
Takakura, Y.4
Hashida, M.5
-
54
-
-
0033167240
-
Biopharmaceutical properties of uricase conjugated to neutral and amphiphilic polymers
-
Caliceti P., Schiavon O., Veronese F.M. Biopharmaceutical properties of uricase conjugated to neutral and amphiphilic polymers. Bioconjug. Chem. 10:1999;638-646.
-
(1999)
Bioconjug. Chem.
, vol.10
, pp. 638-646
-
-
Caliceti, P.1
Schiavon, O.2
Veronese, F.M.3
-
55
-
-
0029422348
-
Distribution of catalase, ribonuclease, superoxide dismutase modified by monomethoxy(polyethylene glycol) into rat cerebral lymph and lymphatic nodes
-
Lamka J., Schiavon O., Laznicek M., Caliceti P., M Veronese F. Distribution of catalase, ribonuclease, superoxide dismutase modified by monomethoxy(polyethylene glycol) into rat cerebral lymph and lymphatic nodes. Physiol. Res. 44:1995;307-313.
-
(1995)
Physiol. Res.
, vol.44
, pp. 307-313
-
-
Lamka, J.1
Schiavon, O.2
Laznicek, M.3
Caliceti, P.4
Veronese, F.M.5
-
56
-
-
0034079580
-
Plasma and lymph pharmacokinetics of recombinant human interleukin-2 and polyethylene glycol-modified interleukin-2 in pigs
-
Chen S.A., Sawchuk R.J., Brundage R.C., Horvath C., Mendenhall H.V., Gunther R.A., Braeckman R.A. Plasma and lymph pharmacokinetics of recombinant human interleukin-2 and polyethylene glycol-modified interleukin-2 in pigs. J. Pharmacol. Exp. Ther. 293:2000;248-259.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.293
, pp. 248-259
-
-
Chen, S.A.1
Sawchuk, R.J.2
Brundage, R.C.3
Horvath, C.4
Mendenhall, H.V.5
Gunther, R.A.6
Braeckman, R.A.7
-
57
-
-
0004386069
-
Factors affecting the lymphatic absorption of macromolecules following extravascular administration
-
Xie D., Hale V.G. Factors affecting the lymphatic absorption of macromolecules following extravascular administration. Pharm. Res. 13:1996;S-396.
-
(1996)
Pharm. Res.
, vol.13
, pp. 396
-
-
Xie, D.1
Hale, V.G.2
-
59
-
-
0029039418
-
Influence of molecular weight on passive tumor accumulation of a soluble macromolecular drug carrier
-
Seymour L.W., Miyamoto Y., Maeda H., Brereton M., Strohalm J., Ulbrich K., Duncan R. Influence of molecular weight on passive tumor accumulation of a soluble macromolecular drug carrier. Eur. J. Cancer. 31:1995;766-770.
-
(1995)
Eur. J. Cancer
, vol.31
, pp. 766-770
-
-
Seymour, L.W.1
Miyamoto, Y.2
Maeda, H.3
Brereton, M.4
Strohalm, J.5
Ulbrich, K.6
Duncan, R.7
-
60
-
-
0033965528
-
Tumor-targeting chemotherapy by a xanthine oxidase polymer conjugate that generates oxygen-free radicals in tumor tissue
-
Sawa T., Wu J., Akaike T., Maeda H. Tumor-targeting chemotherapy by a xanthine oxidase polymer conjugate that generates oxygen-free radicals in tumor tissue. Cancer Res. 60:2000;666-671.
-
(2000)
Cancer Res.
, vol.60
, pp. 666-671
-
-
Sawa, T.1
Wu, J.2
Akaike, T.3
Maeda, H.4
-
61
-
-
0032007236
-
Polyethylene glycol conjugation of recombinant methioninase for cancer therapy
-
Tan Y., Sun X., Xu M., An Z., Tan X., Han Q., Miljkovich D.A., Yung M.R., Hoffman M. Polyethylene glycol conjugation of recombinant methioninase for cancer therapy. Protein Expr. Purif. 12:1998;45-52.
