Persistent expression of Hlxb9 in the pancreatic epithelium impairs pancreatic development

Developmental Biology

Volumn 240, Issue 1, 2001, Pages 247-253

  Li, Hao ^a   Edlund, Helena ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

Hlxb9; Homeobox gene; Intestinal differentiation; Ipf1; Pancreatic agenesis; Pdx1; Temporal regulation

Indexed keywords

ALPHA ACTIN; HOMEODOMAIN PROTEIN; PROTEIN HB9; UNCLASSIFIED DRUG;

AGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; ENDOCRINE CELL; EPITHELIUM; EXOCRINE CELL; GENE EXPRESSION REGULATION; HOMEOBOX; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MESENCHYME; MORPHOGENESIS; MOUSE; NONHUMAN; PANCREAS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; TRANSGENIC MOUSE;

MUS MUSCULUS;

EID: 0035584535     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2001.0440     Document Type: Article

References (24)

1. The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in PDX1/IPF1-deficient mice
2. Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
3. Notch-signalling controls pancreatic cell fate differentiation
4. Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity
5. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo
6. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
7. Transcribing pancreas
8. Analysis of endoderm formation in the avian blastoderm by the use of quail-chick chimaeras. The problem of the neurectodermal origin of the cells of the APUD series
9. A novel human homeobox gene distantly related to proboscipedia is expressed in lymphoid and pancreatic tissues
10. Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice
11. Notochord repression of endodermal Sonic hedgehog permits pancreas development
12. Smooth muscle actin expression during rat gut development and induction in fetal skin fibroblastic cells associated with intestinal embryonic epithelium
13. Notochord to endoderm signaling is required for pancreas development
14. Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor
15. The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein
16. The bHLH protein PTF1-48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas
17. Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9
18. IPF1, a homeodomain-containing transactivator of the insulin gene
19. Development of the embryonic endocrine pancreas
20. The neural crest and the origin of the insulin-producing and other gastrointestinal hormone producing cells
21. A homeobox gene, HLXB9, is the major locus for dominantly inherited sacral agenesis
22. The concentric structure of the developing gut is regulated by Sonic hedgehog from endodermal epithelium
23. The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat