-
3
-
-
0033179904
-
Functional dissociation of mu opioid receptor signaling and endocytosis: Implications for the biology of opiate tolerance and addiction
-
Whistler J.L., et al. Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. Neuron. 23:1999;737-746.
-
(1999)
Neuron
, vol.23
, pp. 737-746
-
-
Whistler, J.L.1
-
4
-
-
0034619796
-
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
-
Bohn L.M., et al. μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence. Nature. 408:2000;720-723.
-
(2000)
Nature
, vol.408
, pp. 720-723
-
-
Bohn, L.M.1
-
6
-
-
0011276168
-
Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance
-
Sharma S.K., et al. Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance. Proc. Natl. Acad. Sci. U. S. A. 72:1975;3092-3096.
-
(1975)
Proc. Natl. Acad. Sci. U. S. A.
, vol.72
, pp. 3092-3096
-
-
Sharma, S.K.1
-
7
-
-
0016749410
-
Morphine abstinence is associated with increased brain cyclic AMP
-
Collier H.O., Francis D.L. Morphine abstinence is associated with increased brain cyclic AMP. Nature. 255:1975;159-162.
-
(1975)
Nature
, vol.255
, pp. 159-162
-
-
Collier, H.O.1
Francis, D.L.2
-
8
-
-
0018133542
-
Tolerance of locus coeruleus neurons to morphine and suppression of withdrawal response by clonidine
-
Aghajanian G.K. Tolerance of locus coeruleus neurons to morphine and suppression of withdrawal response by clonidine. Nature. 276:1978;186-188.
-
(1978)
Nature
, vol.276
, pp. 186-188
-
-
Aghajanian, G.K.1
-
9
-
-
0025867185
-
Pacemaker activity of locus coeruleus neurons: Whole-cell recordings in brain slices show dependence on cAMP and protein kinase a
-
Alreja M., Aghajanian G.K. Pacemaker activity of locus coeruleus neurons: whole-cell recordings in brain slices show dependence on cAMP and protein kinase A. Brain Res. 556:1991;339-343.
-
(1991)
Brain Res.
, vol.556
, pp. 339-343
-
-
Alreja, M.1
Aghajanian, G.K.2
-
10
-
-
0023868861
-
Chronic morphine treatment increases cyclic AMP-dependent protein kinase activity in the rat locus coeruleus
-
Nestler E.J., Tallman J.F. Chronic morphine treatment increases cyclic AMP-dependent protein kinase activity in the rat locus coeruleus. Mol. Pharmacol. 33:1988;127-132.
-
(1988)
Mol. Pharmacol.
, vol.33
, pp. 127-132
-
-
Nestler, E.J.1
Tallman, J.F.2
-
11
-
-
0023723042
-
Acute and chronic opiate regulation of adenylate cyclase in brain: Specific effects in locus coeruleus
-
Duman R.S., et al. Acute and chronic opiate regulation of adenylate cyclase in brain: Specific effects in locus coeruleus. J. Pharmacol. Exp. Ther. 246:1988;1033-1039.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.246
, pp. 1033-1039
-
-
Duman, R.S.1
-
12
-
-
0024849486
-
Identification of morphine- and cyclic AMP-regulated phosphoproteins (MARPPs) in the locus coeruleus and other regions of rat brain: Regulation by acute and chronic morphine
-
Guitart X., Nestler E.J. Identification of morphine- and cyclic AMP-regulated phosphoproteins (MARPPs) in the locus coeruleus and other regions of rat brain: regulation by acute and chronic morphine. J. Neurosci. 9:1989;4371-4387.
-
(1989)
J. Neurosci.
, vol.9
, pp. 4371-4387
-
-
Guitart, X.1
Nestler, E.J.2
-
13
-
-
0028169076
-
Chronic morphine administration causes region-specific increase of brain type VIII adenylyl cyclase mRNA
-
Matsuoka I., et al. Chronic morphine administration causes region-specific increase of brain type VIII adenylyl cyclase mRNA. Eur. J. Pharmacol. 268:1994;215-221.
-
(1994)
Eur. J. Pharmacol.
, vol.268
, pp. 215-221
-
-
Matsuoka, I.1
-
14
-
-
0030803695
-
CREB (cAMP response element-binding protein) in the locus coeruleus: Biochemical, physiological, and behavioral evidence for a role in opiate dependence
-
Lane-Ladd S.B., et al. CREB (cAMP response element-binding protein) in the locus coeruleus: Biochemical, physiological, and behavioral evidence for a role in opiate dependence. J. Neurosci. 17:1997;7890-7901.
