-
1
-
-
0034676455
-
Surfing the p53 network
-
Vogelstein, B., Lane, D., and Levine, A. J. Surfing the p53 network. Nature, 408: 307-310, 2000.
-
(2000)
Nature
, vol.408
, pp. 307-310
-
-
Vogelstein, B.1
Lane, D.2
Levine, A.J.3
-
2
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell, 88: 323-331, 1997.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
3
-
-
0030800922
-
Mdm2: Keeping p53 under control
-
Piette, J., Neel, H., and Marechal. V. Mdm2: keeping p53 under control. Oncogene, 15. 1001-1010, 1997.
-
(1997)
Oncogene
, vol.15
, pp. 1001-1010
-
-
Piette, J.1
Neel, H.2
Marechal, V.3
-
4
-
-
0032417695
-
Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis
-
Jones, S. N., Hancock, A. R., Vogel, H., Donehower, L. A., and Bradley, A. Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis. Proc. Natl. Acad. Sci. USA, 95: 15608-15612, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15608-15612
-
-
Jones, S.N.1
Hancock, A.R.2
Vogel, H.3
Donehower, L.A.4
Bradley, A.5
-
5
-
-
0032145989
-
The MDM2 gene amplification database
-
Momand, J., Jung, D., Wilczynski, S., and Niland, J. The MDM2 gene amplification database. Nucleic Acids Res., 26: 3453-3459, 1998.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 3453-3459
-
-
Momand, J.1
Jung, D.2
Wilczynski, S.3
Niland, J.4
-
6
-
-
0027232042
-
p53 Mutation and MDM2 amplification in human soft tissue sarcomas
-
Leach, F. S., Tokino, T., Meltzer, P., Burrell, M., Oliner, J. D., Smith, S., Hill, D. E., Sidransky. D., Kinzler, K. W., and Vogelstein, B. p53 Mutation and MDM2 amplification in human soft tissue sarcomas. Cancer Res., 53: 2231-2234, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 2231-2234
-
-
Leach, F.S.1
Tokino, T.2
Meltzer, P.3
Burrell, M.4
Oliner, J.D.5
Smith, S.6
Hill, D.E.7
Sidransky, D.8
Kinzler, K.W.9
Vogelstein, B.10
-
7
-
-
0028098165
-
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
-
Cordon-Cardo, C., Latres, E., Drobnjak, M., Oliva, M. R., Pollack, D., Woodruff, J. M., Marechal, V., Chen, J., Brennan, M. F., and Levine, A. J. Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res., 54: 794-799, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 794-799
-
-
Cordon-Cardo, C.1
Latres, E.2
Drobnjak, M.3
Oliva, M.R.4
Pollack, D.5
Woodruff, J.M.6
Marechal, V.7
Chen, J.8
Brennan, M.F.9
Levine, A.J.10
-
8
-
-
0344906097
-
Prognostic relevance of C-terminal Mdm2 detection is enhanced by p53 positivity in soft tissue sarcomas
-
Wurl, P., Meye, A., Berger, D., Bache. M., Lautenschlager, C., Schmidt, H., Kalthoff, H., Rath, F. W., and Taubert, H. Prognostic relevance of C-terminal Mdm2 detection is enhanced by p53 positivity in soft tissue sarcomas. Diagn. Mol. Pathol., 6: 249-254, 1997.
-
(1997)
Diagn. Mol. Pathol.
, vol.6
, pp. 249-254
-
-
Wurl, P.1
Meye, A.2
Berger, D.3
Bache, M.4
Lautenschlager, C.5
Schmidt, H.6
Kalthoff, H.7
Rath, F.W.8
Taubert, H.9
-
9
-
-
0032485420
-
High prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremities
-
Wurl, P., Meye, A., Schmidt, H., Lautenschlager, C., Kalthoff, H., Rath, F. W., and Taubert, H. High prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremities. Oncogene, 16: 1183-1185, 1998.
-
(1998)
Oncogene
, vol.16
, pp. 1183-1185
-
-
Wurl, P.1
Meye, A.2
Schmidt, H.3
Lautenschlager, C.4
Kalthoff, H.5
Rath, F.W.6
Taubert, H.7
-
10
-
-
7144256512
-
Significance of retinoblastoma and mdm2 gene expression as prognostic markers for soft-tissue sarcoma
-
Wurl, P., Meye, A., Berger, D., Lautenschlager, C., Bache, M., Holzhausen, H. J., Schmidt, H., Dralle, H., Rath, F. W., and Taubert, H. Significance of retinoblastoma and mdm2 gene expression as prognostic markers for soft-tissue sarcoma. Langenbecks Arch. Surg., 383: 99-103, 1998.
