Identification of amino acids in the nicotinic acetylcholine receptor agonist binding site and ion channel photolabeled by 4-[(3-trifluoromethyl)-3H-diazirin-3-yl] benzoylcholine, a novel photoaffinity antagonist

Biochemistry

Volumn 42, Issue 2, 2003, Pages 271-283

  Chiara, David C ^a   Trinidad, Jonathan C ^a   Wang, Dong ^a   Ziebell, Michael R ^a   Sullivan, Deirdre ^a   Cohen, Jonathan B ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID IDENTIFICATION;

BINDING ENERGY; CARBOXYLIC ACIDS; CHROMATOGRAPHY; ELECTROPHORESIS; ENZYMES; ESTERS; PROTEINS; ULTRAVIOLET RADIATION;

AMINO ACIDS;

4 [(3 TRIFLUOROMETHYL) 3H DIAZIRIN 3 YL]BENZOYLCHOLINE; CHOLINE DERIVATIVE; ION CHANNEL; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; ELECTRIC ORGAN; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY; RECEPTOR BINDING; TORPEDO CALIFORNICA;

ACETYLCHOLINE; AMINO ACID SEQUENCE; AMINO ACIDS; AMPHIBIAN VENOMS; ANIMALS; AZIRINES; BENZOYLCHOLINE; BINDING SITES; BINDING, COMPETITIVE; BUNGAROTOXINS; CELL MEMBRANE; CHOLINE; IODINE RADIOISOTOPES; ION CHANNELS; MOLECULAR SEQUENCE DATA; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; PEPTIDE FRAGMENTS; PHOTOAFFINITY LABELS; PROTEIN ISOFORMS; PROTEIN SUBUNITS; RECEPTORS, NICOTINIC; TORPEDO; TRITIUM; ULTRAVIOLET RAYS; XENOPUS;

ANIMALIA; TORPEDO CALIFORNICA;

EID: 0037457902     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0269815     Document Type: Article

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