메뉴 건너뛰기




Volumn 45, Issue 3, 2005, Pages 395-404

Cryptococcus neoformans: A sugar-coated killer with designer genes

Author keywords

Cryptococcus; Genes; Molecular biology; Pathogenesis; Virulence

Indexed keywords

MELANIN; SUGAR;

EID: 24344500521     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.femsim.2005.06.005     Document Type: Short Survey
Times cited : (88)

References (126)
  • 2
    • 0035344886 scopus 로고    scopus 로고
    • Serologic evidence for cryptococcus infection in early childhood
    • D.L. Goldman, H. Khine, and J. Abadi Serologic evidence for cryptococcus infection in early childhood Pediatrics 107 2001 66
    • (2001) Pediatrics , vol.107 , pp. 66
    • Goldman, D.L.1    Khine, H.2    Abadi, J.3
  • 3
    • 0012104487 scopus 로고
    • Decline in the incidence of cryptococcosis among HIV-related patients
    • J.I. McNeill, and V.L. Kan Decline in the incidence of cryptococcosis among HIV-related patients J. Acqu. Im. Def. Synd. Human Retro 206 1995 207 208
    • (1995) J. Acqu. Im. Def. Synd. Human Retro , vol.206 , pp. 207-208
    • McNeill, J.I.1    Kan, V.L.2
  • 4
    • 0033021986 scopus 로고    scopus 로고
    • Cryptococcosis: Population-based multistate active surveillance and risk factors in human immunodeficiency virus-infected persons. Cryptococcal Active Surveillance Group
    • A. Hajjman, L.A. Conn, and D.S. Stephens Cryptococcosis: population-based multistate active surveillance and risk factors in human immunodeficiency virus-infected persons. Cryptococcal Active Surveillance Group J. Infect. Dis. 179 1999 449 454
    • (1999) J. Infect. Dis. , vol.179 , pp. 449-454
    • Hajjman, A.1    Conn, L.A.2    Stephens, D.S.3
  • 5
    • 0034491480 scopus 로고    scopus 로고
    • Declining number of patients with cryptococcosis in the Netherlands in the era of highly active antiretroviral therapy
    • L.J. van Elden, A.M. Walenkamp, and M.M. Lipovsky Declining number of patients with cryptococcosis in the Netherlands in the era of highly active antiretroviral therapy AIDS 14 2000 2787 2788
    • (2000) AIDS , vol.14 , pp. 2787-2788
    • Van Elden, L.J.1    Walenkamp, A.M.2    Lipovsky, M.M.3
  • 8
    • 0021281103 scopus 로고
    • Acquired immunodeficiency syndrome in Rwanda
    • P. Van de Perre, P. Lepage, and P. Kestelyn Acquired immunodeficiency syndrome in Rwanda Lancet 2 1984 62 65
    • (1984) Lancet , vol.2 , pp. 62-65
    • Van De Perre, P.1    Lepage, P.2    Kestelyn, P.3
  • 9
    • 0033925332 scopus 로고    scopus 로고
    • Impact of HIV infection on meningitis in Harare, Zimbabwe: A prospective study of 406 predominantly adult patients
    • J.G. Hakim, I.T. Gangaidzo, and R.S. Heyderman Impact of HIV infection on meningitis in Harare, Zimbabwe: a prospective study of 406 predominantly adult patients AIDS 14 2000 1401 1407
    • (2000) AIDS , vol.14 , pp. 1401-1407
    • Hakim, J.G.1    Gangaidzo, I.T.2    Heyderman, R.S.3
  • 10
    • 0036948447 scopus 로고    scopus 로고
    • Genetics of Cryptococcus neoformans
    • C.M. Hull, and J. Heitman Genetics of Cryptococcus neoformans Ann. Rev. Genet. 36 2002 557 615
    • (2002) Ann. Rev. Genet. , vol.36 , pp. 557-615
    • Hull, C.M.1    Heitman, J.2
  • 11
    • 0026334016 scopus 로고
    • Genetic association of mating types and virulence in Cryptococcus neoformans
    • C.J. Kwon-Chung, J.C. Edman, and B.L. Wickes Genetic association of mating types and virulence in Cryptococcus neoformans Infect. Immun. 60 1992 602 605
    • (1992) Infect. Immun. , vol.60 , pp. 602-605
    • Kwon-Chung, C.J.1    Edman, J.C.2    Wickes, B.L.3
  • 12
    • 0041971075 scopus 로고    scopus 로고
    • Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates
    • K. Nielsen, G.M. Cox, P. Wang, D.L. Toffaletti, J.R. Perfect, and J. Heitman Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates Infect. Immun. 71 9 2003 4831 4841
    • (2003) Infect. Immun. , vol.71 , Issue.9 , pp. 4831-4841
    • Nielsen, K.1    Cox, G.M.2    Wang, P.3    Toffaletti, D.L.4    Perfect, J.R.5    Heitman, J.6
  • 13
    • 0018196299 scopus 로고
    • Distribution of "alpha" and "a" mating types of Cryptococcus neoformans among natural and clinical isolates
    • K.J. Kwon-Chung, and J.E. Bennett Distribution of "alpha" and "a" mating types of Cryptococcus neoformans among natural and clinical isolates Am. J. Med. 108 1978 337 340
    • (1978) Am. J. Med. , vol.108 , pp. 337-340
    • Kwon-Chung, K.J.1    Bennett, J.E.2
  • 14
    • 0037487244 scopus 로고    scopus 로고
    • A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans
    • R.C. Davidson, C.B. Nichols, G.M. Cox, J.R. Perfect, and J. Heitman A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans Mol. Microbiol. 49 2 2003 469 485
    • (2003) Mol. Microbiol. , vol.49 , Issue.2 , pp. 469-485
    • Davidson, R.C.1    Nichols, C.B.2    Cox, G.M.3    Perfect, J.R.4    Heitman, J.5
  • 15
    • 0034687743 scopus 로고    scopus 로고
    • Identification of the MATa mating-type locus of Cryptococcus neoformans reveals a serotype a MATa strain thought to have been extinct
    • K.B. Lengeler, P. Wang, G.M. Cox, J.R. Perfect, and J. Heitman Identification of the MATa mating-type locus of Cryptococcus neoformans reveals a serotype A MATa strain thought to have been extinct Proc. Natl. Acad. Sci. 97 26 2000 14455 14460
    • (2000) Proc. Natl. Acad. Sci. , vol.97 , Issue.26 , pp. 14455-14460
    • Lengeler, K.B.1    Wang, P.2    Cox, G.M.3    Perfect, J.R.4    Heitman, J.5
  • 16
    • 0033986793 scopus 로고    scopus 로고
    • The G-protein beta subunit GPB1 is required for mating and haploid fruiting in Cryptococcus neoformans
    • P. Wang, J.R. Perfect, and J. Heitman The G-protein beta subunit GPB1 is required for mating and haploid fruiting in Cryptococcus neoformans Mol. Cell Biol. 20 2000 352 362
    • (2000) Mol. Cell Biol. , vol.20 , pp. 352-362
    • Wang, P.1    Perfect, J.R.2    Heitman, J.3
  • 17
    • 0028314482 scopus 로고
    • Restriction fragment length polymorphism analysis of Cryptococcus neoformans isolates from environmental (pigeon excreta) and clinical sources in New York City
    • B.P. Currie, L.F. Freundlich, and A. Casadevall Restriction fragment length polymorphism analysis of Cryptococcus neoformans isolates from environmental (pigeon excreta) and clinical sources in New York City J. Clin. Microbiol. 32 1994 1188 1192
    • (1994) J. Clin. Microbiol. , vol.32 , pp. 1188-1192
    • Currie, B.P.1    Freundlich, L.F.2    Casadevall, A.3
  • 18
    • 0035152552 scopus 로고    scopus 로고
    • Prospective use of RFLP analysis on amplified Cryptococcus neoformans URA5 gene sequences for rapid identification of varieties and serotypes in clinical samples
    • A. Velegraki, V.G. Klosses, A. Kansovzidov, S. Smilakov, A. Mitroussia-Ziouua, and N.J. Legakis Prospective use of RFLP analysis on amplified Cryptococcus neoformans URA5 gene sequences for rapid identification of varieties and serotypes in clinical samples Med. Mycol. 39 2004 409 417
    • (2004) Med. Mycol. , vol.39 , pp. 409-417
    • Velegraki, A.1    Klosses, V.G.2    Kansovzidov, A.3    Smilakov, S.4    Mitroussia-Ziouua, A.5    Legakis, N.J.6
  • 20
    • 0027526237 scopus 로고
    • Persistence of initial infection in recurrent Cryptococcus neoformans meningitis
    • E.D. Spitzer, S.G. Spitzer, L.F. Freundlich, and A. Casadevall Persistence of initial infection in recurrent Cryptococcus neoformans meningitis Lancet 341 1993 595 596
    • (1993) Lancet , vol.341 , pp. 595-596
    • Spitzer, E.D.1    Spitzer, S.G.2    Freundlich, L.F.3    Casadevall, A.4
  • 22
    • 0033675677 scopus 로고    scopus 로고
    • Multiple gene genealogies reveal recent dispersion and hybridization in the human fungus, Cryptococcus neoformans
    • J. Xu, R. Vilgalys, and T.G. Mitchell Multiple gene genealogies reveal recent dispersion and hybridization in the human fungus, Cryptococcus neoformans Mol. Ecol. 9 2002 1471 1481
    • (2002) Mol. Ecol. , vol.9 , pp. 1471-1481
    • Xu, J.1    Vilgalys, R.2    Mitchell, T.G.3
  • 23
    • 0032585880 scopus 로고    scopus 로고
    • The STE12α homolog is required for haploid filamentation but dispensable for mating and virulence in Cryptococcus neoformans
    • C. Yue, L. Cavallo, J.A. Alspaugh, G.M. Cox, J.R. Perfect, and J. Heitman The STE12α homolog is required for haploid filamentation but dispensable for mating and virulence in Cryptococcus neoformans Genetics 153 1999 1601 1615
    • (1999) Genetics , vol.153 , pp. 1601-1615
    • Yue, C.1    Cavallo, L.2    Alspaugh, J.A.3    Cox, G.M.4    Perfect, J.R.5    Heitman, J.6
  • 24
    • 0035853109 scopus 로고    scopus 로고
    • The second STE12 homologue of Cryptococcus neoformans is MAT a-specific and plays an important role in virulence
    • Y.C. Chang, L.A. Penoyer, and K.J. Kwon-Chung The second STE12 homologue of Cryptococcus neoformans is MAT a-specific and plays an important role in virulence Proc. Natl. Acad. Sci. 98 2001 3258 3263
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 3258-3263
    • Chang, Y.C.1    Penoyer, L.A.2    Kwon-Chung, K.J.3
  • 25
    • 0036548308 scopus 로고    scopus 로고
    • Mating type specific and nonspecific PAK kinases play shared and divergent role in cytokinesis, differentiation and virulence of Cryptococcus neoformans
    • P. Wang, C.S. Nichols, K.B. Lengeler, M.E. Cardenas, G.M. Cox, J.R. Perfect, and J. Heitman Mating type specific and nonspecific PAK kinases play shared and divergent role in cytokinesis, differentiation and virulence of Cryptococcus neoformans Eukaryot. Cell 1 2002 257 272
    • (2002) Eukaryot. Cell , vol.1 , pp. 257-272
    • Wang, P.1    Nichols, C.S.2    Lengeler, K.B.3    Cardenas, M.E.4    Cox, G.M.5    Perfect, J.R.6    Heitman, J.7
  • 26
    • 1242322514 scopus 로고    scopus 로고
    • Cyclic AMP-dependent protein kinase catalytic subunits have divergent roles in virulence factor production in two varieties of the fungal pathogen Cryptococcus neoformans
    • J.K. Hicks, C. D'Souza, G.M. Cox, and J. Heitman Cyclic AMP-dependent protein kinase catalytic subunits have divergent roles in virulence factor production in two varieties of the fungal pathogen Cryptococcus neoformans Eukaryot. Cell 3 2004 14 28
    • (2004) Eukaryot. Cell , vol.3 , pp. 14-28
    • Hicks, J.K.1    D'Souza, C.2    Cox, G.M.3    Heitman, J.4
  • 28
    • 0035119757 scopus 로고    scopus 로고
    • New dominant selectable marker for use in Cryptococcus neoformans
    • H.C. McDade, and G.M.A. Cox new dominant selectable marker for use in Cryptococcus neoformans Med. Mycol. 39 2002 151 154
    • (2002) Med. Mycol. , vol.39 , pp. 151-154
    • McDade, H.C.1    Cox, G.M.A.2
  • 29
    • 0033970530 scopus 로고    scopus 로고
    • Development of positive selectable markers for the fungal pathogen Cryptococcus neoformans
    • J. Hua, J.D. Meyer, and J.K. Lodge Development of positive selectable markers for the fungal pathogen Cryptococcus neoformans Clin. Diagn. Lab Immunol. 7 1 2000 125 128
    • (2000) Clin. Diagn. Lab Immunol. , vol.7 , Issue.1 , pp. 125-128
    • Hua, J.1    Meyer, J.D.2    Lodge, J.K.3
  • 30
    • 79961163503 scopus 로고    scopus 로고
    • Dominant selection system for use in Cryptococcus neoformans
    • G.M. Cox, D.L. Toffaletti, and J.R. Perfect Dominant selection system for use in Cryptococcus neoformans J. Med. Vet. Mycol. 34 1996 385 391
    • (1996) J. Med. Vet. Mycol. , vol.34 , pp. 385-391
    • Cox, G.M.1    Toffaletti, D.L.2    Perfect, J.R.3
  • 32
    • 0025079475 scopus 로고
    • Isolation of the URA5 gene from Cryptococcus neoformans var. neoformans and its use as a selective marker for transformation
    • J.C. Edman, and K.J. Kwon-Chung Isolation of the URA5 gene from Cryptococcus neoformans var. neoformans and its use as a selective marker for transformation Mol. Cell Biol. 10 1990 4538 4544
    • (1990) Mol. Cell Biol. , vol.10 , pp. 4538-4544
    • Edman, J.C.1    Kwon-Chung, K.J.2
  • 33
    • 4143077083 scopus 로고    scopus 로고
    • Cryptococcus neoformans virulence gene discovery through insertional mutagenesis
    • A. Idnurm, J.L. Reedy, J.C. Nussbaum, and J. Heitman Cryptococcus neoformans virulence gene discovery through insertional mutagenesis Eukaryot. Cell 3 2 2004 420 429
    • (2004) Eukaryot. Cell , vol.3 , Issue.2 , pp. 420-429
    • Idnurm, A.1    Reedy, J.L.2    Nussbaum, J.C.3    Heitman, J.4
  • 35
    • 0032900947 scopus 로고    scopus 로고
    • Topoisomerase 1 is essential in Cryptococcus neoformans: Role in pathobiology and as an antifungal target
    • M. Del Poeta, D.L. Toffaletti, T.H. Rude, C.C. Dykstra, J. Heitman, and J.R. Perfect Topoisomerase 1 is essential in Cryptococcus neoformans: role in pathobiology and as an antifungal target Genetics 152 1999 167 178
    • (1999) Genetics , vol.152 , pp. 167-178
    • Del Poeta, M.1    Toffaletti, D.L.2    Rude, T.H.3    Dykstra, C.C.4    Heitman, J.5    Perfect, J.R.6
  • 36
    • 0036148819 scopus 로고    scopus 로고
    • Antisense repression in Cryptococcus neoformans as a laboratory tool and potential antifungal strategy
    • J.M. Gorlach, H.C. McDade, J.R. Perfect, and G.M. Cox Antisense repression in Cryptococcus neoformans as a laboratory tool and potential antifungal strategy Microbiology 148 2002 213 219
    • (2002) Microbiology , vol.148 , pp. 213-219
    • Gorlach, J.M.1    McDade, H.C.2    Perfect, J.R.3    Cox, G.M.4
  • 37
    • 0036188983 scopus 로고    scopus 로고
    • RNA interference in the pathogenic fungus Cryptococcus neoformans
    • H. Liu, T.R. Cottrell, L.M. Pierini, W.E. Goldman, and T.L. Doering RNA interference in the pathogenic fungus Cryptococcus neoformans Genetics 160 2 2002 463 470
    • (2002) Genetics , vol.160 , Issue.2 , pp. 463-470
    • Liu, H.1    Cottrell, T.R.2    Pierini, L.M.3    Goldman, W.E.4    Doering, T.L.5
  • 38
    • 0024041593 scopus 로고
    • Molecular Koch's postulates applied to microbial pathogenicity
    • S. Falkow Molecular Koch's postulates applied to microbial pathogenicity Dev. Infect. Dis. 10 2 1988 5274 5276
    • (1988) Dev. Infect. Dis. , vol.10 , Issue.2 , pp. 5274-5276
    • Falkow, S.1
  • 39
    • 0035102985 scopus 로고    scopus 로고
    • Identification of virulence mutants of the fungal pathogen Cryptococcus neoformans using signature-tagged mutagenesis
    • R.T. Nelson, J. Hua, B. Pryor, and J.K. Lodge Identification of virulence mutants of the fungal pathogen Cryptococcus neoformans using signature-tagged mutagenesis Genetics 157 2001 935 947
    • (2001) Genetics , vol.157 , pp. 935-947
    • Nelson, R.T.1    Hua, J.2    Pryor, B.3    Lodge, J.K.4
  • 41
    • 0141669024 scopus 로고    scopus 로고
    • Role of alternative oxidase gene in pathogenesis of Cryptococcus neoformans variety grubii
    • S. Akhter, H.C. McDade, J.M. Gorlach, G. Heinrich, G.M. Cox, and J.R. Perfect Role of alternative oxidase gene in pathogenesis of Cryptococcus neoformans variety grubii Infect. Immun. 71 2003 4831 4841
    • (2003) Infect. Immun. , vol.71 , pp. 4831-4841
    • Akhter, S.1    McDade, H.C.2    Gorlach, J.M.3    Heinrich, G.4    Cox, G.M.5    Perfect, J.R.6
  • 42
    • 0035047590 scopus 로고    scopus 로고
    • Cyclic-AMP-dependent protein kinase controls virulence of the fungal pathogen, Cryptococcus neoformans
    • C.A. D'Souza, J.A. Alspaugh, C. Yue, T. Harashima, G.M. Cox, J.R. Perfect, and J. Heitman Cyclic-AMP-dependent protein kinase controls virulence of the fungal pathogen, Cryptococcus neoformans Mol. Cell Biol. 21 2001 3179 3191
    • (2001) Mol. Cell Biol. , vol.21 , pp. 3179-3191
    • D'Souza, C.A.1    Alspaugh, J.A.2    Yue, C.3    Harashima, T.4    Cox, G.M.5    Perfect, J.R.6    Heitman, J.7
  • 44
    • 0036786526 scopus 로고    scopus 로고
    • Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans
    • T.H. Rude, D.L. Toffaletti, G.M. Cox, and J.R. Perfect Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans Infect. Immun. 70 2002 5684 5694
    • (2002) Infect. Immun. , vol.70 , pp. 5684-5694
    • Rude, T.H.1    Toffaletti, D.L.2    Cox, G.M.3    Perfect, J.R.4
  • 46
    • 0030668723 scopus 로고    scopus 로고
    • Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP
    • J.A. Alspaugh, J.R. Perfect, and J. Heitman Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP Genes Dev. 11 1997 3206 3217
    • (1997) Genes Dev. , vol.11 , pp. 3206-3217
    • Alspaugh, J.A.1    Perfect, J.R.2    Heitman, J.3
  • 48
    • 0028321560 scopus 로고
    • Complementation of a capsule-deficiency mutation of Cryptococcus neoformans restores its virulence
    • Y.C. Chang, and K.J. Kwon-Chung Complementation of a capsule-deficiency mutation of Cryptococcus neoformans restores its virulence Mol. Cell Biol. 14 1994 4912 4919
    • (1994) Mol. Cell Biol. , vol.14 , pp. 4912-4919
    • Chang, Y.C.1    Kwon-Chung, K.J.2
