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Volumn 87, Issue 2, 1996, Pages 205-216

MEX-3 is a KH domain protein that regulates blastomere identity in early C. elegans embryos

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN MEX3; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 0030592578     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81339-2     Document Type: Article
Times cited : (228)

References (46)
  • 1
    • 0021364821 scopus 로고
    • Formation of the first cleavage spindle in nematode embryos
    • Albertson, D.G. (1984). Formation of the first cleavage spindle in nematode embryos. Dev. Biol. 101, 61-72.
    • (1984) Dev. Biol. , vol.101 , pp. 61-72
    • Albertson, D.G.1
  • 2
    • 0027377580 scopus 로고
    • FMR1 protein: Conserved RNP family domains and selective RNA binding
    • Ashley, C.T., Jr., Wilkinson, K.D., Reines, D., and Warren, S.T. (1993). FMR1 protein: conserved RNP family domains and selective RNA binding. Science 262, 563-566.
    • (1993) Science , vol.262 , pp. 563-566
    • Ashley, C.T.1    Wilkinson, K.D.2    Reines, D.3    Warren, S.T.4
  • 3
    • 0028104274 scopus 로고
    • Formation of a monomeric DNA binding domain by Skn-1 bZIP and homeodomain elements
    • Blackwell, T.K., Bowerman, B., Priess, J.R., and Weintraub, H. (1994). Formation of a monomeric DNA binding domain by Skn-1 bZIP and homeodomain elements. Science 266, 621-628.
    • (1994) Science , vol.266 , pp. 621-628
    • Blackwell, T.K.1    Bowerman, B.2    Priess, J.R.3    Weintraub, H.4
  • 4
    • 0026529831 scopus 로고
    • skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. Elegans embryo
    • Bowerman, B., Eaton, B.A., and Priess, J.R. (1992). skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo. Cell 68, 1061-1075.
    • (1992) Cell , vol.68 , pp. 1061-1075
    • Bowerman, B.1    Eaton, B.A.2    Priess, J.R.3
  • 5
    • 0027209420 scopus 로고
    • The maternal gene skn-1 encodes a protein that is distributed unequally in early C. Elegans embryos
    • Bowerman, B., Draper, B.W., Mello, C.M., and Priess, J.R. (1993). The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos. Cell 74, 443-452.
    • (1993) Cell , vol.74 , pp. 443-452
    • Bowerman, B.1    Draper, B.W.2    Mello, C.M.3    Priess, J.R.4
  • 6
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner, S. (1974). The genetics of Caenorhabditis elegans. Genetics 77, 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 7
    • 0028843197 scopus 로고
    • Control of cleavage spindle orientation in Caenorhabditis elegans: The role of the genes par-2 and par-3
    • Cheng, N.N., Kirby, C.M., and Kemphues, K.J. (1995). Control of cleavage spindle orientation in Caenorhabditis elegans: the role of the genes par-2 and par-3. Genetics 139, 549-559.
    • (1995) Genetics , vol.139 , pp. 549-559
    • Cheng, N.N.1    Kirby, C.M.2    Kemphues, K.J.3
  • 8
    • 0022006433 scopus 로고
    • Mapping the distribution of differentiation potential for intestine, muscle, and hypodermis during early development in Caenorhabditis elegans
    • Cowan, A.E., and McIntosh, J.R. (1985). Mapping the distribution of differentiation potential for intestine, muscle, and hypodermis during early development in Caenorhabditis elegans. Cell 41, 923-932.
    • (1985) Cell , vol.41 , pp. 923-932
    • Cowan, A.E.1    McIntosh, J.R.2
  • 9
    • 0028843736 scopus 로고
    • Asymmetric distribution of PAR-3 protein contributes to cell polarity and spindle alignment in early C. Elegans embryos
    • Etemad-Moghadam, B., Guo, S., and Kemphues, K.J. (1995). Asymmetric distribution of PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos. Cell 83, 743-752.
    • (1995) Cell , vol.83 , pp. 743-752
    • Etemad-Moghadam, B.1    Guo, S.2    Kemphues, K.J.3
  • 10
    • 0028217190 scopus 로고
    • Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. Elegans embryo
    • Evans, T.C., Crittenden, S.L., Kodoyianni, V., and Kimble, J. (1994). Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryo. Cell 77, 183-194.