-
(1998)
Langenbecks Arch. Surg.
, vol.383
, pp. 99-103
-
-
Wurl, P.1
Meye, A.2
Berger, D.3
Lautenschlager, C.4
Bache, M.5
Holzhausen, H.J.6
Schmidt, H.7
Dralle, H.8
Rath, F.W.9
Taubert, H.10
-
11
-
-
1042274013
-
Amplification of the MDM2 gene, but not expression of splice variants of MDM2 MRNA, is associated with prognosis in soft tissue sarcoma
-
Bartel, F., Meye, A., Wurl, P., Kappler, M., Bache, M., Lautenschlager, C., Grunbaum, U., Schmidt, H., and Taubert, H. Amplification of the MDM2 gene, but not expression of splice variants of MDM2 MRNA, is associated with prognosis in soft tissue sarcoma. Int. J. Cancer, 95: 168-175, 2001.
-
(2001)
Int. J. Cancer
, vol.95
, pp. 168-175
-
-
Bartel, F.1
Meye, A.2
Wurl, P.3
Kappler, M.4
Bache, M.5
Lautenschlager, C.6
Grunbaum, U.7
Schmidt, H.8
Taubert, H.9
-
12
-
-
0034661248
-
Analysis of the p16INK4, p14ARF, p15, TP53, and MDM2 genes and their prognostic implications in osteosarcoma and Ewing sarcoma
-
Tsuchiya, T., Sekine, K., Hinohara, S., Namiki, T., Nobori, T., and Kaneko, Y. Analysis of the p16INK4, p14ARF, p15, TP53, and MDM2 genes and their prognostic implications in osteosarcoma and Ewing sarcoma. Cancer Genet. Cytogenet., 120: 91-98, 2000.
-
(2000)
Cancer Genet. Cytogenet.
, vol.120
, pp. 91-98
-
-
Tsuchiya, T.1
Sekine, K.2
Hinohara, S.3
Namiki, T.4
Nobori, T.5
Kaneko, Y.6
-
13
-
-
0027136159
-
Infrequency of MDM2 gene amplification in pediatric solid tumors and lack of association with p53 mutations in adult squamous cell carcinomas
-
Waber, P. G., Chen, J., and Nisen, P. D. Infrequency of MDM2 gene amplification in pediatric solid tumors and lack of association with p53 mutations in adult squamous cell carcinomas. Cancer Res., 53: 6028-6030, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 6028-6030
-
-
Waber, P.G.1
Chen, J.2
Nisen, P.D.3
-
14
-
-
0033861106
-
P53 mutation and MDM2 amplification frequency in pediatric rhabdomyosarcoma tumors and cell lines
-
Taylor, A. C., Shu, L., Danks, M. K., Poquette, C. A., Shetty, S., Thayer, M. J., Houghton, P. J., and Harris, L. C. P53 mutation and MDM2 amplification frequency in pediatric rhabdomyosarcoma tumors and cell lines. Med. Pediatr. Oncol., 35: 96-103, 2000.
-
(2000)
Med. Pediatr. Oncol.
, vol.35
, pp. 96-103
-
-
Taylor, A.C.1
Shu, L.2
Danks, M.K.3
Poquette, C.A.4
Shetty, S.5
Thayer, M.J.6
Houghton, P.J.7
Harris, L.C.8
-
15
-
-
0033902014
-
Alterations of cell cycle regulators in localized synovial sarcoma: A multifactorial study with prognostic implications
-
Antonescu, C. R., Leung, D. H., Dudas, M., Ladanyi, M., Brennan, M., Woodruff, J. M., and Cordon-Cardo, C. Alterations of cell cycle regulators in localized synovial sarcoma: A multifactorial study with prognostic implications. Am. J. Pathol., 156: 977-983, 2000.
