Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum

Neurobiology of Disease

Volumn 20, Issue 2, 2005, Pages 550-561

  Ryu, Jae K ^a   Choi, Hyun B ^a   McLarnon, James G ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Inflammation; Microglia; Neuroprotection; Oxidative damage; Peripheral benzodiazepine receptors; PK11195; Quinolinic acid

Indexed keywords

CASPASE 3; INDUCIBLE NITRIC OXIDE SYNTHASE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; QUINOLINIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CONTROLLED STUDY; CORPUS STRIATUM; DNA DAMAGE; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVATION; IMMUNOCOMPETENT CELL; IMMUNOFLUORESCENCE; LIPID PEROXIDATION; MALE; MICROGLIA; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STATISTICAL SIGNIFICANCE;

ALDEHYDES; ANIMALS; ANTINEOPLASTIC AGENTS; CARRIER PROTEINS; CASPASES; CORPUS STRIATUM; CYTOKINES; DEOXYGUANOSINE; DISEASE MODELS, ANIMAL; ECTODYSPLASINS; ENCEPHALITIS; GLIOSIS; HUNTINGTON DISEASE; ISOQUINOLINES; LIGANDS; MALE; MEMBRANE PROTEINS; MICROGLIA; NERVE DEGENERATION; NEUROTOXINS; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; QUINOLINIC ACID; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; TUMOR NECROSIS FACTORS;

EID: 26944485506     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.04.010     Document Type: Article

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