메뉴 건너뛰기




Volumn 3, Issue 2, 2004, Pages 420-429

Cryptococcus neoformans virulence gene discovery through insertional mutagenesis

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; BACTERIAL DNA; CHLORIDE CHANNEL; CLC 1 CHANNEL; CLC 2 CHLORIDE CHANNELS; CLC-1 CHANNEL; CLC-2 CHLORIDE CHANNELS; LACCASE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; NOURSEOTHRICIN ACETYLTRANSFERASE; STREPTOTHRICIN; T DNA; T-DNA; VIRULENCE FACTOR;

EID: 4143077083     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.3.2.420-429.2004     Document Type: Article
Times cited : (155)

References (53)
  • 2
    • 0038257276 scopus 로고
    • The classification of herbicides and types of toxicity
    • L. J. Audus (ed.), Academic Press, London, United Kingdom
    • Brian, R. C. 1964. The classification of herbicides and types of toxicity, p. 1-37. In L. J. Audus (ed.), The physiology and biochemistry of herbicides. Academic Press, London, United Kingdom.
    • (1964) The Physiology and Biochemistry of Herbicides , pp. 1-37
    • Brian, R.C.1
  • 3
    • 0033920913 scopus 로고    scopus 로고
    • Signature-tagged and directed mutagenesis identify PABA synthetase as essential for Aspergillus fumigatus pathogenicity
    • Brown, J. S., A. Aufauvre-Brown, J. Brown, J. M. Jennings, H. Arst, Jr., and D. W. Holden. 2000. Signature-tagged and directed mutagenesis identify PABA synthetase as essential for Aspergillus fumigatus pathogenicity. Mol. Microbiol. 36:1371-1380.
    • (2000) Mol. Microbiol. , vol.36 , pp. 1371-1380
    • Brown, J.S.1    Aufauvre-Brown, A.2    Brown, J.3    Jennings, J.M.4    Arst Jr., H.5    Holden, D.W.6
  • 4
    • 0029066831 scopus 로고
    • Trans-kingdom T-DNA transfer from Agrobacterium tumefaciens to Saccharomyces cerevisiae
    • Bundock, P., A. den Dulk-Ras, A. Beijersbergen, and P. J. J. Hooykaas. 1995. Trans-kingdom T-DNA transfer from Agrobacterium tumefaciens to Saccharomyces cerevisiae. EMBO J. 14:3206-3214.
    • (1995) EMBO J. , vol.14 , pp. 3206-3214
    • Bundock, P.1    Den Dulk-Ras, A.2    Beijersbergen, A.3    Hooykaas, P.J.J.4
  • 5
    • 0030446310 scopus 로고    scopus 로고
    • Integration of Agrobacterium tumefaciens T-DNA in the Saccharomyces cerevisiae genome by illegitimate recombination
    • Bundock, P., and P. J. J. Hooykaas. 1996. Integration of Agrobacterium tumefaciens T-DNA in the Saccharomyces cerevisiae genome by illegitimate recombination. Proc. Natl. Acad. Sci. USA 93:15272-15275.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 15272-15275
    • Bundock, P.1    Hooykaas, P.J.J.2
  • 6
    • 0036231857 scopus 로고    scopus 로고
    • Insertional mutagenesis in yeasts using T-DNA from Agrobacterium tumefaciens
    • Bundock, P., H. van Attikum, A. den Dulk-Ras, and P. J. J. Hooykaas. 2002. Insertional mutagenesis in yeasts using T-DNA from Agrobacterium tumefaciens. Yeast 19:529-536.
    • (2002) Yeast , vol.19 , pp. 529-536
    • Bundock, P.1    Van Attikum, H.2    Den Dulk-Ras, A.3    Hooykaas, P.J.J.4
  • 8
    • 0033597797 scopus 로고    scopus 로고
    • An adhesin of the yeast pathogen Candida glabrata mediating adherence to human epithelial cells
    • Cormack, B. P., N. Ghori, and S. Falkow. 1999. An adhesin of the yeast pathogen Candida glabrata mediating adherence to human epithelial cells. Science 285:578-582.
