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Volumn 16, Issue 3, 1996, Pages 1126-1137

Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

EID: 0030048389     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.3.1126     Document Type: Article
Times cited : (258)

References (71)
  • 1
    • 0028899276 scopus 로고
    • Multiple patterns of MDM-2 deregulation in human leukemias: Implications in leukemogenesis and prognosis
    • Bueso-Ramos, C. E., T. Manshouri, M. A. Haidar, Y. O. Huh, M. J. Keating, and M. Albitar. 1995. Multiple patterns of MDM-2 deregulation in human leukemias: implications in leukemogenesis and prognosis. Leukemia Lymphomas 17:13-18.
    • (1995) Leukemia Lymphomas , vol.17 , pp. 13-18
    • Bueso-Ramos, C.E.1    Manshouri, T.2    Haidar, M.A.3    Huh, Y.O.4    Keating, M.J.5    Albitar, M.6
  • 2
    • 0023906055 scopus 로고
    • Isolation and sequencing of a cDNA clone encoding lysosomal membrane glycoprotcm mLAMP-1; sequence similarity to proteins bearing onco-differentiation antigens
    • Chen, J. W., Y. Cha, K. U. Yuksel, R. W. Gracy, and J. T. August 1988. Isolation and sequencing of a cDNA clone encoding lysosomal membrane glycoprotcm mLAMP-1; sequence similarity to proteins bearing onco-differentiation antigens. J Biol. Chem. 263:8754-8758.
    • (1988) J Biol. Chem. , vol.263 , pp. 8754-8758
    • Chen, J.W.1    Cha, Y.2    Yuksel, K.U.3    Gracy, R.W.4    August, J.T.5
  • 4
    • 0026529909 scopus 로고
    • Immune response to p53 is dependent upon p53/HSP 70 completes in breast cancers
    • Davidoff, A. M., J. D. Iglehart, and J. R. Marks. 1992. Immune response to p53 is dependent upon p53/HSP 70 completes in breast cancers. Proc. Natl. Acad. Sci. USA 89:3439-3442.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 3439-3442
    • Davidoff, A.M.1    Iglehart, J.D.2    Marks, J.R.3
  • 5
    • 0026530821 scopus 로고
    • Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines
    • Davidoff, A. M., J. C. Pence, N. A. Shorter, J. D. Iglehart, and J. R. Marks. 1992 Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines. Oncogene 7:127-133.
    • (1992) Oncogene , vol.7 , pp. 127-133
    • Davidoff, A.M.1    Pence, J.C.2    Shorter, N.A.3    Iglehart, J.D.4    Marks, J.R.5
  • 6
    • 0027251720 scopus 로고
    • Wild-type p53 mediates apoptosis by E1A which is inhibited by E1B
    • Debbas, M., and E. White. 1993. Wild-type p53 mediates apoptosis by E1A which is inhibited by E1B. Genes Dev 7:546-554
    • (1993) Genes Dev , vol.7 , pp. 546-554
    • Debbas, M.1    White, E.2
  • 7
    • 0028325483 scopus 로고
    • Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7
    • Demers, W., S. A. Foster, C. L. Halbert, and D. A. Galloway. 1994. Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7. Proc. Natl. Acad. Sci. USA 91:4382-4386.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4382-4386
    • Demers, W.1    Foster, S.A.2    Halbert, C.L.3    Galloway, D.A.4
  • 8
    • 0026661440 scopus 로고
    • Host cell reactivation of gamma-irradiated adenovirus 5 in human cell lines of varying radiosensitivity
    • Eady, J. J., and J. H. Peacock. 1992. Host cell reactivation of gamma-irradiated adenovirus 5 in human cell lines of varying radiosensitivity. Br. J. Cancer 66:113-118.
    • (1992) Br. J. Cancer , vol.66 , pp. 113-118
    • Eady, J.J.1    Peacock, J.H.2
  • 11
    • 0027157304 scopus 로고
    • Hepatitis B X antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma
    • Feitelson, M. A., M. Zhun, L. X. Duan, and W. T. London. 1993. Hepatitis B X antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma. Oncogene 8:1109-1117.
    • (1993) Oncogene , vol.8 , pp. 1109-1117
    • Feitelson, M.A.1    Zhun, M.2    Duan, L.X.3    London, W.T.4
  • 13
    • 0026650531 scopus 로고
    • A transcriptionally active DNA binding site for human p53 protein complexes
    • Funk, W. D., D. T. Pak, R. H. Karas, W. E. Wright, and J. W. Shay. 1992. A transcriptionally active DNA binding site for human p53 protein complexes. Mol. Cell. Biol. 12:2866-2871.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2866-2871
    • Funk, W.D.1    Pak, D.T.2    Karas, R.H.3    Wright, W.E.4    Shay, J.W.5
  • 14
    • 0025975701 scopus 로고
    • Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport
    • Gannon, J. V., and D. P. Lane. 1991. Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport Nature (London) 349:802-806.