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 977-983
-
-
Antonescu, C.R.1
Leung, D.H.2
Dudas, M.3
Ladanyi, M.4
Brennan, M.5
Woodruff, J.M.6
Cordon-Cardo, C.7
-
16
-
-
0033804661
-
Molecular abnormalities of p53, MDM2, and H-ras in synovial sarcoma
-
Oda, Y., Sakamoto, A., Satio, T., Kawauchi, S., Iwamoto, Y., and Tsuneyoshi, M. Molecular abnormalities of p53, MDM2, and H-ras in synovial sarcoma. Mod. Pathol., 13: 994-1004, 2000.
-
(2000)
Mod. Pathol.
, vol.13
, pp. 994-1004
-
-
Oda, Y.1
Sakamoto, A.2
Satio, T.3
Kawauchi, S.4
Iwamoto, Y.5
Tsuneyoshi, M.6
-
17
-
-
0034488325
-
Analysis of mdm2 and p53 gene alterations in glioblastomas and its correlation with clinical factors
-
Schiebe, M., Ohneseit, P., Hoffmann, W., Meyermann, R., Rodemann, H. P., and Bamberg, M. Analysis of mdm2 and p53 gene alterations in glioblastomas and its correlation with clinical factors. J. Neurooncol., 49: 197-203, 2000.
-
(2000)
J. Neurooncol.
, vol.49
, pp. 197-203
-
-
Schiebe, M.1
Ohneseit, P.2
Hoffmann, W.3
Meyermann, R.4
Rodemann, H.P.5
Bamberg, M.6
-
18
-
-
0028868217
-
Amplification at 12q13-14 in human malignant gliomas is frequently accompanied by loss of heterozygosity at loci proximal and distal to the amplification site
-
Reifenberger, G., Reifenberger, J., Ichimura, K., and Collins, V. P. Amplification at 12q13-14 in human malignant gliomas is frequently accompanied by loss of heterozygosity at loci proximal and distal to the amplification site. Cancer Res., 55: 731-734, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 731-734
-
-
Reifenberger, G.1
Reifenberger, J.2
Ichimura, K.3
Collins, V.P.4
-
19
-
-
0027196974
-
Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations
-
Reifenberger, G., Liu, L., Ichimura, K., Schmidt, E. E., and Collins, V. P. Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. Cancer Res., 53: 2736-2739, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 2736-2739
-
-
Reifenberger, G.1
Liu, L.2
Ichimura, K.3
Schmidt, E.E.4
Collins, V.P.5
-
20
-
-
0030970202
-
MDM2 and p53 expression in gliomas: A mulivariate survival analysis including proliferation markers and epidermal growth factor receptor
-
Korkolopoulou, P., Christodoulou, P., Kouzelis, K., Hadjiyannakis, M., Priftis, A., Stamoulis, G., Seretis, A., and Thomas-Tsagli, E. MDM2 and p53 expression in gliomas: a mulivariate survival analysis including proliferation markers and epidermal growth factor receptor. Br. J. Cancer, 75: 1269-1278, 1997.
-
(1997)
Br. J. Cancer
, vol.75
, pp. 1269-1278
-
-
Korkolopoulou, P.1
Christodoulou, P.2
Kouzelis, K.3
Hadjiyannakis, M.4
Priftis, A.5
Stamoulis, G.6
Seretis, A.7
Thomas-Tsagli, E.8
-
21
-
-
0030806772
-
Prognostic factors in malignant glioma: Influence of the overexpression of oncogene and tumor-suppresor gene products on survival
-
Rainov, N. G., Dobberstein, K. U., Bahn, H., Holzhausen, H. J., Lautenschlager, C., Heidecke, V., and Burkert, W. Prognostic factors in malignant glioma: influence of the overexpression of oncogene and tumor-suppresor gene products on survival. J. Neurooncol., 35: 13-28, 1997.
-
(1997)
J. Neurooncol.
, vol.35
, pp. 13-28
-
-
Rainov, N.G.1
Dobberstein, K.U.2
Bahn, H.3
Holzhausen, H.J.4
Lautenschlager, C.5
Heidecke, V.6
Burkert, W.7
-
22
-
-
0031881733
-
Gene amplification as a prognostic factor in primary brain tumors
-
Olson, J. J., Barnett, D., Yang, J., Assietti, R., Cotsonis, G., and James, C. D. Gene amplification as a prognostic factor in primary brain tumors. Clin. Cancer Res., 4: 215-222, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 215-222
-
-
Olson, J.J.1
Barnett, D.2
Yang, J.3
Assietti, R.4
Cotsonis, G.5
James, C.D.6
-
23
-
-
0036020497
-
Immunohistochemical markers for prognosis of cerebral glioblastomas
-
Korshunov, A., Golanov, A., and Sycheva, R. Immunohistochemical markers for prognosis of cerebral glioblastomas. J. Neurooncol., 58: 217-236, 2002.