-
(1997)
J. Neurosci.
, vol.17
, pp. 7890-7901
-
-
Lane-Ladd, S.B.1
-
15
-
-
0023687711
-
Clonidine infusions into the locus coeruleus attenuate behavioral and neurochemical changes associated with naloxone-precipitated withdrawal
-
Taylor J.R., et al. Clonidine infusions into the locus coeruleus attenuate behavioral and neurochemical changes associated with naloxone-precipitated withdrawal. Psychopharmacology (Berl.). 96:1988;121-134.
-
(1988)
Psychopharmacology (Berl.)
, vol.96
, pp. 121-134
-
-
Taylor, J.R.1
-
16
-
-
0026597790
-
Neural substrates of opiate withdrawal
-
Koob G.F., et al. Neural substrates of opiate withdrawal. Trends Neurosci. 15:1992;186-191.
-
(1992)
Trends Neurosci.
, vol.15
, pp. 186-191
-
-
Koob, G.F.1
-
17
-
-
0027413556
-
Destruction of the locus coeruleus decreases physical signs of opiate withdrawal
-
Maldonado R., Koob G.F. Destruction of the locus coeruleus decreases physical signs of opiate withdrawal. Brain Res. 605:1993;128-138.
-
(1993)
Brain Res.
, vol.605
, pp. 128-138
-
-
Maldonado, R.1
Koob, G.F.2
-
18
-
-
0034719355
-
Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion
-
Delfs J.M., et al. Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion. Nature. 403:2000;430-434.
-
(2000)
Nature
, vol.403
, pp. 430-434
-
-
Delfs, J.M.1
-
19
-
-
0025457883
-
Opiate withdrawal and the rat locus coeruleus: Behavioral, electrophysiological, and biochemical correlates
-
Rasmussen K., et al. Opiate withdrawal and the rat locus coeruleus: Behavioral, electrophysiological, and biochemical correlates. J. Neurosci. 10:1990;2308-2317.
-
(1990)
J. Neurosci.
, vol.10
, pp. 2308-2317
-
-
Rasmussen, K.1
-
20
-
-
0026544355
-
Elevated basal firing rates and enhanced responses to 8-Br-cAMP in locus coeruleus neurons in brain slices from opiate-dependent rats
-
Kogan J.H., et al. Elevated basal firing rates and enhanced responses to 8-Br-cAMP in locus coeruleus neurons in brain slices from opiate-dependent rats. Eur. J. Pharmacol. 211:1992;47-53.
-
(1992)
Eur. J. Pharmacol.
, vol.211
, pp. 47-53
-
-
Kogan, J.H.1
-
21
-
-
0028829387
-
Protein kinases in the locus coeruleus and periaqueductal gray matter are involved in the expression of opiate withdrawal
-
Maldonado R., et al. Protein kinases in the locus coeruleus and periaqueductal gray matter are involved in the expression of opiate withdrawal. Naunyn Schmiedebergs Arch. Pharmacol. 352:1995;565-575.
-
(1995)
Naunyn Schmiedebergs Arch. Pharmacol
, vol.352
, pp. 565-575
-
-
Maldonado, R.1
-
22
-
-
0030728473
-
Opposite modulation of opiate withdrawal behaviors upon microinfusion of a protein kinase a inhibitor versus activator into the locus coeruleus or periaqueductal gray
-
Punch L., et al. Opposite modulation of opiate withdrawal behaviors upon microinfusion of a protein kinase A inhibitor versus activator into the locus coeruleus or periaqueductal gray. J. Neurosci. 17:1997;8520-8527.
-
(1997)
J. Neurosci.
, vol.17
, pp. 8520-8527
-
-
Punch, L.1
-
23
-
-
0030921184
-
Local opiate withdrawal in locus coeruleus in vivo
-
Aston-Jones G., et al. Local opiate withdrawal in locus coeruleus in vivo. Brain Res. 765:1997;331-336.
-
(1997)
Brain Res.
, vol.765
, pp. 331-336
-
-
Aston-Jones, G.1
-
24
-
-
0030887289
-
Where is the locus in opioid withdrawal?
-
Christie M.J., et al. Where is the locus in opioid withdrawal? Trends Pharmacol. Sci. 18:1997;134-140.
-
(1997)
Trends Pharmacol. Sci.
