Inhibitors of the tissue factor/factor VIIa-induced coagulation: Synthesis and in vitro evaluation of novel specific 2-aryl substituted 4H-3,1-benzoxazin-4-ones

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 8, 2000, Pages 2095-2103

  Jakobsen, Palle ^a   Ritsmar Pedersen, Bo ^a   Persson, Egon ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

2 ARYL SUBSTITUTED 4H 3,1 BENZOXAZIN 4 ONE DERIVATIVE; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING INHIBITOR; THROMBOPLASTIN; UNCLASSIFIED DRUG;

ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING TIME; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTICOAGULANTS; BLOOD COAGULATION; FACTOR VIIA; FACTOR X; FACTOR XA; HUMANS; MOLECULAR STRUCTURE; OXAZINES; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN; THROMBOPLASTIN;

EID: 0033866734     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00129-2     Document Type: Article

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