Enhanced CREB phosphorylation and changes in c-Fos and FRA expression in striatum accompany amphetamine sensitization

Brain Research

Volumn 749, Issue 1, 1997, Pages 120-126

  Turgeon, Sarah M ^a,b   Pollack, Alexia E ^a,c   Fink, J Stephen ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b AMHERST COLLEGE   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

Amphetamine; c Fos; CREB; Fos related antigen; Psychostimulant; Sensitization

Indexed keywords

AMPHETAMINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; CORPUS STRIATUM; IMMUNOBLOTTING; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SENSITIZATION;

ACTIVATING TRANSCRIPTION FACTOR 2; AMPHETAMINE; ANIMALS; ANTIGENS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; CENTRAL NERVOUS SYSTEM STIMULANTS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; INFANT; MALE; NEOSTRIATUM; OLIGONUCLEOTIDES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS;

EID: 0031037430     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01316-9     Document Type: Article

References (45)

1. Bonni, A., Ginty, D.D., Dudek, H. and Greenberg, M.E., Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals, Mol. Cell. Neurosci., 6 (1995) 168-183.
2. Bronstein, D.M., Ye, H., Pennypacker, K.R., Hudson, P.M. and Hong, J.-S., Role of a 35 kDa fos-related antigen (FRA) in the long-term induction of striatal dynorphin expression in the 6-hydroxydopamine lesioned rat, Mol. Brain Res., 23 (1994) 191-203.
3. Cole, R.L., Konradi, C., Douglass, J. and Hyman, S.E., Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum, Neuron, 14 (1995) 813-823.
4. Couceyo, P., Pollock, K.M., Drews, K. and Douglass, J., Cocaine differentially regulates activator protein-1 mRNA levels and DNA binding complexes in the rat striatum and cerebellum, Mol. Pharmacol, 46 (1994) 667-676.
5. Daunais, J.B. and McGinty, J.F, Acute and chronic cocaine administration differentially alters striatal opiod and nuclear transcription factor mRNAs, Synapse, 18 (1994) 35-45.
6. Daunais, J.B. and McGinty, J.F. Cocaine binges differentially alter striatal preprodynorphin and Zif /268 mRNAs, Mol. Brain Res., 29 (1995)201-210.
7. Ennulat, D.J., Babb, S.M. and Cohen, B.M., Persistent reduction of immediate early gene mRNA in rat forebrain following single or multiple doses of cocaine, Mol. Brain Res., 26 (1994) 106-112.
8. Gonzalez, G.A. and Montminy, M.R., Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133, Cell, 59 (1989) 675-680.
9. Hamamura, T., Akiyama, K., Akimoto, K., Kashihara, K., Okuma, K., Ujike, H. and Otsuki, S., Coadministration of a selective Dl or D2 dopamine agonist with methamphetamine prevents methamphetamine-induced behavioral sensitization and neurochemical change, studied by in vivo intracerebral dialysis, Brain Res., 546 (1991)40-46.
10. Heidbreder, C., Goldberg, S. and Shippenberg, T.S., The kappa opiod receptor agonist U-69593 attenuates cocaine-induced behavioral sensitization in rats, Brain Res., 616 (1993) 333-338.
11. Henry, D.J. and White, F.J., The persistence of behavioral sensitization to cocaine parallels enhanced inhibition of nucleus accumbens neurons, J. Neurosci., 15 (1995) 6287-6299.
12. Hope, B., Kosofsky, B., Hyman, S.E. and Nestler, E.J., Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine, Proc Natl. Acad. Sci. USA, 89 (1992) 5764-5768.
13. Hope, B., Nye, H., Ketz, M., Self, D., Iadarola, M., Nakabeppu, Y., Duman, R.S. and Nestler, E.J., Induction of a long-lasting AP-1 complex composed of altered fos-like proteins in brain by chronic cocaine and other chronic treatments, Neuron, 13(1994) 1235-1244.
14. Horger, B.A., Giles, M.K. and Schenk, S., Preexposure to amphetamine and nicotine predisposes rats to self-administer a low dose of cocaine, Psychopharmacology, 107 (1992) 271-276.
15. Horger, B.A., Shelton, K. and Schenk, S., Preexposure sensitizes rats to the rewarding effects of cocaine, Pharm. Biochem. Behav., 37 (1990) 707-711.
16. Hurd, Y.L., Lindefors, N., Brodin, E., Brene, S., Persson, H., Ungerstedt, U. and Hokfelt, T., Amphetamine regulation of mesolimbic dopamine-cholecystokinin neurotransmission, Brain Res., 578 (1992) 317-326.
17. Hurd, Y.L., Weiss, F., Anden, N.-E., Koob, G.F. and Ungerstedt, U., Cocaine reinforcement and extracellular dopamine overflow: an in vivo mircrodialysis study, Brain Res., 498 (1989) 199-203.
18. Jaber, M., Cador, M., Dumartin, B., Normand, E., Stimus, L. and Bloch, B., Acute and chronic amphetamine treatments differentially regulate neuropeptide messenger RNA levels and Fos immuno-reactivity in rat striatal neurons, Neuroscience, 65 (1995) 1041-1050.
19. Kalivas, P.W. and Duffy, P., Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens, Synapse, 5 (1990) 48-58.
