메뉴 건너뛰기




Volumn 7, Issue 5, 2000, Pages 806-812

Enhanced green fluorescent protein fusion proteins of herpes simplex virus type 1 thymidine kinase and cytochrome P450 4B1: Applications for prodrug-activating gene therapy

Author keywords

Cytochrome P450; Gene therapy; Glioma; Green fluorescent protein; Herpes simplex virus type 1 thymidine kinase

Indexed keywords

4 IPOMEANOL; CYTOCHROME P450; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PRODRUG; THYMIDINE KINASE; VIRUS VECTOR;

EID: 0034102736     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700173     Document Type: Article
Times cited : (28)

References (22)
  • 2
    • 0022485359 scopus 로고
    • Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
    • Moolten FL. Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res. 1986;46: 5276-5281.
    • (1986) Cancer Res. , vol.46 , pp. 5276-5281
    • Moolten, F.L.1
  • 3
    • 0031463632 scopus 로고    scopus 로고
    • Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
    • Ram Z, Culver KW, Oshiro EM, et al. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nat Med. 1997;3:1354-1361.
    • (1997) Nat Med. , vol.3 , pp. 1354-1361
    • Ram, Z.1    Culver, K.W.2    Oshiro, E.M.3
  • 4
    • 0017097077 scopus 로고
    • Role of metabolic activation in the pathogenesis of chemically induced pulmonary disease: Mechanism of action of the lung-toxic furan, 4-ipomeanol
    • Boyd MR. Role of metabolic activation in the pathogenesis of chemically induced pulmonary disease: mechanism of action of the lung-toxic furan, 4-ipomeanol. Environ Health Perspect. 1976;16:127-138.
    • (1976) Environ Health Perspect. , vol.16 , pp. 127-138
    • Boyd, M.R.1
  • 5
    • 0025949636 scopus 로고
    • Metabolic activation of 4-ipomeanol by complementary DNA-expressed human cytochromes P-450: Evidence for species-specific metabolism
    • Czerwinski M, McLemore TL, Philpot RM, et al. Metabolic activation of 4-ipomeanol by complementary DNA-expressed human cytochromes P-450: evidence for species-specific metabolism. Cancer Res. 1991;51:4636-4638.
    • (1991) Cancer Res. , vol.51 , pp. 4636-4638
    • Czerwinski, M.1    McLemore, T.L.2    Philpot, R.M.3
  • 6
    • 0032503657 scopus 로고    scopus 로고
    • New prodrug activation gene therapy for cancer using cyto-chrome P450 4B1 and 2-aminoanthracene/4-ipomeanol
    • Rainov NG, Dobberstein KU, Sena-Esteves M, et al. New prodrug activation gene therapy for cancer using cyto-chrome P450 4B1 and 2-aminoanthracene/4-ipomeanol. Hum Gene Ther. 1998;9:1261-1273.
    • (1998) Hum Gene Ther. , vol.9 , pp. 1261-1273
    • Rainov, N.G.1    Dobberstein, K.U.2    Sena-Esteves, M.3
  • 8
    • 15444351633 scopus 로고    scopus 로고
    • Green fluorescent protein as a reporter for retrovirus and helper virus-free HSV-1 amplicon vector-mediated gene transfer into neural cells in culture and in vivo
    • Aboody-Guterman KS, Pechan PA, Rainov NG, et al. Green fluorescent protein as a reporter for retrovirus and helper virus-free HSV-1 amplicon vector-mediated gene transfer into neural cells in culture and in vivo. Neuroreport. 1997;8:3801-3808.
    • (1997) Neuroreport , vol.8 , pp. 3801-3808
    • Aboody-Guterman, K.S.1    Pechan, P.A.2    Rainov, N.G.3
  • 9
    • 0031970741 scopus 로고    scopus 로고
    • Herpes simplex virus thymidine kinase-green fluorescent protein fusion gene: New tool for gene transfer studies and gene therapy
    • Loimas S, Wahlfors J, Janne J. Herpes simplex virus thymidine kinase-green fluorescent protein fusion gene: new tool for gene transfer studies and gene therapy. Biotechniques. 1998;24:614-618.
    • (1998) Biotechniques , vol.24 , pp. 614-618
    • Loimas, S.1    Wahlfors, J.2    Janne, J.3
  • 10
    • 0033139768 scopus 로고    scopus 로고
    • Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: Implications for noninvasive imaging of transgene expression
    • Jacobs A, Dubrovin M, Hewett J, et al. Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: Implications for noninvasive imaging of transgene expression. Neoplasia. 1999;1:154-161.
    • (1999) Neoplasia , vol.1 , pp. 154-161
    • Jacobs, A.1    Dubrovin, M.2    Hewett, J.3
  • 11
    • 0041603456 scopus 로고    scopus 로고
    • A chimeric fusion protein of cytochrome CYP4B1 and green fluorescent protein for detection of pro-drug activating gene delivery and for gene therapy in malignant glioma