    • (1999) Science , vol.285 , pp. 578-582
    • Cormack, B.P.1    Ghori, N.2    Falkow, S.3
  • 9
    • 0035088756 scopus 로고    scopus 로고
    • Agrobacterium tumefaciens-mediated transformation of Fusarium circinatum
    • Covert, S. F., P. Kapoor, M.-H. Lee, A. Briley, and C. J. Nairn. 2001. Agrobacterium tumefaciens-mediated transformation of Fusarium circinatum. Mycol. Res. 105:259-264.
    • (2001) Mycol. Res. , vol.105 , pp. 259-264
    • Covert, S.F.1    Kapoor, P.2    Lee, M.-H.3    Briley, A.4    Nairn, C.J.5
  • 10
    • 0033043180 scopus 로고    scopus 로고
    • Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans
    • Cruz, M. C., L. M. Cavallo, J. M. Görlach, G. Cox, J. R. Perfect, M. E. Cardenas, and J. Heitman. 1999. Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans. Mol. Cell. Biol. 19:4101-4112.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4101-4112
    • Cruz, M.C.1    Cavallo, L.M.2    Görlach, J.M.3    Cox, G.4    Perfect, J.R.5    Cardenas, M.E.6    Heitman, J.7
  • 12
    • 0037487244 scopus 로고    scopus 로고
    • A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans
    • Davidson, R. C., C. B. Nichols, G. M. Cox, J. R. Perfect, and J. Heitman. 2003. A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans. Mol. Microbiol. 49:469-485.
    • (2003) Mol. Microbiol. , vol.49 , pp. 469-485
    • Davidson, R.C.1    Nichols, C.B.2    Cox, G.M.3    Perfect, J.R.4    Heitman, J.5
  • 13
    • 0032506116 scopus 로고    scopus 로고
    • Chloride is an allosteric effector of copper assembly for the yeast multicopper oxidase Fet3p: An unexpected role for intracellular chloride channels
    • Davis-Kaplan, S. R., C. C. Askwith, A. C. Bengtzen, D. Radisky, and J. Kaplan. 1998. Chloride is an allosteric effector of copper assembly for the yeast multicopper oxidase Fet3p: an unexpected role for intracellular chloride channels. Proc. Natl. Acad. Sci. USA 95:13641-13645.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13641-13645
    • Davis-Kaplan, S.R.1    Askwith, C.C.2    Bengtzen, A.C.3    Radisky, D.4    Kaplan, J.5
  • 15
    • 0026653927 scopus 로고
    • Isolation of telomere-like sequences from Cryptococcus neoformans and their use in high-efficiency transformation
    • Edman, J. C. 1992. Isolation of telomere-like sequences from Cryptococcus neoformans and their use in high-efficiency transformation. Mol. Cell. Biol. 12:2777-2783.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2777-2783
    • Edman, J.C.1
  • 17
    • 0142216112 scopus 로고    scopus 로고
    • Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: Implications for an outbreak on Vancouver Island, Canada
    • Fraser, J. A., R. L. Subaran, C. B. Nichols, and J. Heitman. 2003. Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, Canada. Eukaryot. Cell 2:1036-1045.
    • (2003) Eukaryot. Cell , vol.2 , pp. 1036-1045
    • Fraser, J.A.1    Subaran, R.L.2    Nichols, C.B.3    Heitman, J.4
  • 18
    • 0036851036 scopus 로고    scopus 로고
    • Phenotypic switching in Cryptococcus neoformans
    • Fries, B. C., D. L. Goldman, and A. Casadevall. 2002. Phenotypic switching in Cryptococcus neoformans. Microbes Infect. 4:1345-1352.
    • (2002) Microbes Infect. , vol.4 , pp. 1345-1352
    • Fries, B.C.1    Goldman, D.L.2    Casadevall, A.3
  • 21
    • 0034929551 scopus 로고    scopus 로고
    • The diversity of retrotransposons in the yeast Cryptococcus neoformans
    • Goodwin, T. J., and R. T. M. Poulter. 2001. The diversity of retrotransposons in the yeast Cryptococcus neoformans. Yeast 18:865-880.