    • (1991) Nature (London) , vol.349 , pp. 802-806
    • Gannon, J.V.1    Lane, D.P.2
  • 15
    • 0025964061 scopus 로고
    • Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein
    • Ginsberg, D., D. Michael-Michalovitz, D. Ginsberg, and M. Oren. 1991. Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein. Mol. Cell. Biol. 11:582-585.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 582-585
    • Ginsberg, D.1    Michael-Michalovitz, D.2    Ginsberg, D.3    Oren, M.4
  • 16
    • 0019853256 scopus 로고
    • Passage of viral membrane proteins through the Golgi complex
    • Green, J., G. Griffith, D. Louvard, P. Quinn, and G. Warren. 1981. Passage of viral membrane proteins through the Golgi complex. J. Mol. Biol. 152: 663-698
    • (1981) J. Mol. Biol. , vol.152 , pp. 663-698
    • Green, J.1    Griffith, G.2    Louvard, D.3    Quinn, P.4    Warren, G.5
  • 18
    • 0022969084 scopus 로고
    • Radiation therapy in the management of neuroblastoma: The Duke University Medical Center experience from 1967-1984
    • Halperin, E. C., and E. B. Cox. 1986. Radiation therapy in the management of neuroblastoma: the Duke University Medical Center experience from 1967-1984. Int J. Radiat. Oncol. Biol. Phys. 12:1829-1837.
    • (1986) Int J. Radiat. Oncol. Biol. Phys. , vol.12 , pp. 1829-1837
    • Halperin, E.C.1    Cox, E.B.2
  • 19
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip 1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper, J. W., G. R. Adam, N. Wei, K. Keyomars, and S. J. Elledge. 1993. The p21 Cdk-interacting protein Cip 1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adam, G.R.2    Wei, N.3    Keyomars, K.4    Elledge, S.J.5
  • 20
    • 0027489384 scopus 로고
    • Clinical implication of the p53 tumor suppressor gene
    • Harris, C. C., and M. Hollstein. 1993. Clinical implication of the p53 tumor suppressor gene. N. Engl. J. Med. 329:1318-1327.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 1318-1327
    • Harris, C.C.1    Hollstein, M.2
  • 21
    • 0023394825 scopus 로고
    • Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines
    • Hinds, P. W., C. A. Finlay, A. B. Frey, and A. J. Levine. 1987. Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines. Mol. Cell. Biol. 7:2863-2869.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2863-2869
    • Hinds, P.W.1    Finlay, C.A.2    Frey, A.B.3    Levine, A.J.4
  • 23
    • 0020076348 scopus 로고
    • Ultraviolet radiation sensitivity of proliferating and differentiated human neuroblastoma cells
    • James, M., and J. Mansbridge. 1982. Ultraviolet radiation sensitivity of proliferating and differentiated human neuroblastoma cells. Int. J. Radiat. Biol. 41:547-556.
    • (1982) Int. J. Radiat. Biol. , vol.41 , pp. 547-556
    • James, M.1    Mansbridge, J.2
  • 24
    • 0027501841 scopus 로고
    • Wild type p53 can mediate sequence-specific transactivation of an internal promoter within the mdm2 gene
    • Juven, T., Y. Barak, A. Zauberman, D. L. George, and M. Oren. 1993. Wild type p53 can mediate sequence-specific transactivation of an internal promoter within the mdm2 gene. Oncogene 8:3411-3416.
    • (1993) Oncogene , vol.8 , pp. 3411-3416
    • Juven, T.1    Barak, Y.2    Zauberman, A.3    George, D.L.4    Oren, M.5
  • 27
    • 0016808903 scopus 로고
    • The management of abdominal neuroblastomas
    • Koop, C. E., and L. Schnaufer. 1975. The management of abdominal neuroblastomas Cancer 35:905-909.
    • (1975) Cancer , vol.35 , pp. 905-909
    • Koop, C.E.1    Schnaufer, L.2
  • 29
    • 0028210429 scopus 로고
    • Endogenous p53 protein generated from wild type alternatively spliced p53 RNA in mouse epidermal cells
    • Kulesz-Martin, M. F., B. Lisafeld, H. Huang, N. D. Kisiel, and L. Lee. 1994. Endogenous p53 protein generated from wild type alternatively spliced p53 RNA in mouse epidermal cells. Mol. Cell, Biol. 14:1698-1708.
