An efficient synthesis of 2-(3-(4-amidinophenylcarbamoyl)naphthalen-2-yl)-5-((2,2-methylpro pyl)carbamoyl)benzoic acid: A factor VIIa inhibitor discovered by the Ono Pharmaceutical Company

Tetrahedron Letters

Volumn 41, Issue 32, 2000, Pages 6041-6044

  Kohrt, J T ^a   Filipski, K J ^a   Rapundalo, S T ^a   Cody, W L ^a   Edmunds, J J ^a  

^a PFIZER INC   (United States)

Author keywords

Anticoagulant; Factor VIIa; Palladium catalyzed cross coupling; Stillie coupling

Indexed keywords

2 [3 (4 AMIDINOPHENYLCARBAMOYL)NAPHTHALEN 2 YL] 5 [(2,2 METHYLPROPYL)CARBAMOYL] BENZOIC ACID; ANTICOAGULANT AGENT; BENZOIC ACID DERIVATIVE; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; DRUG SYNTHESIS;

EID: 0034609147     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)01016-9     Document Type: Article

References (22)