-
(2002)
J. Neurooncol.
, vol.58
, pp. 217-236
-
-
Korshunov, A.1
Golanov, A.2
Sycheva, R.3
-
24
-
-
0031671411
-
Gene amplification as a prognostic factor in primary and secondary high-grade malignant gliomas
-
Galanis, E., Buckner, J., Kimmel, D., Jenkins, R., Alderete, B., O'Fallon, J., Wang, C. H., Scheithauer, B. W., and James, C. D. Gene amplification as a prognostic factor in primary and secondary high-grade malignant gliomas. Int. J. Oncol., 13: 717-724, 1998.
-
(1998)
Int. J. Oncol.
, vol.13
, pp. 717-724
-
-
Galanis, E.1
Buckner, J.2
Kimmel, D.3
Jenkins, R.4
Alderete, B.5
O'Fallon, J.6
Wang, C.H.7
Scheithauer, B.W.8
James, C.D.9
-
25
-
-
0027368879
-
The human MDM-2 oncogene is overexpressed in leukemias
-
Bueso-Ramos, C. E., Yang, Y., de Leon, E., McCown, P., Stass, S. A., and Albitar, M. The human MDM-2 oncogene is overexpressed in leukemias. Blood, 82: 2617-2623, 1993.
-
(1993)
Blood
, vol.82
, pp. 2617-2623
-
-
Bueso-Ramos, C.E.1
Yang, Y.2
De Leon, E.3
McCown, P.4
Stass, S.A.5
Albitar, M.6
-
26
-
-
0028172753
-
Overexpression of the MDM2 gene is found in some cases of haematological malignancies
-
Quesnel, B., Preudhomme, C., Oscier, D., Lepelley, P., Collyn-d'Hooghe, M., Facon, T., Zandecki, M., and Fenaux, P. Overexpression of the MDM2 gene is found in some cases of haematological malignancies. Br J. Haematol., 88: 415-418, 1994.
-
(1994)
Br J. Haematol.
, vol.88
, pp. 415-418
-
-
Quesnel, B.1
Preudhomme, C.2
Oscier, D.3
Lepelley, P.4
Collyn-D'Hooghe, M.5
Facon, T.6
Zandecki, M.7
Fenaux, P.8
-
27
-
-
0030020462
-
High incidence of potential p53 inactivation in poor outcome childhood acute lymphoblastic leukemia at diagnosis
-
Marks, D. I., Kurz, B. W., Link, M. P., Ng, E., Shuster, J. J., Lauer, S. J., Brodsky, I., and Haines, D. S. High incidence of potential p53 inactivation in poor outcome childhood acute lymphoblastic leukemia at diagnosis. Blood, 87: 1155-1161, 1996.
-
(1996)
Blood
, vol.87
, pp. 1155-1161
-
-
Marks, D.I.1
Kurz, B.W.2
Link, M.P.3
Ng, E.4
Shuster, J.J.5
Lauer, S.J.6
Brodsky, I.7
Haines, D.S.8
-
28
-
-
0031059357
-
Altered expression of p53 and mdm-2 proteins at diagnosis is associated with early treatment failure in childhood acute lymphoblastic leukemia
-
Marks, D. I., Kurz, B. W., Link, M. P., Ng, E., Shuster, J. J., Lauer, S. J., Carroll, D., Brodsky, I., and Haines, D. S. Altered expression of p53 and mdm-2 proteins at diagnosis is associated with early treatment failure in childhood acute lymphoblastic leukemia. J. Clin. Oncol., 15: 1158-1162, 1997.
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 1158-1162
-
-
Marks, D.I.1
Kurz, B.W.2
Link, M.P.3
Ng, E.4
Shuster, J.J.5
Lauer, S.J.6
Carroll, D.7
Brodsky, I.8
Haines, D.S.9
-
29
-
-
0033959324
-
Incidence and prognostic significance of MDM2 oncoprotein overexpression in relapsed childhood acute lymphoblastic leukemia
-
Zhou, M., Gu, L., Abshire, T. C., Homans, A., Billett, A. L., Yeager, A. M., and Findley, H. W. Incidence and prognostic significance of MDM2 oncoprotein overexpression in relapsed childhood acute lymphoblastic leukemia. Leukemia, 14: 61-67, 2000.
