메뉴 건너뛰기




Volumn 10, Issue 1, 2000, Pages 63-71

Vnd/nkx, ind/gsh, and msh/msx: Conserved regulators of dorsoventral neural patterning?

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN;

EID: 0033957235     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-4388(99)00049-5     Document Type: Review
Times cited : (114)

References (79)
  • 2
    • 0031080963 scopus 로고    scopus 로고
    • Ectodermal patterning in vertebrate embryos
    • Sasai Y., De Robertis E.M. Ectodermal patterning in vertebrate embryos. Dev Biol. 182:1997;5-20.
    • (1997) Dev Biol , vol.182 , pp. 5-20
    • Sasai, Y.1    De Robertis, E.M.2
  • 3
    • 0345552213 scopus 로고    scopus 로고
    • Neural induction. A bird's eye view
    • An excellent review of new data from chick which challenge the hypothesis, based chiefly on results from frogs, that inhibition of BMP signaling is sufficient to 'neuralize' ectodermal cells. The authors review their own discovery that in chick the only ectodermal cells that are competent to respond to exposure to BMP4 inhibitors by expressing neural markers are already close to the neural plate border. They therefore propose that the ectoderm is neuralized by an upstream signaling event that is stabilized by modulation of BMP signaling
    • Streit A., Stern C.D. Neural induction. A bird's eye view. Trends Genet. 15:1999;20-24. An excellent review of new data from chick which challenge the hypothesis, based chiefly on results from frogs, that inhibition of BMP signaling is sufficient to 'neuralize' ectodermal cells. The authors review their own discovery that in chick the only ectodermal cells that are competent to respond to exposure to BMP4 inhibitors by expressing neural markers are already close to the neural plate border. They therefore propose that the ectoderm is neuralized by an upstream signaling event that is stabilized by modulation of BMP signaling.
    • (1999) Trends Genet , vol.15 , pp. 20-24
    • Streit, A.1    Stern, C.D.2
  • 4
    • 0033049093 scopus 로고    scopus 로고
    • Origin of the chordate central nervous system - And the origin of chordates
    • The author uses morphological observations to support his hypothesis that the axis inversion between arthropods and vertebrates happened within the chordate lineage, i.e. later in evolution than others have proposed
    • Nielsen C. Origin of the chordate central nervous system - and the origin of chordates. Dev Genes Evol. 209:1999;198-205. The author uses morphological observations to support his hypothesis that the axis inversion between arthropods and vertebrates happened within the chordate lineage, i.e. later in evolution than others have proposed.
    • (1999) Dev Genes Evol , vol.209 , pp. 198-205
    • Nielsen, C.1
  • 6
    • 0344223266 scopus 로고    scopus 로고
    • Comparison of early nerve cord development in insects and vertebrates
    • A very thorough comparison of the genes controlling neurogenesis, regionalization of the neurectoderm, neural cell type differentiation, and midline cell development in flies and insects. The authors also speculate about the nature of the CNS in the primitive ancestor of the two groups
    • Arendt D., Nubler-Jung K. Comparison of early nerve cord development in insects and vertebrates. Development. 126:1999;2309-2325. A very thorough comparison of the genes controlling neurogenesis, regionalization of the neurectoderm, neural cell type differentiation, and midline cell development in flies and insects. The authors also speculate about the nature of the CNS in the primitive ancestor of the two groups.
    • (1999) Development , vol.126 , pp. 2309-2325
    • Arendt, D.1    Nubler-Jung, K.2
  • 7
    • 0030217951 scopus 로고    scopus 로고
    • Threshold responses to the dorsal regulatory gradient and the subdivision of primary tissue territories in the Drosophila embryo
    • Rusch J., Levine M. Threshold responses to the dorsal regulatory gradient and the subdivision of primary tissue territories in the Drosophila embryo. Curr Opin Genet Dev. 6:1996;416-423.
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 416-423
    • Rusch, J.1    Levine, M.2
  • 8
    • 0029844975 scopus 로고    scopus 로고
    • The Drosophila short gastrulation gene prevents Dpp from autoactivating and suppressing neurogenesis in the neuroectoderm
    • Biehs B., Francois V., Bier E. The Drosophila short gastrulation gene prevents Dpp from autoactivating and suppressing neurogenesis in the neuroectoderm. Genes Dev. 10:1996;2922-2934.
    • (1996) Genes Dev , vol.10 , pp. 2922-2934
    • Biehs, B.1    Francois, V.2    Bier, E.3
  • 9
    • 0344979753 scopus 로고    scopus 로고
    • The role of brinker in mediating the graded response to Dpp in early Drosophila embryos
    • Genetic studies are used to demonstrate the role of brinker (brk) in regulation of Dpp target genes. brk is shown to be expressed in the neurectoderm, and regulated by Dorsal signaling. The authors also demonstrate that brk represses transcription of Dpp targets within the neurectoderm. This suggests that Dorsal, at least in part, acts to specifiy neurectoderm via repression of Dpp signaling
    • Jazwinska A., Rushlow C., Roth S. The role of brinker in mediating the graded response to Dpp in early Drosophila embryos. Development. 126:1999;3323-3334. Genetic studies are used to demonstrate the role of brinker (brk) in regulation of Dpp target genes. brk is shown to be expressed in the neurectoderm, and regulated by Dorsal signaling. The authors also demonstrate that brk represses transcription of Dpp targets within the neurectoderm. This suggests that Dorsal, at least in part, acts to specifiy neurectoderm via repression of Dpp signaling.
    • (1999) Development , vol.126 , pp. 3323-3334
    • Jazwinska, A.1    Rushlow, C.2    Roth, S.3
  • 10
    • 0030219464 scopus 로고    scopus 로고
    • Msh may play a conserved role in dorsoventral patterning of the neuroectoderm and mesoderm
    • D'Alessio M., Frasch M. msh may play a conserved role in dorsoventral patterning of the neuroectoderm and mesoderm. Mech Dev. 58:1996;217-231.
    • (1996) Mech Dev , vol.58 , pp. 217-231
    • D'Alessio, M.1    Frasch, M.2
  • 11
    • 0028135238 scopus 로고
    • The screw gene encodes a ubiquitously expressed member of the TGF-β family required for specification of dorsal cell fates in the Drosophila embryo
    • Arora K., Levine M.S., O'Connor M.B. The screw gene encodes a ubiquitously expressed member of the TGF-β family required for specification of dorsal cell fates in the Drosophila embryo. Genes Dev. 8:1994;2588-2601.
    • (1994) Genes Dev , vol.8 , pp. 2588-2601
    • Arora, K.1    Levine, M.S.2    O'Connor, M.B.3
  • 12
    • 0023186776 scopus 로고
    • Expression of Drosophila epidermal growth factor receptor homologue in mitotic cell populations
    • Kammermeyer K.L., Wadsworth S.C. Expression of Drosophila epidermal growth factor receptor homologue in mitotic cell populations. Development. 100:1987;201-210.
    • (1987) Development , vol.100 , pp. 201-210
    • Kammermeyer, K.L.1    Wadsworth, S.C.2
  • 13
    • 0031666418 scopus 로고    scopus 로고
    • The Drosophila EGF receptor controls the formation and specification along the dorsal-ventral axis of the Drosophila embryo
    • •] demonstrate an early role for Drosophila EgfR in DV patterning within the neurectoderm. In particular, the authors conclude that the intermediate column fails to form, that there is a partial ventral column to dorsal column transformation, and that the dorsal column forms normally in egfR mutants. Thus, the requirement for EgfR in the CNS is specific for the ventral and intermediate columns
    • •] demonstrate an early role for Drosophila EgfR in DV patterning within the neurectoderm. In particular, the authors conclude that the intermediate column fails to form, that there is a partial ventral column to dorsal column transformation, and that the dorsal column forms normally in egfR mutants. Thus, the requirement for EgfR in the CNS is specific for the ventral and intermediate columns.
    • (1998) Development , vol.125 , pp. 3301-3312
    • Skeath, J.B.1
  • 14
    • 0031706418 scopus 로고    scopus 로고
    • Interaction between Drosophila EGF receptor and vnd determines three dorsoventral domains of the neuroectoderm
    • •]
    • •].
    • (1998) Development , vol.125 , pp. 3625-3633
    • Yagi, Y.1    Suzuki, T.2    Hayashi, S.3
  • 15
    • 0033588044 scopus 로고    scopus 로고
    • Reorganizing the organizer 75 years on
    • A review of a meeting at which the most recent advances in investigation of signals that induce and pattern the neurectoderm and mesoderm were discussed
    • Nieto M.A. Reorganizing the organizer 75 years on. Cell. 98:1999;417-425. A review of a meeting at which the most recent advances in investigation of signals that induce and pattern the neurectoderm and mesoderm were discussed.
    • (1999) Cell , vol.98 , pp. 417-425
    • Nieto, M.A.1
  • 16
    • 0031890838 scopus 로고    scopus 로고
    • Chordin regulates primitive streak development and the stability of induced neural cells, but is not sufficient for neural induction in the chick embryo
    • Streit A., Lee K.J., Woo I., Roberts C., Jessell T.M., Stern C.D. Chordin regulates primitive streak development and the stability of induced neural cells, but is not sufficient for neural induction in the chick embryo. Development. 125:1998;507-519.
