Functional interactions between nicotinic and P2X channels in short-term cultures of guinea-pig submucosal neurons

Journal of Physiology

Volumn 513, Issue 3, 1998, Pages 671-683

  Barajas López, Carlos ^a   Espinosa Luna, Rosa ^b   Zhu, Yaohui ^b  

^a QUEEN S UNIVERSITY   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; CALCIUM ION; GENISTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE TRIPHOSPHATE; HEXAMETHONIUM; K 252A; MAGNESIUM ION; N ETHYLMALEIMIDE; NICOTINIC RECEPTOR; PURINE P2X RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; SODIUM ION; STAUROSPORINE; GUANINE NUCLEOTIDE BINDING PROTEIN; PURINERGIC P2X RECEPTOR;

ANIMAL CELL; ARTICLE; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; FEMALE; GUINEA PIG; ION TRANSPORT; MALE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SUBMUCOSA; TEMPERATURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; CONCENTRATION (PARAMETERS); DESENSITIZATION; HYPERPOLARIZATION; PHARMACOLOGICAL BLOCKING; PROTEIN PHOSPHORYLATION; RECEPTOR OCCUPANCY; WHOLE CELL;

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; ANIMALS; CATIONS; CELLS, CULTURED; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; FEMALE; GUINEA PIGS; INTESTINAL MUCOSA; ION CHANNEL GATING; ION CHANNELS; KINETICS; MALE; MEMBRANE POTENTIALS; NEURONS; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; RECEPTORS, NICOTINIC; RECEPTORS, PURINERGIC P2;

EID: 0032535426     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1998.671ba.x     Document Type: Article

References (30)