    • Walden PTU, Sterry W, Farzaneh F, eds. New York: Plenum Press
    • Rainov NG, Dobberstein KU, Sena-Esteves M, et al. A chimeric fusion protein of cytochrome CYP4B1 and green fluorescent protein for detection of pro-drug activating gene delivery and for gene therapy in malignant glioma. In: Walden PTU, Sterry W, Farzaneh F, eds. Gene Therapy of Cancer. 1st ed. New York: Plenum Press; 1998:393-404.
    • (1998) Gene Therapy of Cancer. 1st Ed. , pp. 393-404
    • Rainov, N.G.1    Dobberstein, K.U.2    Sena-Esteves, M.3
  • 12
    • 0025241769 scopus 로고
    • Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors
    • Moolten FL, Wells JM. Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors. J Natl Cancer Inst. 1990;82:297-300.
    • (1990) J Natl Cancer Inst. , vol.82 , pp. 297-300
    • Moolten, F.L.1    Wells, J.M.2
  • 13
    • 0025352187 scopus 로고
    • Advanced mammalian gene transfer: High-titer retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
    • Morgenstern JP, Land H. Advanced mammalian gene transfer: high-titer retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 1990;18:3587-3696.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3587-3696
    • Morgenstern, J.P.1    Land, H.2
  • 15
    • 0014949207 scopus 로고
    • Cleavage of structure proteins during the assembly of the head of bacteriophage T4
    • Laemmli U. Cleavage of structure proteins during the assembly of the head of bacteriophage T4. Nature. 1970; 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.1
  • 16
    • 0019551730 scopus 로고
    • "Western blotting": Electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A
    • Burnette WN. "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem. 1981;112:195-203.
    • (1981) Anal Biochem. , vol.112 , pp. 195-203
    • Burnette, W.N.1
  • 17
    • 0019789164 scopus 로고
    • Herpes-specific and α DNA polymerase in nuclear envelope of BHK infected cells
    • Herzberg M, Bibor-Hardy V, Simard R. Herpes-specific and α DNA polymerase in nuclear envelope of BHK infected cells. Biochem Biophys Res Commun. 1981;100: 644-650.
    • (1981) Biochem Biophys Res Commun. , vol.100 , pp. 644-650
    • Herzberg, M.1    Bibor-Hardy, V.2    Simard, R.3
  • 18
    • 0023447836 scopus 로고
    • Evidence that deletion of coding sequences in the 5′ end of the thymidine kinase gene of herpes simplex virus type 1 affects the stability of the gene products
    • Haarr L, Flatmark T. Evidence that deletion of coding sequences in the 5′ end of the thymidine kinase gene of herpes simplex virus type 1 affects the stability of the gene products. J Gen Virol. 1987;68:2817-2829.
    • (1987) J Gen Virol. , vol.68 , pp. 2817-2829
    • Haarr, L.1    Flatmark, T.2
  • 19
    • 0024370045 scopus 로고
    • Primary structures of cytochrome P-450 isozyme 5 from rabbit and rat and regulation of species-dependent expression and induction in lung and liver: Identification of cytochrome P-450 gene subfamily IVB
    • Gasser R, Philpot RM. Primary structures of cytochrome P-450 isozyme 5 from rabbit and rat and regulation of species-dependent expression and induction in lung and liver: identification of cytochrome P-450 gene subfamily IVB. Mol Pharmacol. 1989;35:617-625.
    • (1989) Mol Pharmacol. , vol.35 , pp. 617-625
    • Gasser, R.1    Philpot, R.M.2
  • 21
    • 0033004469 scopus 로고    scopus 로고
    • Enrichment of transiently transfected mesangial cells by cell sorting after cotransfection with GFP
    • Chen R, Greene EL, Collinsworth G, et al. Enrichment of transiently transfected mesangial cells by cell sorting after cotransfection with GFP. Am J Physiol. 1999;276:F777-F785.
    • (1999) Am J Physiol. , vol.276
    • Chen, R.1    Greene, E.L.2    Collinsworth, G.3
  • 22
    • 0033591006 scopus 로고    scopus 로고
    • Rapid selection of tetracycline-controlled inducible cell lines using a green fluorescent-transactivator fusion protein
    • Callus BA, Mathey-Prevot B. Rapid selection of tetracycline-controlled inducible cell lines using a green fluorescent-transactivator fusion protein. Biochem Biophys Res Commun. 1999;257:874-878.
    • (1999) Biochem Biophys Res Commun. , vol.257 , pp. 874-878
    • Callus, B.A.1    Mathey-Prevot, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.