    • (1998) Development , vol.125 , pp. 507-519
    • Streit, A.1    Lee, K.J.2    Woo, I.3    Roberts, C.4    Jessell, T.M.5    Stern, C.D.6
  • 17
    • 0033015433 scopus 로고    scopus 로고
    • Establishment and maintenance of the border of the neural plate in the chick: Involvement of FGF and BMP activity
    • Streit A., Stern C.D. Establishment and maintenance of the border of the neural plate in the chick: involvement of FGF and BMP activity. Mech Dev. 82:1999;51-66.
    • (1999) Mech Dev , vol.82 , pp. 51-66
    • Streit, A.1    Stern, C.D.2
  • 18
    • 0029162584 scopus 로고
    • Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm
    • Liem K.F. Jr., Tremml G., Roelink H., Jessell T.M. Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell. 82:1995;969-979.
    • (1995) Cell , vol.82 , pp. 969-979
    • Liem, K.F.1    Tremml, G.2    Roelink, H.3    Jessell, T.M.4
  • 19
    • 0029013039 scopus 로고
    • Localized BMP-4 mediates dorsal/ventral patterning in the early Xenopus embryo
    • Schmidt J.E., Suzuki A., Ueno N., Kimelman D. Localized BMP-4 mediates dorsal/ventral patterning in the early Xenopus embryo. Dev Biol. 169:1995;37-50.
    • (1995) Dev Biol , vol.169 , pp. 37-50
    • Schmidt, J.E.1    Suzuki, A.2    Ueno, N.3    Kimelman, D.4
  • 20
    • 0029802904 scopus 로고    scopus 로고
    • Genetic analysis of dorsoventral pattern formation in the zebrafish: Requirement of a BMP-like ventralizing activity and its dorsal repressor
    • Hammerschmidt M., Serbedzija G.N., McMahon A.P. Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor. Genes Dev. 10:1996;2452-2461.
    • (1996) Genes Dev , vol.10 , pp. 2452-2461
    • Hammerschmidt, M.1    Serbedzija, G.N.2    McMahon, A.P.3
  • 21
    • 0031712371 scopus 로고    scopus 로고
    • BMPs, Smads and metalloproteases: Extracellular and intracellular modes of negative regulation
    • Cho K.W., Blitz I.L. BMPs, Smads and metalloproteases: extracellular and intracellular modes of negative regulation. Curr Opin Genet Dev. 8:1998;443-449.
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 443-449
    • Cho, K.W.1    Blitz, I.L.2
  • 22
    • 0033580437 scopus 로고    scopus 로고
    • Brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes
    • The authors show that injection of RNA encoding fly brinker into X. laevis embryos counteracts the ventralizing effect of co-injected RNA encoding BMP4. Fly brinker RNA also induces neural genes in explanted X. laevis ectoderm. These results suggest that a brinker homologue exists in vertebrates, where it may inhibit BMP activated genes
    • Minami M., Kinoshita N., Kamoshida Y., Tanimoto H., Tabata T. brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes. Nature. 398:1999;242-246. The authors show that injection of RNA encoding fly brinker into X. laevis embryos counteracts the ventralizing effect of co-injected RNA encoding BMP4. Fly brinker RNA also induces neural genes in explanted X. laevis ectoderm. These results suggest that a brinker homologue exists in vertebrates, where it may inhibit BMP activated genes.
    • (1999) Nature , vol.398 , pp. 242-246
    • Minami, M.1    Kinoshita, N.2    Kamoshida, Y.3    Tanimoto, H.4    Tabata, T.5
  • 23
    • 0030837822 scopus 로고    scopus 로고
    • The role in neural patterning of translation initiation factor eIF4AII; Induction of neural fold genes
    • Morgan R., Sargent M.G. The role in neural patterning of translation initiation factor eIF4AII; induction of neural fold genes. Development. 124:1997;2751-2760.
    • (1997) Development , vol.124 , pp. 2751-2760
    • Morgan, R.1    Sargent, M.G.2
  • 24
    • 0032525780 scopus 로고    scopus 로고
    • The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradient
    • Marchant L., Linker C., Ruiz P., Guerrero N., Mayor R. The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradient. Dev Biol. 198:1998;319-329.
    • (1998) Dev Biol , vol.198 , pp. 319-329
    • Marchant, L.1    Linker, C.2    Ruiz, P.3    Guerrero, N.4    Mayor, R.5
  • 25
    • 0030886059 scopus 로고    scopus 로고
    • Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1
    • Wilson P.A., Lagna G., Suzuki A., Hemmati-Brivanlou A. Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1. Development. 124:1997;3177-3184.
    • (1997) Development , vol.124 , pp. 3177-3184
    • Wilson, P.A.1    Lagna, G.2    Suzuki, A.3    Hemmati-Brivanlou, A.4
  • 26
    • 0030744740 scopus 로고    scopus 로고
    • Mechanisms of dorsal-ventral patterning in noggin-induced neural tissue
    • Knecht A.K., Harland R.M. Mechanisms of dorsal-ventral patterning in noggin-induced neural tissue. Development. 124:1997;2477-2488.
