High incidence of medulloblastoma following X-ray-irradiation of newborn Ptc1 heterozygous mice

Oncogene

Volumn 21, Issue 49, 2002, Pages 7580-7584

  Pazzaglia, Simonetta ^a   Mancuso, Mariateresa ^a   Atkinson, Michael J ^b   Tanori, Mirella ^c   Rebessi, Simonetta ^a   Di Majo, Vincenzo ^a   Covelli, Vincenzo ^a,c   Hahn, Heidi ^d   Saran, Anna ^a  

^a ENEA C R CASACCIA   (Italy)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c NATIONAL CANCER INSTITUTE   (Italy)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

LOH; Medulloblastoma; Patched knockout mice; X rays

Indexed keywords

GENE PRODUCT; PROTEIN PATCHED 1; UNCLASSIFIED DRUG;

ALLELISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CONTROLLED STUDY; GENE MUTATION; HETEROZYGOSITY LOSS; IONIZING RADIATION; MEDULLOBLASTOMA; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RADIATION INJURY; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; INCIDENCE; LOSS OF HETEROZYGOSITY; MEDULLOBLASTOMA; MICE; NEOPLASMS, RADIATION-INDUCED; ONCOGENE PROTEINS, FUSION; PROTEIN-TYROSINE KINASES;

ANIMALIA;

EID: 0037168206     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1205973     Document Type: Article

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