-
1
-
-
0024536654
-
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
-
Baker, S.J., Fearon, E.R., Nigro, J.M., Hamilton, S.R., Preisinger, A.C., Jessup, J.M., vanTuinen, P., Ledbetter, D.H., Barker, D.F., Nakamura, Y., White, R. and Vogelstein, B. (1989) Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 244:217-221.
-
(1989)
Science
, vol.244
, pp. 217-221
-
-
Baker, S.J.1
Fearon, E.R.2
Nigro, J.M.3
Hamilton, S.R.4
Preisinger, A.C.5
Jessup, J.M.6
VanTuinen, P.7
Ledbetter, D.H.8
Barker, D.F.9
Nakamura, Y.10
White, R.11
Vogelstein, B.12
-
2
-
-
0035555650
-
Activation and activities of the p53 tumour suppressor protein
-
Balint, E.E. and Vousden, K.H. (2001) Activation and activities of the p53 tumour suppressor protein. Br J Cancer 85:1813-1823.
-
(2001)
Br J Cancer
, vol.85
, pp. 1813-1823
-
-
Balint, E.E.1
Vousden, K.H.2
-
3
-
-
0030112020
-
P53, apoptosis, and breast cancer
-
Barnes, D.M. and Camplejohn, R.S. (1996) P53, apoptosis, and breast cancer. J Mammary Gland Biol Neoplasia 1:163-175.
-
(1996)
J Mammary Gland Biol Neoplasia
, vol.1
, pp. 163-175
-
-
Barnes, D.M.1
Camplejohn, R.S.2
-
4
-
-
0020339943
-
Radioimmunoassay of the cellular protein p53 in mouse and human cell lines
-
Benchimol, S., Pim, D. and Crawford, L. (1982) Radioimmunoassay of the cellular protein p53 in mouse and human cell lines. EMBO J 1:1055-1062.
-
(1982)
EMBO J
, vol.1
, pp. 1055-1062
-
-
Benchimol, S.1
Pim, D.2
Crawford, L.3
-
5
-
-
19844376859
-
Mdm2 and mdmX prevent ASPP1 and ASPP2 from stimulating p53 without targeting p53 for degradation
-
Bergamaschi, D., Samuels, Y., Zhong, S. and Lu, X. (2005) Mdm2 and mdmX prevent ASPP1 and ASPP2 from stimulating p53 without targeting p53 for degradation. Oncogene 24:3836-3841.
-
(2005)
Oncogene
, vol.24
, pp. 3836-3841
-
-
Bergamaschi, D.1
Samuels, Y.2
Zhong, S.3
Lu, X.4
-
6
-
-
0035797528
-
Relative frequency and morphology of cancers in carriers of germline TP53 mutations
-
Birch, J.M., Alston, R.D., McNally, R.J., Evans, D.G., Kelsey, A.M., Harris, M., Eden, O.B. and Varley, J.M. (2001) Relative frequency and morphology of cancers in carriers of germline TP53 mutations. Oncogene 20:4621-4628.
-
(2001)
Oncogene
, vol.20
, pp. 4621-4628
-
-
Birch, J.M.1
Alston, R.D.2
McNally, R.J.3
Evans, D.G.4
Kelsey, A.M.5
Harris, M.6
Eden, O.B.7
Varley, J.M.8
-
7
-
-
0032480248
-
Cancer phenotype correlates with constitutional TP53 genotype in families with the Li-Fraumeni syndrome
-
Birch, J.M., Blair, V., Kelsey, A.M., Evans, D.G., Harris, M., Tricker, K.J. and Varley, J.M. (1998) Cancer phenotype correlates with constitutional TP53 genotype in families with the Li-Fraumeni syndrome. Oncogene 17:1061-1068.
-
(1998)
Oncogene
, vol.17
, pp. 1061-1068
-
-
Birch, J.M.1
Blair, V.2
Kelsey, A.M.3
Evans, D.G.4
Harris, M.5
Tricker, K.J.6
Varley, J.M.7
-
8
-
-
0030705168
-
Loss of function and p53 protein stabilization
-
Blagosklonny, M.V. (1997) Loss of function and p53 protein stabilization. Oncogene 15:1889-1893.
-
(1997)
Oncogene
, vol.15
, pp. 1889-1893
-
-
Blagosklonny, M.V.1
-
9
-
-
0024505911
-
Ability of p53 and the adenovirus E1b 58-kilodalton protein to form a complex is determined by p53
-
Braithwaite, A.W. and Jenkins, J.R. (1989) Ability of p53 and the adenovirus E1b 58-kilodalton protein to form a complex is determined by p53. J Virol 63:1792-1799.
-
(1989)
J Virol
, vol.63
, pp. 1792-1799
-
-
Braithwaite, A.W.1
Jenkins, J.R.2
-
10
-
-
10544222831
-
Differentiation of bacterial 16S rRNA genes and intergenic regions and Mycobacterium tuberculosis katG genes by 4tructure-specific endonuclease cleavage
-
Brow, M.A., Oldenburg, M.C., Lyamichev, V., Heisler, L.M., Lyamicheva, N., Hall, J.G., Eagan, N.J., Olive, D.M., Smith, L.M., Fors, L. and Dahlberg, J.E. (1996) Differentiation of bacterial 16S rRNA genes and intergenic regions and Mycobacterium tuberculosis katG genes by 4tructure-specific endonuclease cleavage. J Clin Microbiol 34:3129-3137.
-
(1996)
J Clin Microbiol
, vol.34
, pp. 3129-3137
-
-
Brow, M.A.1
Oldenburg, M.C.2
Lyamichev, V.3
Heisler, L.M.4
Lyamicheva, N.5
Hall, J.G.6
Eagan, N.J.7
Olive, D.M.8
Smith, L.M.9
Fors, L.10
Dahlberg, J.E.11
-
11
-
-
0348050001
-
The European flounder (Platichthys flesus) TP53 functions as a temperature-sensitive transcription factor which inhibits cell growth in yeast
-
Cachot, J., Flaman, J.M., Frebourg, T. and Leboulenger, F. (2004) The European flounder (Platichthys flesus) TP53 functions as a temperature-sensitive transcription factor which inhibits cell growth in yeast. Gene 324:97-104.
-
(2004)
Gene
, vol.324
, pp. 97-104
-
-
Cachot, J.1
Flaman, J.M.2
Frebourg, T.3
Leboulenger, F.4
-
12
-
-
0029103123
-
A possible screening test for inherited p53-related defects based on the apoptotic response of peripheral blood lymphocytes to DNA damage
-
Camplejohn, R.S., Perry, P., Hodgson, S.V., Turner, G., Williams, A., Upton, C., MacGeoch, C., Mohammed, S. and Barnes, D.M. (1995) A possible screening test for inherited p53-related defects based on the apoptotic response of peripheral blood lymphocytes to DNA damage. Br J Cancer 72:654-662.
-
(1995)
Br J Cancer
, vol.72
, pp. 654-662
-
-
Camplejohn, R.S.1
Perry, P.2
Hodgson, S.V.3
Turner, G.4
Williams, A.5
Upton, C.6
MacGeoch, C.7
Mohammed, S.8
Barnes, D.M.9
-
13
-
-
0035858984
-
p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements
-
Campomenosi, P., Monti, P., Aprile, A., Abbondandolo, A., Frebourg, T., Gold, B., Crook, T., Inga, A., Resnick, M.A., Iggo, R. and Fronza, G. (2001) p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements. Oncogene 20:3573-3579.
-
(2001)
Oncogene
, vol.20
, pp. 3573-3579
-
-
Campomenosi, P.1
Monti, P.2
Aprile, A.3
Abbondandolo, A.4
Frebourg, T.5
Gold, B.6
Crook, T.7
Inga, A.8
Resnick, M.A.9
Iggo, R.10
Fronza, G.11
-
14
-
-
0041732392
-
In vitro aflatoxin B1-induced p53 mutations
-
Chan, K.T., Hsieh, D.P. and Lung, M.L. (2003) In vitro aflatoxin B1-induced p53 mutations. Cancer Lett 199:1-7.
-
(2003)
Cancer Lett
, vol.199
, pp. 1-7
-
-
Chan, K.T.1
Hsieh, D.P.2
Lung, M.L.3
-
15
-
-
0032785881
-
Prognostic significance of p53 mutation in breast cancer: Frequent detection of non-missense mutations by yeast functional assay
-
Chappuis, P.O., Estreicher, A., Dieterich, B., Bonnefoi, H., Otter, M., Sappino, A.P. and Iggo, R. (1999) Prognostic significance of p53 mutation in breast cancer: frequent detection of non-missense mutations by yeast functional assay. Int J Cancer 84:587-593.
-
(1999)
Int J Cancer
, vol.84
, pp. 587-593
-
-
Chappuis, P.O.1
Estreicher, A.2
Dieterich, B.3
Bonnefoi, H.4
Otter, M.5
Sappino, A.P.6
Iggo, R.7
-
16
-
-
0028098165
-
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
-
Cordon-Cardo, C., Latres, E., Drobnjak, M., Oliva, M.R., Pollack, D., Woodruff, J.M., Marechal, V., Chen, J., Brennan, M.F. and Levine, A.J. (1994) Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res 54:794-799.
-
(1994)
Cancer Res
, vol.54
, pp. 794-799
-
-
Cordon-Cardo, C.1
Latres, E.2
Drobnjak, M.3
Oliva, M.R.4
Pollack, D.5
Woodruff, J.M.6
Marechal, V.7
Chen, J.8
Brennan, M.F.9
Levine, A.J.10
-
17
-
-
7844247959
-
p53 mutation with frequent novel codons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours
-
Crook, T., Brooks, L.A., Crossland, S., Osin, P., Barker, K.T., Waller, J., Philp, E., Smith, P.D., Yulug, I., Peto, J., Parker, G., Allday, M.J., Crompton, M.R. and Gusterson, B.A. (1998) p53 mutation with frequent novel codons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours. Oncogene 17:1681-1689.