    • (1997) Development , vol.124 , pp. 2477-2488
    • Knecht, A.K.1    Harland, R.M.2
  • 27
    • 0032608362 scopus 로고    scopus 로고
    • Development of neural crest in Xenopus
    • While chiefly reviewing induction of neural crest, the authors propose that BMP activity levels may direct patterning at all DV positions within the neurectoderm
    • Mayor R., Young R., Vargas A. Development of neural crest in Xenopus. Curr Top Dev Biol. 43:1999;85-113. While chiefly reviewing induction of neural crest, the authors propose that BMP activity levels may direct patterning at all DV positions within the neurectoderm.
    • (1999) Curr Top Dev Biol , vol.43 , pp. 85-113
    • Mayor, R.1    Young, R.2    Vargas, A.3
  • 28
    • 0032607866 scopus 로고    scopus 로고
    • Embryonic axis formation in the zebrafish
    • Mullins M.C. Embryonic axis formation in the zebrafish. Methods Cell Biol. 59:1999;159-178.
    • (1999) Methods Cell Biol , vol.59 , pp. 159-178
    • Mullins, M.C.1
  • 29
    • 0030964620 scopus 로고    scopus 로고
    • Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4
    • Suzuki A., Ueno N., Hemmati-Brivanlou A. Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4. Development. 124:1997;3037-3044.
    • (1997) Development , vol.124 , pp. 3037-3044
    • Suzuki, A.1    Ueno, N.2    Hemmati-Brivanlou, A.3
  • 30
    • 0030708635 scopus 로고    scopus 로고
    • The molecular nature of zebrafish swirl: BMP2 function is essential during early dorsoventral patterning
    • Kishimoto Y., Lee K.H., Zon L., Hammerschmidt M., Schulte-Merker S. The molecular nature of zebrafish swirl: BMP2 function is essential during early dorsoventral patterning. Development. 124:1997;4457-4466.
    • (1997) Development , vol.124 , pp. 4457-4466
    • Kishimoto, Y.1    Lee, K.H.2    Zon, L.3    Hammerschmidt, M.4    Schulte-Merker, S.5
  • 31
    • 0032127505 scopus 로고    scopus 로고
    • Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes
    • From analysis of mutants in the BMP pathway, the authors propose that a gradient of BMP activity directly imparts at least three fates in zebrafish ectodermal: epidermis, neural crest, and non-dorsal CNS
    • Nguyen V.H., Schmid B., Trout J., Connors S.A., Ekker M., Mullins M.C. Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes. Dev Biol. 199:1998;93-110. From analysis of mutants in the BMP pathway, the authors propose that a gradient of BMP activity directly imparts at least three fates in zebrafish ectodermal: epidermis, neural crest, and non-dorsal CNS.
    • (1998) Dev Biol , vol.199 , pp. 93-110
    • Nguyen, V.H.1    Schmid, B.2    Trout, J.3    Connors, S.A.4    Ekker, M.5    Mullins, M.C.6
  • 33
    • 0033405806 scopus 로고    scopus 로고
    • Bmp activity establishes a gradient of positional information throughout the entire neural plate
    • •] by showing that markers of interneurons are expanded in zebrafish mutants of the BMP pathway. Motorneurons are not obviously increased in numbers in these embryos; however, their position is shifted slightly laterally, which is consistent with the possibility that BMP signaling directly influences cell fate across the entire DV axis of the neural plate. The authors show that anterior-posterior patterning is not grossly affected in the BMP pathway mutants
    • •] by showing that markers of interneurons are expanded in zebrafish mutants of the BMP pathway. Motorneurons are not obviously increased in numbers in these embryos; however, their position is shifted slightly laterally, which is consistent with the possibility that BMP signaling directly influences cell fate across the entire DV axis of the neural plate. The authors show that anterior-posterior patterning is not grossly affected in the BMP pathway mutants.
    • (1999) Development , vol.126 , pp. 4977-4987
    • Barth, K.A.1    Kishimoto, Y.2    Rohr, K.B.3    Seydler, C.4    Schulte-Merker, S.5    Wilson, S.W.6
  • 34
    • 0033010962 scopus 로고    scopus 로고
    • The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo
    • Hild M., Dick A., Rauch G.J., Meier A., Bouwmeester T., Haffter P., Hammerschmidt M. The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo. Development. 126:1999;2149-2159.
    • (1999) Development , vol.126 , pp. 2149-2159
    • Hild, M.1    Dick, A.2    Rauch, G.J.3    Meier, A.4    Bouwmeester, T.5    Haffter, P.6    Hammerschmidt, M.7
  • 36
    • 0031901224 scopus 로고    scopus 로고
    • Neural crest induction in Xenopus: Evidence for a two-signal model
    • LaBonne C., Bronner-Fraser M. Neural crest induction in Xenopus: evidence for a two-signal model. Development. 125:1998;2403-2414.
