Genomic regulatory networks and animal development

Developmental Cell

Volumn 9, Issue 4, 2005, Pages 449-462

  Stathopoulos, Angelike ^a   Levine, Michael ^b  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; GENOMIC DNA; TRANSCRIPTION FACTOR PAX6;

ANIMAL GENETICS; BINDING AFFINITY; BINDING SITE; BIOINFORMATICS; BLASTOMERE; CAENORHABDITIS ELEGANS; CELL CYCLE; DEVELOPMENTAL BIOLOGY; DEVELOPMENTAL GENETICS; DNA BINDING; DNA MICROARRAY; DNA REPLICATION; DROSOPHILA; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; EYE DEVELOPMENT; GASTRULATION; GENE ACTIVITY; GENE CLUSTER; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INTERACTION; GENE LOCATION; GENE TARGETING; GENETIC ANALYSIS; GENETIC CODE; GENETIC TRANSCRIPTION; MOLECULAR MODEL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NOTOCHORD; ORGANOGENESIS; PRIORITY JOURNAL; REPORTER GENE; REVIEW; SIGNAL TRANSDUCTION; TISSUE DIFFERENTIATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BODY PATTERNING; CELL DIFFERENTIATION; CELL LINEAGE; EMBRYO; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; MODELS, GENETIC; MORPHOGENESIS; REGULATORY SEQUENCES, NUCLEIC ACID; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 26444591973     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2005.09.005     Document Type: Review

References (122)

1. Y. Andachi Caenorhabditis elegans T-box genes tbx-9 and tbx-8 are required for formation of hypodermis and body-wall muscle in embryogenesis Genes Cells 9 2004 331-344
2. K.V. Anderson Pinning down positional information: Dorsal-ventral polarity in the Drosophila embryo Cell 95 1998 439-442
3. K. Arora H. Dai S.G. Kazuko J. Jamal M.B. O'Connor A. Letsou and R. Warrior The Drosophila schnürri gene acts in the Dpp/TGF β signaling pathway and encodes a transcription factor homologous to the human MBP family Cell 81 1995 781-790
4. H.L. Ashe and M. Levine Local inhibition and long-range enhancement of Dpp signal transduction by Sog Nature 398 1999 427-431
5. S. Barolo and J.W. Posakony Three habits of highly effective signaling pathways: Principles of transcriptional control by developmental cell signaling Genes Dev. 16 2002 1167-1181
6. L.R. Baugh A.A. Hill J.M. Claggett K. Hill-Harfe J.C. Wen D.K. Slonim E.L. Brown and C.P. Hunter The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo Development 132 2005 1843-1854
7. L.R. Baugh J.C. Wen A.A. Hill D.K. Slonim E.L. Brown and C.P. Hunter Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions Genome Biol. 6 2005 R45
8. E.J. Bellefroid C. Bourguignon T. Hollemann Q. Ma D.J. Anderson C. Kintner and T. Pieler X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiation Cell 87 1996 1191-1202
9. M. Bouchard D. Grote S.E. Craven Q. Sun P. Steinlein and M. Busslinger Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region Development 132 2005 2633-2643
10. S.B. Carroll J.K. Grenier and S.D. Weatherbee From DNA to Diversity: Molecular Genetics and the Evolution of Animal Design 2001 Blackwell Science Malden, MA
11. J. Casal and M. Leptin Identification of novel genes in Drosophila reveals the complex regulation of early gene activity in the mesoderm Proc. Natl. Acad. Sci. USA 93 1996 10327-10332
12. J. Chang I.O. Kim J.S. Ahn and S.H. Kim The CNS midline cells control the spitz class and Egfr signaling genes to establish the proper cell fate of the Drosophila ventral neuroectoderm Int. J. Dev. Biol. 45 2001 715-724
