Isolation, heterologous expression and functional characterization of a novel cytochrome P450 3A enzyme from a canine liver cDNA library

Journal of Pharmacology and Experimental Therapeutics

Volumn 283, Issue 3, 1997, Pages 1425-1432

  Fraser, David J ^a   Feyereisen, René ^a   Harlow, Greg R ^a   Halpert, James R ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; COMPLEMENTARY DNA; CYTOCHROME P450; PROGESTERONE; STEROID MONOOXYGENASE; TESTOSTERONE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; DNA LIBRARY; DOG; ELECTROPHORETIC MOBILITY; ENZYME ANALYSIS; ENZYME ISOLATION; LIVER; LIVER MICROSOME; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STEROID METABOLISM; STRUCTURE ACTIVITY RELATION; XENOBIOTIC METABOLISM;

AMINO ACID SEQUENCE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BASE SEQUENCE; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DNA, COMPLEMENTARY; DOGS; ESCHERICHIA COLI; GENE LIBRARY; IMMUNOBLOTTING; LIVER; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES, N-DEMETHYLATING; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031459991     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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