-
(1998)
Protein Expr. Purif.
, vol.12
, pp. 45-52
-
-
Tan, Y.1
Sun, X.2
Xu, M.3
An, Z.4
Tan, X.5
Han, Q.6
Miljkovich, D.A.7
Yung, M.R.8
Hoffman, M.9
-
62
-
-
0030843862
-
Poly(ethylene glycol) modification of b-glucuronidase-antibody conjugates for solid-tumor therapy by targeted activation of glucuronide prodrugs
-
Cheng T.L., Chen B.M., Chan L.Y., Wu P.Y., Chern J.W., Roffler S.R. Poly(ethylene glycol) modification of b-glucuronidase-antibody conjugates for solid-tumor therapy by targeted activation of glucuronide prodrugs. Cancer Immunol. Immunother. 44:1997;305-315.
-
(1997)
Cancer Immunol. Immunother.
, vol.44
, pp. 305-315
-
-
Cheng, T.L.1
Chen, B.M.2
Chan, L.Y.3
Wu, P.Y.4
Chern, J.W.5
Roffler, S.R.6
-
63
-
-
0034255680
-
Pharmacokinetics and microdistribution of polyethylene glycol-modified humanized A33 antibody targeting colon cancer xenografts
-
Deckert P.M., Jungbluth A., Montalto N., Clark M.A., Finn R.D., Williams C., Righards E.C., Panageas K.S., Old L.J., Welt S. Pharmacokinetics and microdistribution of polyethylene glycol-modified humanized A33 antibody targeting colon cancer xenografts. Int. J. Cancer. 87:2000;832-839.
-
(2000)
Int. J. Cancer
, vol.87
, pp. 832-839
-
-
Deckert, P.M.1
Jungbluth, A.2
Montalto, N.3
Clark, M.A.4
Finn, R.D.5
Williams, C.6
Righards, E.C.7
Panageas, K.S.8
Old, L.J.9
Welt, S.10
-
64
-
-
0030061068
-
Enhanced tumor specificity of an anti-carcinoembrionic antigen Fab′ fragment by poly(ethylene glycol) (PEG) modification
-
Delgado C., Pedley R.B., Herraz A., Boden R., Boden J.A., Keep P.A., Chester K.A., Fisher D., Begent R.H.J., Francis G.E. Enhanced tumor specificity of an anti-carcinoembrionic antigen Fab′ fragment by poly(ethylene glycol) (PEG) modification. Br. J. Cancer. 73:1996;175-182.
-
(1996)
Br. J. Cancer
, vol.73
, pp. 175-182
-
-
Delgado, C.1
Pedley, R.B.2
Herraz, A.3
Boden, R.4
Boden, J.A.5
Keep, P.A.6
Chester, K.A.7
Fisher, D.8
Begent, R.H.J.9
Francis, G.E.10
-
65
-
-
0030047854
-
Polyethylene glycol modification: Relevance of improved methodology to tumor targeting
-
Francis G.E., Delgado C., Fisher D., Malik F., Agrawal A.K. Polyethylene glycol modification: relevance of improved methodology to tumor targeting. J. Drug Target. 3:1996;321-340.
-
(1996)
J. Drug Target.
, vol.3
, pp. 321-340
-
-
Francis, G.E.1
Delgado, C.2
Fisher, D.3
Malik, F.4
Agrawal, A.K.5
-
66
-
-
0025014962
-
Physiological barriers to delivery monoclonal antibodies and other macromolecules to tumors
-
Jain R.K. Physiological barriers to delivery monoclonal antibodies and other macromolecules to tumors. Cancer Res. 50:1990;814s-819.
-
(1990)
Cancer Res.
, vol.50
-
-
Jain, R.K.1
-
67
-
-
0033944158
-
Inhibition of tumor growth by poly(ethylene glycol) derivatives of anti-ErbB2 antibodies
-
Hurwitz E., Klapper L.N., Wilchek M., Yarden Y., Sela M. Inhibition of tumor growth by poly(ethylene glycol) derivatives of anti-ErbB2 antibodies. Cancer Immunol. Immunother. 49:2000;226-234.