    • (1998) Development , vol.125 , pp. 2403-2414
    • Labonne, C.1    Bronner-Fraser, M.2
  • 37
    • 0033566848 scopus 로고    scopus 로고
    • Expression of Pax-3 in the lateral neural plate is dependent on a Wnt- mediated signal from posterior nonaxial mesoderm
    • Bang A.G., Papalopulu N., Goulding M.D., Kintner C. Expression of Pax-3 in the lateral neural plate is dependent on a Wnt- mediated signal from posterior nonaxial mesoderm. Dev Biol. 212:1999;366-380.
    • (1999) Dev Biol , vol.212 , pp. 366-380
    • Bang, A.G.1    Papalopulu, N.2    Goulding, M.D.3    Kintner, C.4
  • 38
    • 0034112411 scopus 로고    scopus 로고
    • Dorsal and intermediate neuronal cell types of the spinal cord are established by a BMP signaling pathway
    • in press
    • Nguyen V.H., Trout J., Connors S.A., Andermann P., Weinberg E., Mullins M.C. Dorsal and intermediate neuronal cell types of the spinal cord are established by a BMP signaling pathway. Development. 2000;. in press.
    • (2000) Development
    • Nguyen, V.H.1    Trout, J.2    Connors, S.A.3    Andermann, P.4    Weinberg, E.5    Mullins, M.C.6
  • 39
    • 0033603209 scopus 로고    scopus 로고
    • A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord
    • Pierani A., Brenner-Morton S., Chiang C., Jessell T.M. A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord. Cell. 97:1999;903-915.
    • (1999) Cell , vol.97 , pp. 903-915
    • Pierani, A.1    Brenner-Morton, S.2    Chiang, C.3    Jessell, T.M.4
  • 40
    • 0029068123 scopus 로고
    • Sonic hedgehog induces the differentiation of ventral forebrain neurons: A common signal for ventral patterning within the neural tube
    • Ericson J., Muhr J., Placzek M., Lints T., Jessell T.M., Edlund T. Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for ventral patterning within the neural tube. Cell. 81:1995;747-756.
    • (1995) Cell , vol.81 , pp. 747-756
    • Ericson, J.1    Muhr, J.2    Placzek, M.3    Lints, T.4    Jessell, T.M.5    Edlund, T.6
  • 41
    • 0029075802 scopus 로고
    • Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain
    • Barth K.A., Wilson S.W. Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain. Development. 121:1995;1755-1768.
    • (1995) Development , vol.121 , pp. 1755-1768
    • Barth, K.A.1    Wilson, S.W.2
  • 43
    • 0032033034 scopus 로고    scopus 로고
    • Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development
    • Qiu M., Shimamura K., Sussel L., Chen S., Rubenstein J.L. Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development. Mech Dev. 72:1998;77-88.
    • (1998) Mech Dev , vol.72 , pp. 77-88
    • Qiu, M.1    Shimamura, K.2    Sussel, L.3    Chen, S.4    Rubenstein, J.L.5
  • 45
    • 0030584081 scopus 로고    scopus 로고
    • Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity
    • Ericson J., Morton S., Kawakami A., Roelink H., Jessell T.M. Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity. Cell. 87:1996;661-673.
    • (1996) Cell , vol.87 , pp. 661-673
    • Ericson, J.1    Morton, S.2    Kawakami, A.3    Roelink, H.4    Jessell, T.M.5
  • 46
    • 0029019627 scopus 로고
    • Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants
    • Marti E., Bumcrot D.A., Takada R., McMahon A.P. Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants. Nature. 375:1995;322-325.
    • (1995) Nature , vol.375 , pp. 322-325
    • Marti, E.1    Bumcrot, D.A.2    Takada, R.3    McMahon, A.P.4
  • 47
    • 0026474841 scopus 로고
    • Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila
    • Mohler J., Vani K. Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila. Development. 115:1992;957-971.
    • (1992) Development , vol.115 , pp. 957-971
    • Mohler, J.1    Vani, K.2
  • 48
    • 0026783674 scopus 로고
    • Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog
    • Lee J.J., von Kessler D.P., Parks S., Beachy P.A. Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog. Cell. 71:1992;33-50.
    • (1992) Cell , vol.71 , pp. 33-50
    • Lee, J.J.1    Von Kessler, D.P.2    Parks, S.3    Beachy, P.A.4
  • 49
    • 0032559307 scopus 로고    scopus 로고
    • Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation
    • Zhang J., Talbot W.S., Schier A.F. Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation. Cell. 92:1998;241-251.
    • (1998) Cell , vol.92 , pp. 241-251
    • Zhang, J.1    Talbot, W.S.2    Schier, A.F.3
  • 50
    • 0031040286 scopus 로고    scopus 로고
    • The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail
    • Schier A.F., Neuhauss S.C., Helde K.A., Talbot W.S., Driever W. The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail. Development. 124:1997;327-342.
