Structure-function analysis of human cytochrome P450 3A4 using 7- alkoxycoumarins as active-site probes

Archives of Biochemistry and Biophysics

Volumn 373, Issue 2, 2000, Pages 335-345

  Khan, Kishore K ^a   Halpert, James R ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

7 alkoxycoumarin; Computer modeling; Cytochrome P450 3A4; Electronic influence; Enzymatic constrains

Indexed keywords

COUMARIN DERIVATIVE; CYTOCHROME P450; UMBELLIFERONE DERIVATIVE;

ARTICLE; COMPUTER MODEL; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY;

EID: 0034650844     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1999.1578     Document Type: Article

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