    • (1994) Mol. Cell, Biol. , vol.14 , pp. 1698-1708
    • Kulesz-Martin, M.F.1    Lisafeld, B.2    Huang, H.3    Kisiel, N.D.4    Lee, L.5
  • 30
    • 0027109075 scopus 로고
    • p53, the guardian of the genome
    • Lane, D. P. 1992 p53, the guardian of the genome. Nature (London) 358: 15-16.
    • (1992) Nature (London) , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 31
    • 0025173845 scopus 로고
    • P53: Oncogene or anti-oncogene?
    • Lane, D. P., and S. Benchimol. 1990. P53: oncogene or anti-oncogene? Genes Dev 4:1-8.
    • (1990) Genes Dev , vol.4 , pp. 1-8
    • Lane, D.P.1    Benchimol, S.2
  • 33
    • 0028236179 scopus 로고
    • N-myc gene copy number in neuroblastoma cell lines and resistance to experimental treatment
    • Livingstone, A., R. J. Mairs, J. Russell, J. O'Donoghue, M. N. Gaze, and T. E. Wheldon. 1994. N-myc gene copy number in neuroblastoma cell lines and resistance to experimental treatment. Eur. J. Cancer 30A:382-389.
    • (1994) Eur. J. Cancer , vol.30 A , pp. 382-389
    • Livingstone, A.1    Mairs, R.J.2    Russell, J.3    O'Donoghue, J.4    Gaze, M.N.5    Wheldon, T.E.6
  • 34
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone, L. R., A. White, J. Sprouse, E. Livanos, T. Jacks, and T. D. Tlsty. 1992. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70:923-935.
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, L.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tlsty, T.D.6
  • 35
    • 0027332996 scopus 로고
    • Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosome instability syndromes?
    • Lu, X., and D. P. Lane. 1993. Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes? Cell 75:765-778.
    • (1993) Cell , vol.75 , pp. 765-778
    • Lu, X.1    Lane, D.P.2
  • 36
    • 0026093164 scopus 로고
    • Cellular localization and cell cycle regulation by a temperature sensitive p53 protein
    • Martinez, J., I. Georgoff, J. Martinez, and A. J. Levine. 1991. Cellular localization and cell cycle regulation by a temperature sensitive p53 protein. Genes Dev. 5:151-159
    • (1991) Genes Dev. , vol.5 , pp. 151-159
    • Martinez, J.1    Georgoff, I.2    Martinez, J.3    Levine, A.J.4
  • 37
    • 0025164599 scopus 로고
    • The relationship of DNA double strand break induction to radiosensitivity in human tumor cell lines
    • McMillan, T. J., A. M. Cassoni, S. Edwards, A. Holmes, and J. H. Peacock. 1990. The relationship of DNA double strand break induction to radiosensitivity in human tumor cell lines. Int. J. Radiat. Biol. 58:427-438.
    • (1990) Int. J. Radiat. Biol. , vol.58 , pp. 427-438
    • McMillan, T.J.1    Cassoni, A.M.2    Edwards, S.3    Holmes, A.4    Peacock, J.H.5
  • 40
    • 0027079358 scopus 로고
    • The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein
    • Mietz, J. A., T. Unger, J. M. Huibregtse, and P. M. Howley. 1992. The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J. 11:5013-5020.
    • (1992) EMBO J. , vol.11 , pp. 5013-5020
    • Mietz, J.A.1    Unger, T.2    Huibregtse, J.M.3    Howley, P.M.4
  • 41
    • 85035157939 scopus 로고    scopus 로고
    • Unpublished data
    • Moll, U. M. Unpublished data.
    • Moll, U.M.1
  • 42
    • 85035158290 scopus 로고    scopus 로고
    • Unpublished data
    • Moll, U. M., et al. Unpublished data.