-
(1998)
Oncogene
, vol.17
, pp. 1681-1689
-
-
Crook, T.1
Brooks, L.A.2
Crossland, S.3
Osin, P.4
Barker, K.T.5
Waller, J.6
Philp, E.7
Smith, P.D.8
Yulug, I.9
Peto, J.10
Parker, G.11
Allday, M.J.12
Crompton, M.R.13
Gusterson, B.A.14
-
18
-
-
0026530432
-
Clonal p53 mutation in primary cervical cancer: Association with human-papillomavirus-negative tumours
-
Crook, T., Wrede, D., Tidy, J.A., Mason, W.P., Evans, D.J. and Vousden, K.H. (1992) Clonal p53 mutation in primary cervical cancer: association with human-papillomavirus-negative tumours. Lancet 339:1070-1073.
-
(1992)
Lancet
, vol.339
, pp. 1070-1073
-
-
Crook, T.1
Wrede, D.2
Tidy, J.A.3
Mason, W.P.4
Evans, D.J.5
Vousden, K.H.6
-
19
-
-
0037022606
-
Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function
-
de Vries, A., Flores, E.R., Miranda, B., Hsieh, H.M., van Oostrom, C.T., Sage, J. and Jacks, T. (2002) Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function. Proc Natl Acad Sci USA 99:2948-2953.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2948-2953
-
-
De Vries, A.1
Flores, E.R.2
Miranda, B.3
Hsieh, H.M.4
Van Oostrom, C.T.5
Sage, J.6
Jacks, T.7
-
20
-
-
0032951530
-
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells
-
Di Como, C.J., Gaiddon, C. and Prives, C. (1999) p73 function is inhibited by tumor-derived p53 mutants in mammalian cells. Mol Cell Biol 19:1438-1449.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1438-1449
-
-
Di Como, C.J.1
Gaiddon, C.2
Prives, C.3
-
21
-
-
0032516219
-
Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay
-
Di Como, C.J. and Prives, C. (1998) Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay. Oncogene 16:2527-2539.
-
(1998)
Oncogene
, vol.16
, pp. 2527-2539
-
-
Di Como, C.J.1
Prives, C.2
-
22
-
-
0027210981
-
Gain of function mutations in p53
-
Dittmer, D., Pati, S., Zambetti, G., Chu, S., Teresky, A.K., Moore, M., Finlay, C. and Levine, A.J. (1993) Gain of function mutations in p53. Nat Genet 4:42-46.
-
(1993)
Nat Genet
, vol.4
, pp. 42-46
-
-
Dittmer, D.1
Pati, S.2
Zambetti, G.3
Chu, S.4
Teresky, A.K.5
Moore, M.6
Finlay, C.7
Levine, A.J.8
-
23
-
-
0034252667
-
Improving the detection of p53 mutations in breast cancer by use of the FASAY, a functional assay
-
Duddy, P.M., Hanby, A.M., Barnes, D.M. and Camplejohn, R.S. (2000) Improving the detection of p53 mutations in breast cancer by use of the FASAY, a functional assay. J Mol Diagn 2:139-144.
-
(2000)
J Mol Diagn
, vol.2
, pp. 139-144
-
-
Duddy, P.M.1
Hanby, A.M.2
Barnes, D.M.3
Camplejohn, R.S.4
-
24
-
-
0026849821
-
Definition of a consensus binding site for p53
-
el-Deiry, W.S., Kern, S.E., Pietenpol, J.A., Kinzler, K.W. and Vogelstein, B. (1992) Definition of a consensus binding site for p53. Nat Genet 1:45-49.
-
(1992)
Nat Genet
, vol.1
, pp. 45-49
-
-
Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler, K.W.4
Vogelstein, B.5
-
25
-
-
0026770424
-
Wild-type p53 activates transcription in vitro
-
Farmer, G., Bargonetti, J., Zhu, H., Friedman, P., Prywes, R. and Prives, C. (1992) Wild-type p53 activates transcription in vitro. Nature 358:83-86.
-
(1992)
Nature
, vol.358
, pp. 83-86
-
-
Farmer, G.1
Bargonetti, J.2
Zhu, H.3
Friedman, P.4
Prywes, R.5
Prives, C.6
-
26
-
-
0025024469
-
Presence of a potent transcription activating sequence in the p53 protein
-
Fields, S. and Jang, S.K. (1990) Presence of a potent transcription activating sequence in the p53 protein. Science 249:1046-1049.
-
(1990)
Science
, vol.249
, pp. 1046-1049
-
-
Fields, S.1
Jang, S.K.2
-
27
-
-
0018348464
-
Length-independent separation of DNA restriction fragments in two-dimensional gel electrophoresis
-
Fischer, S.G. and Lerman, L.S. (1979) Length-independent separation of DNA restriction fragments in two-dimensional gel electrophoresis. Cell 16:191-200.
-
(1979)
Cell
, vol.16
, pp. 191-200
-
-
Fischer, S.G.1
Lerman, L.S.2
-
28
-
-
0029043805
-
A simple p53 functional assay for screening cell lines, blood, and tumors
-
Flaman, J.M., Frebourg, T., Moreau, V., Charbonnier, F., Martin, C., Chappuis, P., Sappino, A.P., Limacher, I.M., Bron, L., Benhattar, J., Tada, M., Meir, E.G.V., Estreicher, A. and Iggo, R.D. (1995) A simple p53 functional assay for screening cell lines, blood, and tumors. Proc Natl Acad Sci USA 92:3963-3967.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3963-3967
-
-
Flaman, J.M.1
Frebourg, T.2
Moreau, V.3
Charbonnier, F.4
Martin, C.5
Chappuis, P.6
Sappino, A.P.7
Limacher, I.M.8
Bron, L.9
Benhattar, J.10
Tada, M.11
Meir, E.G.V.12
Estreicher, A.13
Iggo, R.D.14
-
29
-
-
0028029392
-
A rapid PCR fidelity assay
-
Flaman, J.M., Frebourg, T., Moreau, V., Charbonnier, F., Martin, C., Ishioka, C., Friend, S.H. and Iggo, R. (1994) A rapid PCR fidelity assay. Nucleic Acids Res 22:3259-3260.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 3259-3260
-
-
Flaman, J.M.1
Frebourg, T.2
Moreau, V.3
Charbonnier, F.4
Martin, C.5
Ishioka, C.6
Friend, S.H.7
Iggo, R.8
-
30
-
-
0032510341
-
Identification of human p53 mutations with differential effects on the bax and p21 promoters using functional assays in yeast
-
Flaman, J.M., Robert, V., Lenglet, S., Moreau, V., Iggo, R. and Frebourg, T. (1998) Identification of human p53 mutations with differential effects on the bax and p21 promoters using functional assays in yeast. Oncogene 16:1369-1372.
-
(1998)
Oncogene
, vol.16
, pp. 1369-1372
-
-
Flaman, J.M.1
Robert, V.2
Lenglet, S.3
Moreau, V.4
Iggo, R.5
Frebourg, T.6
-
31
-
-
0030030975
-
The human tumour suppressor gene p53 is alternatively spliced in normal cells
-
Flaman, J.M., Waridel, F., Estreicher, A., Vannier, A., Limacher, J.M., Gilbert, D., Iggo, R. and Frebourg, T. (1996) The human tumour suppressor gene p53 is alternatively spliced in normal cells. Oncogene 12:813-818.
-
(1996)
Oncogene
, vol.12
, pp. 813-818
-
-
Flaman, J.M.1
Waridel, F.2
Estreicher, A.3
Vannier, A.4
Limacher, J.M.5
Gilbert, D.6
Iggo, R.7
Frebourg, T.8
-
32
-
-
0026772127
-
Germline mutations of the p53 tumor suppressor gene in patients with high risk for cancer inactivate the p53 protein
-
Frebourg, T., Kassel, J., Lam, K.T., Gryka, M.A., Barbier, N., Andersen, T.I., Borresen, A.L. and Friend, S.H. (1992) Germline mutations of the p53 tumor suppressor gene in patients with high risk for cancer inactivate the p53 protein. Proc Natl Acad Sci USA 89:6413-6417.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6413-6417
-
-
Frebourg, T.1
Kassel, J.2
Lam, K.T.3
Gryka, M.A.4
Barbier, N.5
Andersen, T.I.6
Borresen, A.L.7
Friend, S.H.8
-
33
-
-
0029783722
-
A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
-
Friedlander, P., Haupt, Y., Prives, C. and Oren, M. (1996a) A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis. Mol Cell Biol 16:4961-4971.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4961-4971
-
-
Friedlander, P.1
Haupt, Y.2
Prives, C.3
Oren, M.4
-
34
-
-
0029815092
-
Regulation of mutant p53 temperature-sensitive DNA binding
-
Friedlander, P., Legros, Y., Soussi, T. and Prives, C. (1996b) Regulation of mutant p53 temperature-sensitive DNA binding. J Biol Chem 271:25468-25478.
-
(1996)
J Biol Chem
, vol.271
, pp. 25468-25478
-
-
Friedlander, P.1
Legros, Y.2
Soussi, T.3
Prives, C.4
-
35
-
-
0035131701
-
A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain
-
Gaiddon, C., Lokshin, M., Ahn, J., Zhang, T. and Prives, C. (2001) A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain. Mol Cell Biol 21:1874-1887.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1874-1887
-
-
Gaiddon, C.1
Lokshin, M.2
Ahn, J.3
Zhang, T.4
Prives, C.5
-
36
-
-
0025975701
-
Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport
-
Gannon, J.V. and Lane, D.P. (1991) Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport. Nature 349:802-806.
-
(1991)
Nature
, vol.349
, pp. 802-806
-
-
Gannon, J.V.1
Lane, D.P.2
-
37
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt, M.S., Bennett, W.P., Hollstein, M. and Harris, C.C. (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878.
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
38
-
-
0035872462
-
TP53 mutations in breast cancer associated with BRCA1 or BRCA2 germ-line mutations: Distinctive spectrum and structural distribution
-
Greenblatt, M.S., Chappuis, P.O., Bond, J.P., Hamel, N. and Foulkes, W.D. (2001) TP53 mutations in breast cancer associated with BRCA1 or BRCA2 germ-line mutations: distinctive spectrum and structural distribution. Cancer Res 61:4092-4097.
