A residue in the middle of the M2-M3 loop of the β4 subunit specifically affects gating of neuronal nicotinic receptors

FEBS Letters

Volumn 433, Issue 1-2, 1998, Pages 89-92

  Rovira, José Carlos ^a   Ballesta, Juan José ^a   Vicente Agulló, Francisco ^a   Campos Caro, Antonio ^a   Criado, Manuel ^a   Sala, Francisco ^a   Sala, Salvador ^a  

^a INSTITUTO DE NEUROCIENCIAS   (Spain)

Author keywords

3 4 Receptor; Binding and gating coupling; Neuronal nicotinic receptor; Single channel conductance

Indexed keywords

NICOTINIC RECEPTOR;

ANIMAL CELL; ARTICLE; CATTLE; CHANNEL GATING; ION CONDUCTANCE; ION CURRENT; NERVE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CATTLE; ELECTRIC CONDUCTIVITY; FEMALE; GENE EXPRESSION; HUMANS; ION CHANNEL GATING; KINETICS; MUTAGENESIS, SITE-DIRECTED; NEURONS; NICOTINIC AGONISTS; OOCYTES; POINT MUTATION; PYRIDINES; RATS; RECEPTORS, NICOTINIC; STRUCTURE-ACTIVITY RELATIONSHIP; TRITIUM; XENOPUS;

EID: 0031864943     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)00889-8     Document Type: Article

References (25)

1. Campos-Caro, A., Sala, S., Ballesta, J.J., Vicente-Agulló, F., Criado, M. and Sala, F. (1996) Proc. Natl. Acad. Sci. USA 93, 6118-6123.
2. Revah, F., Bertrand, D., Galzi, J.L., Devillers-Thiery, A., Mulle, C., Hussy, N., Bertrand, S., Ballivet, M. and Changeux, J.P. (1991) Nature 353, 846-849.
3. Campos-Caro, A., Smillie, F.I., Domínguez-del-Toro, E., Rovira, J.C., Vicente-Agulló, F., Chapuli, J., Juiz, J.M., Sala, S., Sala, F., Ballesta, J.J. and Criado, M. (1997) J. Neurochem. 68, 488-497.
4. Herlitze, S. and Koenen, M. (1990) Gene 91, 143-147.
5. García-Guzmán, M., Sala, F., Sala, S., Campos-Caro, A. and Criado, M. (1994) Biochemistry 33, 15198-15203.
6. Krieg, P.A. and Melton, D.A. (1984) Nucleic Acids Res. 12, 7057-7070.
7. Buller, A.L. and White, M.M. (1992) Methods Enzymol. 207, 368-375.
8. Houghtling, R.A., Davila-Garcia, M.I. and Kellar, K.J. (1995) Mol. Pharmacol. 48, 280-287.
9. Munson, P.J. and Rodbard, D. (1980) Anal. Biochem. 107, 220-239.
10. Anand, R., Conroy, W.G., Schoepfer, R., Whiting, P. and Lindstrom, J. (1991) J. Biol. Chem. 266, 11192-11198.
11. Yang, X.C. and Sachs, F. (1989) Science 243, 1068-1071.
12. Colquhoun, D. and Sakmann, B. (1985) J. Physiol. 369, 501-557.
13. Sine, S.M. and Steinbach, J.H. (1984) Biophys. J. 46, 277-283.
14. Papke, R.L. and Heinemann, S.F. (1991) J. Physiol. 440, 95-112.
15. Sivilotti, L.G., McNeil, D.K., Lewis, T.M., Nassar, M.A., Schoepfer, R. and Colquhoun, D. (1997) J. Physiol. 500, 123-138.
16. Colquhoun, D. and Hawkes, A.G. (1995) in: Single-Channel Recording (Sakmann, B. and Neher, E., Eds.), pp 589-633, Plenum Press, New York.
17. Imoto, K., Busch, C., Sakmann, B., Mishina, M., Konno, T., Nakai, J., Bujo, H., Mori, Y., Fukuda, K. and Numa, S. (1988) Nature 335, 645-648.
18. Luetje, C.W. and Patrick, J. (1991) J. Neurosci. 11, 837-845.
19. Papke, R.L., Duvoisin, R.M. and Heinemann, S.F. (1993) Proc. R. Soc. Lond. B Biol. Sci. 252, 141-148.
20. Figl, A., Cohen, B.N., Quick, M.W., Davidson, N. and Lester, H.A. (1992) FEBS Lett. 308, 245-248.
21. Hussy, N., Ballivet, M. and Bertrand, D. (1994) J. Neurophysiol. 72, 1317-1326.
22. Cachelin, A.B. and Rust, G. (1995) Pflugers Arch. 429, 449-451.
23. Unwin, N. (1995) Nature 373, 37-43.
24. Gready, J.E., Ranganathan, S., Schofield, P.R., Matsuo, Y. and Nishikawa, K. (1997) Protein Sci. 6, 983-998.
25. Rajendra, S., Lynch, J.W., Pierce, K.D., French, C.R., Barry, P.H. and Schofield, P.R. (1995) Neuron 14, 169-175.