Gating of α3β4 neuronal nicotinic receptor can be controlled by the loop M2-M3 of both α3 and β4 subunits

Pflugers Archiv European Journal of Physiology

Volumn 439, Issue 1-2, 1999, Pages 86-92

  Rovira, José Carlos ^a   Vicente Agulló, Francisco ^a   Campos Caro, Antonio ^a   Criado, Manuel ^a   Sala, Francisco ^a   Sala, Salvador ^a   Ballesta, Juan José ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

Author keywords

Allosteric model; Binding; Gating; Neuronal nicotinic receptors; Single channel

Indexed keywords

ASPARAGINE; ASPARTIC ACID; EPIBATIDINE; LEUCINE; NICOTINE; NICOTINIC RECEPTOR; FUSED HETEROCYCLIC RINGS; NICOTINIC AGENT; NICOTINIC RECEPTOR ALPHA3BETA4; PYRIDINE DERIVATIVE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CHANNEL GATING; KINETICS; MATHEMATICAL COMPUTING; MEMBRANE CHANNEL; MEMBRANE CURRENT; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; XENOPUS LAEVIS; ANIMAL; CATTLE; CELL MEMBRANE POTENTIAL; CHEMICAL STRUCTURE; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; GENETICS; METABOLISM; PATCH CLAMP; PHYSIOLOGY; POINT MUTATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CATTLE; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; ION CHANNEL GATING; MEMBRANE POTENTIALS; MODELS, MOLECULAR; NICOTINIC AGONISTS; OOCYTES; PATCH-CLAMP TECHNIQUES; POINT MUTATION; PYRIDINES; RECEPTORS, NICOTINIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; XENOPUS LAEVIS;

EID: 0033253510     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240051131     Document Type: Article

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