-
(2000)
Leukemia
, vol.14
, pp. 61-67
-
-
Zhou, M.1
Gu, L.2
Abshire, T.C.3
Homans, A.4
Billett, A.L.5
Yeager, A.M.6
Findley, H.W.7
-
30
-
-
0031786826
-
Overexpression of MDM2 in acute childhood lymphoblastic leukemia
-
Gustafsson, B. and Stal, O. Overexpression of MDM2 in acute childhood lymphoblastic leukemia. Pediatr. Hematol. Oncol., 15: 519-526, 1998.
-
(1998)
Pediatr. Hematol. Oncol.
, vol.15
, pp. 519-526
-
-
Gustafsson, B.1
Stal, O.2
-
31
-
-
0035192248
-
MDM2 and p53 in childhood acute lymphoblastic leukemia: Higher expression in childhood leukemias with poor prognosis compared to long-term survivors
-
Gustafsson, B., Axelsson, B., Christensson, B., and Winiarski, J. MDM2 and p53 in childhood acute lymphoblastic leukemia: higher expression in childhood leukemias with poor prognosis compared to long-term survivors. Pediatr. Hematol. Oncol., 18: 497-508, 2001.
-
(2001)
Pediatr. Hematol. Oncol.
, vol.18
, pp. 497-508
-
-
Gustafsson, B.1
Axelsson, B.2
Christensson, B.3
Winiarski, J.4
-
32
-
-
0032710435
-
Oncoprotein MDM2 overexpression is associated with poor prognosis in distinct non-Hodgkin's lymphoma entities
-
Moller, M. B., Nielsen, O., and Pedersen, N. T. Oncoprotein MDM2 overexpression is associated with poor prognosis in distinct non-Hodgkin's lymphoma entities. Mod. Pathol., 12: 1010-1016, 1999.
-
(1999)
Mod. Pathol.
, vol.12
, pp. 1010-1016
-
-
Moller, M.B.1
Nielsen, O.2
Pedersen, N.T.3
-
33
-
-
0035022070
-
p53, Mdm2, and c-Myc overexpression is associated with a poor prognosis in aggresive non-Hodgkin's lymphomas
-
Pagnano, K. B., Vassallo, J., Lorand-Metze, I., Costa, F. F., and Saad, S. T. p53, Mdm2, and c-Myc overexpression is associated with a poor prognosis in aggresive non-Hodgkin's lymphomas. Am. J. Hematol., 67: 84-92, 2001.
-
(2001)
Am. J. Hematol.
, vol.67
, pp. 84-92
-
-
Pagnano, K.B.1
Vassallo, J.2
Lorand-Metze, I.3
Costa, F.F.4
Saad, S.T.5
-
34
-
-
17144460571
-
Frequent alteration of MDM2 and p53 in the molecular progression of recurring non-Hodgkin's lymphoma
-
Moller, M. B., Nielsen, O., and Pedersen, N. T. Frequent alteration of MDM2 and p53 in the molecular progression of recurring non-Hodgkin's lymphoma. Histopathology, 41: 322-330, 2002.
-
(2002)
Histopathology
, vol.41
, pp. 322-330
-
-
Moller, M.B.1
Nielsen, O.2
Pedersen, N.T.3
-
35
-
-
0028007535
-
Elevated levels of MDM-2 and p53 expression are associated with high grade non-Hodgkin's lymphomas
-
Finnegan, M. C., Goepel, J. R., Royds, J., Hancock, B. W., and Goyns, M. H. Elevated levels of MDM-2 and p53 expression are associated with high grade non-Hodgkin's lymphomas. Cancer Lett., 86: 215-221, 1994.
-
(1994)
Cancer Lett.