  • 49
    • 0031924971 scopus 로고    scopus 로고
    • Isolation of the third capsule-associated gene, CAP60, required for virulence in Cryptococcus neoformans
    • Y.C. Chang, and K.J. Kwon-Chung Isolation of the third capsule-associated gene, CAP60, required for virulence in Cryptococcus neoformans Infect. Immun. 66 1998 2230 2236
    • (1998) Infect. Immun. , vol.66 , pp. 2230-2236
    • Chang, Y.C.1    Kwon-Chung, K.J.2
  • 50
    • 0029886340 scopus 로고    scopus 로고
    • The second capsule gene of Cryptococcus neoformans, CAP 64, is essential for virulence
    • Y.C. Chang, L.A. Penoyer, and K.J. Kwon-Chung The second capsule gene of Cryptococcus neoformans, CAP 64, is essential for virulence Infect. Immun. 64 1996 1977 1983
    • (1996) Infect. Immun. , vol.64 , pp. 1977-1983
    • Chang, Y.C.1    Penoyer, L.A.2    Kwon-Chung, K.J.3
  • 51
    • 0032836047 scopus 로고    scopus 로고
    • Isolation, characterization, and localization of a capsule-associated gene, CAP10, of Cryptococcus neoformans
    • Y.C. Chang, and K.J. Kwon-Chung Isolation, characterization, and localization of a capsule-associated gene, CAP10, of Cryptococcus neoformans J. Bacteriol. 181 1999 5636 5643
    • (1999) J. Bacteriol. , vol.181 , pp. 5636-5643
    • Chang, Y.C.1    Kwon-Chung, K.J.2
  • 52
    • 0034768441 scopus 로고    scopus 로고
    • Cas1p is a membrane protein necessary for the o-acetylation of the Cryptococcus neoformans capsular polysaccharide
    • G. Janbon, U. Himmelreich, F. Moyrand, L. Improvisi, and F. Dromer Cas1p is a membrane protein necessary for the o-acetylation of the Cryptococcus neoformans capsular polysaccharide Mol. Microbiol. 42 2001 453 467
    • (2001) Mol. Microbiol. , vol.42 , pp. 453-467
    • Janbon, G.1    Himmelreich, U.2    Moyrand, F.3    Improvisi, L.4    Dromer, F.5
  • 53
    • 0035047590 scopus 로고    scopus 로고
    • CAMP dependent protein kinase controls virulence of the fungal pathogen, Cryptococcus neoformans
    • C. D'Souza, J.A. Alspaugh, C. Yue, G.M. Cox, J.R. Perfect, and J. Heitman cAMP dependent protein kinase controls virulence of the fungal pathogen, Cryptococcus neoformans Mol. Cell Biol. 21 2001 3179 3191
    • (2001) Mol. Cell Biol. , vol.21 , pp. 3179-3191
    • D'Souza, C.1    Alspaugh, J.A.2    Yue, C.3    Cox, G.M.4    Perfect, J.R.5    Heitman, J.6
  • 54
    • 0031692325 scopus 로고    scopus 로고
    • Organ-dependent variation of capsule thickness in Cryptococcus neoformans during experimental murine infection
    • J. Rivera, M. Feldmesser, M. Cammer, and A. Casadevall Organ-dependent variation of capsule thickness in Cryptococcus neoformans during experimental murine infection Infect. Immun. 66 1998 5027 5030
    • (1998) Infect. Immun. , vol.66 , pp. 5027-5030
    • Rivera, J.1    Feldmesser, M.2    Cammer, M.3    Casadevall, A.4
  • 55
    • 2542599333 scopus 로고    scopus 로고
    • Cryptococcus neoformans capsule structure evolution in vitro and during murine infection
    • D. Garcia-Hermoso, F. Dromer, and G. Janbon Cryptococcus neoformans capsule structure evolution in vitro and during murine infection Infect. Immun. 72 2004 3359 3365
    • (2004) Infect. Immun. , vol.72 , pp. 3359-3365
    • Garcia-Hermoso, D.1    Dromer, F.2    Janbon, G.3
  • 56
    • 0344826555 scopus 로고    scopus 로고
    • Cell wall alpha-1,3 glucan is required to anchor the Cryptococcus neoformans capsule
    • A.J. Reese, and T.L. Doering Cell wall alpha-1,3 glucan is required to anchor the Cryptococcus neoformans capsule Mol. Microbiol. 50 2003 1401 1409
    • (2003) Mol. Microbiol. , vol.50 , pp. 1401-1409
    • Reese, A.J.1    Doering, T.L.2
  • 57
    • 0037373742 scopus 로고    scopus 로고
    • Biosynthesis of fungal melanins and their importance for human pathogenic fungi
    • K. Langfelder, M. Streibel, B. John, G. Haase, and A. Brakhage Biosynthesis of fungal melanins and their importance for human pathogenic fungi Fungal Genet. Biol. 38 2003 143 158
    • (2003) Fungal Genet. Biol. , vol.38 , pp. 143-158
    • Langfelder, K.1    Streibel, M.2    John, B.3    Haase, G.4    Brakhage, A.5
  • 60
    • 0344826573 scopus 로고    scopus 로고
    • CLC-type chloride channel gene is required for laccase activity and virulence in Cryptococcus neoformans
    • X. Zhu, and P.R.A. Williamson CLC-type chloride channel gene is required for laccase activity and virulence in Cryptococcus neoformans Mol. Microbiol. 50 2003 1271 1281
    • (2003) Mol. Microbiol. , vol.50 , pp. 1271-1281
    • Zhu, X.1    Williamson, P.R.A.2
  • 62
    • 0036667450 scopus 로고    scopus 로고
    • Molecular and genetic analysis of the Cryptococcus neoformans MET3 gene and a met3 mutant
    • Z. Yang, R.C. Pascon, J.A. Alspaugh, G.M. Cox, and J.H. McCusker Molecular and genetic analysis of the Cryptococcus neoformans MET3 gene and a met3 mutant Microbiology 148 2002 2617 2625
    • (2002) Microbiology , vol.148 , pp. 2617-2625
    • Yang, Z.1    Pascon, R.C.2    Alspaugh, J.A.3    Cox, G.M.4    McCusker, J.H.5
  • 63
    • 7744228484 scopus 로고    scopus 로고
    • Cryptococcus neoformans mitochondrial genomes from serotype a and D strains do not influence virulence
    • D.L. Toffaletti, K. Nielsen, F. Dietrich, J. Heitman, and J.R. Perfect Cryptococcus neoformans mitochondrial genomes from serotype A and D strains do not influence virulence Curr. Genet. 46 2004 193 204
    • (2004) Curr. Genet. , vol.46 , pp. 193-204
    • Toffaletti, D.L.1    Nielsen, K.2    Dietrich, F.3    Heitman, J.4    Perfect, J.R.5
  • 64
    • 0034823836 scopus 로고    scopus 로고