13. K.L. Chow D.H. Hall and S.W. Emmons The mab-21 gene of Caenorhabditis elegans encodes a novel protein required for choice of alternate cell fates Development 121 1995 3615-3626
14. D.E. Clyde M.S. Corado X. Wu A. Pare D. Papatsenko and S. Small A self-organizing system of repressor gradients establishes segmental complexity in Drosophila Nature 426 2003 849-853
15. J.C. Corbo M. Levine and R.W. Zeller Characterization of a notochord-specific enhancer from the Brachyury promoter region of the ascidian, Ciona intestinalis Development 124 1997 589-602
16. J.C. Corbo A. Di Gregorio and M. Levine The ascidian as a model organism in developmental and evolutionary biology Cell 106 2001 535-538
17. R.A. Cornell and T.V. Ohlen Vnd/nkx, ind/gsh, and msh/msx: Conserved regulators of dorsoventral neural patterning? Curr. Opin. Neurobiol. 10 2000 63-71
18. J. Cowden and M. Levine The Snail repressor positions Notch signaling in the Drosophila embryo Development 129 2002 1785-1793
19. J. Cowden and M. Levine Ventral dominance governs sequential patterns of gene expression across the dorsal-ventral axis of the neuroectoderm in the Drosophila embryo Dev. Biol. 262 2003 335-349
20. R.M. Cripps and E.N. Olson Control of cardiac development by an evolutionarily conserved transcriptional network Dev. Biol. 246 2002 14-28
21. E.H. Davidson Genomic Regulatory Systems: Development and Evolution 2001 Academic Press San Diego, CA
22. E.H. Davidson J.P. Rast P. Oliveri A. Ransick C. Calestani C.H. Yuh T. Minokawa G. Amore V. Hinman C. Arenas-Mena et al. A genomic regulatory network for development Science 295 2002 1669-1678
23. A. Di Gregorio and M. Levine Regulation of Ci-tropomyosin-like, a Brachyury target gene in the ascidian, Ciona intestinalis Development 126 1999 5599-5609
24. B.W. Draper C.C. Mello B. Bowerman J. Hardin and J.R. Priess MEX-3 is a KH domain protein that regulates blastomere identity in early C. elegans embryos Cell 87 1996 205-216
25. A. Erives and M. Levine Coordinate enhancers share common organizational features in the Drosophila genome Proc. Natl. Acad. Sci. USA 101 2004 3851-3856
26. A. Fisher and M. Caudy The function of hairy-related bHLH repressor proteins in cell fate decisions Bioessays 20 1998 298-306
27. S. Fujiwara J.C. Corbo and M. Levine The snail repressor establishes a muscle/notochord boundary in the Ciona embryo Development 125 1998 2511-2520
28. L. Gabay H. Scholz M. Golembo A. Klaes B.Z. Shilo and C. Klambt EGF receptor signaling induces pointed P1 transcription and inactivates Yan protein in the Drosophila embryonic ventral ectoderm Development 122 1996 3355-3362
29. L. Gabay R. Seger and B.Z. Shilo In situ activation pattern of Drosophila EGF receptor pathway during development Science 277 1997 1103-1106
30. J. Gaudet and S.E. Mango Regulation of organogenesis by the Caenorhabditis elegans FoxA protein PHA-4 Science 295 2002 821-825
31. J. Gaudet S. Muttumu M. Horner and S.E. Mango Whole-genome analysis of temporal gene expression during foregut development PLoS Biol. 2 2004 e352
32. W.J. Gehring The genetic control of eye development and its implications for the evolution of the various eye-types Int. J. Dev. Biol. 46 2002 65-73
33. L. Gold B. Polisky O. Uhlenbeck and M. Yarus Diversity of oligonucleotide functions Annu. Rev. Biochem. 64 1995 763-797
34. E.S. Green J.L. Stubbs and E.M. Levine Genetic rescue of cell number in a mouse model of microphthalmia: Interactions between Chx10 and G1-phase cell cycle regulators Development 130 2003 539-552