-
(2001)
Cancer Res
, vol.61
, pp. 4092-4097
-
-
Greenblatt, M.S.1
Chappuis, P.O.2
Bond, J.P.3
Hamel, N.4
Foulkes, W.D.5
-
39
-
-
0037432773
-
Polyubiquitination of p53 by a ubiquitin ligase activity of p300
-
Grossmann, S.R., Deato, M.E., Brignone, C., Chan, H.M., Kung, A.L., Tagami, H., Nakatani, Y. and Livingston, D.M. (2003) Polyubiquitination of p53 by a ubiquitin ligase activity of p300. Science 300:342-344.
-
(2003)
Science
, vol.300
, pp. 342-344
-
-
Grossmann, S.R.1
Deato, M.E.2
Brignone, C.3
Chan, H.M.4
Kung, A.L.5
Tagami, H.6
Nakatani, Y.7
Livingston, D.M.8
-
40
-
-
0037205454
-
Mutual dependence of MDM2 and MDMX in their functional inactivation of p53
-
Gu, J., Kawai, H., Nie, L., Kitao, H., Wiederschain, D., Jochemsen, A.G., Parant, J., Lozano, G. and Yuan, Z.M. (2002) Mutual dependence of MDM2 and MDMX in their functional inactivation of p53. J Biol Chem 277:19251-19254.
-
(2002)
J Biol Chem
, vol.277
, pp. 19251-19254
-
-
Gu, J.1
Kawai, H.2
Nie, L.3
Kitao, H.4
Wiederschain, D.5
Jochemsen, A.G.6
Parant, J.7
Lozano, G.8
Yuan, Z.M.9
-
41
-
-
0033992478
-
p53 and human cancer: The first ten thousand mutations
-
Hainaut, P. and Hollstein, M. (2000) p53 and human cancer: the first ten thousand mutations. Adv Cancer Res 77:81-137.
-
(2000)
Adv Cancer Res
, vol.77
, pp. 81-137
-
-
Hainaut, P.1
Hollstein, M.2
-
42
-
-
0030752030
-
Database of p53 gene somatic mutations in human tumors and cell lines: Updated compilation and future prospects
-
Hainaut, P., Soussi, T., Shomer, B., Hollstein, M., Greenblatt, M., Hovig, E., Harris, C.C. and Montesano, R. (1997) Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects. Nucleic Acids Res 25:151-157.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 151-157
-
-
Hainaut, P.1
Soussi, T.2
Shomer, B.3
Hollstein, M.4
Greenblatt, M.5
Hovig, E.6
Harris, C.C.7
Montesano, R.8
-
43
-
-
0025085667
-
Different tumor-derived p53 mutants exhibit distinct biological activities
-
Halevy, O., Michalovitz, D. and Oren, M. (1990) Different tumor-derived p53 mutants exhibit distinct biological activities. Science 250:113-116.
-
(1990)
Science
, vol.250
, pp. 113-116
-
-
Halevy, O.1
Michalovitz, D.2
Oren, M.3
-
44
-
-
0029922621
-
p53 tumor suppressor gene: From the basic research laboratory to the clinic-an abridged historical perspective
-
Harris, C.C. (1996) p53 tumor suppressor gene: from the basic research laboratory to the clinic-an abridged historical perspective. Carcinogenesis 17:1187-1198.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1187-1198
-
-
Harris, C.C.1
-
45
-
-
0026207465
-
PCR-SSCP: A simple and sensitive method for detection of mutations in the genomic DNA
-
Hayashi, K. (1991) PCR-SSCP: a simple and sensitive method for detection of mutations in the genomic DNA. PCR Methods Appl 1:34-38.
-
(1991)
PCR Methods Appl
, vol.1
, pp. 34-38
-
-
Hayashi, K.1
-
46
-
-
0033376873
-
New approaches to understanding p53 gene tumor mutation spectra
-
Hollstein, M., Hergenhahn, M., Yang, Q., Bartsch, H., Wang, Z.Q. and Hainaut, P. (1999) New approaches to understanding p53 gene tumor mutation spectra. Mutat Res 431:199-209.
-
(1999)
Mutat Res
, vol.431
, pp. 199-209
-
-
Hollstein, M.1
Hergenhahn, M.2
Yang, Q.3
Bartsch, H.4
Wang, Z.Q.5
Hainaut, P.6
-
47
-
-
0025894713
-
p53 mutations in human cancers
-
Hollstein, M., Sidransky, D., Vogelstein, B. and Harris, C.C. (1991) p53 mutations in human cancers. Science 253:49-53.
-
(1991)
Science
, vol.253
, pp. 49-53
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.C.4
-
48
-
-
0026425686
-
Role of the human papillomaviruses in human cancer
-
Howley, P.M. (1991) Role of the human papillomaviruses in human cancer. Cancer Res 51:5019s-5022s.
-
(1991)
Cancer Res
, vol.51
, pp. 5019-5022
-
-
Howley, P.M.1
-
49
-
-
0030915448
-
Human BRCA1 inhibits growth in yeast: Potential use in diagnostic testing
-
Humphrey, J.S., Salim, A., Erdos, M.R., Coffins, F.S., Brody, L.C. and Klausner, R.D. (1997) Human BRCA1 inhibits growth in yeast: potential use in diagnostic testing. Proc Natl Acad Sci USA 94:5820-5825.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5820-5825
-
-
Humphrey, J.S.1
Salim, A.2
Erdos, M.R.3
Coffins, F.S.4
Brody, L.C.5
Klausner, R.D.6
-
50
-
-
0032530215
-
Molecular epidemiology of human cancer: Contribution of mutation spectra studies of tumor suppressor genes
-
Hussain, S.P. and Harris, C.C. (1998) Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes. Cancer Res 58:4023-4037.
-
(1998)
Cancer Res
, vol.58
, pp. 4023-4037
-
-
Hussain, S.P.1
Harris, C.C.2
-
51
-
-
0033083988
-
N-(2-chloroethyl)-N-nitrosourea tethered to lexitropsin induces minor groove lesions at the p53 cDNA that are more cytotoxic than mutagenic
-
Inga, A., Chen, F.X., Monti, P., Aprile, A., Campomenosi, P., Menichini, P., Ottaggio, L., Viaggi, S., Abbondandolo, A., Gold, B. and Fronza, G. (1999) N-(2-chloroethyl)-N-nitrosourea tethered to lexitropsin induces minor groove lesions at the p53 cDNA that are more cytotoxic than mutagenic. Cancer Res 59:689-695.
-
(1999)
Cancer Res
, vol.59
, pp. 689-695
-
-
Inga, A.1
Chen, F.X.2
Monti, P.3
Aprile, A.4
Campomenosi, P.5
Menichini, P.6
Ottaggio, L.7
Viaggi, S.8
Abbondandolo, A.9
Gold, B.10
Fronza, G.11
-
52
-
-
0031424868
-
Simple identification of dominant p53 mutants by a yeast functional assay
-
Inga, A., Cresta, S., Monti, P., Aprile, A., Scott, G., Abbondandolo, A., Iggo, R. and Fronza, G. (1997a) Simple identification of dominant p53 mutants by a yeast functional assay. Carcinogenesis 18:2019-2021.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2019-2021
-
-
Inga, A.1
Cresta, S.2
Monti, P.3
Aprile, A.4
Scott, G.5
Abbondandolo, A.6
Iggo, R.7
Fronza, G.8
-
53
-
-
0030934778
-
Determining mutational fingerprints at the human p53 locus with a yeast functional assay: A new tool for molecular epidemiology
-
Inga, A., Iannone, R., Monti, P., Molina, F., Bolognesi, M., Abbondandolo, A., Iggo, R. and Fronza, G. (1997b) Determining mutational fingerprints at the human p53 locus with a yeast functional assay: a new tool for molecular epidemiology. Oncogene 14:1307-1313.
-
(1997)
Oncogene
, vol.14
, pp. 1307-1313
-
-
Inga, A.1
Iannone, R.2
Monti, P.3
Molina, F.4
Bolognesi, M.5
Abbondandolo, A.6
Iggo, R.7
Fronza, G.8
-
54
-
-
0035945659
-
p53 mutants exhibiting enhanced transcriptional activation and altered promoter selectivity are revealed using a sensitive, yeast-based functional assay
-
Inga, A., Monti, P., Fronza, G., Darden, T. and Resnick, M.A. (2001) p53 mutants exhibiting enhanced transcriptional activation and altered promoter selectivity are revealed using a sensitive, yeast-based functional assay. Oncogene 20:501-513.
-
(2001)
Oncogene
, vol.20
, pp. 501-513
-
-
Inga, A.1
Monti, P.2
Fronza, G.3
Darden, T.4
Resnick, M.A.5
-
55
-
-
0031844522
-
Ultraviolet-light induced p53 mutational spectrum in yeast is indistinguishable from p53 mutations in human skin cancer
-
Inga, A., Scott, G., Monti, P., Aprile, A., Abbondandolo, A., Burns, P.A. and Fronza, G. (1998) Ultraviolet-light induced p53 mutational spectrum in yeast is indistinguishable from p53 mutations in human skin cancer. Carcinogenesis 19:741-746.
-
(1998)
Carcinogenesis
, vol.19
, pp. 741-746
-
-
Inga, A.1
Scott, G.2
Monti, P.3
Aprile, A.4
Abbondandolo, A.5
Burns, P.A.6
Fronza, G.7
-
56
-
-
0036892060
-
Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence
-
Inga, A., Storici, F., Darden, T.A. and Resnick, M.A. (2002) Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence. Mol Cell Biol 22:8612-8625.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8612-8625
-
-
Inga, A.1
Storici, F.2
Darden, T.A.3
Resnick, M.A.4
-
57
-
-
0032977124
-
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines
-
Ishii, N., Maier, D., Merlo, A., Tada, M., Sawamura, Y., Diserens, A.C. and Van Meir, E.G. (1999) Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines. Brain Pathol 9:469-479.