    • (1997) Development , vol.124 , pp. 327-342
    • Schier, A.F.1    Neuhauss, S.C.2    Helde, K.A.3    Talbot, W.S.4    Driever, W.5
  • 51
    • 0031107682 scopus 로고    scopus 로고
    • One-eyed pinhead is required for development of the ventral midline of the zebrafish (Danio rerio) neural tube
    • Strahle U., Jesuthasan S., Blader P., Garcia-Villalba P., Hatta K., Ingham P.W. one-eyed pinhead is required for development of the ventral midline of the zebrafish (Danio rerio) neural tube. Genes Funct. 1:1997;131-148.
    • (1997) Genes Funct , vol.1 , pp. 131-148
    • Strahle, U.1    Jesuthasan, S.2    Blader, P.3    Garcia-Villalba, P.4    Hatta, K.5    Ingham, P.W.6
  • 52
    • 0029015431 scopus 로고
    • Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination
    • Schweitzer R., Shaharabany M., Seger R., Shilo B-Z. Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination. Genes Dev. 9:1995;1518-1529.
    • (1995) Genes Dev , vol.9 , pp. 1518-1529
    • Schweitzer, R.1    Shaharabany, M.2    Seger, R.3    Shilo, B.-Z.4
  • 53
    • 0032533601 scopus 로고    scopus 로고
    • Dorsoventral patterning in the Drosophila central nervous system: The vnd homeobox gene specifies ventral column identity
    • The authors show that a ventral to intermediate fate change occurs in vnd mutant embryos, and that misexpression of vnd results in conversion of more dorsal columns to a ventral fate, establishing a hierarchy among the DV column genes
    • McDonald J.A., Holbrook S., Isshiki T., Weiss J., Doe C.Q., Mellerick D.M. Dorsoventral patterning in the Drosophila central nervous system: the vnd homeobox gene specifies ventral column identity. Genes Dev. 12:1998;3603-3612. The authors show that a ventral to intermediate fate change occurs in vnd mutant embryos, and that misexpression of vnd results in conversion of more dorsal columns to a ventral fate, establishing a hierarchy among the DV column genes.
    • (1998) Genes Dev , vol.12 , pp. 3603-3612
    • McDonald, J.A.1    Holbrook, S.2    Isshiki, T.3    Weiss, J.4    Doe, C.Q.5    Mellerick, D.M.6
  • 54
    • 0032533213 scopus 로고    scopus 로고
    • Dorsoventral patterning in the Drosophila central nervous system: The intermediate neuroblasts defective homeobox gene specifies intermediate column identity
    • The authors report the cloning and characterization of the homeobox-containing gene ind in Drosophila. The study shows an essential role for ind in the formation and specification of the intermediate column neuroblasts and their progeny. These results establish similar function for ind in the intermediate column, as was previously known for vnd and msh in their respective columns. Furthermore, the authors provide evidence that a transcriptional hierarchy exists between the three DV column genes
    • Weiss J.B., Von Ohlen T., Mellerick D.M., Dressler G., Doe C.Q., Scott M.P. Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity. Genes Dev. 12:1998;3591-3602. The authors report the cloning and characterization of the homeobox-containing gene ind in Drosophila. The study shows an essential role for ind in the formation and specification of the intermediate column neuroblasts and their progeny. These results establish similar function for ind in the intermediate column, as was previously known for vnd and msh in their respective columns. Furthermore, the authors provide evidence that a transcriptional hierarchy exists between the three DV column genes.
    • (1998) Genes Dev , vol.12 , pp. 3591-3602
    • Weiss, J.B.1    Von Ohlen, T.2    Mellerick, D.M.3    Dressler, G.4    Doe, C.Q.5    Scott, M.P.6
  • 56
    • 0031042084 scopus 로고    scopus 로고
    • Mutations in lottchen cause cell fate transformations in neuroblast and glioblast lineages in the Drosophila embryonic central nervous system
    • Buescher M., Chia W. Mutations in lottchen cause cell fate transformations in neuroblast and glioblast lineages in the Drosophila embryonic central nervous system. Development. 124:1997;673-681.
    • (1997) Development , vol.124 , pp. 673-681
    • Buescher, M.1    Chia, W.2
  • 57
    • 0030982569 scopus 로고    scopus 로고
    • The role of the msh homeobox gene during Drosophila neurogenesis: Implication for the dorsoventral specification of the neuroectoderm
    • Isshiki T., Takeichi M., Nose A. The role of the msh homeobox gene during Drosophila neurogenesis: implication for the dorsoventral specification of the neuroectoderm. Development. 124:1997;3099-3109.