    • Cryptococcus neoformans var. neoformans (serotype D) strains are more susceptible to heat than C. neoformans var. grubii (serotype a strains)
    • L.R. Martinez, J. Garcia-Rivera, and A. Casadevall Cryptococcus neoformans var. neoformans (serotype D) strains are more susceptible to heat than C. neoformans var. grubii (serotype A strains) J. Clin. Microbiol. 39 2001 3365 3367
    • (2001) J. Clin. Microbiol. , vol.39 , pp. 3365-3367
    • Martinez, L.R.1    Garcia-Rivera, J.2    Casadevall, A.3
  • 65
    • 0022635758 scopus 로고
    • Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans
    • K.J. Kwon-Chung, and J.C. Rhodes Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans Infect. Immun. 51 1986 218 223
    • (1986) Infect. Immun. , vol.51 , pp. 218-223
    • Kwon-Chung, K.J.1    Rhodes, J.C.2
  • 67
    • 0038705053 scopus 로고    scopus 로고
    • Regulation of cytochrome C oxidase subunit 1 (COX1) expression in Cryptococcus neoformans by temperature and host environment
    • D.L. Toffaletti, M. Del Poeta, T.H. Rude, F.S. Dietrich, and J.R. Perfect Regulation of cytochrome C oxidase subunit 1 (COX1) expression in Cryptococcus neoformans by temperature and host environment Microbiology 149 2003 1041 1049
    • (2003) Microbiology , vol.149 , pp. 1041-1049
    • Toffaletti, D.L.1    Del Poeta, M.2    Rude, T.H.3    Dietrich, F.S.4    Perfect, J.R.5
  • 69
    • 0037378930 scopus 로고    scopus 로고
    • Cryptococcus neoformans with a mutation in the tetra tricopeptide repeat-containing gene, CCN1, causes subcutaneous lesions but fails to cause systemic infection
    • S. Chung, P. Mondon, Y.C. Chang, and K.J. Kwon-Chung Cryptococcus neoformans with a mutation in the tetra tricopeptide repeat-containing gene, CCN1, causes subcutaneous lesions but fails to cause systemic infection Infect. Immun. 71 2003 1988 1994
    • (2003) Infect. Immun. , vol.71 , pp. 1988-1994
    • Chung, S.1    Mondon, P.2    Chang, Y.C.3    Kwon-Chung, K.J.4
  • 70
    • 0034052527 scopus 로고    scopus 로고
    • RAS1 regulates filamentation, mating, and growth at high temperature of Cryptococcus neoformans
    • J.A. Alspaugh, L.M. Cavallo, J.R. Perfect, and J. Heitman RAS1 regulates filamentation, mating, and growth at high temperature of Cryptococcus neoformans Mol. Microbiol. 36 2000 352 365
    • (2000) Mol. Microbiol. , vol.36 , pp. 352-365
    • Alspaugh, J.A.1    Cavallo, L.M.2    Perfect, J.R.3    Heitman, J.4
  • 71
    • 0142153855 scopus 로고    scopus 로고
    • The phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans
    • D.S. Fox, G.M. Cox, and J. Heitman The phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans Eukaryot. Cell 2 2003 1025 1035
    • (2003) Eukaryot. Cell , vol.2 , pp. 1025-1035
    • Fox, D.S.1    Cox, G.M.2    Heitman, J.3
  • 72
    • 0038460048 scopus 로고    scopus 로고
    • The Cryptococcus neoformans MAP kinase homolog Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function
    • P.R. Kraus, D.S. Fox, G.M. Cox, and J. Heitman The Cryptococcus neoformans MAP kinase homolog Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function Mol. Microbiol. 48 2003 1377 1387
    • (2003) Mol. Microbiol. , vol.48 , pp. 1377-1387
    • Kraus, P.R.1    Fox, D.S.2    Cox, G.M.3    Heitman, J.4
  • 73
    • 2942595896 scopus 로고    scopus 로고
    • Cryptococcus neoformans Ilv2p confers resistance to sulfometuron methyl and is required for survival at 37C and for virulence and survival in vivo
    • J.M. Kingsbury, G.M. Cox, and J.H. McCusker Cryptococcus neoformans Ilv2p confers resistance to sulfometuron methyl and is required for survival at 37C and for virulence and survival in vivo Microbiology 150 2004 1547 1558
    • (2004) Microbiology , vol.150 , pp. 1547-1558
    • Kingsbury, J.M.1    Cox, G.M.2    McCusker, J.H.3
  • 74
    • 2942635960 scopus 로고    scopus 로고
    • A Novel Chimeric SPE3-LYS9 gene in the human pathogen Cryptococcus neoformans
    • J.M. Kingsbury, Z. Yang, T.M. Ganous, G.M. Cox, and J.H. McCusker A Novel Chimeric SPE3-LYS9 gene in the human pathogen Cryptococcus neoformans Eukaryot. Cell 3 2004 752 763
    • (2004) Eukaryot. Cell , vol.3 , pp. 752-763
    • Kingsbury, J.M.1    Yang, Z.2    Ganous, T.M.3    Cox, G.M.4    McCusker, J.H.5
  • 76
    • 0034959767 scopus 로고    scopus 로고
    • Two cyclophilin a homologs with shared and distinct functions are expressed in Cryptococcus neoformans
    • P. Wang, M.E. Cardenas, G.M. Cox, J.R. Perfect, and J. Heitman Two cyclophilin A homologs with shared and distinct functions are expressed in Cryptococcus neoformans EMBO Rep. 21 2001 511 518
    • (2001) EMBO Rep. , vol.21 , pp. 511-518
    • Wang, P.1    Cardenas, M.E.2    Cox, G.M.3    Perfect, J.R.4    Heitman, J.5
  • 79
    • 0029988469 scopus 로고    scopus 로고
    • Stress tolerance and pathogenic potential of a mannitol-mutant of Cryptococcus neoformans
    • V.P. Chaturvedi, T. Flynn, W.G. Niehaus, and B. Wong Stress tolerance and pathogenic potential of a mannitol-mutant of Cryptococcus neoformans Microbiology 142 1996 937 943
    • (1996) Microbiology , vol.142 , pp. 937-943
    • Chaturvedi, V.P.1    Flynn, T.2    Niehaus, W.G.3    Wong, B.4
  • 81
    • 24344448974 scopus 로고    scopus 로고
    • The role of Mn superoxide dismutase (SOD2) in Cryptococcus neoformans serotype A antioxidant defense and virulence
    • abstract: F-073
    • Giles, S., Perfect, J.R. and Cox, G.M. (2004) The role of Mn superoxide dismutase (SOD2) in Cryptococcus neoformans serotype A antioxidant defense and virulence. 104th Am. Soc. Microbiol., abstract: F-073.
    • (2004) 104th Am. Soc. Microbiol.