, vol.18
, pp. 134-140
-
-
Christie, M.J.1
-
25
-
-
0018189433
-
Clonidine blocks acute opiate withdrawal symptoms
-
Gold M.S., et al. Clonidine blocks acute opiate withdrawal symptoms. Lancet. 2:1978;599-602.
-
(1978)
Lancet
, vol.2
, pp. 599-602
-
-
Gold, M.S.1
-
26
-
-
0025760593
-
A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function
-
Terwilliger R.Z., et al. A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function. Brain Res. 548:1991;100-110.
-
(1991)
Brain Res.
, vol.548
, pp. 100-110
-
-
Terwilliger, R.Z.1
-
27
-
-
0031012148
-
Increased probability of GABA release during withdrawal from morphine
-
Bonci A., Williams J.T. Increased probability of GABA release during withdrawal from morphine. J. Neurosci. 17:1997;796-803.
-
(1997)
J. Neurosci.
, vol.17
, pp. 796-803
-
-
Bonci, A.1
Williams, J.T.2
-
28
-
-
0030766528
-
Molecular and cellular basis of addiction
-
Nestler E.J., Aghajanian G.K. Molecular and cellular basis of addiction. Science. 278:1997;58-63.
-
(1997)
Science
, vol.278
, pp. 58-63
-
-
Nestler, E.J.1
Aghajanian, G.K.2
-
29
-
-
0037100365
-
Stimulation of protein kinase a activity in the rat amygdala enhances reward-related learning
-
Jentsch J.D., et al. Stimulation of protein kinase A activity in the rat amygdala enhances reward-related learning. Biol. Psychiatry. 52:2002;111-118.
-
(2002)
Biol. Psychiatry
, vol.52
, pp. 111-118
-
-
Jentsch, J.D.1
-
30
-
-
0035260641
-
Molecular basis of neural plasticity underlying addiction
-
Nestler E.J. Molecular basis of neural plasticity underlying addiction. Nat. Rev. Neurosci. 2:2001;119-128.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 119-128
-
-
Nestler, E.J.1
-
31
-
-
0026541104
-
Regulation of cAMP response element-binding protein phosphorylation by acute and chronic morphine in the rat locus coeruleus
-
Guitart X., et al. Regulation of cAMP response element-binding protein phosphorylation by acute and chronic morphine in the rat locus coeruleus. J. Neurochem. 58:1992;1168-1171.
-
(1992)
J. Neurochem.
, vol.58
, pp. 1168-1171
-
-
Guitart, X.1
-
32
-
-
0027997104
-
Regulation of expression of cAMP response element binding protein in the locus coeruleus in vivo and in a locus coeruleus-like (CATH.a) cell line in vitro
-
Widnell K.L., et al. Regulation of expression of cAMP response element binding protein in the locus coeruleus in vivo and in a locus coeruleus-like (CATH.a) cell line in vitro. Proc. Natl. Acad. Sci. U. S. A. 91:1994;10947-10951.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 10947-10951
-
-
Widnell, K.L.1
-
33
-
-
0036581180
-
Regional and cellular mapping of cAMP response element-mediated transcription during naltrexone-precipitated morphine withdrawal
-
Shaw-Lutchman T.Z., et al. Regional and cellular mapping of cAMP response element-mediated transcription during naltrexone-precipitated morphine withdrawal. J. Neurosci. 22:2002;3663-3672.
-
(2002)
J. Neurosci.
, vol.22
, pp. 3663-3672
-
-
Shaw-Lutchman, T.Z.1
-
34
-
-
1942498723
-
Direct evidence for a role of CREB in the locus coeruleus in opiate dependence
-
Han M.-H., et al. Direct evidence for a role of CREB in the locus coeruleus in opiate dependence. Soc. Neurosci. Abstr. 29:2003;644.6.
-
(2003)
Soc. Neurosci. Abstr.
, vol.29
, pp. 6446
-
-
Han, M.-H.1
-
35
-
-
0029764770
-
Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB
-
Maldonado R., et al. Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB. Science. 273:1996;657-659.
-
(1996)
Science
, vol.273
, pp. 657-659
-
-
Maldonado, R.1
-
36
-
-
0003401166
-
-
American Psychiatric Press
-
American Psychiatric Association. Diagnostic and Statistical Manual. 2000;American Psychiatric Press.
-
(2000)
Diagnostic and Statistical Manual
-
-
-
37
-
-
0020052814
-
Reinforcing effects of morphine in the nucleus accumbens
-
Olds M.E. Reinforcing effects of morphine in the nucleus accumbens. Brain Res. 237:1982;429-440.