, vol.86
, pp. 215-221
-
-
Finnegan, M.C.1
Goepel, J.R.2
Royds, J.3
Hancock, B.W.4
Goyns, M.H.5
-
36
-
-
0035887146
-
HDM2 protein overexpression, but not gene amplification, is related to tumorigenesis of cutaneous melanoma
-
Polsky, D., Bastian, B. C., Hazan, C., Melzer, K., Pack, J., Houghton, A., Busam, K., Cordon-Cardo, C., and Osman, I. HDM2 protein overexpression, but not gene amplification, is related to tumorigenesis of cutaneous melanoma. Cancer Res., 61: 7642-7646, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 7642-7646
-
-
Polsky, D.1
Bastian, B.C.2
Hazan, C.3
Melzer, K.4
Pack, J.5
Houghton, A.6
Busam, K.7
Cordon-Cardo, C.8
Osman, I.9
-
37
-
-
0037021660
-
HDM2 protein overexpression and prognosis in primary malignant melanoma
-
Polsky, D., Melzer, K., Hazan, C., Panageas, K. S., Busam, K., Drobnjak, M., Kamino, H., Spira, J. G., Kopf, A. W., Houghton, A., Cordon-Cardo, C., and Osman, I. HDM2 protein overexpression and prognosis in primary malignant melanoma. J. Natl. Cancer Inst., 94: 1803-1806, 2002.
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 1803-1806
-
-
Polsky, D.1
Melzer, K.2
Hazan, C.3
Panageas, K.S.4
Busam, K.5
Drobnjak, M.6
Kamino, H.7
Spira, J.G.8
Kopf, A.W.9
Houghton, A.10
Cordon-Cardo, C.11
Osman, I.12
-
38
-
-
0030932632
-
MDM2 gene amplification and expression in non-small-cell lung cancer: Immunohistochemical expression of its protein is favourable prognostic marker in patients without p53 protein accumulation
-
Higashiyama, M., Doi, O., Kodama, K., Yokouchi, H., Kasugai, T., Ishiguro, S., Takami, K., Nakayama, T., and Nishisho, I. MDM2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is favourable prognostic marker in patients without p53 protein accumulation. Br. J. Cancer, 75: 1302-1308, 1997.
-
(1997)
Br. J. Cancer
, vol.75
, pp. 1302-1308
-
-
Higashiyama, M.1
Doi, O.2
Kodama, K.3
Yokouchi, H.4
Kasugai, T.5
Ishiguro, S.6
Takami, K.7
Nakayama, T.8
Nishisho, I.9
-
39
-
-
0033946522
-
MDM2 mRNA expression is a favorable prognostic factor in non-small-cell lung cancer
-
Ko, J. L., Cheng, Y. W., Chang, S. L., Su, J. M., Chen, C. Y., and Lee, H. MDM2 mRNA expression is a favorable prognostic factor in non-small-cell lung cancer. Int. J. Cancer, 89: 265-270, 2000.
-
(2000)
Int. J. Cancer
, vol.89
, pp. 265-270
-
-
Ko, J.L.1
Cheng, Y.W.2
Chang, S.L.3
Su, J.M.4
Chen, C.Y.5
Lee, H.6
-
40
-
-
0030053794
-
Abnormal expression of MDM-2 in breast carcinomas
-
Bueso-Ramos, C. E., Manshouri, T., Haidar, M. A., Yang, Y., McCown, P., Ordonez, N., Glassman, A., Sneige, N., and Albitar, M. Abnormal expression of MDM-2 in breast carcinomas. Breast Cancer Res. Treat., 37: 179-188, 1996.
-
(1996)
Breast Cancer Res. Treat.
, vol.37
, pp. 179-188
-
-
Bueso-Ramos, C.E.1
Manshouri, T.2
Haidar, M.A.3
Yang, Y.4
McCown, P.5
Ordonez, N.6
Glassman, A.7
Sneige, N.8
Albitar, M.9
-
41
-
-
0035300512
-
Alternative and aberrant messenger RNA splicing of the mdm2 oncogene in invasive breast cancer
-
Lukas, J., Gao, D. Q., Keshmeshian, M., Wen, W. H., Tsao-Wei, D., Rosenberg, S., and Press, M. F. Alternative and aberrant messenger RNA splicing of the mdm2 oncogene in invasive breast cancer. Cancer Res., 61: 3212-3219, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 3212-3219
-
-
Lukas, J.1
Gao, D.Q.2
Keshmeshian, M.3
Wen, W.H.4
Tsao-Wei, D.5
Rosenberg, S.6
Press, M.F.7
-
42
-
-
0036159438
-
Overexpression of MDM2 oncoprotein correlates with possession of estrogen receptor alpha and lack of MDM2 mRNA splice variants in human breast cancer
-
Hori, M., Shimazaki, J., Inagawa, S., and Itabashi, M. Overexpression of MDM2 oncoprotein correlates with possession of estrogen receptor alpha and lack of MDM2 mRNA splice variants in human breast cancer. Breast Cancer Res. Treat., 71: 77-83, 2002.