35. N.C. Grieder D. Nellen R. Burke K. Basler and M. Affolter Schnürri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1 Cell 81 1995 791-800
36. K.C. Gunsalus H. Ge A.J. Schetter D.S. Goldberg J.D. Han T. Hao G.F. Berriz N. Bertin J. Huang L.S. Chuang et al. Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis Nature 436 2005 861-865
37. B.P. Gupta and P.W. Sternberg The draft genome sequence of the nematode Caenorhabditis briggsae, a companion to C. elegans Genome Biol. 4 2003 238
38. J. Hatakeyama and R. Kageyama Retinal cell fate determination and bHLH factors Semin. Cell Dev. Biol. 15 2004 83-89
39. E. Hedlund S.L. Karsten L. Kudo D.H. Geschwind and E.M. Carpenter Identification of a Hoxd10-regulated transcriptional network and combinatorial interactions with Hoxa10 during spinal cord development J. Neurosci. Res. 75 2004 307-319
40. V.F. Hinman A.T. Nguyen R.A. Cameron and E.H. Davidson Developmental gene regulatory network architecture across 500 million years of echinoderm evolution Proc. Natl. Acad. Sci. USA 100 2003 13356-13361
41. M.A. Horner S. Quintin M.E. Domeier J. Kimble M. Labouesse and S.E. Mango pha-4, an HNF-3 homolog, specifies pharyngeal organ identity in Caenorhabditis elegans Genes Dev. 12 1998 1947-1952
42. A.M. Huang J. Rusch and M. Levine An anteroposterior Dorsal gradient in the Drosophila embryo Genes Dev. 11 1997 1963-1973
43. N.N. Huang D.E. Mootz A.J. Walhout M. Vidal and C.P. Hunter MEX-3 interacting proteins link cell polarity to asymmetric gene expression in Caenorhabditis elegans Development 129 2002 747-759
44. C.P. Hunter and C. Kenyon Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos Cell 87 1996 217-226
45. D.A. Hutcheson and M.L. Vetter The bHLH factors Xath5 and XNeuroD can upregulate the expression of XBrn3d, a POU-homeodomain transcription factor Dev. Biol. 232 2001 327-338
46. K.S. Imai N. Satoh and Y. Satou Early embryonic expression of FGF4/6/9 gene and its role in the induction of mesenchyme and notochord in Ciona savignyi embryos Development 129 2002 1729-1738
47. T. Inoue M. Wang T.O. Ririe J.S. Fernandes and P.W. Sternberg Transcriptional network underlying Caenorhabditis elegans vulval development Proc. Natl. Acad. Sci. USA 102 2005 4972-4977
48. Y.T. Ip R.E. Park D. Kosman E. Bier and M. Levine The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo Genes Dev. 6 1992 1728-1739
49. J. Jiang and M. Levine Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen Cell 72 1993 741-752
50. J. Jiang D. Kosman Y.T. Ip and M. Levine The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos Genes Dev. 5 1991 1881-1891
51. J.M. Kalb K.K. Lau B. Goszczynski T. Fukushige D. Moons P.G. Okkema and J.D. McGhee pha-4 is Ce-fkh-1, a fork head/HNF-3α,β,γ homolog that functions in organogenesis of the C. elegans pharynx Development 125 1998 2171-2180
52. Y. Kasai S. Stahl and S. Crews Specification of the Drosophila CNS midline cell lineage: Direct control of single-minded transcription by dorsal/ventral patterning genes Gene Expr. 7 1998 171-189
53. J.B. Kearney S.R. Wheeler P. Estes B. Parente and S.T. Crews Gene expression profiling of the developing Drosophila CNS midline cells Dev. Biol. 275 2004 473-492
54. D.N. Keys M. Levine R.M. Harland and J.B. Wallingford Control of intercalation is cell-autonomous in the notochord of Ciona intestinalis Dev. Biol. 246 2002 329-340
55. T. Koide T. Hayata and K.W. Cho Xenopus as a model system to study transcriptional regulatory networks Proc. Natl. Acad. Sci. USA 102 2005 4943-4948