-
(1982)
Brain Res.
, vol.237
, pp. 429-440
-
-
Olds, M.E.1
-
38
-
-
0025855256
-
The dopamine hypothesis of the reinforcing properties of cocaine
-
Kuhar M.J., et al. The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci. 14:1991;299-302.
-
(1991)
Trends Neurosci.
, vol.14
, pp. 299-302
-
-
Kuhar, M.J.1
-
39
-
-
0032169803
-
Neuroscience of addiction
-
Koob G.F., et al. Neuroscience of addiction. Neuron. 21:1998;467-476.
-
(1998)
Neuron
, vol.21
, pp. 467-476
-
-
Koob, G.F.1
-
40
-
-
0032104560
-
Drug-activation of brain reward pathways
-
Wise R.A. Drug-activation of brain reward pathways. Drug Alcohol Depend. 51:1998;13-22.
-
(1998)
Drug Alcohol Depend.
, vol.51
, pp. 13-22
-
-
Wise, R.A.1
-
41
-
-
0343933624
-
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats
-
Di Chiara G., Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl. Acad. Sci. U. S. A. 85:1988;5274-5278.
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 5274-5278
-
-
Di Chiara, G.1
Imperato, A.2
-
42
-
-
0036584948
-
Psychomotor stimulant addiction: A neural systems perspective
-
Everitt B.J., Wolf M.E. Psychomotor stimulant addiction: a neural systems perspective. J. Neurosci. 22:2002;3312-3320.
-
(2002)
J. Neurosci.
, vol.22
, pp. 3312-3320
-
-
Everitt, B.J.1
Wolf, M.E.2
-
43
-
-
0036582977
-
The neuroscience of natural rewards: Relevance to addictive drugs
-
Kelley A.E., Berridge K.C. The neuroscience of natural rewards: relevance to addictive drugs. J. Neurosci. 22:2002;3306-3311.
-
(2002)
J. Neurosci.
, vol.22
, pp. 3306-3311
-
-
Kelley, A.E.1
Berridge, K.C.2
-
44
-
-
0033714116
-
C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway
-
Sawin E.R., et al. C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway. Neuron. 26:2000;619-631.
-
(2000)
Neuron
, vol.26
, pp. 619-631
-
-
Sawin, E.R.1
-
45
-
-
0032518346
-
Stereotypic behavioral responses to free-base cocaine and the development of behavioral sensitization in Drosophila
-
McClung C., Hirsh J. Stereotypic behavioral responses to free-base cocaine and the development of behavioral sensitization in Drosophila. Curr. Biol. 8:1998;109-112.
-
(1998)
Curr. Biol.
, vol.8
, pp. 109-112
-
-
McClung, C.1
Hirsh, J.2
-
46
-
-
0037187646
-
Neurobiology of depression
-
Nestler E.J., et al. Neurobiology of depression. Neuron. 34:2002;13-25.
-
(2002)
Neuron
, vol.34
, pp. 13-25
-
-
Nestler, E.J.1
-
47
-
-
0033850835
-
Stress-induced relapse to heroin and cocaine seeking in rats: A review
-
Shaham Y., et al. Stress-induced relapse to heroin and cocaine seeking in rats: a review. Brain Res. Rev. 33:2000;13-33.
-
(2000)
Brain Res. Rev.
, vol.33
, pp. 13-33
-
-
Shaham, Y.1
-
48
-
-
0027237106
-
Animal models of drug craving
-
Markou A., et al. Animal models of drug craving. Psychopharmacology (Berl.). 112:1993;163-182.
-
(1993)
Psychopharmacology (Berl.)
, vol.112
, pp. 163-182
-
-
Markou, A.1
-
49
-
-
0029870443
-
2-like dopamine receptor agonists
-
2-like dopamine receptor agonists. Science. 271:1996;1586-1589.
-
(1996)
Science
, vol.271
, pp. 1586-1589
-
-
Self, D.W.1
-
50
-
-
0037743546
-
Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse
-
Baker D.A., et al. Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse. Nat. Neurosci. 6:2003;743-774.
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 743-774
-
-
Baker, D.A.1
-
51
-
-
0030042150
-
Effects of lesions to amygdala, ventral subiculum, medial prefrontal cortex, and nucleus accumbens on the reaction to novelty: Implication for limbic-striatal interactions
-
Burns L.H., et al. Effects of lesions to amygdala, ventral subiculum, medial prefrontal cortex, and nucleus accumbens on the reaction to novelty: implication for limbic-striatal interactions. Behav. Neurosci. 110:1996;60-73.