-
(2002)
Breast Cancer Res. Treat.
, vol.71
, pp. 77-83
-
-
Hori, M.1
Shimazaki, J.2
Inagawa, S.3
Itabashi, M.4
-
43
-
-
0037505736
-
p53-independent activation of the hDM2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells
-
Phelps, M., Darley, M., Primrose, J. N., and Blaydes, J. P. p53-independent activation of the hDM2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells. Cancer Res., 63: 2616-2623, 2003.
-
(2003)
Cancer Res.
, vol.63
, pp. 2616-2623
-
-
Phelps, M.1
Darley, M.2
Primrose, J.N.3
Blaydes, J.P.4
-
44
-
-
0037130473
-
p53 induces the expression of its antagonist p73 Δ N, establishing an autoregulatory feedback loop
-
Kartasheva, N. N., Contente, A., Lenz-Stoppler, C., Roth, J., and Dobbelstein, M. p53 induces the expression of its antagonist p73 Δ N, establishing an autoregulatory feedback loop. Oncogene, 21: 4715-4727, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 4715-4727
-
-
Kartasheva, N.N.1
Contente, A.2
Lenz-Stoppler, C.3
Roth, J.4
Dobbelstein, M.5
-
45
-
-
0036203514
-
Autoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoter
-
Nakagawa, T., Takahashi, M., Ozaki, T., Watanabe Ki, K., Todo, S., Mizuguchi, H., Hayakawa, T., and Nakagawara, A. Autoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoter. Mol. Cell. Biol., 22: 2575-2585, 2002.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2575-2585
-
-
Nakagawa, T.1
Takahashi, M.2
Ozaki, T.3
Watanabe Ki, K.4
Todo, S.5
Mizuguchi, H.6
Hayakawa, T.7
Nakagawara, A.8
-
46
-
-
0034628491
-
p73 transcriptional activity increases upon cooperation between its spliced forms
-
Alarcon-Vargas, D., Fuchs, S. Y., Deb, S., and Ronai, Z. p73 transcriptional activity increases upon cooperation between its spliced forms. Oncogene, 19, 831-835, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 831-835
-
-
Alarcon-Vargas, D.1
Fuchs, S.Y.2
Deb, S.3
Ronai, Z.4
-
47
-
-
0036892018
-
Complex transcriptional effects of p63 isoforms: Identification of novel activation and repression domains
-
Ghioni, P., Bolognese, F., Duijf, P. H., Van Bokhoven, H., Mantovani, R., and Guerrini, L. Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains. Mol. Cell. Biol., 22: 8659-8668, 2002.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 8659-8668
-
-
Ghioni, P.1
Bolognese, F.2
Duijf, P.H.3
Van Bokhoven, H.4
Mantovani, R.5
Guerrini, L.6
-
48
-
-
0034743628
-
p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes
-
Dohn, M., Zhang, S., and Chen, X. p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes. Oncogene, 20: 3193-3205, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 3193-3205
-
-
Dohn, M.1
Zhang, S.2
Chen, X.3
-
49
-
-
0037169519
-
The human MDM2 oncoprotein increases the transcriptional activity and the protein level of the p53 homolog p63
-
Calabro, V., Mansueto, G., Parisi, T., Vivo, M., Calogero, R. A., and La Mantia, G. The human MDM2 oncoprotein increases the transcriptional activity and the protein level of the p53 homolog p63. J. Biol. Chem., 277: 2674-2681, 2002.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2674-2681
-
-
Calabro, V.1
Mansueto, G.2
Parisi, T.3
Vivo, M.4
Calogero, R.A.5
La Mantia, G.6
-
50
-
-
0035958574
-
Hdmx and Mdm2 can repress transcription activation by p53 but not by p63
-
Little, N. A. and Jochemsen, A. G. Hdmx and Mdm2 can repress transcription activation by p53 but not by p63. Oncogene, 20: 4576-4580, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 4576-4580
-
-
Little, N.A.1
Jochemsen, A.G.2
-
51
-
-
0035866337
-
A possible role of p73 on the modulation of p53 level through MDM2
-
Wang, X. Q., Ongkeko, W. M., Lau, A. W., Leung, K. M., and Poon, R. Y. A possible role of p73 on the modulation of p53 level through MDM2. Cancer Res., 61: 1598-1603, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 1598-1603
-
-
Wang, X.Q.1
Ongkeko, W.M.2
Lau, A.W.3
Leung, K.M.4
Poon, R.Y.5
-
52
-
-
0034234312
-
Frequent alteration of p63 expression in human primary bladder carcinomas
-
Park, B. J., Lee, S. J., Kim, J. I., Lee, C. H., Chang, S. G., Park, J. H., and Chi, S. G. Frequent alteration of p63 expression in human primary bladder carcinomas. Cancer Res., 60: 3370-3374, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 3370-3374
-
-
Park, B.J.1
Lee, S.J.2
Kim, J.I.3
Lee, C.H.4
Chang, S.G.5
Park, J.H.6
Chi, S.G.7
-
53
-
-
0034644195
-
High level expression of deltaN-p63: A mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)?