-
(1999)
Brain Pathol
, vol.9
, pp. 469-479
-
-
Ishii, N.1
Maier, D.2
Merlo, A.3
Tada, M.4
Sawamura, Y.5
Diserens, A.C.6
Van Meir, E.G.7
-
58
-
-
0028968361
-
A functional assay for heterozygous mutations in the GTPase activating protein related domain of the neurofibromatosis type 1 gene
-
Ishioka, C., Ballester, R., Engelstein, M., Vidal, M., Kassel, J., The, I., Bernards, A., Gusella, J.F. and Friend, S.H. (1995a) A functional assay for heterozygous mutations in the GTPase activating protein related domain of the neurofibromatosis type 1 gene. Oncogene 10:841-847.
-
(1995)
Oncogene
, vol.10
, pp. 841-847
-
-
Ishioka, C.1
Ballester, R.2
Engelstein, M.3
Vidal, M.4
Kassel, J.5
The, I.6
Bernards, A.7
Gusella, J.F.8
Friend, S.H.9
-
59
-
-
0029028352
-
Mutational analysis of the carboxy-terminal portion of p53 using both yeast and mammalian cell assays in vivo
-
Ishioka, C., Englert, C., Winge, P., Yan, Y.X., Engelstein, M. and Friend, S.H. (1995b) Mutational analysis of the carboxy-terminal portion of p53 using both yeast and mammalian cell assays in vivo. Oncogene 10:1485-1492.
-
(1995)
Oncogene
, vol.10
, pp. 1485-1492
-
-
Ishioka, C.1
Englert, C.2
Winge, P.3
Yan, Y.X.4
Engelstein, M.5
Friend, S.H.6
-
60
-
-
0027430658
-
Screening patients for heterozygous p53 mutations using a functional assay in yeast
-
Ishioka, C., Frebourg, T., Yan, Y.X., Vidal, M., Friend, S.H., Schmidt, S. and Iggo, R. (1993) Screening patients for heterozygous p53 mutations using a functional assay in yeast. Nat Genet 5:124-129.
-
(1993)
Nat Genet
, vol.5
, pp. 124-129
-
-
Ishioka, C.1
Frebourg, T.2
Yan, Y.X.3
Vidal, M.4
Friend, S.H.5
Schmidt, S.6
Iggo, R.7
-
61
-
-
12644303219
-
Detection of heterozygous truncating mutations in the BRCA1 and APC genes by using a rapid screening assay in yeast
-
Ishioka, C., Suzuki, T., FitzGerald, M., Krainer, M., Shimodaira, H., Shimada, A., Nomizu, T., Isselbacher, K.J., Haber, D. and Kanamaru, R. (1997) Detection of heterozygous truncating mutations in the BRCA1 and APC genes by using a rapid screening assay in yeast. Proc Natl Acad Sci USA 94:2449-2453.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2449-2453
-
-
Ishioka, C.1
Suzuki, T.2
Fitzgerald, M.3
Krainer, M.4
Shimodaira, H.5
Shimada, A.6
Nomizu, T.7
Isselbacher, K.J.8
Haber, D.9
Kanamaru, R.10
-
62
-
-
0033963335
-
MdmX protects p53 from Mdm2-mediated degradation
-
Jackson, M.W. and Berberich, S.J. (2000) MdmX protects p53 from Mdm2-mediated degradation. Mol Cell Biol 20:1001-1007.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1001-1007
-
-
Jackson, M.W.1
Berberich, S.J.2
-
63
-
-
0030817069
-
Screening the p53 status of human cell lines using a yeast functional assay
-
Jia, L.Q., Osada, M., Ishioka, C., Gamo, M., Ikawa, S., Suzuki, T., Shimodaira, H., Niitani, T., Kudo, T., Akiyama, M., Kimura, N., Matsuo, M., Mizusawa, H., Tanaka, N., Koyama, H., Namba, M., Kanamaru, R. and Kuroki, T. (1997) Screening the p53 status of human cell lines using a yeast functional assay. Mol Carcinogen 19:243-253.
-
(1997)
Mol Carcinogen
, vol.19
, pp. 243-253
-
-
Jia, L.Q.1
Osada, M.2
Ishioka, C.3
Gamo, M.4
Ikawa, S.5
Suzuki, T.6
Shimodaira, H.7
Niitani, T.8
Kudo, T.9
Akiyama, M.10
Kimura, N.11
Matsuo, M.12
Mizusawa, H.13
Tanaka, N.14
Koyama, H.15
Namba, M.16
Kanamaru, R.17
Kuroki, T.18
-
64
-
-
0032487920
-
Tumour associated mutants of p53 can inhibit transcriptional activity of p53 without heterooligomerization
-
Joers, A., Kristjuhan, A., Kadaja, L. and Maimets, T. (1998) Tumour associated mutants of p53 can inhibit transcriptional activity of p53 without heterooligomerization. Oncogene 17:2351-2358.
-
(1998)
Oncogene
, vol.17
, pp. 2351-2358
-
-
Joers, A.1
Kristjuhan, A.2
Kadaja, L.3
Maimets, T.4
-
65
-
-
0028834902
-
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
-
Jones, S.N., Roe, A.E., Donehower, L.A. and Bradley, A. (1995) Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature 378:206-208.
-
(1995)
Nature
, vol.378
, pp. 206-208
-
-
Jones, S.N.1
Roe, A.E.2
Donehower, L.A.3
Bradley, A.4
-
66
-
-
0031564954
-
p73 is a simian p53-related protein that can induce apoptosis
-
Jost, C.A., Marin, M.C. and Kaelin, W.G., Jr. (1997) p73 is a simian p53-related protein that can induce apoptosis. Nature 389:191-194.
-
(1997)
Nature
, vol.389
, pp. 191-194
-
-
Jost, C.A.1
Marin, M.C.2
Kaelin Jr., W.G.3
-
67
-
-
0030812331
-
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
-
Kaghad, M., Bonnet, H., Yang, A., Creancier, L., Biscan, J.C., Valent, A., Minty, A., Chalon, P., Lelias, J.M., Dumont, X., Ferrara, P., McKeon, F. and Caput, D. (1997) Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 90:809-819.
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
Creancier, L.4
Biscan, J.C.5
Valent, A.6
Minty, A.7
Chalon, P.8
Lelias, J.M.9
Dumont, X.10
Ferrara, P.11
McKeon, F.12
Caput, D.13
-
68
-
-
0032493350
-
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
-
Kamijo, T., Weber, J.D., Zambetti, G., Zindy, F., Roussel, M.F. and Sherr, C.J. (1998) Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. Proc Natl Acad Sci USA 95:8292-8297.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8292-8297
-
-
Kamijo, T.1
Weber, J.D.2
Zambetti, G.3
Zindy, F.4
Roussel, M.F.5
Sherr, C.J.6
-
69
-
-
0030694492
-
High frequency of p53 mutations in human oral epithelial dysplasia and primary squamous cell carcinoma detected by yeast functional assay
-
Kashiwazaki, H., Tonoki, H., Tada, M., Chiba, I., Shindoh, M., Totsuka, Y., Iggo, R. and Moriuchi, T. (1997) High frequency of p53 mutations in human oral epithelial dysplasia and primary squamous cell carcinoma detected by yeast functional assay. Oncogene 15:2667-2674.
-
(1997)
Oncogene
, vol.15
, pp. 2667-2674
-
-
Kashiwazaki, H.1
Tonoki, H.2
Tada, M.3
Chiba, I.4
Shindoh, M.5
Totsuka, Y.6
Iggo, R.7
Moriuchi, T.8
-
70
-
-
0037816165
-
Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis
-
Kato, S., Han, S.Y., Liu, W., Otsuka, K., Shibata, H., Kanamaru, R. and Ishioka, C. (2003) Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis. Proc Natl Acad Sci USA 100:8424-8429.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8424-8429
-
-
Kato, S.1
Han, S.Y.2
Liu, W.3
Otsuka, K.4
Shibata, H.5
Kanamaru, R.6
Ishioka, C.7
-
71
-
-
0035153387
-
Regulation of telomerase activity by alternate splicing of human telomerase reverse transcriptase mRNA in a subset of neuroblastomas
-
Krams, M., Claviez, A., Heidorn, K., Krupp, G., Parwaresch, R., Harms, D. and Rudolph, P. (2001) Regulation of telomerase activity by alternate splicing of human telomerase reverse transcriptase mRNA in a subset of neuroblastomas. Am J Pathol 159:1925-1932.
-
(2001)
Am J Pathol
, vol.159
, pp. 1925-1932
-
-
Krams, M.1
Claviez, A.2
Heidorn, K.3
Krupp, G.4
Parwaresch, R.5
Harms, D.6
Rudolph, P.7
-
72
-
-
0028124528
-
p53 and human cancers
-
Lane, D.P. (1994) p53 and human cancers. Br Med Bull 50:582-599.
-
(1994)
Br Med Bull
, vol.50
, pp. 582-599
-
-
Lane, D.P.1
-
73
-
-
0018348655
-
T antigen is bound to a host protein in SV40-transformed cells
-
Lane, D.P. and Crawford, L.V. (1979) T antigen is bound to a host protein in SV40-transformed cells. Nature 278:261-263.
-
(1979)
Nature
, vol.278
, pp. 261-263
-
-
Lane, D.P.1
Crawford, L.V.2
-
74
-
-
0037459377
-
Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation
-
Leng, R.P., Lin, Y., Ma, W., Wu, H., Lemmers, B., Chung, S., Parant, J.M., Lozano, G., Hakem, R. and Benchimol, S. (2003) Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell 112:779-791.
-
(2003)
Cell
, vol.112
, pp. 779-791
-
-
Leng, R.P.1
Lin, Y.2
Ma, W.3
Wu, H.4
Lemmers, B.5
Chung, S.6
Parant, J.M.7
Lozano, G.8
Hakem, R.9
Benchimol, S.10
-
75
-
-
0348134742
-
Mono- Versus polyubiquitination: Differential control of p53 fate by Mdm2
-
Li, M., Brooks, C.L., Wu-Baer, F., Chen, D., Baer, R. and Gu, W. (2003) Mono- versus polyubiquitination: differential control of p53 fate by Mdm2. Science 302:1972-1975.