56. D. Kosman Y.T. Ip M. Levine and K. Arora Establishment of the mesoderm-neuroectoderm boundary in the Drosophila embryo Science 254 1991 118-122
57. M. Krause A. Fire S.W. Harrison J. Priess and H. Weintraub CeMyoD accumulation defines the body wall muscle cell fate during C. elegans embryogenesis Cell 63 1990 907-919
58. R. Kraut and M. Levine Mutually repressive interactions between the gap genes giant and Kruppel define middle body regions of the Drosophila embryo Development 111 1991 611-621
59. T. Kusakabe Decoding cis-regulatory systems in ascidians Zoolog. Sci. 22 2005 129-146
60. J. Lee S. Nam S.B. Hwang M. Hong J.Y. Kwon K.S. Joeng S.H. Im J. Shim and M.C. Park Functional genomic approaches using the nematode Caenorhabditis elegans as a model system J. Biochem. Mol. Biol. 37 2004 107-113
61. M. Levine and E.H. Davidson Gene regulatory networks for development Proc. Natl. Acad. Sci. USA 102 2005 4936-4942
62. J. Lo S. Lee M. Xu F. Liu H. Ruan A. Eun Y. He W. Ma W. Wang Z. Wen and J. Peng 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis Genome Res. 13 2003 455-466
63. W.J. Longabaugh E.H. Davidson and H. Bolouri Computational representation of developmental genetic regulatory networks Dev. Biol. 283 2005 1-16
64. M. Maeda H. Sakamoto N. Iranfar D. Fuller T. Maruo S. Ogihara T. Morio H. Urushihara Y. Tanaka and W.F. Loomis Changing patterns of gene expression in Dictyostelium prestalk cell subtypes recognized by in situ hybridization with genes from microarray analyses Eukaryot. Cell 2 2003 627-637
65. S. Mangan and U. Alon Structure and function of the feed-forward loop network motif Proc. Natl. Acad. Sci. USA 100 2003 11980-11985
66. S.E. Mango E.J. Lambie and J. Kimble The pha-4 gene is required to generate the pharyngeal primordium of Caenorhabditis elegans Development 120 1994 3019-3031
67. M. Markstein and M. Levine Decoding cis-regulatory DNAs in the Drosophila genome Curr. Opin. Genet. Dev. 12 2002 601-606
68. M. Markstein P. Markstein V. Markstein and M.S. Levine Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo Proc. Natl. Acad. Sci. USA 99 2002 763-768
69. M. Markstein R. Zinzen P. Markstein K.P. Yee A. Erives A. Stathopoulos and M. Levine A regulatory code for neurogenic gene expression in the Drosophila embryo Development 131 2004 2387-2394
70. T. Marquardt and P. Gruss Generating neuronal diversity in the retina: one for nearly all Trends Neurosci. 25 2002 32-38
71. T. Marquardt R. Ashery-Padan N. Andrejewski R. Scardigli F. Guillemot and P. Gruss Pax6 is required for the multipotent state of retinal progenitor cells Cell 105 2001 43-55
72. L.D. Mathies S.T. Henderson and J. Kimble The C. elegans Hand gene controls embryogenesis and early gonadogenesis Development 130 2003 2881-2892
73. P. Matthias and A.G. Rolink Transcriptional networks in developing and mature B cells Nat. Rev. Immunol. 5 2005 497-508
74. C.C. Mello C. Schubert B. Draper W. Zhang R. Lobel and J.R. Priess The PIE-1 protein and germline specification in C. elegans embryos Nature 382 1996 710-712
75. D. Meulemans and M. Bronner-Fraser Gene-regulatory interactions in neural crest evolution and development Dev. Cell 7 2004 291-299
76. V. Morel and F. Schweisguth Repression by suppressor of hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo Genes Dev. 14 2000 377-388
77. X. Mu and W.H. Klein A gene regulatory hierarchy for retinal ganglion cell specification and differentiation Semin. Cell Dev. Biol. 15 2004 115-123
