Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions

Oncogene

Volumn 18, Issue 15, 1999, Pages 2451-2459

  Smith, Paul D ^a   Crossland, Susan ^a   Parker, Gillian ^b   Osin, Peter ^a   Brooks, Louise ^c   Waller, Joanne ^a   Philp, Elizabeth ^a   Crompton, Mark R ^a   Gusterson, Barry A ^a   Allday, Martin J ^b   Crook, Tim ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

BRCA 1; BRCA 2; Breast; Mutation; Novel; p53

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; MUTANT PROTEIN; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST CANCER; CONTROLLED STUDY; EMBRYO; FEMALE; FIBROBLAST; GERM LINE; GROWTH INHIBITION; HUMAN; HUMAN TISSUE; INHERITANCE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; RAT; TRANSACTIVATION; TUMOR;

ANIMALS; APOPTOSIS; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; CARCINOMA; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; EMBRYO; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC COMPLEMENTATION TEST; HUMANS; MUTATION; NEOPLASM PROTEINS; RATS; SUPPRESSION, GENETIC; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0033561618     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202565     Document Type: Article

References (39)

1. Brugarolas J and Jacks T. (1997). Nature Med., 3, 721-722.
2. Caelles C, Helmberg A and Karin M. (1994). Nature, 370, 220-223.
3. Collins N, McManus R, Wooster R, Mangion J, Seal S, Lakhani SR, Ormiston W, Daly PA, Ford D, Easton D and Stratton MR. (1995). Oncogene, 10, 1673-1675.
4. Connor F, Bertwistle D, Mee PJ, Ross GM, Swift S, Grigorieva E, Tybulewicz VL, Ashworth A. (1997). Nature Genetics, 17, 423-430.
5. Crook T, Fisher C and Vousden KH. (1991). J. Virol., 65, 505-510.
6. Crook T, Marston N, Sara E and Vousden KH. (1994). Cell, 79, 817-827.
7. Crook T, Crossland S, Crompton MR, Osin P and Gusterson BA. (1997). Lancet, 350, 638-639.
8. Crook T, Parker GA, Rozycka M, Crossland S and Allday MJ. (1998a). Oncogene, 16, 1429-1441.
9. Crook TR, Brooks LA, Crossland S, Osin P, Barker KT, Waller J, Philp E, Smith PD, Yulug I, Peto J, Parker G, Allday MJ, Crompton MR and Gusterson BA. (1998b). Oncogene, 17, 1681-1689.
10. El-Deiry WS, Harper JW, O'Connor PM, Velculescu VE, Canman CE, Jackman J, Pientenpol JA, Burrell M, Hill DE, Wang Y, Wilman KG, Mercer WE, Kastan MB, Kohn KW, Elledge SJ, Kinzler KW and Vogelstein B. (1994). Cancer Res., 54, 1169-1174.
11. Fredersdorf S, Milne AW, Hall PA and Lu X. (1996). Am. J. Path., 148, 825-835.
12. Hakem R, de la Pompa JL, Sirard C, Mo R, Woo M, Hakem A et al. (1996). Cell, 11, 1009-1023.
13. Hakem R, de la Pompa JL, Elia A, Potter J and Mak TW. (1997). Nature Genetics, 16, 298-301.
14. Haupt Y, Rowan S, Shaulian E, Vousden KH and Oren M. (1995). Genes Dev., 9, 2170-2183.
15. Haupt Y, Maya R, Kazaz A and Oren M. (1997). Nature, 387, 296-299.
16. Kinzler KW and Vogelstein B. (1997). Nature, 386, 761-763.
17. Knudson CM, Tung KS, Tourtellotte WG, Brown GA and Korsmeyer SJ. (1995). Science, 270, 96-99.