    • (1997) Development , vol.124 , pp. 3099-3109
    • Isshiki, T.1    Takeichi, M.2    Nose, A.3
  • 58
    • 0031805560 scopus 로고    scopus 로고
    • Demarcation of ventral territories by the homeobox gene NKX2.1 during early chick development
    • Pera E.M., Kessel M. Demarcation of ventral territories by the homeobox gene NKX2.1 during early chick development. Dev Genes Evol. 208:1998;168-171.
    • (1998) Dev Genes Evol , vol.208 , pp. 168-171
    • Pera, E.M.1    Kessel, M.2
  • 60
    • 0345195959 scopus 로고    scopus 로고
    • Nkx2-9 is a novel homeobox transcription factor which demarcates ventral domains in the developing mouse CNS
    • Pabst O., Herbrand H., Arnold H.H. Nkx2-9 is a novel homeobox transcription factor which demarcates ventral domains in the developing mouse CNS. Mech Dev. 73:1998;85-93.
    • (1998) Mech Dev , vol.73 , pp. 85-93
    • Pabst, O.1    Herbrand, H.2    Arnold, H.H.3
  • 64
    • 0031866767 scopus 로고    scopus 로고
    • Expression domains of the medaka (Oryzias latipes) Ol-Gsh 1 gene are reminiscent of those of clustered and orphan homeobox genes
    • Deschet K., Bourrat F., Chourrout D., Joly J.S. Expression domains of the medaka (Oryzias latipes) Ol-Gsh 1 gene are reminiscent of those of clustered and orphan homeobox genes. Dev Genes Evol. 208:1998;235-244.
    • (1998) Dev Genes Evol , vol.208 , pp. 235-244
    • Deschet, K.1    Bourrat, F.2    Chourrout, D.3    Joly, J.S.4
  • 65
    • 0028292605 scopus 로고
    • Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development
    • Satokata I., Maas R. Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development. Nat Genet. 6:1994;348-356.
    • (1994) Nat Genet , vol.6 , pp. 348-356
    • Satokata, I.1    Maas, R.2
  • 66
    • 0030219763 scopus 로고    scopus 로고
    • Msx3: A novel murine homologue of the Drosophila msh homeobox gene restricted to the dorsal embryonic central nervous system
    • Wang W., Chen X., Xu H., Lufkin T. Msx3: a novel murine homologue of the Drosophila msh homeobox gene restricted to the dorsal embryonic central nervous system. Mech Dev. 58:1996;203-215.
    • (1996) Mech Dev , vol.58 , pp. 203-215
    • Wang, W.1    Chen, X.2    Xu, H.3    Lufkin, T.4
  • 67
    • 0030899176 scopus 로고    scopus 로고
    • Disruption of Msx-1 and Msx-2 reveals roles for these genes in craniofacial, eye, and axial development
    • Foerst-Potts L., Sadler T.W. Disruption of Msx-1 and Msx-2 reveals roles for these genes in craniofacial, eye, and axial development. Dev Dyn. 209:1997;70-84.
    • (1997) Dev Dyn , vol.209 , pp. 70-84
    • Foerst-Potts, L.1    Sadler, T.W.2
  • 68
    • 0033560895 scopus 로고    scopus 로고
    • Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
    • The authors show that while ventral neural progenitors form in a mouse mutant of nkx2.2, they give rise to cell types normally generated only in more dorsal progenitor cells. However, in this mutant some derivatives of the nkx2.2-expressing cells in the hindbrain form normally, which they speculate may be due to a redundant function of nkx2.9 expressed there
    • Briscoe J., Sussel L., Serup P., Hartigan-O'Connor D., Jessell T.M., Rubenstein J.L., Ericson J. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature. 398:1999;622-627. The authors show that while ventral neural progenitors form in a mouse mutant of nkx2.2, they give rise to cell types normally generated only in more dorsal progenitor cells. However, in this mutant some derivatives of the nkx2.2-expressing cells in the hindbrain form normally, which they speculate may be due to a redundant function of nkx2.9 expressed there.
    • (1999) Nature , vol.398 , pp. 622-627
    • Briscoe, J.1    Sussel, L.2    Serup, P.3    Hartigan-O'Connor, D.4    Jessell, T.M.5    Rubenstein, J.L.6    Ericson, J.7
  • 69
    • 0032841612 scopus 로고    scopus 로고
    • Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: Evidence for a transformation of the pallidum into the striatum
    • Through analysis of a number of molecular markers, the authors argue that the forebrain phenotypes of a mouse missing nkx2.1 function result from a transformation of the pallidal primordium into a more dorsal forebrain derivative, the striatum
    • Sussel L., Marin O., Kimura S., Rubenstein J.L. Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development. 126:1999;3359-3370. Through analysis of a number of molecular markers, the authors argue that the forebrain phenotypes of a mouse missing nkx2.1 function result from a transformation of the pallidal primordium into a more dorsal forebrain derivative, the striatum.