78. X. Mu P.D. Beremand S. Zhao R. Pershad H. Sun A. Scarpa S. Liang T.L. Thomas and W.H. Klein Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina Development 131 2004 1197-1210
79. X. Mu X. Fu H. Sun P.D. Beremand T.L. Thomas and W.H. Klein A gene network downstream of transcription factor Math5 regulates retinal progenitor cell competence and ganglion cell fate Dev. Biol. 280 2005 467-481
80. Y. Nibu and M.S. Levine CtBP-dependent activities of the short-range Giant repressor in the Drosophila embryo Proc. Natl. Acad. Sci. USA 98 2001 6204-6208
81. H. Nishida and K. Sawada macho-1 encodes a localized mRNA in ascidian eggs that specifies muscle fate during embryogenesis Nature 409 2001 724-729
82. A. Ochoa-Espinosa G. Yucel L. Kaplan A. Pare N. Pura A. Oberstein D. Papatsenko and S. Small The role of binding site cluster strength in Bicoid-dependent patterning in Drosophila Proc. Natl. Acad. Sci. USA 102 2005 4960-4965
83. P. Oliveri and E.H. Davidson Gene regulatory network controlling embryonic specification in the sea urchin Curr. Opin. Genet. Dev. 14 2004 351-360
84. B.D. Page W. Zhang K. Steward T. Blumenthal and J.R. Priess ELT-1, a GATA-like transcription factor, is required for epidermal cell fates in Caenorhabditis elegans embryos Genes Dev. 11 1997 1651-1661
85. D. Papatsenko and M. Levine Computational identification of regulatory DNAs underlying animal development Nat. Methods 2 2005 529-534
86. D. Papatsenko and M. Levine Quantitative analysis of binding motifs mediating diverse spatial readouts of the Dorsal gradient in the Drosophila embryo Proc. Natl. Acad. Sci. USA 102 2005 4966-4971
87. J.C. Pascall J.E. Luck and K.D. Brown Expression in mammalian cell cultures reveals interdependent, but distinct, functions for Star and Rhomboid proteins in the processing of the Drosophila transforming-growth-factor-α homologue Spitz Biochem. J. 363 2002 347-352
88. Y.J. Passamaneck and A. Di Gregorio Ciona intestinalis: Chordate development made simple Dev. Dyn. 233 2005 1-19
89. M. Ptashne A Genetic Switch: Phage Lambda Revisited Third Edition 2004 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY
90. G. Pyrowolakis B. Hartmann B. Muller K. Basler and M. Affolter A simple molecular complex mediates widespread BMP-induced repression during Drosophila development Dev. Cell 7 2004 229-240
91. R.P. Ray K. Arora C. Nusslein-Volhard and W.M. Gelbart The control of cell fate along the dorsal-ventral axis of the Drosophila embryo Development 113 1991 35-54
92. S. Roth The origin of dorsoventral polarity in Drosophila Philos. Trans. R. Soc. Lond. B Biol. Sci. 358 2003 1317-1329
93. S. Roth D. Stein and C. Nusslein-Volhard A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo Cell 59 1989 1189-1202
94. C.A. Rushlow K. Han J.L. Manley and M. Levine The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila Cell 59 1989 1165-1177
95. N. Satoh Y. Satou B. Davidson and M. Levine Ciona intestinalis: An emerging model for whole-genome analyses Trends Genet. 19 2003 376-381
96. K. Senger G.W. Armstrong W.J. Rowell J.M. Kwan M. Markstein and M. Levine Immunity regulatory DNAs share common organizational features in Drosophila Mol. Cell 13 2004 19-32
97. J.M. Servitja and J. Ferrer Transcriptional networks controlling pancreatic development and β cell function Diabetologia 47 2004 597-613
98. G. Seydoux C.C. Mello J. Pettitt W.B. Wood J.R. Priess and A. Fire Repression of gene expression in the embryonic germ lineage of C. elegans Nature 382 1996 713-716
