Antidepressant-like effects of κ-opioid receptor antagonists in the forced swim test in rats

Journal of Pharmacology and Experimental Therapeutics

Volumn 305, Issue 1, 2003, Pages 323-330

  Mague, Stephen D ^a   Pliakas, Andrea M ^a   Todtenkopf, Mark S ^a   Tomasiewicz, Hilarie C ^a   Zhang, Yan ^b   Stevens Jr , William C ^b   Jones, Robert M ^b   Portoghese, Philip S ^b   Carlezon Jr , William A ^a,b  

^a MCLEAN HOSPITAL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' ACETAMIDINOETHYLNALTRINDOLE; 5' GUANIDINONALTRINDOLE; ACETAMIDE DERIVATIVE; ANTIDEPRESSANT AGENT; BINALTORPHIMINE; CITALOPRAM; COCAINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DESIPRAMINE; FLUOXETINE; KAPPA OPIATE RECEPTOR AGONIST; KAPPA OPIATE RECEPTOR ANTAGONIST; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; NALTRINDOLE; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEPRESSION; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; FORCED SWIMMING TEST; GENE EXPRESSION REGULATION; IMMOBILIZATION; LIGAND BINDING; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; REWARD;

ANIMALS; ANTIDEPRESSIVE AGENTS; MALE; MODELS, ANIMAL; MOTOR ACTIVITY; NARCOTIC ANTAGONISTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, KAPPA; SWIMMING;

EID: 0037381053     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.046433     Document Type: Article

References (40)

