Ion channels and intracellular signaling proteins as potential targets for novel therapeutics for addictive and depressive disorders

Pharmacology and Therapeutics

Volumn 108, Issue 1 SPEC. ISS., 2005, Pages 65-75

  Bonci, Antonello ^a,b   Carlezon Jr , William A ^c  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MCLEAN HOSPITAL   (United States)

Author keywords

Addiction; Depression; Intracellular; Ion channels; Models; Signal transduction pathways

Indexed keywords

4 AMINOPYRIDINE; ALCOHOL; AMPHETAMINE; ANTIDEPRESSANT AGENT; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; COCAINE; CONOTOXIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DILTIAZEM; DOPAMINE; DYNORPHIN; G PROTEIN COUPLED RECEPTOR; INWARDLY RECTIFYING POTASSIUM CHANNEL; ION CHANNEL; KAPPA OPIATE RECEPTOR ANTAGONIST; METHYLPHENIDATE; MORPHINE; MUTANT PROTEIN; NALOXONE; PHOSPHODIESTERASE INHIBITOR; POTASSIUM CHANNEL; ROLIPRAM; VOLTAGE GATED POTASSIUM CHANNEL;

ACTION POTENTIAL; ADDICTION; ALCOHOL CONSUMPTION; ANGINA PECTORIS; CALCIUM CURRENT; CALCIUM TRANSPORT; COCAINE DEPENDENCE; DEPRESSION; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DRUG EFFECT; DRUG EFFICACY; DRUG TARGETING; DYSPHORIA; ENZYME ACTIVITY; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; HUMAN; HYPERPOLARIZATION; HYPERTENSION; ION CONDUCTANCE; LEARNING; LIMBIC CORTEX; MAZE TEST; MEMORY; MOLECULAR MECHANICS; NERVE CELL PLASTICITY; NEUROPROTECTION; NEUROTRANSMISSION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; NUCLEUS ACCUMBENS; POTASSIUM CURRENT; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; PYRAMIDAL NERVE CELL; REVIEW; SIGNAL TRANSDUCTION; STRESS; SUBSTANTIA NIGRA; SYNAPTIC TRANSMISSION; WITHDRAWAL SYNDROME;

EID: 25444439820     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2005.06.020     Document Type: Review

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