    • (2001) Yeast , vol.18 , pp. 865-880
    • Goodwin, T.J.1    Poulter, R.T.M.2
  • 22
    • 0027136757 scopus 로고
    • The GEF1 gene of Saccharomyces cerevisiae encodes an integral membrane protein, mutations in which have effects on respiration and iron-limited growth
    • Greene, J. R., N. H. Brown, B. J. DiDomenico, J. Kaplan, and D. J. Eide. 1993. The GEF1 gene of Saccharomyces cerevisiae encodes an integral membrane protein, mutations in which have effects on respiration and iron-limited growth. Mol. Gen. Genet. 241:542-553.
    • (1993) Mol. Gen. Genet. , vol.241 , pp. 542-553
    • Greene, J.R.1    Brown, N.H.2    DiDomenico, B.J.3    Kaplan, J.4    Eide, D.J.5
  • 23
    • 0032586277 scopus 로고    scopus 로고
    • On the origins of congenic MATα and MATa strains of the pathogenic yeast Cryptococcus neoformans
    • Heitman, J., B. Allen, J. A. Alspaugh, and K. J. Kwon-Chung. 1999. On the origins of congenic MATα and MATa strains of the pathogenic yeast Cryptococcus neoformans. Fungal Genet. Biol. 28:1-5.
    • (1999) Fungal Genet. Biol. , vol.28 , pp. 1-5
    • Heitman, J.1    Allen, B.2    Alspaugh, J.A.3    Kwon-Chung, K.J.4
  • 24
    • 0036948447 scopus 로고    scopus 로고
    • Genetics of Cryptococcus neoformans
    • Hull, C. M., and J. Heitman. 2002. Genetics of Cryptococcus neoformans. Annu. Rev. Genet. 36:557-615.
    • (2002) Annu. Rev. Genet. , vol.36 , pp. 557-615
    • Hull, C.M.1    Heitman, J.2
  • 25
    • 0034833109 scopus 로고    scopus 로고
    • Pathogenicity genes of phytopathogenic fungi
    • Idnurm, A., and B. J. Howlett 2001. Pathogenicity genes of phytopathogenic fungi. Mol. Plant Pathol. 2:241-255.
    • (2001) Mol. Plant Pathol. , vol.2 , pp. 241-255
    • Idnurm, A.1    Howlett, B.J.2
  • 26
    • 0037256142 scopus 로고    scopus 로고
    • Molecular and genetic characterization of a serotype A MATa Cryptococcus neoformans isolate
    • Keller, S. M., M. A. Viviani, M. C. Esposto, M. Cogliati, and B. L. Wickes. 2003. Molecular and genetic characterization of a serotype A MATa Cryptococcus neoformans isolate. Microbiology 149:131-142.
    • (2003) Microbiology , vol.149 , pp. 131-142
    • Keller, S.M.1    Viviani, M.A.2    Esposto, M.C.3    Cogliati, M.4    Wickes, B.L.5
  • 27
    • 0038460048 scopus 로고    scopus 로고
    • The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function
    • Kraus, P. R., D. S. Fox, G. M. Cox, and J. Heitman. 2003. The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function. Mol. Microbiol. 48:1377-1387.
    • (2003) Mol. Microbiol. , vol.48 , pp. 1377-1387
    • Kraus, P.R.1    Fox, D.S.2    Cox, G.M.3    Heitman, J.4
  • 29
    • 0026334016 scopus 로고
    • Genetic association of mating types and virulence in Cryptococcus neoformans
    • Kwon-Chung, K. J., J. C. Edman, and B. L. Wickes. 1992. Genetic association of mating types and virulence in Cryptococcus neoformans. Infect. Immun. 60:602-605.
    • (1992) Infect. Immun. , vol.60 , pp. 602-605
    • Kwon-Chung, K.J.1    Edman, J.C.2    Wickes, B.L.3
  • 30
    • 0034687743 scopus 로고    scopus 로고
    • Identification of the MATa mating-type locus of Cryptococcus neoformans reveals a serotype A MATa strain thought to have been extinct
    • Lengeler, K. B., P. Wang, G. M. Cox, J. R. Perfect, and J. Heitman. 2000. Identification of the MATa mating-type locus of Cryptococcus neoformans reveals a serotype A MATa strain thought to have been extinct. Proc. Natl. Acad. Sci. USA 97:14455-14460.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 14455-14460
    • Lengeler, K.B.1    Wang, P.2    Cox, G.M.3    Perfect, J.R.4    Heitman, J.5
  • 32
    • 0035119757 scopus 로고    scopus 로고
    • A new dominant selectable marker for use in Cryptococcus neoformans
    • McDade, H. C., and G. M. Cox. 2001. A new dominant selectable marker for use in Cryptococcus neoformans. Med. Mycol. 39:151-154.