-
(1996)
Behav. Neurosci.
, vol.110
, pp. 60-73
-
-
Burns, L.H.1
-
52
-
-
0032104731
-
Neuroadaptations involved in amphetamine and cocaine addiction
-
White F.J., Kalivas P.W. Neuroadaptations involved in amphetamine and cocaine addiction. Drug Alcohol Depend. 51:1998;141-153.
-
(1998)
Drug Alcohol Depend.
, vol.51
, pp. 141-153
-
-
White, F.J.1
Kalivas, P.W.2
-
53
-
-
0032936543
-
Neural systems for behavioral activation and reward
-
Kalivas P.W., Nakamura M. Neural systems for behavioral activation and reward. Curr. Opin. Neurobiol. 9:1999;223-227.
-
(1999)
Curr. Opin. Neurobiol.
, vol.9
, pp. 223-227
-
-
Kalivas, P.W.1
Nakamura, M.2
-
54
-
-
0034016263
-
Addiction, a disease of compulsion and drive: Involvement of the orbitofrontal cortex
-
Volkow N.D., Fowler J.S. Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex. Cereb. Cortex. 10:2000;318-325.
-
(2000)
Cereb. Cortex
, vol.10
, pp. 318-325
-
-
Volkow, N.D.1
Fowler, J.S.2
-
55
-
-
0029563776
-
Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system
-
Ortiz J., et al. Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system. Synapse. 21:1995;289-298.
-
(1995)
Synapse
, vol.21
, pp. 289-298
-
-
Ortiz, J.1
-
56
-
-
0037399610
-
Regulation of CRE-mediated transcription in mouse brain by amphetamine
-
Shaw-Lutchman T.Z., et al. Regulation of CRE-mediated transcription in mouse brain by amphetamine. Synapse. 48:2003;10-17.
-
(2003)
Synapse
, vol.48
, pp. 10-17
-
-
Shaw-Lutchman, T.Z.1
-
57
-
-
0028931471
-
Neuronal adaptation to amphetamine and dopamine: Molecular mechanisms of prodynorphin gene regulation in rat striatum
-
Cole R.L., et al. Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum. Neuron. 14:1995;813-823.
-
(1995)
Neuron
, vol.14
, pp. 813-823
-
-
Cole, R.L.1
-
58
-
-
0036130919
-
Ethanol stimulates cAMP-responsive element (CRE)-mediated transcription via CRE-binding protein and cAMP-dependent protein kinase
-
Asher O., et al. Ethanol stimulates cAMP-responsive element (CRE)-mediated transcription via CRE-binding protein and cAMP-dependent protein kinase. J. Pharmacol. Exp. Ther. 301:2002;66-70.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.301
, pp. 66-70
-
-
Asher, O.1
-
59
-
-
20644461933
-
Regulation of cocaine reward by CREB
-
Carlezon W.A. Jr, et al. Regulation of cocaine reward by CREB. Science. 282:1998;2272-2275.
-
(1998)
Science
, vol.282
, pp. 2272-2275
-
-
Carlezon Jr., W.A.1
-
60
-
-
0032031594
-
Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior
-
Self D.W., et al. Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior. J. Neurosci. 18:1998;1848-1859.
-
(1998)
J. Neurosci.
, vol.18
, pp. 1848-1859
-
-
Self, D.W.1
-
61
-
-
0035884949
-
Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in the nucleus accumbens
-
Pliakas A.M., et al. Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in the nucleus accumbens. J. Neurosci. 21:2001;7397-7403.
-
(2001)
J. Neurosci.
, vol.21
, pp. 7397-7403
-
-
Pliakas, A.M.1
-
62
-
-
0035576019
-
Different requirements for cAMP response element binding protein in positive and negative reinforcing properties of drugs of abuse
-
Walters C.L., Blendy J.A. Different requirements for cAMP response element binding protein in positive and negative reinforcing properties of drugs of abuse. J. Neurosci. 21:2001;9438-9444.
-
(2001)
J. Neurosci.
, vol.21
, pp. 9438-9444
-
-
Walters, C.L.1
Blendy, J.A.2
-
63
-
-
0037143736
-
CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli
-
Barrot M., et al. CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc. Natl. Acad. Sci. U. S. A. 99:2002;11435-11440.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 11435-11440
-
-
Barrot, M.1
-
64
-
-
0037115028
-
Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect
-
Newton S.S., et al. Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect. J. Neurosci. 22:2002;10883-10890.