99. D.A. Shaywitz and D.A. Melton The molecular biography of the cell Cell 120 2005 729-731
100. B.Z. Shilo Signaling by the Drosophila epidermal growth factor receptor pathway during development Exp. Cell Res. 284 2003 140-149
101. B.Z. Shilo Regulating the dynamics of EGF receptor signaling in space and time Development 132 2005 4017-4027
102. O. Shimmi D. Umulis H. Othmer and M.B. O'Connor Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo Cell 120 2005 873-886
103. P. Simpson Maternal-zygotic gene interactions during formation of the dorsoventral pattern in Drosophila embryos Genetics 105 1983 615-632
104. H. Singh K.L. Medina and J.M. Pongubala Contingent gene regulatory networks and B cell fate specification Proc. Natl. Acad. Sci. USA 102 2005 4949-4953
105. J.B. Skeath and S. Thor Genetic control of Drosophila nerve cord development Curr. Opin. Neurobiol. 13 2003 8-15
106. A. Stathopoulos and M. Levine Dorsal gradient networks in the Drosophila embryo Dev. Biol. 246 2002 57-67
107. A. Stathopoulos and M. Levine Linear signaling in the Toll-Dorsal pathway of Drosophila: Activated Pelle kinase specifies all threshold outputs of gene expression while the bHLH protein Twist specifies a subset Development 129 2002 3411-3419
108. A. Stathopoulos and M. Levine Whole-genome analysis of Drosophila gastrulation Curr. Opin. Genet. Dev. 14 2004 477-484
109. A. Stathopoulos and M. Levine Localized repressors delineate the neurogenic ectoderm in the early Drosophila embryo Dev. Biol. 280 2005 482-493
110. A. Stathopoulos M. Van Drenth A. Erives M. Markstein and M. Levine Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo Cell 111 2002 687-701
111. R. Steward Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function Cell 59 1989 1179-1188
112. G. Struhl P. Johnston and P.A. Lawrence Control of Drosophila body pattern by the hunchback morphogen gradient Cell 69 1992 237-249
113. J.E. Sulston E. Schierenberg J.G. White and J.N. Thomson The embryonic cell lineage of the nematode Caenorhabditis elegans Dev. Biol. 100 1983 64-119
114. H. Takahashi K. Hotta A. Erives A. Di Gregorio R.W. Zeller M. Levine and N. Satoh Brachyury downstream notochord differentiation in the ascidian embryo Genes Dev. 13 1999 1519-1523
115. R. Tsruya A. Schlesinger A. Reich L. Gabay A. Sapir and B.Z. Shilo Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz Genes Dev. 16 2002 222-234
116. Y.C. Wang and E.L. Ferguson Spatial bistability of Dpp-receptor interactions during Drosophila dorsal-ventral patterning Nature 434 2005 229-234
117. F. Wellmer and J.L. Riechmann Gene network analysis in plant development by genomic technologies Int. J. Dev. Biol. 49 2005 745-759
118. M. Xu N. Kirov and C. Rushlow Peak levels of BMP in the Drosophila embryo control target genes by a feed-forward mechanism Development 132 2005 1637-1647
119. K. Yagi Y. Satou and N. Satoh A zinc finger transcription factor, ZicL, is a direct activator of Brachyury in the notochord specification of Ciona intestinalis Development 131 2004 1279-1288
120. Z. Yang K. Ding L. Pan M. Deng and L. Gan Math5 determines the competence state of retinal ganglion cell progenitors Dev. Biol. 264 2003 240-254
121. H. Zhang M. Levine and H.L. Ashe Brinker is a sequence-specific transcriptional repressor in the Drosophila embryo Genes Dev. 15 2001 261-266
122. G. Zhao and J.B. Skeath The Sox-domain containing gene Dichaete/ fish-hook acts in concert with vnd and ind to regulate cell fate in the Drosophila neuroectoderm Development 129 2002 1165-1174