    • (2001) Med. Mycol. , vol.39 , pp. 151-154
    • McDade, H.C.1    Cox, G.M.2
  • 33
    • 0041322875 scopus 로고    scopus 로고
    • Updated view of Cryptococcus neoformans mating type and virulence
    • Mitchell, A. P. 2003. Updated view of Cryptococcus neoformans mating type and virulence. Infect. Immun. 71:4829-4830.
    • (2003) Infect. Immun. , vol.71 , pp. 4829-4830
    • Mitchell, A.P.1
  • 34
  • 35
    • 0342614926 scopus 로고    scopus 로고
    • Codon usage tabulated from international DNA sequence databases: Status for the year 2000
    • Nakamura, Y., T. Gojobori, and T. Ikemura. 2000. Codon usage tabulated from international DNA sequence databases: status for the year 2000. Nucleic Acids Res. 28:292.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 292
    • Nakamura, Y.1    Gojobori, T.2    Ikemura, T.3
  • 36
    • 0035102985 scopus 로고    scopus 로고
    • Identification of virulence mutants of the fungal pathogen Cryptococcus neoformans using signature-tagged mutagenesis
    • Nelson, R. T., J. Hua, B. Pryor, and J. K. Lodge. 2001. Identification of virulence mutants of the fungal pathogen Cryptococcus neoformans using signature-tagged mutagenesis. Genetics 157:935-947.
    • (2001) Genetics , vol.157 , pp. 935-947
    • Nelson, R.T.1    Hua, J.2    Pryor, B.3    Lodge, J.K.4
  • 37
    • 0041971075 scopus 로고    scopus 로고
    • Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and α isolates
    • Nielsen, K., G. M. Cox, P. Wang, D. L. Toffaletti, J. R. Perfect, and J. Heitman. 2003. Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and α isolates. Infect. Immun. 71:4831-4841.
    • (2003) Infect. Immun. , vol.71 , pp. 4831-4841
    • Nielsen, K.1    Cox, G.M.2    Wang, P.3    Toffaletti, D.L.4    Perfect, J.R.5    Heitman, J.6
  • 38
    • 0036460071 scopus 로고    scopus 로고
    • clap1, a gene encoding a copper-transporting ATPase involved in the process of infection by the phytopathogenic fungus Colletotrichum lindemuthianum
    • Parisot, D., M. Dufresne, C. Veneault, R. Laugé, and T. Langin. 2002. clap1, a gene encoding a copper-transporting ATPase involved in the process of infection by the phytopathogenic fungus Colletotrichum lindemuthianum. Mol. Genet. Genomics 268:139-151.
    • (2002) Mol. Genet. Genomics , vol.268 , pp. 139-151
    • Parisot, D.1    Dufresne, M.2    Veneault, C.3    Laugé, R.4    Langin, T.5
  • 40
    • 0029931717 scopus 로고    scopus 로고
    • A putative cyclic peptide efflux pump encoded by the TOXA gene of the plant-pathogenic fungus Cochliobolus carbonum
    • Pitkin, J. W., D. G. Panaccione, and J. D. Walton. 1996. A putative cyclic peptide efflux pump encoded by the TOXA gene of the plant-pathogenic fungus Cochliobolus carbonum. Microbiology 142:1557-1565.
    • (1996) Microbiology , vol.142 , pp. 1557-1565
    • Pitkin, J.W.1    Panaccione, D.G.2    Walton, J.D.3
  • 42
    • 0038054472 scopus 로고    scopus 로고
    • The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans
    • Steenbergen, J. N., and A. Casadevall. 2003. The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans. Microbes Infect. 5:667-675.