-
Crook, T., Nicholls, J. M., Brooks, L., O'Nions, J., and Allday, M. J. High level expression of deltaN-p63: a mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)? Oncogene, 19: 3439-3444, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 3439-3444
-
-
Crook, T.1
Nicholls, J.M.2
Brooks, L.3
O'Nions, J.4
Allday, M.J.5
-
54
-
-
0035859001
-
Functional characterization of naturally occurring mutants (P405R and P425L) of p73alpha and p73beta found in neuroblastoma and lung cancer
-
Naka, M., Ozaki, T., Takada, N., Takahashi, M., Shishikura, T., Sakiyama, S., Tada, M., Todo, S., and Nakagawara, A. Functional characterization of naturally occurring mutants (P405R and P425L) of p73alpha and p73beta found in neuroblastoma and lung cancer. Oncogene, 20: 3568-3572, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 3568-3572
-
-
Naka, M.1
Ozaki, T.2
Takada, N.3
Takahashi, M.4
Shishikura, T.5
Sakiyama, S.6
Tada, M.7
Todo, S.8
Nakagawara, A.9
-
55
-
-
0035653493
-
Expression of oncogenes, tumour suppressor, mismatch repair and apoptosis-related genes in primary and metastatic melanoma cells
-
Zhang, H. and Rosdahl, I. Expression of oncogenes, tumour suppressor, mismatch repair and apoptosis-related genes in primary and metastatic melanoma cells. Int. J. Oncol., 19: 1149-1153, 2001.
-
(2001)
Int. J. Oncol.
, vol.19
, pp. 1149-1153
-
-
Zhang, H.1
Rosdahl, I.2
-
56
-
-
0036714949
-
The expression of p73, p21 and MDM2 proteins in gliomas
-
Kamiya, M. and Nakazato, Y. The expression of p73, p21 and MDM2 proteins in gliomas. J. Neurooncol., 59: 143-149, 2002.
-
(2002)
J. Neurooncol.
, vol.59
, pp. 143-149
-
-
Kamiya, M.1
Nakazato, Y.2
-
57
-
-
0034863683
-
Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53
-
Parant, J., Chavez-Reyes, A., Little, N. A., Yan, W., Reinke, V., Jochemsen, A. G., and Lozano, G. Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53. Nat. Genet., 29: 92-95, 2001.
-
(2001)
Nat. Genet.
, vol.29
, pp. 92-95
-
-
Parant, J.1
Chavez-Reyes, A.2
Little, N.A.3
Yan, W.4
Reinke, V.5
Jochemsen, A.G.6
Lozano, G.7
-
58
-
-
0343819885
-
Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification
-
Riemenschneider, M. J., Buschges, R., Wolter, M., Reifenberger, J., Bostrom, J., Kraus, J. A., Schlegel, U., and Reifenberger, G. Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification. Cancer Res., 59: 6091-6096, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 6091-6096
-
-
Riemenschneider, M.J.1
Buschges, R.2
Wolter, M.3
Reifenberger, J.4
Bostrom, J.5
Kraus, J.A.6
Schlegel, U.7
Reifenberger, G.8
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