    • (1994) Cell , vol.77 , pp. 183-194
    • Evans, T.C.1    Crittenden, S.L.2    Kodoyianni, V.3    Kimble, J.4
  • 11
    • 0027260844 scopus 로고
    • KH domains within the FMR1 sequence suggest that fragile X syndrome stems from a defect in RNA metabolism
    • Gibson, T.J., Rice, P.M., Thompson, J.D., and Heringa, J. (1993). KH domains within the FMR1 sequence suggest that fragile X syndrome stems from a defect in RNA metabolism. Trends Biochem. Sci. 18, 331-333.
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 331-333
    • Gibson, T.J.1    Rice, P.M.2    Thompson, J.D.3    Heringa, J.4
  • 12
    • 0029024475 scopus 로고
    • par-1, a gene required for establishing polarity in C. Elegans embryos, encodes a putative Ser/ Thr kinase that is asymmetrically distributed
    • Guo, S., and Kemphues, K.J. (1995). par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/ Thr kinase that is asymmetrically distributed. Cell 81, 611-620.
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 13
    • 0003448569 scopus 로고
    • Cold Spring Harbor, New York: Cold Spring Harbor Laboratory
    • Harlow, E., and Lane, D. (1988). Antibodies: A Laboratory Manual (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory).
    • (1988) Antibodies: A Laboratory Manual
    • Harlow, E.1    Lane, D.2
  • 14
    • 0026763373 scopus 로고
    • The genelin-3 encodes an inductive signal for vulval development in C. Elegans
    • Hill, R., and Sternberg, P. (1992). The genelin-3 encodes an inductive signal for vulval development in C. elegans. Nature 358, 470-476.
    • (1992) Nature , vol.358 , pp. 470-476
    • Hill, R.1    Sternberg, P.2
  • 15
    • 0030592556 scopus 로고    scopus 로고
    • Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. Elegans embryos
    • this issue
    • Hunter, C.P., and Kenyon, C. (1996). Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos. Cell, this issue.
    • (1996) Cell
    • Hunter, C.P.1    Kenyon, C.2
  • 16
    • 0028343269 scopus 로고
    • glp-1 and inductions establishing embryonic axis in Caenorhabditis elegans
    • Hutter, H., and Schnabel, R. (1994). glp-1 and inductions establishing embryonic axis in Caenorhabditis elegans. Development 120, 2051-2064.
    • (1994) Development , vol.120 , pp. 2051-2064
    • Hutter, H.1    Schnabel, R.2
  • 17
    • 0028365490 scopus 로고
    • Clonal characterization of a single-stranded DNA binding protein that specifically recognizes deoxycytidine stretch
    • Ito, K., Sato, K., and Endo, H. (1994). Clonal characterization of a single-stranded DNA binding protein that specifically recognizes deoxycytidine stretch. Nucleic Acids Res. 22, 53-58.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 53-58
    • Ito, K.1    Sato, K.2    Endo, H.3
  • 18
    • 0029015430 scopus 로고
    • Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affects a conserved domain also found in Src-associated protein Sam68
    • Jones, A.R., and Schedl, T. (1995). Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affects a conserved domain also found in Src-associated protein Sam68. Genes Dev. 9, 1491-1504.
    • (1995) Genes Dev. , vol.9 , pp. 1491-1504
    • Jones, A.R.1    Schedl, T.2
  • 19
    • 0024284814 scopus 로고
    • Identification of genes required for cytoplasmic localization in early C. Elegans embryos
    • Kemphues, K.J., Priess, J.R., Morton, D.G., and Cheng, N. (1988). Identification of genes required for cytoplasmic localization in early C. elegans embryos. Cell 52, 311-320.
    • (1988) Cell , vol.52 , pp. 311-320
    • Kemphues, K.J.1    Priess, J.R.2    Morton, D.G.3    Cheng, N.4
  • 20
    • 0025123656 scopus 로고
    • Mutations in the par genes of Caenorhabditis elegans affect cytoplasmic reorganization during the first cell cycle
    • Kirby, C., Kusch, M., and Kemphues, K. (1990). Mutations in the par genes of Caenorhabditis elegans affect cytoplasmic reorganization during the first cell cycle. Dev. Biol. 142, 203-215.
    • (1990) Dev. Biol. , vol.142 , pp. 203-215
    • Kirby, C.1    Kusch, M.2    Kemphues, K.3
  • 21
    • 0023659440 scopus 로고
    • A trans-spliced leader sequence on actin mRNA in C. Elegans
    • Krause, M., and Hirsh, D. (1987). A trans-spliced leader sequence on actin mRNA in C. elegans. Cell 49, 753-761.