-
(2003)
Science
, vol.302
, pp. 1972-1975
-
-
Li, M.1
Brooks, C.L.2
Wu-Baer, F.3
Chen, D.4
Baer, R.5
Gu, W.6
-
76
-
-
0037061508
-
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
-
Li, M., Chen, D., Shiloh, A., Luo, J., Nikolaev, A.Y., Ruin, J. and Gu, W. (2002) Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature 416:648-653.
-
(2002)
Nature
, vol.416
, pp. 648-653
-
-
Li, M.1
Chen, D.2
Shiloh, A.3
Luo, J.4
Nikolaev, A.Y.5
Ruin, J.6
Gu, W.7
-
77
-
-
0032584666
-
Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein
-
Liang, S.H., Hong, D. and Clarke, M.F. (1998) Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein. J Biol Chem 273:19817-19821.
-
(1998)
J Biol Chem
, vol.273
, pp. 19817-19821
-
-
Liang, S.H.1
Hong, D.2
Clarke, M.F.3
-
78
-
-
0028303752
-
Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
-
Lin, J., Chen, J., Elenbaas, B. and Levine, A.J. (1994) Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. Genes Dev 8:1235-1246.
-
(1994)
Genes Dev
, vol.8
, pp. 1235-1246
-
-
Lin, J.1
Chen, J.2
Elenbaas, B.3
Levine, A.J.4
-
79
-
-
0018760324
-
Characterization of a 54 K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
-
Linzer, D.I. and Levine, A.J. (1979) Characterization of a 54 K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell 17:43-52.
-
(1979)
Cell
, vol.17
, pp. 43-52
-
-
Linzer, D.I.1
Levine, A.J.2
-
80
-
-
0030926817
-
Two functional assays employed to detect an unusual mutation in the oligomerisation domain of p53 in a Li-Fraumeni like family
-
Lomax, M.E., Barnes, D.M., Gilchrist, R., Picksley, S.M., Varley, J.M. and Camplejohn, R.S. (1997) Two functional assays employed to detect an unusual mutation in the oligomerisation domain of p53 in a Li-Fraumeni like family. Oncogene 14:1869-1874.
-
(1997)
Oncogene
, vol.14
, pp. 1869-1874
-
-
Lomax, M.E.1
Barnes, D.M.2
Gilchrist, R.3
Picksley, S.M.4
Varley, J.M.5
Camplejohn, R.S.6
-
81
-
-
0029742781
-
Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function
-
Ludwig, R.L., Bates, S. and Vousden, K.H. (1996) Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function. Mol Cell Biol 16:4952-4960.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4952-4960
-
-
Ludwig, R.L.1
Bates, S.2
Vousden, K.H.3
-
82
-
-
0027215222
-
Structure-specific endonucleolytic cleavage of nucleic acids by eubacterial DNA polymerases
-
Lyamichev, V., Brow, M.A. and Dahlberg, I.E. (1993) Structure-specific endonucleolytic cleavage of nucleic acids by eubacterial DNA polymerases. Science 260:778-783.
-
(1993)
Science
, vol.260
, pp. 778-783
-
-
Lyamichev, V.1
Brow, M.A.2
Dahlberg, I.E.3
-
83
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin, D., Li, F.P., Strong, L.C., Fraumeni, J.F., Jr., Nelson, C.E., Kim, D.H., Kassel, J., Gryka, M.A., Bischoff, F.Z., Tainsky, M.A. and Friend, S.H. (1990) Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250:1233-1238.
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
Fraumeni Jr., J.F.4
Nelson, C.E.5
Kim, D.H.6
Kassel, J.7
Gryka, M.A.8
Bischoff, F.Z.9
Tainsky, M.A.10
Friend, S.H.11
-
84
-
-
0034717014
-
Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
-
Marchenko, N.D., Zaika, A. and Moll, U.M. (2000) Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem 275:16202-16212.
-
(2000)
J Biol Chem
, vol.275
, pp. 16202-16212
-
-
Marchenko, N.D.1
Zaika, A.2
Moll, U.M.3
-
85
-
-
0026501561
-
Temperature-sensitive mutants of p53 associated with human carcinoma of the lung
-
Medcalf, E.A., Takahashi, T., Chiba, I., Minna, J. and Milner, J. (1992) Temperature-sensitive mutants of p53 associated with human carcinoma of the lung. Oncogene 7:71-76.
-
(1992)
Oncogene
, vol.7
, pp. 71-76
-
-
Medcalf, E.A.1
Takahashi, T.2
Chiba, I.3
Minna, J.4
Milner, J.5
-
86
-
-
17744370913
-
Evaluation of methods to detect p53 mutations in ovarian cancer
-
Meinhold-Heerlein, I., Ninci, E., Ikenberg, H., Brandstetter, T., Ihling, C., Schwenk, I., Straub, A., Schmitt, B., Bettendorf, H., Iggo, R. and Bauknecht, T. (2001) Evaluation of methods to detect p53 mutations in ovarian cancer. Oncology 60:176-188.
-
(2001)
Oncology
, vol.60
, pp. 176-188
-
-
Meinhold-Heerlein, I.1
Ninci, E.2
Ikenberg, H.3
Brandstetter, T.4
Ihling, C.5
Schwenk, I.6
Straub, A.7
Schmitt, B.8
Bettendorf, H.9
Iggo, R.10
Bauknecht, T.11
-
87
-
-
0027079358
-
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein
-
Mietz, J.A., Unger, T., Huibregtse, J.M. and Howley, P.M. (1992) The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J 11:5013-5020.
-
(1992)
EMBO J
, vol.11
, pp. 5013-5020
-
-
Mietz, J.A.1
Unger, T.2
Huibregtse, J.M.3
Howley, P.M.4
-
88
-
-
0037349289
-
p53 has a direct apoptogenic role at the mitichondria
-
Mihara, M., Erster, S., Zaika, A., Petrenko, O., Chittenden, T., Pancoska, P. and Moll, U.M. (2003) p53 has a direct apoptogenic role at the mitichondria. Mol Cell 11:577-590.
-
(2003)
Mol Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
Moll, U.M.7
-
89
-
-
0029049828
-
Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors
-
Moll, U.M., LaQuaglia, M., Benard, J. and Riou, G. (1995) Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc Natl Acad Sci USA 92:4407-4411.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4407-4411
-
-
Moll, U.M.1
Laquaglia, M.2
Benard, J.3
Riou, G.4
-
90
-
-
0030048389
-
Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage
-
Moll, U.M., Ostermeyer, A.G., Haladay, R., Winkfleld, B., Frazier, M. and Zambetti, G. (1996) Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage. Mol Cell Biol 16:1126-1137.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1126-1137
-
-
Moll, U.M.1
Ostermeyer, A.G.2
Haladay, R.3
Winkfleld, B.4
Frazier, M.5
Zambetti, G.6
-
91
-
-
0026694826
-
Two distinct mechanisms alter p53 in breast cancer: Mutation and nuclear exclusion
-
Moll, U.M., Riou, G. and Levine, A.J. (1992) Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc Natl Acad Sci USA 89:7262-7266.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7262-7266
-
-
Moll, U.M.1
Riou, G.2
Levine, A.J.3
-
92
-
-
0035970721
-
Nuclear and mitochondrial apoptotic pathways of p53
-
Moll, U.M. and Zaika, A. (2001) Nuclear and mitochondrial apoptotic pathways of p53. FEBS Lett 493:65-69.
-
(2001)
FEBS Lett
, vol.493
, pp. 65-69
-
-
Moll, U.M.1
Zaika, A.2
-
93
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
Momand, J., Zambetti, G.P., Olson, D.C., George, D. and Levine, A.J. (1992) The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69:1237-1245.
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
94
-
-
0028823020
-
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
-
Montes de Oca Luna, R., Wagner, D.S. and Lozano, G. (1995) Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 378:203-206.
-
(1995)
Nature
, vol.378
, pp. 203-206
-
-
Montes De Oca Luna, R.1
Wagner, D.S.2
Lozano, G.3
-
95
-
-
0041353453
-
Characterization of the p53 mutants ability to inhibit p73 beta transactivation using a yeast-based functional assay
-
Monti, P., Campomenosi, P., Ciribilli, Y., Iannone, R., Aprile, A., Inga, A., Tada, M., Menichini, P., Abbondandolo, A. and Fronza, G. (2003) Characterization of the p53 mutants ability to inhibit p73 beta transactivation using a yeast-based functional assay. Oncogene 22:5252-5260.
-
(2003)
Oncogene
, vol.22
, pp. 5252-5260
-
-
Monti, P.1
Campomenosi, P.2
Ciribilli, Y.3
Iannone, R.4
Aprile, A.5
Inga, A.6
Tada, M.7
Menichini, P.8
Abbondandolo, A.9
Fronza, G.10
-
96
-
-
85047695905
-
Tumour p53 mutations exhibit promoter selective dominance over wild type p53
-
Monti, P., Campomenosi, P., Ciribilli, Y., Iannone, R., Inga, A., Abbondandolo, A., Resnick, M.A. and Fronza, G. (2002) Tumour p53 mutations exhibit promoter selective dominance over wild type p53. Oncogene 21:1641-1648.
-
(2002)
Oncogene
, vol.21
, pp. 1641-1648
-
-
Monti, P.1
Campomenosi, P.2
Ciribilli, Y.3
Iannone, R.4
Inga, A.5
Abbondandolo, A.6
Resnick, M.A.7
Fronza, G.8
-
97
-
-
0031004763
-
UV-induced mutagenesis of human p53 in a vector replicated in Sacharomyces cerevisiae
-
Moshinsky, D.J. and Wogan, G.N. (1997) UV-induced mutagenesis of human p53 in a vector replicated in Sacharomyces cerevisiae. Proc Natl Acad Sci USA 94:2266-2271.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2266-2271
-
-
Moshinsky, D.J.1
Wogan, G.N.2
-
98
-
-
0025935611
-
Detection of aberrations of the p53 alleles and the gene transcript in human tumor cell lines by single-strand conformation polymorphism analysis
-
Murakami, Y., Hayashi, K. and Sekiya, T. (1991) Detection of aberrations of the p53 alleles and the gene transcript in human tumor cell lines by single-strand conformation polymorphism analysis. Cancer Res 51:3356-3361.