1. Carlezon WA Jr, Pliakas AM, Parrow AM, Detke MJ, Cohen BM, and Renshaw PF (2002) Antidepressant-like effects of cytidine in the forced swim test in rats. Biol Psychiatry 51:882-889.
2. Carlezon WA Jr, Thome J, Olson V, Lane-Ladd SB, Brodkin ES, Hiroi N, Duman RS, Neve RL, and Nestler EJ (1998) Regulation of cocaine reward by CREB. Science (Wash DC) 282:2272-2275.
3. Carlezon WA Jr, Todtenkopf MS, McPhie DL, Pimental P, Pliakas AM, Stellar JR, and Trzcinska M (2001) Repeated exposure to rewarding brain stimulation downregulates GluR1 expression in the ventral tegmental area. Neuropsychopharmacology 25:232-241.
4. Carlezon WA Jr and Wise RA (1996a) Microinjections of phencyclidine (PCP) and related drugs into nucleus accumbens shell potentiate medial forebrain bundle brain stimulation reward. Psychopharmacology 128:413-420.
5. Carlezon WA Jr and Wise RA (1996b) Rewarding actions of phencyclidine and related drugs in nucleus accumbens shell and frontal cortex. J Neurosci 16:3112-3122.
6. Cole RL, Konradi C, Douglass J, and Hyman SE (1995) Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum. Neuron 14:813-823.
7. Detke MJ, Rickels M, and Lucki I (1995) Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology 121:66-72.
8. Di Chiara G and Imperato A (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA 85:5274-5278.
9. Di Chiara G, Loddo P, and Tanda G (1999) Reciprocal changes in prefrontal and limbic dopamine responsiveness to aversive and rewarding stimuli after chronic mild stress: implications for the psychobiology of depression. Biol Psychiatry 46:1624-1633.
10. Duman RS (2002) Synaptic plasticity and mood disorders. Mol Psychiatry 7:S29-S34.
11. Gawin FH, Kleber HD, Byck R, Rounsaville BJ, Kosten TR, Jatlow PI, and Morgan C (1989) Desipramine facilitation of initial cocaine abstinence. Arch Gen Psychiatry 46:117-121.
12. Hall FS, Stellar JR, and Kelley AE (1990) Acute and chronic desipramine treatment effects on rewarding electrical stimulation of the lateral hypothalamus. Pharmacol Biochem Behav 37:277-281.
13. Hammer RP Jr, Pires WS, Markou A, and Koob GF (1993) Withdrawal following cocaine self-administratian decreases regional cerebral metabolic rate in critical brain reward regions. Synapse 14:73-80.
14. Jewett DC, Grace MK, Jones RM, Billington CJ, Portoghese PS, and Levine AS (2001) The κ-opioid antagonist GNTI reduces U50,488-, DAMGO- and deprivation-induced feeding, but not butorphanol- and neuropeptide Y-induced feeding in rats. Brain Res 909:75-80.
15. Jones DN and Holtzman SG (1992) Long term κ-opioid receptor blockade following nor-binaltorphimine. Eur J Pharmacol 215:345-348.
16. Jones RM and Portoghese PS (2000) 5′-Guanidinonaltrindole, a highly selective and potent κ-opioid receptor antagonist. Eur J Pharmacol 396:49-52.
17. Kreek MJ and Koob GF (1998) Drug dependence: stress and dysregulation of brain reward pathways. Drug Alcohol Depend 51:23-47.
18. Lee K and Kornetsky C (1998) Acute and chronic fluoxetine treatment decreases the sensitivity of rats to rewarding brain stimulation. Pharmacol Biochem Behav 60:539-544.
19. Maisonneuve IM, Archer S, and Glick SD (1994) U50,488, a κ-opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of rats. Neurosci Lett 181:57-60.
20. Manji H, Drevets WC, and Charney DS (2001) The cellular neurobiology of depression. Nat Med 7:541-547.
21. Markou A, Hauger RL, and Koob GF (1992) Desmethylimipramine attenuates cocaine withdrawal in rats. Psychopharmacology 109:305-314.
22. Miliaressis E, Rompre PP, Laviolette P, Philippe L, and Coulombe D (1986) The curve-shift paradigm in self-stimulation. Physiol Behav 37:85-91.
23. Negus SS, Mello NK, Linsenmayer DC, Jones RM, and Portoghese PS (2002) Kappa opioid antagonist effects of the novel κ-antagonist 5′-guanidinonaltrindole (GNTI) in an assay of schedule-controlled behavior in rhesus monkeys. Psychopharmacology 163:412-419.
24. Nestler EJ, Barrot M, DiLeone RJ, Eisch AJ, Gold SJ, and Monteggia LM (2002) Neurobiology of depression. Neuron 34:13-25.
25. Newton SS, Thome J, Wallace TL, Shirayama Y, Schlesinger L, Sakai N, Chen J, Neve R, Nestler EJ, and Duman RS (2002) Inhibition of cAMP response elementbinding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect. J Neurosci 22:10883-10890.
26. Pasquier DA, Kemper TL, Forbes WB, and Morgane PJ (1977) Dorsal raphe, substantia nigra and locus coeruleus: interconnections with each other and the neostriatum. Brain Res Bull 2:323-339.
27. Paulson PE, Camp DM, and Robinson TE (1991) Time course of transient behavioral depression and persistent behavioral sensitization in relation to regional brain monoamine concentrations during amphetamine withdrawal in rats. Psychopharmacology 103:480-492.
28. Paxinos G and Watson C (1986) The Rat Brain in Stereotaxic Coordinates, 2nd ed., Academic Press, San Diego.
29. Pfeiffer A, Brantl V, Herz A, and Emrich HM (1986) Psychotomimesis mediated by κ-opiate receptors. Science (Wash DC) 233:774-776.
30. Pliakas AM, Carlson R, Neve RL, Konradi C, Nestler EJ, and Carlezon WA Jr (2001) Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element binding protein expression in nucleus accumbens. J Neurosci 21:7397-7403.
31. Porsolt RD, Le Pichon M, and Jalfre M (1977) Depression: a new animal model sensitive to antidepressant treatments. Nature (Lond) 266:730-732.
32. Post RM, Kotin J, and Goodwin FK (1974) The effects of cocaine on depressed patients. Am J Psychiatry 131:511-516.
33. Ritz MC and Kuhar MJ (1989) Relationship between self-administration of amphetamine and monoamine receptors in brain: comparison with cocaine. J Pharmacol Exp Ther 248:1010-1017.
34. Shippenberg TS and Rea W (1997) Sensitization to the behavioral effects of cocaine: modulation by dynorphin and κ-opioid receptor agonists. Pharmacol Biochem Behav 57:449-455.
35. Spanagel R and Shippenberg TS (1993) Modulation of morphine-induced sensitization by endogenous κ-opioid systems in the rat. Neurosci Lett 153:232-236.
36. Stevens WC Jr, Jones RM, Subramanian G, Metzger TG, Ferguson DM, and Portoghese PS (2000) Potent and selective indolomorphinan antagonists of the κ-opioid receptor. J Med Chem 43:2759-2769.
37. Svingos AL, Colago EE, and Pickel VM (1999) Cellular sites for dynorphin activation of κ-opioid receptors in the rat nucleus accumbens shell. J Neurosci 19:1804-1813.
38. Wise RA (1982) Neuroleptics and operant behavior: The anhedonia hypothesis. Behav Brain Sci 5:39-87.
39. Wise RA (1998) Drug-activation of brain reward pathways. Drug Alcohol Depend 51:13-22.
40. Zhang XF, Hu XT, and White FJ (1998) Whole-cell plasticity in cocaine withdrawal: reduced sodium currents in nucleus accumbens neurons. J Neurosci 18:488-498.