    • (1987) Cell , vol.49 , pp. 753-761
    • Krause, M.1    Hirsh, D.2
  • 22
    • 0018841583 scopus 로고
    • Segregation of developmental potential in early embryos of Caenorhabditis elegans
    • Laufer, J.S., Bazzicalupo, P., and Wood, W.B. (1980). Segregation of developmental potential in early embryos of Caenorhabditis elegans. Cell 19, 569-577.
    • (1980) Cell , vol.19 , pp. 569-577
    • Laufer, J.S.1    Bazzicalupo, P.2    Wood, W.B.3
  • 23
    • 0029076374 scopus 로고
    • Characterization of two major cellular poly(rC)-binding human proteins each containing three K-homology (KH) domains
    • Leffers, H., Dejgaard, K., and Celis, J.E. (1995). Characterization of two major cellular poly(rC)-binding human proteins each containing three K-homology (KH) domains. Eur. J. Biochem. 230, 447-453.
    • (1995) Eur. J. Biochem. , vol.230 , pp. 447-453
    • Leffers, H.1    Dejgaard, K.2    Celis, J.E.3
  • 24
    • 0028783457 scopus 로고
    • pop-1 encodes an HMG box protein required for specification of a mesodermal precursor in early C. Elegans embryos
    • Lin, R., Thompson, S., and Priess, J.R. (1995). pop-1 encodes an HMG box protein required for specification of a mesodermal precursor in early C. elegans embryos. Cell 83, 599-609.
    • (1995) Cell , vol.83 , pp. 599-609
    • Lin, R.1    Thompson, S.2    Priess, J.R.3
  • 25
    • 0028932769 scopus 로고
    • NusA contacts nascent RNA in Escherichia coli transcription complexes
    • Liu, K., and Hanna, M.M. (1995). NusA contacts nascent RNA in Escherichia coli transcription complexes. J. Mol. Biol. 247, 547-558.
    • (1995) J. Mol. Biol. , vol.247 , pp. 547-558
    • Liu, K.1    Hanna, M.M.2
  • 26
    • 0029030017 scopus 로고
    • Localized Bicaudal-C RNA encodes a protein containing a KH domain, the RNA binding motif of FMR1
    • Mahone, M., Saffman, E.E., and Lasko, P.F. (1995). Localized Bicaudal-C RNA encodes a protein containing a KH domain, the RNA binding motif of FMR1. EMBO J. 14, 2043-2055.
    • (1995) EMBO J. , vol.14 , pp. 2043-2055
    • Mahone, M.1    Saffman, E.E.2    Lasko, P.F.3
  • 27
    • 0028064630 scopus 로고
    • Two maternal genes, apx-1 and pie-1, are required to distinguish the fates of equivalent blastomeres in the early Caenorhabditis elegans embryo
    • Mango, S.E., Thorpe, C.J., Martin, P.R., Chamberlain, S.H., and Bowerman, B. (1994). Two maternal genes, apx-1 and pie-1, are required to distinguish the fates of equivalent blastomeres in the early Caenorhabditis elegans embryo. Development 120, 2305-2315.
    • (1994) Development , vol.120 , pp. 2305-2315
    • Mango, S.E.1    Thorpe, C.J.2    Martin, P.R.3    Chamberlain, S.H.4    Bowerman, B.5
  • 28
    • 0026651316 scopus 로고
    • The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. Elegans embryos
    • Mello, C.C., Draper, B.W., Krause, M., Weintraub, H., and Priess, J.R. (1992). The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos. Cell 70, 163-176.
    • (1992) Cell , vol.70 , pp. 163-176
    • Mello, C.C.1    Draper, B.W.2    Krause, M.3    Weintraub, H.4    Priess, J.R.5
  • 29
    • 0029815260 scopus 로고    scopus 로고
    • The PIE-1 protein and germline specification in early C. Elegans embryos
    • Mello, C.C., Schubert, C., Draper, B., Zhang, W., Lobel, B., and Priess, J.R. (1996). The PIE-1 protein and germline specification in early C. elegans embryos. Nature 382, 710-712.