    • Moll, U.M.1
  • 43
    • 0029049828 scopus 로고
    • Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors
    • Moll, U. M., M. LaQuaglia, J. Benard, and G. Riou. 1995. Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc. Natl. Acad. Sci. USA 92: 4407-4411.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4407-4411
    • Moll, U.M.1    LaQuaglia, M.2    Benard, J.3    Riou, G.4
  • 44
    • 0026694826 scopus 로고
    • Two distinct mechanisms alter p53 in breast cancer: Mutation and nuclear exclusion
    • Moll, U. M., G. Riou, and A. J. Levine. 1992. Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc. Natl. Acad. Sci. USA 89:7262-7266.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7262-7266
    • Moll, U.M.1    Riou, G.2    Levine, A.J.3
  • 45
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand, J., G. P. Zambetti, D. C. Olson, D. George, and A. J. Levine. 1992. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69:1237-1245
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 47
    • 0028204160 scopus 로고
    • DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways
    • Nelson, W. G., and M. B. Kastan. 1994. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell. Biol. 14:1815-1823.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1815-1823
    • Nelson, W.G.1    Kastan, M.B.2
  • 48
    • 0028342664 scopus 로고
    • Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
    • Noda, A., Y. Ning, S. F. Venable, O. M. Pereira-Smith, and J. R. Smith. 1994. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen Exp. Cell Res. 211:90-98.
    • (1994) Exp. Cell Res. , vol.211 , pp. 90-98
    • Noda, A.1    Ning, Y.2    Venable, S.F.3    Pereira-Smith, O.M.4    Smith, J.R.5
  • 50
    • 0019830333 scopus 로고
    • Posttranslational regulation of the 54K cellular tumor antigen in normal and transformed cells
    • Oren, M., W. Maltzman, and A. J. Levine. 1981. Posttranslational regulation of the 54K cellular tumor antigen in normal and transformed cells. Mol. Cell. Biol. 1:101-110.
    • (1981) Mol. Cell. Biol. , vol.1 , pp. 101-110
    • Oren, M.1    Maltzman, W.2    Levine, A.J.3
  • 52
    • 0023818797 scopus 로고
    • Modulation of Mr 53,000 protein with induction of differentiation of human neuroblastoma cells
    • Sidell, N., and H. P. Koeffler. 1988 Modulation of Mr 53,000 protein with induction of differentiation of human neuroblastoma cells. Cancer Res. 48: 2226-2230
    • (1988) Cancer Res. , vol.48 , pp. 2226-2230
    • Sidell, N.1    Koeffler, H.P.2
  • 53
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner, M., B. A. Werness, M. Huibregtse, A. J. Levine, and P. M. Howley. 1990. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63:1129-1136
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, M.3    Levine, A.J.4    Howley, P.M.5
  • 54
    • 0025203803 scopus 로고
    • Subcellular distributions of the p53 protein during the cell cycle of Balb/C 3T3 cells
    • Shaulsky, G., A. Ben-Ze'ev, and V. Rotter. 1990. Subcellular distributions of the p53 protein during the cell cycle of Balb/C 3T3 cells. Oncogene 5: 1707-1711.
    • (1990) Oncogene , vol.5 , pp. 1707-1711
    • Shaulsky, G.1    Ben-Ze'ev, A.2    Rotter, V.3
  • 55
    • 0025201181 scopus 로고
    • Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumongenesis
    • Shaulsky, G., N. Goldfinger, A. Ben-Ze'ev, and V. Rotter. 1990. Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumongenesis. Mol. Cell. Biol. 10:6565-6577.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6565-6577
    • Shaulsky, G.1    Goldfinger, N.2    Ben-Ze'ev, A.3    Rotter, V.4
  • 56
    • 0026309246 scopus 로고
    • Involvement of wild-type p53 protein in the cell cycle requires nuclear localization
    • Shaulsky, G., N. Goldfinger, A. Peled, and V. Rotter. 1991. Involvement of wild-type p53 protein in the cell cycle requires nuclear localization. Cell Growth Differ. 2:661-667
    • (1991) Cell Growth Differ. , vol.2 , pp. 661-667
    • Shaulsky, G.1    Goldfinger, N.2    Peled, A.3    Rotter, V.4
  • 57
    • 0026046039 scopus 로고
    • Nuclear localization is essential for the activity of p53 protein
    • Shaulsky, G., N. Goldfinger, M. Tosky, A. J. Levine, and V. Rotter. 1991. Nuclear localization is essential for the activity of p53 protein. Oncogene 6: 2055-2065.
    • (1991) Oncogene , vol.6 , pp. 2055-2065
    • Shaulsky, G.1    Goldfinger, N.2    Tosky, M.3    Levine, A.J.4    Rotter, V.5
  • 58
    • 0028033418 scopus 로고
    • Potential role of human cytomegalovirus and p53 interaction in coronary restenosis
    • Speir, E., R. Modaki, E. S. Huang, M. B. Leon, F. Shawl, T. Kinkel, and S. E. Epstein. 1994. Potential role of human cytomegalovirus and p53 interaction in coronary restenosis. Science 265:391-394.
