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Archives of Biochemistry and Biophysics

Volumn 389, Issue 2, 2001, Pages 264-270

Importance of amino acid residue 474 for substrate specificity of canine and human cytochrome P450 3A enzymes

(3) He, Y Q a Roussel, F a Halpert, J R a

a UNIVERSITY OF TEXAS MEDICAL BRANCH (United States)

Author keywords

CYP3A12; CYP3A26; CYP3A4; Cytochrome P450; Diazepam; Site directed mutagenesis; Steroid hydroxylation

Indexed keywords

AMINO ACID; ANDROSTENEDIONE; CYTOCHROME P450 3A; DIAZEPAM; OXYGENASE; PROGESTERONE; PROLINE; SERINE; TESTOSTERONE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME SPECIFICITY; HUMAN; HYDROXYLATION; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STEREOSPECIFICITY;

STAPHYLOCOCCUS PHAGE 187; STAPHYLOCOCCUS PHAGE 3A;

EID: 27244462519 PISSN: 00039861 EISSN: None Source Type: Journal
DOI: 10.1006/abbi.2001.2342 Document Type: Article

Times cited : (6)

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