Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 23, 2005, Pages 5344-5352

  Zbinden, Katrin Groebke ^a   Obst Sander, Ulrike ^a   Hilpert, Kurt ^a   Kühne, Holger ^a   Banner, David W ^a   Böhm, Hans Joachim ^a   Stahl, Martin ^a   Ackermann, Jean ^a   Alig, Leo ^a   Weber, Lutz ^a   Wessel, Hans Peter ^a   Riederer, Markus A ^a   Tschopp, Thomas B ^a   Lavé, Thierry ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 7A INHIBITOR; PHENYLGLYCINE; THROMBOPLASTIN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD CLOTTING; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; INHIBITION KINETICS; NONHUMAN; RAT;

ADMINISTRATION, ORAL; ANIMALS; ANTICOAGULANTS; BIOLOGICAL AVAILABILITY; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; FACTOR VIIA; GLYCINE; HUMANS; MOLECULAR STRUCTURE; RATS; SERINE PROTEINASE INHIBITORS; THROMBOPLASTIN;

EID: 26844500567     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.04.079     Document Type: Article

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