-
(2002)
J. Neurosci.
, vol.22
, pp. 10883-10890
-
-
Newton, S.S.1
-
65
-
-
0242384719
-
Regulation of gene expression and cocaine reward by CREB and ΔfosB
-
McClung C.A., Nestler E.J. Regulation of gene expression and cocaine reward by CREB and ΔFosB. Nat. Neurosci. 11:2003;1208-1215.
-
(2003)
Nat. Neurosci.
, vol.11
, pp. 1208-1215
-
-
McClung, C.A.1
Nestler, E.J.2
-
66
-
-
0030740849
-
Sensitization to the behavioral effects of cocaine: Modulation by dynorphin and kappa-opioid receptor agonists
-
Shippenberg T.S., Rea W. Sensitization to the behavioral effects of cocaine: modulation by dynorphin and kappa-opioid receptor agonists. Pharmacol. Biochem. Behav. 57:1997;449-455.
-
(1997)
Pharmacol. Biochem. Behav.
, vol.57
, pp. 449-455
-
-
Shippenberg, T.S.1
Rea, W.2
-
67
-
-
0034883666
-
GR89,696: A potent kappa-opioid agonist with subtype selectivity in rhesus monkeys
-
Butelman E.R., et al. GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus monkeys. J. Pharmacol. Exp. Ther. 298:2001;1049-1059.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, pp. 1049-1059
-
-
Butelman, E.R.1
-
68
-
-
0026645205
-
Molecular mechanisms of drug addiction
-
Nestler E.J. Molecular mechanisms of drug addiction. J. Neurosci. 12:1992;2439-2450.
-
(1992)
J. Neurosci.
, vol.12
, pp. 2439-2450
-
-
Nestler, E.J.1
-
69
-
-
0026552172
-
Correlation between behavioral sensitization to cocaine and G protein ADP-ribosylation in the ventral tegmental area
-
Striplin C.D., Kalivas P.W. Correlation between behavioral sensitization to cocaine and G protein ADP-ribosylation in the ventral tegmental area. Brain Res. 579:1992;181-186.
-
(1992)
Brain Res.
, vol.579
, pp. 181-186
-
-
Striplin, C.D.1
Kalivas, P.W.2
-
70
-
-
0027092595
-
Responses of limbic and extrapyramidal neurotensin systems to stimulants of abuse. Involvement of dopaminergic mechanisms
-
Hanson G.R., et al. Responses of limbic and extrapyramidal neurotensin systems to stimulants of abuse. Involvement of dopaminergic mechanisms. Ann. New York Acad. Sci. 668:1992;165-172.
-
(1992)
Ann. New York Acad. Sci.
, vol.668
, pp. 165-172
-
-
Hanson, G.R.1
-
71
-
-
0030044516
-
Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: Common adaptations among cross-sensitizing agents
-
Fitzgerald L.W., et al. Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents. J. Neurosci. 16:1996;274-282.
-
(1996)
J. Neurosci.
, vol.16
, pp. 274-282
-
-
Fitzgerald, L.W.1
-
72
-
-
0036890466
-
Elevated levels of GluR1 in the midbrain: A trigger for sensitization to drugs of abuse?
-
Carlezon W.A. Jr, Nestler E.J. Elevated levels of GluR1 in the midbrain: a trigger for sensitization to drugs of abuse? Trends Neurosci. 25:2002;610-615.
-
(2002)
Trends Neurosci.
, vol.25
, pp. 610-615
-
-
Carlezon Jr., W.A.1
Nestler, E.J.2
-
73
-
-
0025155482
-
Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum
-
Graybiel A.M., et al. Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum. Proc. Natl. Acad. Sci. U. S. A. 87:1990;6912-6916.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 6912-6916
-
-
Graybiel, A.M.1
-
74
-
-
0025974077
-
Cocaine induces striatal c-fos-immunoreactive proteins via dopaminergic D1 receptors
-
Young S.T., et al. Cocaine induces striatal c-fos-immunoreactive proteins via dopaminergic D1 receptors. Proc. Natl. Acad. Sci. U. S. A. 88:1991;1291-1295.
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 1291-1295
-
-
Young, S.T.1
-
75
-
-
0026687425
-
Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine
-
Hope B., et al. Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine. Proc. Natl. Acad. Sci. U. S. A. 89:1992;5764-5768.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 5764-5768
-
-
Hope, B.1
-
76
-
-
0027992668
-
Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments
-
Hope B.T., et al. Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments. Neuron. 13:1994;1235-1244.
