The GABAA receptor gene family: New opportunities for drug development

Current Opinion in Drug Discovery and Development

Volumn 6, Issue 5, 2003, Pages 648-657

  Whiting, Paul J ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

Anesthesia; Anxiety; Benzodiazepine; Cognition; GABAA receptor; Transgenics

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 ETHYL 6,7 DIMETHOXY BETA CARBOLINE 3 CARBOXYLIC ACID METHYL ESTER; 7 TERT BUTYL 3 (2,5 DIFLUOROPHENYL) 6 (2 METHYL 2H 1,2,4 TRIAZOL 3 YLMETHOXY) 1,2,4 TRIAZOLO[4,3 B]PYRIDAZINE; ANESTHETIC AGENT; ANTICONVULSIVE AGENT; ANXIOLYTIC AGENT; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; BRETAZENIL; DIAZEPAM; ETOMIDATE; FLUMAZENIL; FLUNITRAZEPAM; GABOXADOL; INHALATION ANESTHETIC AGENT; INTRAVENOUS ANESTHETIC AGENT; ION CHANNEL; ISOFLURANE; LORAZEPAM; NEUROTRANSMITTER; PROGESTERONE; PROPOFOL; RECEPTOR SUBTYPE; SEDATIVE AGENT; UNCLASSIFIED DRUG; ZOLPIDEM; BENZODIAZEPINE;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; BINDING SITE; BRAIN; CHANNEL GATING; COGNITION; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG TARGETING; MAMMAL; MOUSE; MULTIGENE FAMILY; NONHUMAN; REVIEW; TRANSGENIC MOUSE; ANIMAL; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ANESTHETICS; ANIMALS; ANTI-ANXIETY AGENTS; BENZODIAZEPINES; BINDING SITES; BRAIN; DRUG DESIGN; ION CHANNEL GATING; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, GABA-A;

EID: 0142218355     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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