    • Giles, S.1    Perfect, J.R.2    Cox, G.M.3
  • 82
    • 1542511805 scopus 로고    scopus 로고
    • Thiol peroxidase is critical for virulence and resistance to nitric oxide and peroxide in the fungal pathogen, Cryptococcus neoformans
    • T.A. Missall, M.E. Pusateri, and J.K. Lodge Thiol peroxidase is critical for virulence and resistance to nitric oxide and peroxide in the fungal pathogen, Cryptococcus neoformans Mol. Microbiol. 51 2004 1447 1448
    • (2004) Mol. Microbiol. , vol.51 , pp. 1447-1448
    • Missall, T.A.1    Pusateri, M.E.2    Lodge, J.K.3
  • 84
    • 0026702519 scopus 로고
    • Cryptococcal immunity and immunostimulation
    • J.W. Murphy Cryptococcal immunity and immunostimulation Adv. Exp. Med. Biol. 319 1992 225 230
    • (1992) Adv. Exp. Med. Biol. , vol.319 , pp. 225-230
    • Murphy, J.W.1
  • 85
    • 85047696699 scopus 로고
    • Overview of host defenses in fungal infections
    • S.M. Levitz Overview of host defenses in fungal infections Clin. Infect. Dis. 14 1 1992 S37 S42
    • (1992) Clin. Infect. Dis. , vol.14 , Issue.1
    • Levitz, S.M.1
  • 86
    • 0028938945 scopus 로고
    • Role of tumor necrosis factor and gamma interferon in acquired resistance to Cryptococcus neoformans in the central nervous system of mice
    • K. Aguirre, E.A. Havell, G.W. Gibson, and L.L. Johnson Role of tumor necrosis factor and gamma interferon in acquired resistance to Cryptococcus neoformans in the central nervous system of mice Infect. Immun. 63 1995 1725 1731
    • (1995) Infect. Immun. , vol.63 , pp. 1725-1731
    • Aguirre, K.1    Havell, E.A.2    Gibson, G.W.3    Johnson, L.L.4
  • 87
    • 0029925468 scopus 로고    scopus 로고
    • Contribution of interferon-gamma in protecting mice during pulmonary and disseminated infection with Cryptococcus neoformans
    • K. Kawakami, M. Tohyama, and K. Teruya Contribution of interferon-gamma in protecting mice during pulmonary and disseminated infection with Cryptococcus neoformans FEMS Immunol. Med. Microbiol. 13 1996 133 140
    • (1996) FEMS Immunol. Med. Microbiol. , vol.13 , pp. 133-140
    • Kawakami, K.1    Tohyama, M.2    Teruya, K.3
  • 88
    • 0031184059 scopus 로고    scopus 로고
    • Macrophage inflammatory protein-1 alpha (MIP-alpha) is required for the efferent phase of pulmonary cell-mediated immunity to a Cryptococcus neoformans infection
    • G.B. Huffnagle, R.M. Strieter, and L.K. McNeil Macrophage inflammatory protein-1 alpha (MIP-alpha) is required for the efferent phase of pulmonary cell-mediated immunity to a Cryptococcus neoformans infection J. Immunol. 159 1997 318 327
    • (1997) J. Immunol. , vol.159 , pp. 318-327
    • Huffnagle, G.B.1    Strieter, R.M.2    McNeil, L.K.3
  • 89
    • 0034713712 scopus 로고    scopus 로고
    • Leukocyte recruitment during pulmonary Cryptococcus neoformans infection
    • G.B. Huffnagle, T.R. Traynor, and R.A. McDonald Leukocyte recruitment during pulmonary Cryptococcus neoformans infection Immunopharmacology 48 2000 231 236
    • (2000) Immunopharmacology , vol.48 , pp. 231-236
    • Huffnagle, G.B.1    Traynor, T.R.2    McDonald, R.A.3
  • 90
    • 0026547638 scopus 로고
    • CD4+ T cells cause multinucleated giant cells to form around Cryptococcus neoformans and confine the yeast within the primary site of infection in the respiratory tract
    • J.O. Hill CD4+ T cells cause multinucleated giant cells to form around Cryptococcus neoformans and confine the yeast within the primary site of infection in the respiratory tract J. Exp. Med. 175 1992 1685 1695
    • (1992) J. Exp. Med. , vol.175 , pp. 1685-1695
    • Hill, J.O.1
  • 91
    • 0028058588 scopus 로고
    • Macrophage-Cryptococcus interactions
    • (Zwilling, B.S. and Eisenstein, T.K., Eds.), New York, Marcel Dekker, Inc.
    • Levitz, S.M. Macrophage-Cryptococcus interactions. (1994) In: Macrophage-pathogen Interactions (Zwilling, B.S. and Eisenstein, T.K., Eds.), pp.533-43. New York, Marcel Dekker, Inc.
    • (1994) Macrophage-pathogen Interactions , pp. 533-543
    • Levitz, S.M.1
  • 92
    • 0025813354 scopus 로고
    • Predictive value of CD4 lymphocyte numbers for the development of opportunistic infections and malignancies in HIV-infected persons
    • S.M. Crowe, J.B. Carlin, K.I. Stewart, C.R. Lucas, and J.F. Hoy Predictive value of CD4 lymphocyte numbers for the development of opportunistic infections and malignancies in HIV-infected persons J. Acq. Immune Def. Syndr. 4 1991 770 776
    • (1991) J. Acq. Immune Def. Syndr. , vol.4 , pp. 770-776
    • Crowe, S.M.1    Carlin, J.B.2    Stewart, K.I.3    Lucas, C.R.4    Hoy, J.F.5
  • 93
    • 0028866195 scopus 로고
    • Antibody immunity and invasive fungal infections
    • A. Casadevall Antibody immunity and invasive fungal infections Infect. Immun. 63 1995 4211 4218
    • (1995) Infect. Immun. , vol.63 , pp. 4211-4218
    • Casadevall, A.1
  • 94
    • 0026495128 scopus 로고
    • Protective murine monoclonal antibodies to Cryptococcus neoformans
    • J. Mukherjee, M.D. Sharff, and A. Casadevall Protective murine monoclonal antibodies to Cryptococcus neoformans Infect. Immun. 60 1992 4534 4541
    • (1992) Infect. Immun. , vol.60 , pp. 4534-4541
    • Mukherjee, J.1    Sharff, M.D.2    Casadevall, A.3
  • 95
    • 0033788006 scopus 로고    scopus 로고
    • The Cryptocococus neoformans gene DHA1 encodes an antigen that elicits a delayed-type hypersensitivity reaction in immune mice
    • M.A. Mandel, G.G. Grace, K.I. Osborn, F. Schafer, J.W. Murphy, M.J. Orbach, and J.N. Galgiani The Cryptocococus neoformans gene DHA1 encodes an antigen that elicits a delayed-type hypersensitivity reaction in immune mice Infect. Immun. 68 2002 6196 6201
    • (2002) Infect. Immun. , vol.68 , pp. 6196-6201
    • Mandel, M.A.1    Grace, G.G.2    Osborn, K.I.3    Schafer, F.4    Murphy, J.W.5    Orbach, M.J.6    Galgiani, J.N.7
  • 96
    • 0035964321 scopus 로고    scopus 로고
    • Molecular characterization of a mannoprotein with homology to chitin deacetylases that stimulates T-cell responses to Cryptococcus neoformans
    • S.M. Levitz, S. Nong, M.K. Mansour, C. Huang, and C. Specht Molecular characterization of a mannoprotein with homology to chitin deacetylases that stimulates T-cell responses to Cryptococcus neoformans Proc. Natl. Acad. Sci. 98 2001 10422 10427
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 10422-10427
    • Levitz, S.M.1    Nong, S.2    Mansour, M.K.3    Huang, C.4    Specht, C.5
  • 98
    • 24344447535 scopus 로고    scopus 로고
    • Development and characterization of Cryptococcus neoformans strain that produces murine gamma interferon. 1
    • abstract: F-074
    • Wormley, F.L., Cox, G.M. and Perfect, J.R. (2004) Development and characterization of Cryptococcus neoformans strain that produces murine gamma interferon. 1, 104th Am. Soc. Microbiol., abstract: F-074.
