Combined chemotherapy of murine mammary tumors by local activation of the prodrugs ifosfamide and 5-fluorocytosine

Cancer Gene Therapy

Volumn 7, Issue 4, 2000, Pages 629-636

  Kammertoens, Thomas ^a   Gelbmann, Wolfgang ^b   Karle, Peter ^b   Alton, Klemens ^b   Saller, Robert ^c   Salmons, Brian ^c   Günzburg, Walter H ^b   Uckert, Wolfgang ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^c Bavarian Nordic GmbH   (Germany)

Author keywords

Cytochrome P450 2B1; Cytosine deaminase; Gene therapy; Suicide genes

Indexed keywords

CYTOCHROME P450 2B1; CYTOCHROME P450 ISOENZYME; CYTOSINE DEAMINASE; DRUG METABOLITE; FLUCYTOSINE; IFOSFAMIDE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST TUMOR; CANCER COMBINATION CHEMOTHERAPY; CANCER THERAPY; CONTROLLED STUDY; DRUG ACTIVATION; DRUG EFFICACY; FEMALE; GENE THERAPY; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUICIDE GENE; TREATMENT OUTCOME;

ANIMALIA; FELIS CATUS; MURINAE;

EID: 0034115137     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700139     Document Type: Article

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