    • (1999) Development , vol.126 , pp. 3359-3370
    • Sussel, L.1    Marin, O.2    Kimura, S.3    Rubenstein, J.L.4
  • 70
    • 0026346213 scopus 로고
    • Genetic control of primary neuronal development in zebrafish
    • Suppl(2)
    • Kimmel C.B., Hatta K., Eisen J.S. Genetic control of primary neuronal development in zebrafish. Development. 1991;47-57. Suppl(2).
    • (1991) Development , pp. 47-57
    • Kimmel, C.B.1    Hatta, K.2    Eisen, J.S.3
  • 71
    • 0033168891 scopus 로고    scopus 로고
    • Patterning motoneurons in the vertebrate nervous system
    • Eisen J.S. Patterning motoneurons in the vertebrate nervous system. Trends Neurosci. 22:1999;321-326.
    • (1999) Trends Neurosci , vol.22 , pp. 321-326
    • Eisen, J.S.1
  • 72
    • 0030579127 scopus 로고    scopus 로고
    • The embryonic central nervous system lineages of Drosophila melanogaster. I. Neuroblast lineages derived from the ventral half of the neuroectoderm
    • Bossing T., Udolph G., Doe C.Q., Technau G.M. The embryonic central nervous system lineages of Drosophila melanogaster. I. Neuroblast lineages derived from the ventral half of the neuroectoderm. Dev Biol. 179:1996;41-64.
    • (1996) Dev Biol , vol.179 , pp. 41-64
    • Bossing, T.1    Udolph, G.2    Doe, C.Q.3    Technau, G.M.4
  • 73
    • 0031572234 scopus 로고    scopus 로고
    • The embryonic central nervous system lineages of Drosophila melanogaster. II. Neuroblast lineages derived from the dorsal part of the neuroectoderm
    • Schmidt H., Rickert C., Bossing T., Vef O., Urban J., Technau G.M. The embryonic central nervous system lineages of Drosophila melanogaster. II. Neuroblast lineages derived from the dorsal part of the neuroectoderm. Dev Biol. 189:1997;186-204.
    • (1997) Dev Biol , vol.189 , pp. 186-204
    • Schmidt, H.1    Rickert, C.2    Bossing, T.3    Vef, O.4    Urban, J.5    Technau, G.M.6
  • 74
    • 0032707248 scopus 로고    scopus 로고
    • Clonal analysis of Drosophila embryonic neuroblasts: Neural cell types, axon projections and muscle targets
    • This is the most comprehensive study of insect neuroblast lineages. It seeks to resolve discrepancies of previous studies by unambiguous identification of neuroblasts and by analyzing clones very late in embryonic development. This study reveals novel cell types and axon/dendrite complexity, and identifies muscle targets for all motoneurons
    • Schmid A., Chiba A., Doe C.Q. Clonal analysis of Drosophila embryonic neuroblasts: neural cell types, axon projections and muscle targets. Development. 126:1999;4653-4689. This is the most comprehensive study of insect neuroblast lineages. It seeks to resolve discrepancies of previous studies by unambiguous identification of neuroblasts and by analyzing clones very late in embryonic development. This study reveals novel cell types and axon/dendrite complexity, and identifies muscle targets for all motoneurons.
    • (1999) Development , vol.126 , pp. 4653-4689
    • Schmid, A.1    Chiba, A.2    Doe, C.Q.3
  • 75
    • 0030004542 scopus 로고    scopus 로고
    • Regulation of vertebrate neural cell fate by transcription factors
    • Bang A.G., Goulding M.D. Regulation of vertebrate neural cell fate by transcription factors. Curr Opin Neurobiol. 6:1996;25-32.
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 25-32
    • Bang, A.G.1    Goulding, M.D.2
  • 76
    • 0032966338 scopus 로고    scopus 로고
    • Control of neurogenesis - lessons from frogs, fish and flies
    • Chitnis A.B. Control of neurogenesis - lessons from frogs, fish and flies. Curr Opin Neurobiol. 9:1999;18-25.
    • (1999) Curr Opin Neurobiol , vol.9 , pp. 18-25
    • Chitnis, A.B.1
  • 78
    • 0028605603 scopus 로고
    • Temporal colinearity and the phylotypic progression: A basis for the stability of a vertebrate Bauplan and the evolution of morphologies through heterochrony
    • Duboule D. Temporal colinearity and the phylotypic progression: a basis for the stability of a vertebrate Bauplan and the evolution of morphologies through heterochrony. Dev Suppl. 1994;135-142.
    • (1994) Dev Suppl , pp. 135-142
    • Duboule, D.1
  • 79
    • 0033166286 scopus 로고    scopus 로고
    • Vertebrate evolution: The developmental origins of adult variation
    • Richardson M.K. Vertebrate evolution: the developmental origins of adult variation. Bioessays. 21:1999;604-613.
    • (1999) Bioessays , vol.21 , pp. 604-613
    • Richardson, M.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.