-
(1991)
Cancer Res
, vol.51
, pp. 3356-3361
-
-
Murakami, Y.1
Hayashi, K.2
Sekiya, T.3
-
99
-
-
0024387728
-
Mutations in the p53 gene occur in diverse human tumour types
-
Nigro, J.M., Baker, S.J., Preisinger, A.C., Jessup, J.M., Hostetter, R., Cleary, K., Bigner, S.H., Davidson, N., Baylin, S., Devilee, P., Glover, T., Collins, F.S., Weslon, A., Modali, R., Hartus, C.C. and Vogelstein, B. (1989) Mutations in the p53 gene occur in diverse human tumour types. Nature 342:705-708.
-
(1989)
Nature
, vol.342
, pp. 705-708
-
-
Nigro, J.M.1
Baker, S.J.2
Preisinger, A.C.3
Jessup, J.M.4
Hostetter, R.5
Cleary, K.6
Bigner, S.H.7
Davidson, N.8
Baylin, S.9
Devilee, P.10
Glover, T.11
Collins, F.S.12
Weslon, A.13
Modali, R.14
Hartus, C.C.15
Vogelstein, B.16
-
100
-
-
0037428078
-
Parc: A cytoplasmic anchor for p53
-
Nikolaev, A.Y., Li, M., Puskas, N., Qin, J. and Gu, W. (2003) Parc: a cytoplasmic anchor for p53. Cell 112:29-40.
-
(2003)
Cell
, vol.112
, pp. 29-40
-
-
Nikolaev, A.Y.1
Li, M.2
Puskas, N.3
Qin, J.4
Gu, W.5
-
101
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner, J.D., Kinzler, K.W., Meltzer, P.S., George, D.L. and Vogelstein, B. (1992) Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 358:80-83.
-
(1992)
Nature
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
102
-
-
0036258111
-
The IARC TP53 database: New online mutation analysis and recommendations to users
-
Olivier, M., Eeles, R., Hollstein, M., Khan, M.A., Harris, C.C. and Hainaut, P. (2002) The IARC TP53 database: new online mutation analysis and recommendations to users. Hum Mutat 19:607-614.
-
(2002)
Hum Mutat
, vol.19
, pp. 607-614
-
-
Olivier, M.1
Eeles, R.2
Hollstein, M.3
Khan, M.A.4
Harris, C.C.5
Hainaut, P.6
-
103
-
-
1842862755
-
TP53 mutation spectra and load: A tool for generating hypotheses on the etiology of cancer
-
Olivier, M., Hussain, S.P., Caron de Fromentel, C., Hainaut, P. and Harris, C.C. (2004) TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer. IARC Sci Publ 157:247-270.
-
(2004)
IARC Sci Publ
, vol.157
, pp. 247-270
-
-
Olivier, M.1
Hussain, S.P.2
Caron De Fromentel, C.3
Hainaut, P.4
Harris, C.C.5
-
105
-
-
1542751000
-
High frequency of temperature-sensitive mutations of p53 tumor suppressor in acute myeloid leukemia revealed by functional assay in yeast
-
Pavlova, S., Mayer, J., Koukalova, H. and Smardova, J. (2003) High frequency of temperature-sensitive mutations of p53 tumor suppressor in acute myeloid leukemia revealed by functional assay in yeast. Int J Oncol 23:121-131.
-
(2003)
Int J Oncol
, vol.23
, pp. 121-131
-
-
Pavlova, S.1
Mayer, J.2
Koukalova, H.3
Smardova, J.4
-
106
-
-
0030044421
-
Different p53 mutations produce distinct effects on the ability of colon carcinoma cells to become blocked at the G1/S boundary after irradiation
-
Pocard, M., Chevillard, S., Villaudy, J., Poupon, M.F., Dutrillaux, B. and Remvikos, Y. (1996) Different p53 mutations produce distinct effects on the ability of colon carcinoma cells to become blocked at the G1/S boundary after irradiation. Oncogene 12:875-882.
-
(1996)
Oncogene
, vol.12
, pp. 875-882
-
-
Pocard, M.1
Chevillard, S.2
Villaudy, J.3
Poupon, M.F.4
Dutrillaux, B.5
Remvikos, Y.6
-
107
-
-
0032549704
-
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Pomerantz, J., Schreiber-Agus, N., Liegeois, N.J., Silverman, A., Alland, L., Chin, L., Poles, J., Chen, K., Orloj, I., Lee, H.W., Kordon-Cardo, C. and DePinho, R.A. (1998) The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 92:713-723.
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Poles, J.7
Chen, K.8
Orloj, I.9
Lee, H.W.10
Kordon-Cardo, C.11
DePinho, R.A.12
-
108
-
-
0035966316
-
Why is p53 acetylated?
-
Prives, C. and Manley, J.L. (2001) Why is p53 acetylated? Cell 107:815-818.
-
(2001)
Cell
, vol.107
, pp. 815-818
-
-
Prives, C.1
Manley, J.L.2
-
109
-
-
0037038699
-
Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding sites
-
Qian, H., Wang, T., Naumovski, L., Lopez, C.D. and Brachmann, R.K. (2002) Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding sites. Oncogene 21:7901-7911.
-
(2002)
Oncogene
, vol.21
, pp. 7901-7911
-
-
Qian, H.1
Wang, T.2
Naumovski, L.3
Lopez, C.D.4
Brachmann, R.K.5
-
110
-
-
0035266128
-
Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53
-
Ramos, Y.F., Stad, R., Attema, J., Peltenburg, L.T., van der Eb, A.J. and Jochemsen, A.G. (2001) Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53. Cancer Res 61:1839-1842.
-
(2001)
Cancer Res
, vol.61
, pp. 1839-1842
-
-
Ramos, Y.F.1
Stad, R.2
Attema, J.3
Peltenburg, L.T.4
Van Der Eb, A.J.5
Jochemsen, A.G.6
-
111
-
-
0025193635
-
Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene
-
Raycroft, L., Wu, H.Y. and Lozano, G. (1990) Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene. Science 249:1049-1051.
-
(1990)
Science
, vol.249
, pp. 1049-1051
-
-
Raycroft, L.1
Wu, H.Y.2
Lozano, G.3
-
112
-
-
0027196974
-
Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations
-
Reifenberger, G., Liu, L., Ichimura, K., Schmidt, E.E. and Collins, V.P. (1993) Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. Cancer Res 53:2736-2739.
-
(1993)
Cancer Res
, vol.53
, pp. 2736-2739
-
-
Reifenberger, G.1
Liu, L.2
Ichimura, K.3
Schmidt, E.E.4
Collins, V.P.5
-
113
-
-
0042692855
-
Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity
-
Resnick, M.A. and Inga, A. (2003) Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity. Proc Natl Acad Sci USA 100:9934-9939.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9934-9939
-
-
Resnick, M.A.1
Inga, A.2
-
114
-
-
0035979262
-
An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma
-
Ribeiro, R.C., Sandrini, F., Figueiredo, B., Zambetti, G.P., Michalkiewicz, E., Lafferty, A.R., DeLacerda, L., Rabin, M., Cadwell, C., Sampaio, G., Cat, I., Stratakis, C.A. and Sandrini, R. (2001) An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma. Proc Natl Acad Sci USA 98:9330-9335.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9330-9335
-
-
Ribeiro, R.C.1
Sandrini, F.2
Figueiredo, B.3
Zambetti, G.P.4
Michalkiewicz, E.5
Lafferty, A.R.6
Delacerda, L.7
Rabin, M.8
Cadwell, C.9
Sampaio, G.10
Cat, I.11
Stratakis, C.A.12
Sandrini, R.13
-
115
-
-
0030021748
-
Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant
-
Rowan, S., Ludwig, R.L., Haupt, Y., Bates, S., Lu, X., Oren, M. and Vousden, K.H. (1996) Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant. EMBO J 15:827-838.
-
(1996)
EMBO J
, vol.15
, pp. 827-838
-
-
Rowan, S.1
Ludwig, R.L.2
Haupt, Y.3
Bates, S.4
Lu, X.5
Oren, M.6
Vousden, K.H.7
-
116
-
-
0027156827
-
Analysis of a protein-binding domain of p53
-
Ruppert, J. and Stillmann, B. (1993) Analysis of a protein-binding domain of p53. Mol Cell Biol 13:3811-3820.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 3811-3820
-
-
Ruppert, J.1
Stillmann, B.2
-
117
-
-
17944379798
-
ASPP proteins specifically stimulate the apoptotic function of p53
-
Samuels-Lev, Y., O'Connor, D., Bergamaschi, D., Trigiante, G., Hsieh, J., Zhong, S., Campargue, I., Naumovski, L., Crook, T. and Lu, X. (2001) ASPP proteins specifically stimulate the apoptotic function of p53. Mol Cell 8:781-794.
-
(2001)
Mol Cell
, vol.8
, pp. 781-794
-
-
Samuels-Lev, Y.1
O'Connor, D.2
Bergamaschi, D.3
Trigiante, G.4
Hsieh, J.5
Zhong, S.6
Campargue, I.7
Naumovski, L.8
Crook, T.9
Lu, X.10
-
118
-
-
0020079972
-
Adenovirus E1b-58 kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells
-
Sarnow, P., Ho, Y.S., Williams, J. and Levine, A.J. (1982) Adenovirus E1b-58 kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells. Cell 28:387-394.
-
(1982)
Cell
, vol.28
, pp. 387-394
-
-
Sarnow, P.1
Ho, Y.S.2
Williams, J.3
Levine, A.J.4
-
119
-
-
0025639158
-
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
-
Scheffner, M., Werness, B., Huibregtse, J., Levine, A. and Howley, P. (1990) The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63:1129-1136.