20. Karler, R., Calder, L.D. and Turkanis, S.A., DNQX blockade of amphetamine behavioral sensitization, Brain Res., 552 (1991) 295-300.
21. Koob, G.F., Drugs of abuse: anatomy, pharmacology and function of reward pathways, Trends Pharmacol. Sci., 13 (1992) 177-184.
22. Konradi, C., Cole, R.L., Heckers, S. and Hyman, S.E., Amphetamine regulates gene expression in rat striatum via transcription factor CREB, J. Neurosci., 14 (1994) 5623-5634.
23. Miserendino, J.D. and Nestler, E.J., Behavioral sensitization to cocaine: modulation by the cyclic AMP system in the nucleus accumbens, Brain Res., 674 (1995) 299-306.
24. Montminy, M.R., Gonzalez, G.A. and Yamamoto, K.K., Regulation of cAMP-inducible genes by CREB, Trends Neurosci., 13 (1990) 184-188.
25. Mulder, A.M., Wardeh, G., Hogenboom, F. and Frankhuyzen, A.L., κ-and α-opiod receptor agonists differentially inhibit striatal dopamine and acetylcholine release, Nature, 308 (1984) 278-280.
26. Nestler, E.R., Hope, B.T. and Widnell, K.L., Drug addiction: a model for the molecular basis of neural plasticity, Neuron, 11 (1993)995-1006.
27. o in dicrete regions of rat brain, J. Neurochem., 55 (1990) 1079-1082.
28. Nye, H.E., Hope, B.T., Kelz, M.B., Iadarola, M. and Nestler, E.J., Pharmacological studies of the regulation of chronic Fos-related antigen induction by cocaine in the striatum and nucleus accumbens. J. Pharmacol Exp. Ther., 275 (1995) 1671-1680.
29. Ohmori,T., Abekawa, T., Muraki, A. and Koyama, T., Competitive and noncompetitive NMDA antagonists block sensitization to methamphetamine, Pharmacol. Biochem Behav., 48 (1994) 587-591.
30. Persico, A.M., Schindler, C.W., O'Hara, B.F., Brannock, M.T. and Uhl, G., Brain transcription factor expression: effects of acute and chronic amphetamine and injection stress, Mol. Brain Res., 20 (1993)91-100.
31. Piazza, P.V., Deminiere, J.M., LeMoal, M. and Simon, H., Stress-and pharmacologically-induced behavioral sensitization increases vulnerability to acquisition of amphetamine self-administration, Brain Res., 514 (1990) 22-26.
32. Robinson, T.E. and Becker, J., Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis, Brain Res. Rev., 11 (1986) 157-198.
33. Robinson, T.E. and Berridge, K.C., The neural basis of drug craving: an incentive-sensitization theory of addiction, Brain Res. Rev., 18(1993)247-291.
34. Robinson, T.E., Jurson, P.A., Bennett, J.A. and Bentgen, K.M., Persistent sensitization of dopamine neurotransmission in ventral striatum (nucleus accumbens) produced by prior experience with ( + )-amphetamine: a microdialysis study in freely moving rats, Brain Res., 462 (1988) 211-222.
35. Robinson, I.E., Yew, J., Paulson, P.E. and Camp, D.M., The long-term effects of neurotoxic doses of methamphetamine on the extracellular concentration of dopamine measured with microdialysis in striatum, Neurosci. Lett., 110 (1990) 193-198.
36. Rosen, J.B., Chuang, E. and Iadarola, M.J., Differential induction of Fos protein and a Fos-related antigen following acute and repeated cocaine administration, Mol. Brain Res., 25 (1994) 168-172.
37. Sheng, M., McFadden, G. and Greenberg, M.E., Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB, Neuron, 4 (1990) 571-582.
38. Simpson, J.N., Wang, J.Q. and McGinty, J.F., Repeated amphetamine administration induces a prolonged augmentation of phoshorylated cyclase response element-binding protein and Fos-related antigen in rat striatum, Neuroscience, 69 (1995) 441-457.
39. Steiner, H. and Gerfen, C.R., Cocaine-induced c-fos messenger RNA is inversely related to dynorphin expression in striatum, J. Neurosci., 13 (1003) 5066-5081.
40. Striplin, C. and Kalivas, P.W., Robustness of G protein changes in cocaine sensitization shown with immunoblotting, Synapse, 14 (1993) 10-15.
41. Symes, A.J., Lewis, S.E., Corpus, L., Rajan, P., Hyman, S.E. and Fink, J.S., STAT transcription factors participate in regulation of the VIP gene by the CNTF family of cytokines, Mol. Endocrinol., 8 (1994) 1750-1763.
42. Terwilliger, R., Beitner-Johnson, D., Sevarino, K.A., Grain, S.M. and Nestler, E.J., A general role for adaptions in G-proteins and the cylic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function, Brain Res., 548 (1991) 100-110.
43. Wang, J.Q. and McGinty, J.F., Alterations in striatal zif/268, predynorphin and preproenkephalin mRNA expression induced by repeated amphetamine administration in rats. Brain Res., 673 (1995) 262-274.
44. Wolf, M.E., White, F.J. and Hu, X.-T., MK-801 prevents alteration in the mesoaccumbens dopamine system asociated with behavioral sensitization to amphetamine, J. Neurosci., 14 (1994) 1735-1745.
45. Zhang, W.Q., Pennypacker, K.R., Ye, H., Merchenthaler, I.J., Grimes, L., Iadarola, M.J. and Hong J.S., A 35 kDa Fos-related antigen is co-localized with substance P and dynorphin in striatal neurons, Brain Res., 577 (1992) 312-317.