18. Ko LJ and Prives C. (1996). Genes Dev., 10, 1054-1072.
19. Kubbutat MHG, Jones SN and Vousden KH. (1997). Nature, 387, 299-303.
20. Levine AJ, Perry ME, Chang A, Silver A, Dittmer D, Wu M and Welsh D. (1994). Br. J. Cancer, 69, 409-416.
21. Lowe SW, Jacks T, Housman DE and Ruley HE. (1994). Proc. Natl. Acad. Sci. USA, 91, 2026-2030.
22. Ludwig T, Chapman DL, Papaioannou VE and Efstraliadis A. (1997). Genes Dev., 11, 1126-1241.
23. Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, Liu Q, Cochran C, Bennet LM, Wei D, Bell R, Rosenthal J, Hussey C, Thanh T, McClure M, Frye C, Hattier T, Phelps R, Haugen-Strano A, Katcher H, Kazulo Y, Gholami Z, Shaffer D, Stone S, Bayer S, Wray C, Bogden R, Dayananth P, Ward J, Tonin P, Narod S, Bristow PK, Lai M, Barrett C, Lewis C, Neuhausen S, Cannon-Albright L, Goldger D, Wiseman R, Kamb A and Skolnick MH. (1994). Science, 266, 66-71.
24. Miyashita T and Reed JC. (1995). Cell, 80, 293-299.
25. Neuhausen SL and Marshall CJ. (1994). Cancer Res., 54, 6069-6072.
26. Parker GA, Crook T, Bain M, Sara E, Farrell PJ and Allday MJ. (1996). Oncogene, 13, 2541-2549.
27. Patel KJ, Yu VPCC, Lee H, Corcoran A, Thistlewaite FC, Evans MJ, College WH, Friedman LS, Ponder BAJ and Venkitaraman AR. (1998). Mol. Cell, 1, 347-357.
28. Polyak K, Xia Y, Zweier JL, Kinzler KW and Vogelstein B. (1997). Nature, 389, 300-305.
29. Rowan S, Ludwig RL, Haupt Y, Bates S, Lu X, Oren M and Vousden KH. (1996). EMBO J., 15, 827-838.
30. Smith SA, Easton DF, Evans DGR and Ponder BAJ. (1992). Nature Genetics, 2, 128-131.
31. de Stanchina E, McCurrach ME, Zindy F, Shieh S-Y, Ferheyre G, Samuelson AV, Prives C, Roussel MF, Sherr CJ and Lowe SW. (1998). Genes Dev., 12, 2434-2442.
32. Stott FJ, Bates S, James MC, McConnell BB, Starborg M, Brookes S, Palmero I, Ryan K, Hara E, Vousden KH and Peters G. (1998). EMBO J., 17, 5001-5014.
33. Suzuki A, de la Pompa JL, Hakem R, Elia A, Yoshida R, Mo R, Nishina H, Chuang T, Wakeham A, Itie A, Koo W, Billia P, Ho A, Fukumoto M, Hui CC and Mak TW. (1997). Genes Dev., 11, 1242-1252.
34. The Breast Cancer Linkage Consortium. (1997). Lancet, 349, 1505-1510.
35. Wagner AJ, Kokontis JM and Hay N. (1994). Genes Dev., 8, 2817-2830.
36. Walker KK and Levine AJ. (1996). Proc. Natl. Acad. Sci. USA, 93, 15335-15340.
37. Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, Collins N, Gregory S, Gumbs C, Micklem G, Barfoot R, Hamoudi R, Patel S, Rice C, Biggs P, Hashim Y, Smith A, Connor F, Arason A, Gudmundsson J, Ficenec D, Kelsell D, Ford D, Tonin P, Bishop DT, Spurr N, Ponder BAJ, Eelcs R, Peto J, Devilee P, Cornelisse C, Lynch H, Narod S, Lenoir G, Egilsson V, Barkadottir RB, Easton DF, Bentley DR, Futreal PA, Ashworth A and Stratton MR. (1996). Nature, 378, 789-792.
38. Zhang H, Somasundaram K, Peng Y, Tian H, Zhang H, Bi D, Weber BL and El-Deiry WS. (1998). Oncogene, 16, 1713-1721.
39. Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ and Roussel MF. (1998). Genes Dev., 12, 2424-2433.