-
(1990)
Cell
, vol.63
, pp. 1129-1136
-
-
Scheffner, M.1
Werness, B.2
Huibregtse, J.3
Levine, A.4
Howley, P.5
-
120
-
-
0036921603
-
Application of a yeast assay to detect functional p53 mutations in archival prostate cancer tissue
-
Shi, X.B., Di Mauro, S.M., Highshaw, R., Deitch, A.D., Evans, C.P., Gumerlock, P.H. and deVere White, R.W. (2002) Application of a yeast assay to detect functional p53 mutations in archival prostate cancer tissue. Cancer Biother Radiopharm 17:657-664.
-
(2002)
Cancer Biother Radiopharm
, vol.17
, pp. 657-664
-
-
Shi, X.B.1
Di Mauro, S.M.2
Highshaw, R.3
Deitch, A.D.4
Evans, C.P.5
Gumerlock, P.H.6
DeVere White, R.W.7
-
121
-
-
0033564131
-
The transcriptional activities of p53 and its homologue p51/p63: Similarities and differences
-
Shimada, A., Kato, S., Enjo, K., Osada, M., Ikawa, Y., Kohno, K., Obinata, M., Kanamaru, R., Ikawa, S. and Ishioka, C. (1999) The transcriptional activities of p53 and its homologue p51/p63: similarities and differences. Cancer Res 59:2781-2786.
-
(1999)
Cancer Res
, vol.59
, pp. 2781-2786
-
-
Shimada, A.1
Kato, S.2
Enjo, K.3
Osada, M.4
Ikawa, Y.5
Kohno, K.6
Obinata, M.7
Kanamaru, R.8
Ikawa, S.9
Ishioka, C.10
-
122
-
-
9144273328
-
Isolation of temperature-sensitive p53 mutations from a comprehensive missense mutation library
-
Shiraishi, K., Kato, S., Han, S.Y., Liu, W., Otsuka, K., Sakayori, M., Ishida, T., Takeda, M., Kanamaru, R., Ohuchi, N. and Ishioka, C. (2004) Isolation of temperature-sensitive p53 mutations from a comprehensive missense mutation library. J Biol Chem 279:348-355.
-
(2004)
J Biol Chem
, vol.279
, pp. 348-355
-
-
Shiraishi, K.1
Kato, S.2
Han, S.Y.3
Liu, W.4
Otsuka, K.5
Sakayori, M.6
Ishida, T.7
Takeda, M.8
Kanamaru, R.9
Ohuchi, N.10
Ishioka, C.11
-
123
-
-
1642564569
-
Regulation of p53 by Mdm2: Fate is in the numbers
-
Shmueli, A. and Oren, M. (2004) Regulation of p53 by Mdm2: fate is in the numbers. Mol Cell 13:4-5.
-
(2004)
Mol Cell
, vol.13
, pp. 4-5
-
-
Shmueli, A.1
Oren, M.2
-
124
-
-
10144259344
-
MDMX: A novel p53-binding protein with some functional properties of MDM2
-
Shvarts, A., Steegenga, W.T., Riteco, N., van Laar, T., Dekker, P., Bazuine, M., van Ham, R.C., van der Houven van Oordt, W., Hateboer, G., van der Eb, A.J. and Jochemsen, A.G. (1996) MDMX: a novel p53-binding protein with some functional properties of MDM2. EMBO J 15:5349-5357.
-
(1996)
EMBO J
, vol.15
, pp. 5349-5357
-
-
Shvarts, A.1
Steegenga, W.T.2
Riteco, N.3
Van Laar, T.4
Dekker, P.5
Bazuine, M.6
Van Ham, R.C.7
Van Der Houven Van Oordt, W.8
Hateboer, G.9
Van Der Eb, A.J.10
Jochemsen, A.G.11
-
125
-
-
0026577060
-
Mammalian p53 can function as a transcription factor in yeast
-
Scharer, E. and Iggo, R. (1992) Mammalian p53 can function as a transcription factor in yeast. Nucleic Acids Res 20:1539-1545.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 1539-1545
-
-
Scharer, E.1
Iggo, R.2
-
126
-
-
0034671945
-
Oncogenic mutations of the p53 tumor suppressor: The demons of the guardian of the genome
-
Sigal, A. and Rotter, V. (2000) Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome. Cancer Res 60:6788-6793.
-
(2000)
Cancer Res
, vol.60
, pp. 6788-6793
-
-
Sigal, A.1
Rotter, V.2
-
127
-
-
0033230581
-
The cellular response to p53: The decision between life and death
-
Sionov, R.V. and Haupt, Y. (1999) The cellular response to p53: the decision between life and death. Oncogene 18:6145-6157.
-
(1999)
Oncogene
, vol.18
, pp. 6145-6157
-
-
Sionov, R.V.1
Haupt, Y.2
-
128
-
-
16544380605
-
Analysis of tumor suppressor p53 status in head and neck squamous cell carcinoma
-
Smardova, J., Ksicova, K., Binkova, H., Krpensky, A., Pavlova, S., Rottenberg, J. and Koukalova, H. (2004) Analysis of tumor suppressor p53 status in head and neck squamous cell carcinoma. Oncol Rep 11:923-929.
-
(2004)
Oncol Rep
, vol.11
, pp. 923-929
-
-
Smardova, J.1
Ksicova, K.2
Binkova, H.3
Krpensky, A.4
Pavlova, S.5
Rottenberg, J.6
Koukalova, H.7
-
129
-
-
0033561618
-
Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions
-
Smith, P.D., Crossland, S., Parker, G., Osin, P., Brooks, L., Waller, J., Philp, E., Crompton, M.R., Gusterson, B.A., Allday, M.J. and Crook, T. (1999) Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions. Oncogene 18:2451-2459.
-
(1999)
Oncogene
, vol.18
, pp. 2451-2459
-
-
Smith, P.D.1
Crossland, S.2
Parker, G.3
Osin, P.4
Brooks, L.5
Waller, J.6
Philp, E.7
Crompton, M.R.8
Gusterson, B.A.9
Allday, M.J.10
Crook, T.11
-
130
-
-
0344668840
-
p53 stimulates human topoisomerase I activity by modulating its DNA binding
-
Soc, K. and Grosse, F. (2003) p53 stimulates human topoisomerase I activity by modulating its DNA binding. Nucleic Acids Res 31:6585-6592.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 6585-6592
-
-
Soc, K.1
Grosse, F.2
-
131
-
-
0037217669
-
Focus on the p53 gene and cancer: Advances in TP53 mutation research
-
Soussi, T. (2003) Focus on the p53 gene and cancer: advances in TP53 mutation research. Hum Mutat 21:173-175.
-
(2003)
Hum Mutat
, vol.21
, pp. 173-175
-
-
Soussi, T.1
-
132
-
-
0035751937
-
Assessing TP53 status in human tumours to evaluate clinical outcome
-
Soussi, T. and Beroud, C. (2001) Assessing TP53 status in human tumours to evaluate clinical outcome. Nat Rev Cancer 1:233-240.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 233-240
-
-
Soussi, T.1
Beroud, C.2
-
133
-
-
0035203715
-
Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms
-
Stad, R., Little, N.A., Xirodimas, D.P., Frenk, R., van der Eb, A.J., Lane, D.P., Seville, M.K. and Jochemsen, A.G. (2001) Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms. EMBO Rep 2:1029-1034.
-
(2001)
EMBO Rep
, vol.2
, pp. 1029-1034
-
-
Stad, R.1
Little, N.A.2
Xirodimas, D.P.3
Frenk, R.4
Van Der Eb, A.J.5
Lane, D.P.6
Seville, M.K.7
Jochemsen, A.G.8
-
134
-
-
0034623074
-
Hdmx stabilizes Mdm2 and p53
-
Stad, R., Ramos, Y.F., Little, N., Grivell, S., Attema, J., van Der Eb, A.J. and Jochemsen, A.G. (2000) Hdmx stabilizes Mdm2 and p53. J Biol Chem 275:28039-28044.
-
(2000)
J Biol Chem
, vol.275
, pp. 28039-28044
-
-
Stad, R.1
Ramos, Y.F.2
Little, N.3
Grivell, S.4
Attema, J.5
Van Der Eb, A.J.6
Jochemsen, A.G.7
-
135
-
-
0036920440
-
Human topoisomerase I cleavage complexes are repaired by a p53-stimulated recombination-like reaction in vitro
-
Stephan, H., Grosse, F. and Soe, K. (2002) Human topoisomerase I cleavage complexes are repaired by a p53-stimulated recombination-like reaction in vitro. Nucleic Acids Res 30:5087-5093.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 5087-5093
-
-
Stephan, H.1
Grosse, F.2
Soe, K.3
-
136
-
-
0033559256
-
A leucine-rich nuclear export signal in the p53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking
-
Stommel, J.M., Marchenko, N.D., Jimenez, G.S., Moll, U.M., Hope, T.J. and Wahl, G.M. (1999) A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. EMBO J 18:1660-1672.
-
(1999)
EMBO J
, vol.18
, pp. 1660-1672
-
-
Stommel, J.M.1
Marchenko, N.D.2
Jimenez, G.S.3
Moll, U.M.4
Hope, T.J.5
Wahl, G.M.6
-
137
-
-
0032169516
-
The alternative product from the human CDKN2A locus, p 14(ARF), participates in a regulatory feedback loop with p53 and MDM2
-
Stott, F.J., Bates, S., James, M.C., McConnell, B.B., Starborg, M., Brookes, S., Palmeto, I., Ryan, K., Hara, E., Vousden, K.H. and Peters, G. (1998) The alternative product from the human CDKN2A locus, p 14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J 17:5001-5014.
-
(1998)
EMBO J
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmeto, I.7
Ryan, K.8
Hara, E.9
Vousden, K.H.10
Peters, G.11
-
138
-
-
0025201631
-
The ADE2 gene from Saccharomyces cerevisiae: Sequence and new vectors
-
Stotz, A. and Linder, P. (1990) The ADE2 gene from Saccharomyces cerevisiae: sequence and new vectors. Gene 95:91-98.