1. ALLENDE, G., FRANCO, R., MALLOL, J., LLUIS, C. & CANELA, E. I. (1991). N-ethylmaleimide affects agonist binding to A1 adenosine receptors differently in the presence than in the absence of ligand. Biochemical and Biophysical Research Communications 181, 213-218.
2. ASCHER, P., LARGE, W. A. & RANG, H. P. (1979). Studies on the mechanism of action of acetyleholine antagonists on rat parasympathetic ganglion cells. Journal of Physiology 295, 139-170.
3. BARAJAS-LÓPEZ, C. (1993). Adenosine reduces the potassium conductance of guinea-pig submucosal plexus neurons by activating protein kinase A. Pflügers Archiv 424, 410-415.
4. BARAJAS-LÓPEZ, C., ESPINOSA-LUNA, R. & GERZANICH, V. (1994). ATP closes a potassium and opens a cationic conductance through different receptors in neurons of guinea-pig submucous plexus. Journal of Pharmacology and Experimental Therapeutics 268, 1396-1402.
5. BARAJAS-LÓPEZ, C., HUIZINGA, J. D., COLLINS, S. M., GERZANICH, V., ESPINOSA-LUNA, R. & PERES, A. L. (1996a). P2x-purinoceptors of myenteric neurons from the guinea-pig ileum and their unusual pharmacological properties. British Journal of Pharmacology 119, 1541-1548.
6. BARAJAS-LÓPEZ, C., PERES, A. L. & ESPINOSA-LUNA, R. (1996b). Cellular mechanisms underlying adenosine actions on cholinergic transmission in enteric neurons. American Journal of Physiology 271, C264-275.
7. BARAJAS-LÓPEZ, C., PERES, A. L., ESPINOSA-LUNA, R., REYES-VAZQUEZ, C. & PRIETO-GOMEZ, B. (1996c). Melatonin modulates cholinergic transmission by blocking nicotinic channels in the guinea-pig submucous plexus. European Journal of Pharmacology 312, 319-325.
8. BEAN, B. P. (1992). Pharmacology and electrophysiology of ATP-activated ion channels. Trends in Pharmacological Sciences 13, 87-90.
9. BERTRAND, D., BALLIVET, M. & RUNGGER, D. (1990). Activation and blocking of neuronal nicotinic acetylcholine receptor reconstituted in Xenopus oocytes. Proceedings of the National Academy of Sciences of the USA 87, 1993-1997.
10. BRAKE, A. J., WAGENBACH, M. J. & JULIUS, D. (1994). New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature 371, 519-523.
11. BUCKLEY, N. J. & CAULFIELD, M. (1992). Transmission: acetylcholine. In Autonomic Neuroeffector Mechanisms, ed. BURNSTOCK, G. & HOYLE, C. H. V., pp. 277-322. Hardwood Academic Publishers, Chur, Switzerland.
12. BURNSTOCK, G. (1997). The past, present and future of purine nucleotides as signalling molecules. Neuropharmacology 36, 1127-1139.
13. 2+ signaling in myenteric neurons via P2 purinoceptors. American Journal of Physiology 272, G463-473.
14. EVANS, R. J., DERKACH, V. & SURPRENANT, A. (1992). ATP mediates fast synaptic transmission in mammalian neurons. Nature 357, 503-505.
15. KASE, H., IWAHASHI, K., NAKANISHI, S., MATSUDA, Y., YAMADA, K., TAKAHASHI, M., SATO, A. & KANEKO, M. (1987). K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochemical and Biophysical Research Communications 142, 436-440.
16. LINDSTRÖM, J. (1996). Neuronal nicotinic acetylcholine receptors. Ion Channels 4, 377-450.
17. LINDSTRÖM, J., ANAND, R., GERZANICH, V., PENG, X., WANG, F. & WELLS, G. (1996). Structure and function of neuronal nicotinic acetylcholine receptors. Progress in Brain Research 109, 125-137.
18. LIU, H., LI, K. & SPERELAKIS, N. (1997). Tyrosine kinase inhibitor, genistein, inhibits macroscopic L-type calcium current in rat portal vein smooth muscle cells. Canadian Journal of Physiology and Pharmacology 75, 1058-1062.
19. NAKAZAWA, K. (1994a). ATP-activated current and its interaction with acetylcholine-activated current in rat sympathetic neurons. Journal of Neuroscience 14, 740-750.
20. NAKAZAWA, K. (1994b). Modulation of the inhibitory action of ATP on acetylcholine-activated current by protein phosphorylation in rat sympathetic neurons. Pflügers Archiv 427, 129-135.
21. NAKAZAWA, K., FUJIMORI, K., TAKANAKA, A. & INOUE, K. (1991). Comparison of adenosine triphosphate- and nicotine-activated inward currents in rat phaeochromocytoma cells (published erratum appears in Journal of Physiology 440, 771 (1991)). Journal of Physiology 434, 647-660.
22. NISHI, S. & NORTH, R. A. (1973). Intracellular recording from the myenteric plexus of the guinea-pig ileum. Journal of Physiology 231, 471-491.
23. NORTH, R. A. (1996). P2X receptors: a third major class of ligand-gated ion channels. Ciba Foundation Symposium 198, 91-105.
24. 2+ channels by PTX-sensitive G-proteins is blocked by N-ethylmaleimide in rat sympathetic neurons. Journal of Neuroscience 14, 7109-7116.
25. SHENG, M. & KIM, E. (1996). Ion channel associated proteins. Current Opinion in Neurobiology 6, 602-608.
26. SILINSKY, E. M. & GERZANICH, V. (1993). On the excitatory effects of ATP and its role as a neurotransmitter in coeliac neurons of the guinea-pig. Journal of Physiology 464, 197-212.
27. SURPRENANT, A., BUELL, G. & NORTH, R. A. (1995). P2X receptors bring new structure to ligand-gated ion channels. Trends in Neurosciences 18, 224-229.
28. TROUSLARD, J., MIRSKY, R., JESSEN, K. R., BURNSTOCK, G. & BROWN, D. A. (1993). Intracellular calcium changes associated with cholinergic nicotinic receptor activation in cultured myenteric plexus neurones. Brain Research 624, 103-108.
29. ZHOU, X. & GALLIGAN, J. J. (1996). P2X purinoceptors in cultured myenteric neurons of guinea-pig small intestine. Journal of Physiology 496, 719-729.
30. ZHOU, X & GALLIGAN, J. J (1997). Interaction between P2X and nicotinic cholinergic receptors (NAChR's) in cultured myenteric neurons from guinea pig small intestine. Gastroenterology 112, A858.