    • (1994) Science , vol.265 , pp. 391-394
    • Speir, E.1    Modaki, R.2    Huang, E.S.3    Leon, M.B.4    Shawl, F.5    Kinkel, T.6    Epstein, S.E.7
  • 59
    • 0027225785 scopus 로고
    • Protein synthesis-dependent cytoplasmic translocation of p53 protein after serum stimulation of growth-arrested MCF-7 cells
    • Takahashi, K., H. Sumimoto, K. Suzuki, and T. Ono. 1993. Protein synthesis-dependent cytoplasmic translocation of p53 protein after serum stimulation of growth-arrested MCF-7 cells. Mol. Carcinog. 8:58-66.
    • (1993) Mol. Carcinog. , vol.8 , pp. 58-66
    • Takahashi, K.1    Sumimoto, H.2    Suzuki, K.3    Ono, T.4
  • 62
    • 0027946910 scopus 로고
    • Molecular chaperones cooperate with PIM 1 protease in the degradation of misfolded proteins in mitochondria
    • Wagner, I., H. Arlt, L. van Djck, T. Langer, and W. Neupert. 1994. Molecular chaperones cooperate with PIM 1 protease in the degradation of misfolded proteins in mitochondria. EMBO J. 13:5135-5145.
    • (1994) EMBO J. , vol.13 , pp. 5135-5145
    • Wagner, I.1    Arlt, H.2    Van Djck, L.3    Langer, T.4    Neupert, W.5
  • 63
    • 0001655748 scopus 로고
    • Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity and association with transcription factor ERCC 3
    • Wang, X. W., K. Forrester, H. Yeh, M. A. Feitelson, J.-R. Gu, and C. C. Harris. 1994 Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity and association with transcription factor ERCC 3. Proc. Natl. Acad. Sci. USA 91:2230-2234.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2230-2234
    • Wang, X.W.1    Forrester, K.2    Yeh, H.3    Feitelson, M.A.4    Gu, J.-R.5    Harris, C.C.6
  • 64
    • 0028087776 scopus 로고
    • P53, guardian of Rb
    • White, E. 1994 P53, guardian of Rb. Nature (London) 371:21-22
    • (1994) Nature (London) , vol.371 , pp. 21-22
    • White, E.1
  • 65
    • 0020530724 scopus 로고
    • A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis
    • Vindelov, L. L., I. J. Christensen, and N. I. Nissen. 1983. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 3:323-327.
    • (1983) Cytometry , vol.3 , pp. 323-327
    • Vindelov, L.L.1    Christensen, I.J.2    Nissen, N.I.3
  • 66
    • 0027246716 scopus 로고
    • Regulation of p53 protein expression in human breast cancer cell lines
    • Vojtesek, B., and D. P. Lane. 1993. Regulation of p53 protein expression in human breast cancer cell lines. J. Life Sci. 105:607-612.
    • (1993) J. Life Sci. , vol.105 , pp. 607-612
    • Vojtesek, B.1    Lane, D.P.2
  • 67
    • 0027244853 scopus 로고
    • The p53-mem2 autoregulatory feedback loop
    • Wu, X., J. H. Bayle, D. Olson, and A. J. Levine. 1993. The p53-mem2 autoregulatory feedback loop. Genes Dev. 7:1126-1132.
    • (1993) Genes Dev. , vol.7 , pp. 1126-1132
    • Wu, X.1    Bayle, J.H.2    Olson, D.3    Levine, A.J.4
  • 69
    • 0026560315 scopus 로고
    • Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein
    • Yew, P. R., and A. J. Berk. 1992. Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein. Nature (London) 357: 82-85.
    • (1992) Nature (London) , vol.357 , pp. 82-85
    • Yew, P.R.1    Berk, A.J.2
  • 70
    • 0022472735 scopus 로고
    • Monoclonal antibody analysis of p53 expression in normal and transformed cells
    • Yewdell, J. W., J. V. Gannon, and D. P. Lane. 1986. Monoclonal antibody analysis of p53 expression in normal and transformed cells. J. Virol. 59: 444-452.
    • (1986) J. Virol. , vol.59 , pp. 444-452
    • Yewdell, J.W.1    Gannon, J.V.2    Lane, D.P.3
  • 71
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • Yin, Y., M. A. Tainsky, F. Z. Bischoff, L. Z. Strong, and G. M. Wahl. 1992. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles Cell 70:937-948
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin, Y.1    Tainsky, M.A.2    Bischoff, F.Z.3    Strong, L.Z.4    Wahl, G.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.