    • (1996) Nature , vol.382 , pp. 710-712
    • Mello, C.C.1    Schubert, C.2    Draper, B.3    Zhang, W.4    Lobel, B.5    Priess, J.R.6
  • 30
    • 0029945359 scopus 로고    scopus 로고
    • An inductive interaction in 4-cell stage C. Elegans embryos involves APX-1 expression in the signaling cell
    • Mickey, K.M., Mello, C.C., Montgomery, M.K., Fire, A., and Priess, J.R. (1996). An inductive interaction in 4-cell stage C. elegans embryos involves APX-1 expression in the signaling cell. Development 122, 1791-1798.
    • (1996) Development , vol.122 , pp. 1791-1798
    • Mickey, K.M.1    Mello, C.C.2    Montgomery, M.K.3    Fire, A.4    Priess, J.R.5
  • 31
    • 0020825822 scopus 로고
    • Differential localization of two myosins within nematode thick filaments
    • Miller, D.M., Ill, Oritz, I., Berliner, G.C., and Epstein, H.F. (1983). Differential localization of two myosins within nematode thick filaments. Cell 34, 477-490.
    • (1983) Cell , vol.34 , pp. 477-490
    • Miller D.M. III1    Oritz, I.2    Berliner, G.C.3    Epstein, H.F.4
  • 32
    • 0024099699 scopus 로고
    • Analysis of a mutator activity necessary for germline transposition and excision of Tc1 transposable elements in Caenorhabditis elegans
    • Mori, I., Moerman, G., and Waterston, R.H. (1988). Analysis of a mutator activity necessary for germline transposition and excision of Tc1 transposable elements in Caenorhabditis elegans. Genetics 120, 397-407.
    • (1988) Genetics , vol.120 , pp. 397-407
    • Mori, I.1    Moerman, G.2    Waterston, R.H.3
  • 33
    • 0026773728 scopus 로고
    • par-4, a gene required for cytoplasmic localization and determination of specific cell types in Caenorhabditis elegans embryogenesis
    • Morton, D.G., Roos, J.M., and Kemphues, K.J. (1992). par-4, a gene required for cytoplasmic localization and determination of specific cell types in Caenorhabditis elegans embryogenesis. Genetics 130, 771-790.
    • (1992) Genetics , vol.130 , pp. 771-790
    • Morton, D.G.1    Roos, J.M.2    Kemphues, K.J.3
  • 34
    • 0029988528 scopus 로고    scopus 로고
    • Three-dimensional structure and stability of the KH domain: Molecular insights into the Fragile X syndrome
    • Musco, G., Stier, G., Joseph, C., Morelli, M.A.C., Nilges, M., Gibson, T., and Pastore, A. (1996). Three-dimensional structure and stability of the KH domain: molecular insights into the Fragile X syndrome. Cell 85, 237-245.
    • (1996) Cell , vol.85 , pp. 237-245
    • Musco, G.1    Stier, G.2    Joseph, C.3    Morelli, M.A.C.4    Nilges, M.5    Gibson, T.6    Pastore, A.7
  • 35
    • 0023667756 scopus 로고
    • Cellular interactions in early C. Elegans embryos
    • Priess, J.R., and Thomson, J.N. (1987). Cellular interactions in early C. elegans embryos. Cell 48, 241-250.
    • (1987) Cell , vol.48 , pp. 241-250
    • Priess, J.R.1    Thomson, J.N.2
  • 36
    • 0028329199 scopus 로고
    • Autonomous and nonautonomy in cell fate specification of muscle in the C. Elegans embryo: A reciprocal induction
    • Schnabel, R. (1994). Autonomous and nonautonomy in cell fate specification of muscle in the C. elegans embryo: a reciprocal induction. Science 263, 1449-1452.
    • (1994) Science , vol.263 , pp. 1449-1452
    • Schnabel, R.1
  • 37
    • 0030197603 scopus 로고    scopus 로고
    • Pattern formation: Regional specification in the early C. Elegans embryo
    • Schnabel, R. (1996). Pattern formation: regional specification in the early C. elegans embryo. Bioessays 18, 591-594.
    • (1996) Bioessays , vol.18 , pp. 591-594
    • Schnabel, R.1
  • 38
    • 0029670718 scopus 로고    scopus 로고
    • mex-1 and the general partitioning of cell fate in the early C. Elegans embryo
    • Schnabel, R., Weigner, C., Hutter, H., Feichtinger, R., and Schnabel, H. (1996). mex-1 and the general partitioning of cell fate in the early C. elegans embryo. Mech. Dev. 54, 133-147.