    • (2004) 104th Am. Soc. Microbiol.
    • Wormley, F.L.1    Cox, G.M.2    Perfect, J.R.3
  • 99
    • 1342344911 scopus 로고    scopus 로고
    • CNLAC1 is required for extrapulmonary dissemination of Cryptococcus neoformans but not pulmonary persistence
    • M.C. Noverr, P.R. Williamson, R.S. Fajardo, and G.B. Huffnagle CNLAC1 is required for extrapulmonary dissemination of Cryptococcus neoformans but not pulmonary persistence Infect. Immun. 72 3 2004 1693 1699
    • (2004) Infect. Immun. , vol.72 , Issue.3 , pp. 1693-1699
    • Noverr, M.C.1    Williamson, P.R.2    Fajardo, R.S.3    Huffnagle, G.B.4
  • 100
    • 0042195922 scopus 로고    scopus 로고
    • A Phenotypic switching of Cryptococcus neoformans can influence the outcome of the human immune response
    • D. Pietrella, B. Fries, P. Cupo, F. Bistoni, A. Casadevall, and A. Vecchiarelli A Phenotypic switching of Cryptococcus neoformans can influence the outcome of the human immune response Microbiology 5 2003 513 522
    • (2003) Microbiology , vol.5 , pp. 513-522
    • Pietrella, D.1    Fries, B.2    Cupo, P.3    Bistoni, F.4    Casadevall, A.5    Vecchiarelli, A.6
  • 102
    • 0037373354 scopus 로고    scopus 로고
    • Role of PLB1 in pulmonary inflammation and cryptococcal eicosanoid production
    • M.C. Noverr, G.M. Cox, J.R. Perfect, and G.B. Huffnagle Role of PLB1 in pulmonary inflammation and cryptococcal eicosanoid production Infect. Immun. 71 2003 1538 1547
    • (2003) Infect. Immun. , vol.71 , pp. 1538-1547
    • Noverr, M.C.1    Cox, G.M.2    Perfect, J.R.3    Huffnagle, G.B.4
  • 103
    • 1942533402 scopus 로고    scopus 로고
    • Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion
    • M.A. Olszewski, M.C. Noverr, G.H. Chen, G.B. Toews, G.M. Cox, J.R. Perfect, and G.B. Huffnagle Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion Am J. Pathol. 164 5 2004 1761 1771
    • (2004) Am J. Pathol. , vol.164 , Issue.5 , pp. 1761-1771
    • Olszewski, M.A.1    Noverr, M.C.2    Chen, G.H.3    Toews, G.B.4    Cox, G.M.5    Perfect, J.R.6    Huffnagle, G.B.7
  • 104
    • 0035909926 scopus 로고    scopus 로고
    • Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages
    • J.N. Steenbergen, H.A. Shuman, and A. Casadevall Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages Proc. Natl. Acad. Sci. 98 2001 15245 15250
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 15245-15250
    • Steenbergen, J.N.1    Shuman, H.A.2    Casadevall, A.3
  • 105
    • 0041823555 scopus 로고    scopus 로고
    • Cryptococcus neoformans is enhanced after growth in the genetically malleable enhanced after growth in the genetically malleable host, Dictyostelium discoideum
    • J.N. Steenbergen, H.A. Shuman, and A. Casadevall Cryptococcus neoformans is enhanced after growth in the genetically malleable enhanced after growth in the genetically malleable host, Dictyostelium discoideum Infect. Immun. 2003 4862 4872
    • (2003) Infect. Immun. , pp. 4862-4872
    • Steenbergen, J.N.1    Shuman, H.A.2    Casadevall, A.3
  • 106
    • 3342963000 scopus 로고    scopus 로고
    • Challenge of Drosophila melanogaster with Cryptococcus neoformans and Role of the Innate Immune Response
    • Y. Apidianakis, L.G. Rhame, J. Heitman, F.M. Ausubel, S.B. Calderwood, and E. Mylonakis Challenge of Drosophila melanogaster with Cryptococcus neoformans and Role of the Innate Immune Response Eukaryot. Cell 3 2 2004 413 419
    • (2004) Eukaryot. Cell , vol.3 , Issue.2 , pp. 413-419
    • Apidianakis, Y.1    Rhame, L.G.2    Heitman, J.3    Ausubel, F.M.4    Calderwood, S.B.5    Mylonakis, E.6
  • 107
    • 0037180512 scopus 로고    scopus 로고
    • Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis
    • E. Mylonakis, F.M. Ausubel, J.R. Perfect, J. Heitman, and S.B. Calderwood Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis Proc. Natl. Acad. Sci. 99 2002 15675 15680
    • (2002) Proc. Natl. Acad. Sci. , vol.99 , pp. 15675-15680
    • Mylonakis, E.1    Ausubel, F.M.2    Perfect, J.R.3    Heitman, J.4    Calderwood, S.B.5
  • 109
    • 0028952697 scopus 로고
    • Variation in the structure of glucuronoxylomannan epitope that elicits protective antibodies
    • R.L. Cherniak, L.C. Morris, T. Belay, E.D. Spitzer, and A. Casadevall Variation in the structure of glucuronoxylomannan epitope that elicits protective antibodies Infect. Immun. 63 1995 1899 1905
    • (1995) Infect. Immun. , vol.63 , pp. 1899-1905
    • Cherniak, R.L.1    Morris, L.C.2    Belay, T.3    Spitzer, E.D.4    Casadevall, A.5
  • 111
    • 0029933813 scopus 로고    scopus 로고
    • Fungal virulence genes as targets for antifungal chemotherapy
    • J.R. Perfect Fungal virulence genes as targets for antifungal chemotherapy Chemotherapy 40 1996 1577 1583
    • (1996) Chemotherapy , vol.40 , pp. 1577-1583
    • Perfect, J.R.1
  • 112
    • 0027372019 scopus 로고
    • The gene encoding for phosphoaminoimidazole carboxylase is essential for growth of Cryptococcus neoformans in cerebrospinal fluid
    • J.R. Perfect, D.L. Toffaletti, and T.H. Rude The gene encoding for phosphoaminoimidazole carboxylase is essential for growth of Cryptococcus neoformans in cerebrospinal fluid Infect. Immun. 61 1993 4446 4451
    • (1993) Infect. Immun. , vol.61 , pp. 4446-4451
    • Perfect, J.R.1    Toffaletti, D.L.2    Rude, T.H.3
  • 113
    • 0343192437 scopus 로고    scopus 로고
    • Identification and characterization of a highly conserved calcineurin binding protein CBP1/calcipressin in Cryptococcus neoformans
    • J. Gorlach, D.S. Fox, N.S. Cutler, G.M. Cox, J.R. Perfect, and J. Heitman Identification and characterization of a highly conserved calcineurin binding protein CBP1/calcipressin in Cryptococcus neoformans EMBO J. 19 2000 3618 3629