-
(2000)
Cancer Immunol. Immunother.
, vol.49
, pp. 226-234
-
-
Hurwitz, E.1
Klapper, L.N.2
Wilchek, M.3
Yarden, Y.4
Sela, M.5
-
68
-
-
0025999938
-
Comparative pharmacokinetic properties of murine monoclonal antibodies A7 modified with neocarzinostatin, dextran and polyethylene glycol
-
Takashina K., Kitamura K., Yamaguchi T., Noguchi A., Noguchi A., Tsurumi H. Comparative pharmacokinetic properties of murine monoclonal antibodies A7 modified with neocarzinostatin, dextran and polyethylene glycol. Jpn. J. Cancer Res. 82:1991;1145-1150.
-
(1991)
Jpn. J. Cancer Res.
, vol.82
, pp. 1145-1150
-
-
Takashina, K.1
Kitamura, K.2
Yamaguchi, T.3
Noguchi, A.4
Noguchi, A.5
Tsurumi, H.6
-
69
-
-
0025993967
-
Chemical engineering of the monoclonal antibody A7 by polyethylene glycol for targeting cancer chemotherapy
-
Kitamura K., Takahashi T., Yamaguchi T., Noguchi A., Noguchi A., Takashina K., Tsurumi H., Inagake M., Toyokuni T., Hakamori S. Chemical engineering of the monoclonal antibody A7 by polyethylene glycol for targeting cancer chemotherapy. Cancer Res. 51:1991;4310-4315.
-
(1991)
Cancer Res.
, vol.51
, pp. 4310-4315
-
-
Kitamura, K.1
Takahashi, T.2
Yamaguchi, T.3
Noguchi, A.4
Noguchi, A.5
Takashina, K.6
Tsurumi, H.7
Inagake, M.8
Toyokuni, T.9
Hakamori, S.10
-
70
-
-
0032126044
-
Stabilization of substances in circulation
-
Monfardini C., Veronese F.M. Stabilization of substances in circulation. Bioconjug. Chem. 9:1998;418-450.
-
(1998)
Bioconjug. Chem.
, vol.9
, pp. 418-450
-
-
Monfardini, C.1
Veronese, F.M.2
-
71
-
-
0025019752
-
The clinical efficacy of polyethylene glycol)-modified proteins
-
Fuertges F., Abuchoswski A. The clinical efficacy of polyethylene glycol)-modified proteins. J. Control. Release. 11:1990;139-148.
-
(1990)
J. Control. Release
, vol.11
, pp. 139-148
-
-
Fuertges, F.1
Abuchoswski, A.2
-
72
-
-
0024437046
-
Preparation, physico-chemical and pharmacokinetic characterization of monomethoxypoly(ethylene glycol)-derivatized superoxide dismutase
-
Veronese F.M., Caliceti P., Pastorino A., Schiavon O., Sartore L., Banci L., Monsu Scolaro L. Preparation, physico-chemical and pharmacokinetic characterization of monomethoxypoly(ethylene glycol)-derivatized superoxide dismutase. J. Control. Release. 10:1989;145-154.
-
(1989)
J. Control. Release
, vol.10
, pp. 145-154
-
-
Veronese, F.M.1
Caliceti, P.2
Pastorino, A.3
Schiavon, O.4
Sartore, L.5
Banci, L.6
Monsu Scolaro, L.7
-
73
-
-
0029928302
-
-
Jensen-Pippo K.E., Whitcomb K.L., DePrince R.B., Ralph L., Habberfield A.D. Pharm. Res. 13:1996;102-107.
-
(1996)
Pharm. Res.
, vol.13
, pp. 102-107
-
-
Jensen-Pippo, K.E.1
Whitcomb, K.L.2
Deprince, R.B.3
Ralph, L.4
Habberfield, A.D.5
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