    • (1996) Mech. Dev. , vol.54 , pp. 133-147
    • Schnabel, R.1    Weigner, C.2    Hutter, H.3    Feichtinger, R.4    Schnabel, H.5
  • 39
    • 0028114328 scopus 로고
    • Soma-germline asymmetry in the distribution of embryonic RNAs in Caenorhabditis elegans
    • Seydoux, G., and Fire, A. (1994). Soma-germline asymmetry in the distribution of embryonic RNAs in Caenorhabditis elegans. Development 120, 2823-2834.
    • (1994) Development , vol.120 , pp. 2823-2834
    • Seydoux, G.1    Fire, A.2
  • 40
    • 0027273728 scopus 로고
    • The pre-mRNA binding K protein contains a novel evolutionarily conserved motif
    • Siomi, H., Matunis, M.J., Michael, W.M., and Dreyfuss, G. (1993). The pre-mRNA binding K protein contains a novel evolutionarily conserved motif. Nucleic Acids Res. 21, 1193-1198.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 1193-1198
    • Siomi, H.1    Matunis, M.J.2    Michael, W.M.3    Dreyfuss, G.4
  • 41
    • 0028236525 scopus 로고
    • Essential role for KH domains in RNA binding: Impaired RNA binding by mutations in the KH domain of FMR1 that causes fragile X syndrome
    • Siomi, H., Choi, M., Siomi, M.C., Nussbaum., R.L., and Dreyfuss, G. (1994). Essential role for KH domains in RNA binding: impaired RNA binding by mutations in the KH domain of FMR1 that causes fragile X syndrome. Cell 77, 33-39.
    • (1994) Cell , vol.77 , pp. 33-39
    • Siomi, H.1    Choi, M.2    Siomi, M.C.3    Dreyfuss, G.4
  • 42
    • 0027166660 scopus 로고
    • Operons in C. Elegans: Polycistronic mRNA precursors are processed by trans-splicing of SL2 to downstream coding regions
    • Spieth, J., Brooke, G., Kuersten, S., Lea, K., and Blumenthal, T. (1993). Operons in C. elegans: polycistronic mRNA precursors are processed by trans-splicing of SL2 to downstream coding regions. Cell 73, 521-532.
    • (1993) Cell , vol.73 , pp. 521-532
    • Spieth, J.1    Brooke, G.2    Kuersten, S.3    Lea, K.4    Blumenthal, T.5
  • 43
    • 0009656730 scopus 로고
    • Immunofluorescence visualization of germ-line-specific cytoplasmic granules in embryos, larvae, and adults of Caenorhabditis elegans
    • Strome, S., and Wood, W.B. (1982). Immunofluorescence visualization of germ-line-specific cytoplasmic granules in embryos, larvae, and adults of Caenorhabditis elegans. Proc. Natl. Acad. Sci. 79, 1558-1562.
    • (1982) Proc. Natl. Acad. Sci. , vol.79 , pp. 1558-1562
    • Strome, S.1    Wood, W.B.2
  • 44
    • 0020858899 scopus 로고
    • The embryonic cell lineage of the nematode Caenorhabditis elegans
    • Sulston, J.E., Schierenberg, E., White, J.G., and Thomson, J.N. (1983). The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev. Biol. 100, 64-119.
    • (1983) Dev. Biol. , vol.100 , pp. 64-119
    • Sulston, J.E.1    Schierenberg, E.2    White, J.G.3    Thomson, J.N.4
  • 45
    • 0029087624 scopus 로고
    • Protein-rRNA binding features and their structural and functional implications in ribosomes as determined by cross-linking studies
    • Urlaub, H., Kruft, V., Bischof, O., Mueller, E.C., and Whittman-Liebold, B. (1995). Protein-rRNA binding features and their structural and functional implications in ribosomes as determined by cross-linking studies. EMBO J. 14, 4578-4588.
    • (1995) EMBO J. , vol.14 , pp. 4578-4588
    • Urlaub, H.1    Kruft, V.2    Bischof, O.3    Mueller, E.C.4    Whittman-Liebold, B.5
  • 46
    • 0025872516 scopus 로고
    • Regulation of cellular responsiveness to inductive signals in the developing C. Elegans nervous system
    • Waring, D.A., and Kenyon, C. (1991). Regulation of cellular responsiveness to inductive signals in the developing C. elegans nervous system. Nature 350, 712-715.
    • (1991) Nature , vol.350 , pp. 712-715
    • Waring, D.A.1    Kenyon, C.2


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