-
(1990)
Gene
, vol.95
, pp. 91-98
-
-
Stotz, A.1
Linder, P.2
-
139
-
-
0030990910
-
Reappraisal of p53 mutations in human malignant astrocytic neoplasms by p53 functional assay: Comparison with conventional structural analyses
-
Tada, M., Iggo, R.D., Waridel, F., Nozaki, M., Matsumoto, R., Sawamura, Y., Shinohe, Y., Ikeda, J. and Abe, H. (1997) Reappraisal of p53 mutations in human malignant astrocytic neoplasms by p53 functional assay: comparison with conventional structural analyses. Mol Carcinogen 18:171-176.
-
(1997)
Mol Carcinogen
, vol.18
, pp. 171-176
-
-
Tada, M.1
Iggo, R.D.2
Waridel, F.3
Nozaki, M.4
Matsumoto, R.5
Sawamura, Y.6
Shinohe, Y.7
Ikeda, J.8
Abe, H.9
-
140
-
-
0024452546
-
p53: A frequent target for genetic abnormalities in lung cancer
-
Takahashi, T., Nau, M.M., Chiba, I., Birrer, M.J., Rosenberg, R.K., Vinocour, M., Levitt, M., Pass, H., Gazdar, A.F. and Minna, J.D. (1989) p53: a frequent target for genetic abnormalities in lung cancer. Science 246:491-494.
-
(1989)
Science
, vol.246
, pp. 491-494
-
-
Takahashi, T.1
Nau, M.M.2
Chiba, I.3
Birrer, M.J.4
Rosenberg, R.K.5
Vinocour, M.6
Levitt, M.7
Pass, H.8
Gazdar, A.F.9
Minna, J.D.10
-
141
-
-
0030860502
-
A functional assay in yeast for the human estrogen receptor displays wild-type and variant estrogen receptor messenger RNAs present in breast carcinoma
-
van Dijk, M.A., Floore, A.N., Kloppenborg, K.I. and van't Veer, L.J. (1997) A functional assay in yeast for the human estrogen receptor displays wild-type and variant estrogen receptor messenger RNAs present in breast carcinoma. Cancer Res 57:3478-3485.
-
(1997)
Cancer Res
, vol.57
, pp. 3478-3485
-
-
Van Dijk, M.A.1
Floore, A.N.2
Kloppenborg, K.I.3
Van'T Veer, L.J.4
-
142
-
-
0037222381
-
Germline TP53 mutations and Li-Fraumeni syndrome
-
Varley, J.M. (2003) Germline TP53 mutations and Li-Fraumeni syndrome. Hum Mutat 21:313-320.
-
(2003)
Hum Mutat
, vol.21
, pp. 313-320
-
-
Varley, J.M.1
-
143
-
-
7344264620
-
Genetic and functional studies of a germline TP53 splicing mutation in a Li-Fraumeni-like family
-
Varley, J.M., Chapman, P., McGown, G., Thorncroft, M., White, G.R., Greaves, M.J., Scott, D., Spreadborough, A., Tricker, K.J., Birch, J.M., Evans, D.G., Reddel, R., Camplejohn, R.S., Burn, J. and Boyle, J.M. (1998) Genetic and functional studies of a germline TP53 splicing mutation in a Li-Fraumeni-like family. Oncogene 16:3291-3298.
-
(1998)
Oncogene
, vol.16
, pp. 3291-3298
-
-
Varley, J.M.1
Chapman, P.2
McGown, G.3
Thorncroft, M.4
White, G.R.5
Greaves, M.J.6
Scott, D.7
Spreadborough, A.8
Tricker, K.J.9
Birch, J.M.10
Evans, D.G.11
Reddel, R.12
Camplejohn, R.S.13
Burn, J.14
Boyle, J.M.15
-
144
-
-
0033365202
-
Are there low-penetrance TP53 Alleles? Evidence from childhood adrenocortical tumors
-
Varley, J.M., McGown, G., Thorncroft, M., James, L.A., Margison, G.P., Forster, G., Evans, D.G., Harris, M., Kelsey, A.M. and Birch, J.M. (1999) Are there low-penetrance TP53 Alleles? Evidence from childhood adrenocortical tumors. Am J Hum Genet 65:995-1006.
-
(1999)
Am J Hum Genet
, vol.65
, pp. 995-1006
-
-
Varley, J.M.1
McGown, G.2
Thorncroft, M.3
James, L.A.4
Margison, G.P.5
Forster, G.6
Evans, D.G.7
Harris, M.8
Kelsey, A.M.9
Birch, J.M.10
-
146
-
-
0034703742
-
p53: Death star
-
Vousden, K.H. (2000) p53: death star. Cell 103:691-694.
-
(2000)
Cell
, vol.103
, pp. 691-694
-
-
Vousden, K.H.1
-
147
-
-
0037075898
-
Activation of the p53 tumor suppressor protein
-
Vousden, K.H. (2002) Activation of the p53 tumor suppressor protein. Biochim Biophys Acta 1602:47-59.
-
(2002)
Biochim Biophys Acta
, vol.1602
, pp. 47-59
-
-
Vousden, K.H.1
-
148
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden, K.H. and Lu, X. (2002) Live or let die: the cell's response to p53. Nat Rev Cancer 2:594-604.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
149
-
-
0031022938
-
Field cancerisation and polyclonal p53 mutation in the upper aero-digestive tract
-
Waridel, F., Estreicher, A., Bron, L., Flaman, J.M., Fontolliet, C., Monnier, P., Frebourg, T. and Iggo, R. (1997) Field cancerisation and polyclonal p53 mutation in the upper aero-digestive tract. Oncogene 14:163-169.
-
(1997)
Oncogene
, vol.14
, pp. 163-169
-
-
Waridel, F.1
Estreicher, A.2
Bron, L.3
Flaman, J.M.4
Fontolliet, C.5
Monnier, P.6
Frebourg, T.7
Iggo, R.8
-
150
-
-
0026951144
-
Germ-line splicing mutation of the p53 gene in a cancer-prone family
-
Warneford, S.G., Witton, L.J., Townsend, M.L., Rowe, P.B., Reddel, R.R., Dalla-Pozza, L. and Symonds, G. (1992) Germ-line splicing mutation of the p53 gene in a cancer-prone family. Cell Growth Differ 3:839-846.
-
(1992)
Cell Growth Differ
, vol.3
, pp. 839-846
-
-
Warneford, S.G.1
Witton, L.J.2
Townsend, M.L.3
Rowe, P.B.4
Reddel, R.R.5
Dalla-Pozza, L.6
Symonds, G.7
-
151
-
-
0036319338
-
Detection of SYT-SSX fusion transcripts in paraffin-embedded tissues of synovial sarcoma by reverse transcription-polymerase chain reaction
-
Wei, Y., Wang, J., Zhu, X., Shi, D., Hisaoka, M. and Hashimoto, H. (2002) Detection of SYT-SSX fusion transcripts in paraffin-embedded tissues of synovial sarcoma by reverse transcription-polymerase chain reaction. China Med J (England) 115:1043-1047.
-
(2002)
China Med J (England)
, vol.115
, pp. 1043-1047
-
-
Wei, Y.1
Wang, J.2
Zhu, X.3
Shi, D.4
Hisaoka, M.5
Hashimoto, H.6
-
152
-
-
0025271203
-
Association of human papillomavirus types 16 and 18 E6 proteins with p53
-
Werness, B.A., Levine, A.J. and Howley, P.M. (1990) Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science 248:76-79.
-
(1990)
Science
, vol.248
, pp. 76-79
-
-
Werness, B.A.1
Levine, A.J.2
Howley, P.M.3
-
153
-
-
0025832211
-
Expression of RB and p53 proteins in HPV-positive and HPV-negative cervical carcinoma cell lines
-
Wrede, D., Tidy, J.A., Crook, T., Lane, D. and Vousden, K.H. (1991) Expression of RB and p53 proteins in HPV-positive and HPV-negative cervical carcinoma cell lines. Mol Carcinogen 4:171-175.
-
(1991)
Mol Carcinogen
, vol.4
, pp. 171-175
-
-
Wrede, D.1
Tidy, J.A.2
Crook, T.3
Lane, D.4
Vousden, K.H.5
-
154
-
-
1942437663
-
Regulating the p53 system through ubiquitination
-
Yang, Y., Li, C.C.H. and Weissman, A.M. (2004) Regulating the p53 system through ubiquitination. Oncogene 23:2096-2106.
-
(2004)
Oncogene
, vol.23
, pp. 2096-2106
-
-
Yang, Y.1
Li, C.C.H.2
Weissman, A.M.3
-
155
-
-
0037264384
-
Simulated sunlight and benzo[a]pyrene diol epoxide induced mutagenesis in the human p53 gene evaluated by the yeast functional assay: Lack of correspondence to tumor mutation spectra
-
Yoon, J.H., Lee, C.S. and Pfeifer, G.P. (2003) Simulated sunlight and benzo[a]pyrene diol epoxide induced mutagenesis in the human p53 gene evaluated by the yeast functional assay: lack of correspondence to tumor mutation spectra. Carcinogenesis 24:113-119.
-
(2003)
Carcinogenesis
, vol.24
, pp. 113-119
-
-
Yoon, J.H.1
Lee, C.S.2
Pfeifer, G.P.3
-
156
-
-
0028242937
-
A temperature-sensitive mutant of human p53
-
Zhang, W., Guo, X.Y., Hu, G.Y., Liu W, B., Shay, J.W. and Deisseroth, A.B. (1994) A temperature-sensitive mutant of human p53. EMBO J 13:2535-2544.
-
(1994)
EMBO J
, vol.13
, pp. 2535-2544
-
-
Zhang, W.1
Guo, X.Y.2
Hu, G.Y.3
Liu, W.B.4
Shay, J.W.5
Deisseroth, A.B.6
-
157
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
Zhang, Y., Xiong, Y. and Yarbrough, W.G. (1998) ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 92:725-734.
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
|