-
(1994)
Neuron
, vol.13
, pp. 1235-1244
-
-
Hope, B.T.1
-
77
-
-
0028971647
-
Regulation of ΔfosB and FosB-like proteins by electroconvulsive seizure and cocaine treatments
-
Chen J.S., et al. Regulation of ΔFosB and FosB-like proteins by electroconvulsive seizure and cocaine treatments. Mol. Pharmacol. 48:1995;880-889.
-
(1995)
Mol. Pharmacol.
, vol.48
, pp. 880-889
-
-
Chen, J.S.1
-
78
-
-
0030986666
-
Chronic Fos-related antigens: Stable variants of ΔfosB induced in brain by chronic treatments
-
Chen J., et al. Chronic Fos-related antigens: stable variants of ΔFosB induced in brain by chronic treatments. J. Neurosci. 17:1997;4933-4941.
-
(1997)
J. Neurosci.
, vol.17
, pp. 4933-4941
-
-
Chen, J.1
-
79
-
-
0030885427
-
FosB mutant mice: Loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects
-
Hiroi N., et al. FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects. Proc. Natl. Acad. Sci. U. S. A. 94:1997;10397-10402.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 10397-10402
-
-
Hiroi, N.1
-
80
-
-
0029552395
-
Pharmacological studies of the regulation of chronic Fos-related antigen induction by cocaine in the striatum and nucleus accumbens
-
Nye H., et al. Pharmacological studies of the regulation of chronic Fos-related antigen induction by cocaine in the striatum and nucleus accumbens. J. Pharmacol. Exp. Ther. 275:1995;1671-1680.
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.275
, pp. 1671-1680
-
-
Nye, H.1
-
81
-
-
0030200394
-
Network-level changes in expression of inducible Fos-Jun proteins in the striatum during chronic cocaine treatment and withdrawal
-
Moratalla R., et al. Network-level changes in expression of inducible Fos-Jun proteins in the striatum during chronic cocaine treatment and withdrawal. Neuron. 17:1996;147-156.
-
(1996)
Neuron
, vol.17
, pp. 147-156
-
-
Moratalla, R.1
-
82
-
-
0029960788
-
Induction of chronic Fos-related antigens in rat brain by chronic morphine administration
-
Nye H.E., Nestler E.J. Induction of chronic Fos-related antigens in rat brain by chronic morphine administration. Mol. Pharmacol. 49:1996;636-645.
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 636-645
-
-
Nye, H.E.1
Nestler, E.J.2
-
83
-
-
0031016618
-
Common neural substrates for the addictive properties of nicotine and cocaine
-
Pich E.M., et al. Common neural substrates for the addictive properties of nicotine and cocaine. Science. 275:1997;83-86.
-
(1997)
Science
, vol.275
, pp. 83-86
-
-
Pich, E.M.1
-
84
-
-
0037107158
-
ΔfosB regulates wheel running
-
Werme M., et al. ΔFosB regulates wheel running. J. Neurosci. 22:2002;8133-8138.
-
(2002)
J. Neurosci.
, vol.22
, pp. 8133-8138
-
-
Werme, M.1
-
85
-
-
0035949351
-
ΔfosB: A molecular switch for addiction
-
Nestler E.J., et al. ΔFosB: a molecular switch for addiction. Proc. Natl. Acad. Sci. U. S. A. 98:2001;11042-11046.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 11042-11046
-
-
Nestler, E.J.1
-
86
-
-
0033575937
-
Expression of the transcription factor ΔfosB in the brain controls sensitivity to cocaine
-
Kelz M.B., et al. Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine. Nature. 401:1999;272-276.
-
(1999)
Nature
, vol.401
, pp. 272-276
-
-
Kelz, M.B.1
-
87
-
-
0347928858
-
Inducible, brain region specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine
-
Peakman M.C., et al. Inducible, brain region specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine. Brain Res. 970:2003;73-86.
-
(2003)
Brain Res.
, vol.970
, pp. 73-86
-
-
Peakman, M.C.1
-
88
-
-
0037444572
-
Striatal cell type-specific overexpression of delta-FosB enhances incentive for cocaine
-
Colby C.R., et al. Striatal cell type-specific overexpression of delta-FosB enhances incentive for cocaine. J. Neurosci. 23:2003;2488-2493.
