Biocompatibility of ABA triblock copolymer microparticles consisting of poly(L-lactic-co-glycolic-acid) A-blocks attached to central poly(oxyethylene) B-blocks in rats after intramuscular injection

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 43, Issue 1, 1997, Pages 19-28

  Ronneberger, Birgit ^a   Kissel, Thomas ^a   Anderson, James M ^b,c  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ABA triblock copolymer; Biocompatibility; Foreign body reaction; Histology in rats; Inflammation; Microparticles; Poly(lactide co glycolide) copolymer; Poly(oxyethylene)

Indexed keywords

COPOLYMER; POLOXAMER; POLYGLACTIN;

ANIMAL EXPERIMENT; ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG UPTAKE; FOREIGN BODY REACTION; GRANULATION TISSUE; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; NONHUMAN; RAT;

EID: 0031398520     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(96)00006-9     Document Type: Article

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