    • (2000) EMBO J. , vol.19 , pp. 3618-3629
    • Gorlach, J.1    Fox, D.S.2    Cutler, N.S.3    Cox, G.M.4    Perfect, J.R.5    Heitman, J.6
  • 114
    • 4844231595 scopus 로고    scopus 로고
    • Cryptococcus neoformans methionine synthase: Expression analysis and requirement for virulence
    • R.C. Pascon, T.M. Ganous, J.M. Kingsbury, G.M. Cox, and J.H. McCusker Cryptococcus neoformans methionine synthase: expression analysis and requirement for virulence Microbiology 150 2004 3013 3023
    • (2004) Microbiology , vol.150 , pp. 3013-3023
    • Pascon, R.C.1    Ganous, T.M.2    Kingsbury, J.M.3    Cox, G.M.4    McCusker, J.H.5
  • 115
    • 0035008701 scopus 로고    scopus 로고
    • Identification and characterization of the Cryptococcus neoformans phosphomannose isomerase-encoding gene, MAN1, and its impact on pathogenicity
    • E.A. Wills, I.S. Roberts, M. Del Poeta, J. Rivera, A. Casadevall, G.M. Cox, and J.R. Perfect Identification and characterization of the Cryptococcus neoformans phosphomannose isomerase-encoding gene, MAN1, and its impact on pathogenicity Mol. Microbiol. 40 3 2001 610 620
    • (2001) Mol. Microbiol. , vol.40 , Issue.3 , pp. 610-620
    • Wills, E.A.1    Roberts, I.S.2    Del Poeta, M.3    Rivera, J.4    Casadevall, A.5    Cox, G.M.6    Perfect, J.R.7
  • 116
    • 0036371632 scopus 로고    scopus 로고
    • Isolation and characterization of capsule structure mutant strains of Cryptococcus neoformans
    • F. Moyrand, B. Klaproth, U. Himmelreich, F. Dromer, and G. Janbon Isolation and characterization of capsule structure mutant strains of Cryptococcus neoformans Mol. Microbiol. 45 3 2002 837 849
    • (2002) Mol. Microbiol. , vol.45 , Issue.3 , pp. 837-849
    • Moyrand, F.1    Klaproth, B.2    Himmelreich, U.3    Dromer, F.4    Janbon, G.5
  • 117
    • 0035114113 scopus 로고    scopus 로고
    • Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformans
    • D.S. Fox, M.C. Cruz, R.A. Sia, H. Ke, G.M. Cox, M.E. Cardenas, and J. Heitman Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformans Mol. Microbiol. 39 2001 835 849
    • (2001) Mol. Microbiol. , vol.39 , pp. 835-849
    • Fox, D.S.1    Cruz, M.C.2    Sia, R.A.3    Ke, H.4    Cox, G.M.5    Cardenas, M.E.6    Heitman, J.7
  • 118
    • 0036615226 scopus 로고    scopus 로고
    • Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans
    • W.C. Shen, R.C. Davidson, G.M. Cox, and J. Heitman Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans Eukaryot Cell 1 2002 366 377
    • (2002) Eukaryot Cell , vol.1 , pp. 366-377
    • Shen, W.C.1    Davidson, R.C.2    Cox, G.M.3    Heitman, J.4
  • 119
    • 24344504781 scopus 로고    scopus 로고
    • Cloning and disruption of the Cryptococcus neoformans cytochrome c peroxidase and effects on virulence
    • abstract: F-057
    • Giles, S.S. and Cox, G.M. (2003) Cloning and disruption of the Cryptococcus neoformans cytochrome c peroxidase and effects on virulence. 103rd Am. Soc. Microbiol., abstract: F-057.
    • (2003) 103rd Am. Soc. Microbiol.
    • Giles, S.S.1    Cox, G.M.2
  • 120
    • 0035047590 scopus 로고    scopus 로고
    • CAMP dependent protein kinase controls virulence of the fungal pathogen, Cryptococcus neoformans
    • C. D'Souza, J.A. Alspaugh, C. Yue, M. Cox Gary, R. Perfect John, and J. Heitman CAMP dependent protein kinase controls virulence of the fungal pathogen, Cryptococcus neoformans Mol. Cell Biol. 21 2001 3179 3191
    • (2001) Mol. Cell Biol. , vol.21 , pp. 3179-3191
    • D'Souza, C.1    Alspaugh, J.A.2    Yue, C.3    Cox Gary, M.4    Perfect John, R.5    Heitman, J.6
  • 121
    • 2542587112 scopus 로고    scopus 로고
    • The alpha-specific cell identity factor Sxi1alpha is not required for virulence of Cryptococcus neoformans
    • C.M. Hull, G.M. Cox, and J. Heitman The alpha-specific cell identity factor Sxi1alpha is not required for virulence of Cryptococcus neoformans Infect. Immun. 72 6 2004 3643 3645
    • (2004) Infect. Immun. , vol.72 , Issue.6 , pp. 3643-3645
    • Hull, C.M.1    Cox, G.M.2    Heitman, J.3
  • 122
    • 0345268706 scopus 로고    scopus 로고
    • Characterization of Cu, Zn superoxide dismutase (SOD1) gene knock-out mutant of Cryptococcus neoformans var. gattii: Role in biology and virulence
    • S.D. Narasipura, J.G. Ault, M.J. Behr, V. Chaturvedi, and S. Chaturvedi Characterization of Cu, Zn superoxide dismutase (SOD1) gene knock-out mutant of Cryptococcus neoformans var. gattii: role in biology and virulence Mol. Microbiol. 47 2003 1681 1694
    • (2003) Mol. Microbiol. , vol.47 , pp. 1681-1694
    • Narasipura, S.D.1    Ault, J.G.2    Behr, M.J.3    Chaturvedi, V.4    Chaturvedi, S.5
  • 124
    • 0142153855 scopus 로고    scopus 로고
    • Phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans
    • D.S. Fox, G.M. Cox, and J. Heitman Phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans Eukaryot. Cell 2 2003 1025 1035
    • (2003) Eukaryot. Cell , vol.2 , pp. 1025-1035
    • Fox, D.S.1    Cox, G.M.2    Heitman, J.3
  • 125
    • 0042825487 scopus 로고    scopus 로고
    • Importance of a developmentally regulated pheromone receptor of Cryptococcus neoformans for virulence
    • Y.C. Chang, G.F. Miller, and K.J. Kwon-Chung Importance of a developmentally regulated pheromone receptor of Cryptococcus neoformans for virulence Infect. Immun. 71 9 2003 4953 4960
    • (2003) Infect. Immun. , vol.71 , Issue.9 , pp. 4953-4960
    • Chang, Y.C.1    Miller, G.F.2    Kwon-Chung, K.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.