-
(2003)
J. Neurosci.
, vol.23
, pp. 2488-2493
-
-
Colby, C.R.1
-
89
-
-
1942434489
-
ΔfosB in the nucleus accumbens modulates morphine reward, tolerance, and dependence
-
Zachariou V., et al. ΔFosB in the nucleus accumbens modulates morphine reward, tolerance, and dependence. Soc. Neurosci. Abstr. 29:2003;112.16.
-
(2003)
Soc. Neurosci. Abstr.
, vol.29
, pp. 11216
-
-
Zachariou, V.1
-
90
-
-
1942530564
-
Enhanced incentive motivation in ΔfosB overexpressing mice
-
Olausson P., et al. Enhanced incentive motivation in ΔFosB overexpressing mice. Soc. Neurosci. Abstr. 28:2002;502-514.
-
(2002)
Soc. Neurosci. Abstr.
, vol.28
, pp. 502-514
-
-
Olausson, P.1
-
91
-
-
0029784475
-
Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons
-
Sklair-Tavron L., et al. Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons. Proc. Natl. Acad. Sci. U. S. A. 93:1996;11202-11207.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 11202-11207
-
-
Sklair-Tavron, L.1
-
92
-
-
0033566311
-
Morphine alters the structure of neurons in the nucleus accumbens and neocortex of rats
-
Robinson T.E., Kolb B. Morphine alters the structure of neurons in the nucleus accumbens and neocortex of rats. Synapse. 33:1999;160-162.
-
(1999)
Synapse
, vol.33
, pp. 160-162
-
-
Robinson, T.E.1
Kolb, B.2
-
93
-
-
0030732153
-
Persistent structural modifications in nucleus accumbens and prefrontal cortex neurons produced by previous experience with amphetamine
-
Robinson T.E., Kolb B. Persistent structural modifications in nucleus accumbens and prefrontal cortex neurons produced by previous experience with amphetamine. J. Neurosci. 17:1997;8491-8497.
-
(1997)
J. Neurosci.
, vol.17
, pp. 8491-8497
-
-
Robinson, T.E.1
Kolb, B.2
-
94
-
-
0035868898
-
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5
-
Bibb J.A., et al. Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5. Nature. 410:2001;376-380.
-
(2001)
Nature
, vol.410
, pp. 376-380
-
-
Bibb, J.A.1
-
95
-
-
0345894315
-
Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5
-
Norrholm S.D., et al. Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5. Neuroscience. 116:2003;19-22.
-
(2003)
Neuroscience
, vol.116
, pp. 19-22
-
-
Norrholm, S.D.1
-
96
-
-
0033695676
-
Addiction, dopamine, and the molecular mechanisms of memory
-
Berke J.D., Hyman S.E. Addiction, dopamine, and the molecular mechanisms of memory. Neuron. 25:2000;515-532.
-
(2000)
Neuron
, vol.25
, pp. 515-532
-
-
Berke, J.D.1
Hyman, S.E.2
-
97
-
-
0035489031
-
Addiction and the brain: The neurobiology of compulsion and its persistence
-
Hyman S.E., Malenka R.C. Addiction and the brain: the neurobiology of compulsion and its persistence. Nat. Rev. Neurosci. 2:2001;695-703.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 695-703
-
-
Hyman, S.E.1
Malenka, R.C.2
-
98
-
-
0036881834
-
Common molecular and cellular substrates of addiction and memory
-
Nestler E.J. Common molecular and cellular substrates of addiction and memory. Neurobiol. Learn. Mem. 78:2002;637-647.
-
(2002)
Neurobiol. Learn. Mem.
, vol.78
, pp. 637-647
-
-
Nestler, E.J.1
-
99
-
-
0034254987
-
Amphetamine blocks long-term synaptic depression in the ventral tegmental area
-
Jones S., et al. Amphetamine blocks long-term synaptic depression in the ventral tegmental area. J. Neurosci. 20:2000;5575-5580.
-
(2000)
J. Neurosci.
, vol.20
, pp. 5575-5580
-
-
Jones, S.1
-
100
-
-
0035204242
-
Long-term depression in the nucleus accumbens: A neural correlate of behavioral sensitization to cocaine
-
Thomas M.J., et al. Long-term depression in the nucleus accumbens: a neural correlate of behavioral sensitization to cocaine. Nat. Neurosci. 4:2001;1217-1223.
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 1217-1223
-
-
Thomas, M.J.1
-
101
-
-
0037456565
-
Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons
-
Saal D., et al. Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons. Neuron. 37:2003;577-582.
-
(2003)
Neuron
, vol.37
, pp. 577-582
-
-
Saal, D.1
|