    • (2003) Microbes Infect. , vol.5 , pp. 667-675
    • Steenbergen, J.N.1    Casadevall, A.2
  • 43
    • 0041823555 scopus 로고    scopus 로고
    • Cryptococcus neoformans virulence is enhanced after growth in the genetically malleable host Dictyostelium discoideum
    • Steenbergen, J. N., J. D. Nosanchuk, S. D. Malliaris, and A. Casadevall. 2003. Cryptococcus neoformans virulence is enhanced after growth in the genetically malleable host Dictyostelium discoideum. Infect. Immun. 71:4862-4872.
    • (2003) Infect. Immun. , vol.71 , pp. 4862-4872
    • Steenbergen, J.N.1    Nosanchuk, J.D.2    Malliaris, S.D.3    Casadevall, A.4
  • 44
    • 0035909926 scopus 로고    scopus 로고
    • Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages
    • Steenbergen, J. N., H. A. Shuman, and A. Casadevall. 2001. Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages. Proc. Natl. Acad. Sci. USA 98:15245-15250.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 15245-15250
    • Steenbergen, J.N.1    Shuman, H.A.2    Casadevall, A.3
  • 45
    • 0027467293 scopus 로고
    • Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA
    • Toffaletti, D. L., T. H. Rude, S. A. Johnston, D. T. Durack, and J. R. Perfect. 1993. Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA. J. Bacteriol. 175:1405-1411.
    • (1993) J. Bacteriol. , vol.175 , pp. 1405-1411
    • Toffaletti, D.L.1    Rude, T.H.2    Johnston, S.A.3    Durack, D.T.4    Perfect, J.R.5
  • 46
    • 0037507285 scopus 로고    scopus 로고
    • Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C. albicans
    • Uhl, M. A., M. Biery, N. Craig, and A. D. Johnson. 2003. Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C. albicans. EMBO J. 22:2668-2678.
    • (2003) EMBO J. , vol.22 , pp. 2668-2678
    • Uhl, M.A.1    Biery, M.2    Craig, N.3    Johnson, A.D.4
  • 47
    • 0242507584 scopus 로고    scopus 로고
    • Agrobacterium tumefaciens mediated transformation of the oomycete plant pathogen Phytophthora infestans
    • Vijn, I., and F. Govers. 2003. Agrobacterium tumefaciens mediated transformation of the oomycete plant pathogen Phytophthora infestans. Mol. Plant Pathol. 4:459-468.
    • (2003) Mol. Plant Pathol. , vol.4 , pp. 459-468
    • Vijn, I.1    Govers, F.2
  • 48
    • 0035157674 scopus 로고    scopus 로고
    • Isolation of a Cryptococcus neoformans serotype A MATa strain from the Italian environment
    • Viviani, M. A., M. C. Esposto, M. Cogliati, M. T. Montagna, and B. L. Wickes. 2001. Isolation of a Cryptococcus neoformans serotype A MATa strain from the Italian environment. Med. Mycol. 39:383-386.
    • (2001) Med. Mycol. , vol.39 , pp. 383-386
    • Viviani, M.A.1    Esposto, M.C.2    Cogliati, M.3    Montagna, M.T.4    Wickes, B.L.5
  • 49
    • 0028069606 scopus 로고
    • Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: Identification as a laccase
    • Williamson, P. R. 1994. Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: identification as a laccase. J. Bacteriol. 176:656-664.
    • (1994) J. Bacteriol. , vol.176 , pp. 656-664
    • Williamson, P.R.1
  • 50
    • 0026651286 scopus 로고
    • Yeast flavohemoglobin is an ancient protein related to globins and a reductase family
    • Zhu, H., and A. F. Riggs. 1992. Yeast flavohemoglobin is an ancient protein related to globins and a reductase family. Proc. Natl. Acad. Sci. USA 89:5015-5019.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5015-5019
    • Zhu, H.1    Riggs, A.F.2
  • 51
    • 0345270456 scopus 로고    scopus 로고
    • Copper-mediated reversal of defective laccase in a Δvph1 avirulent mutant of Cryptococcus neoformans
    • Zhu, X., J. Gibbons, S. Zhang, and P. R. Williamson. 2003. Copper-mediated reversal of defective laccase in a Δvph1 avirulent mutant of Cryptococcus neoformans. Mol. Microbiol. 47:1007-1014.
    • (2003) Mol. Microbiol. , vol.47 , pp. 1007-1014
    • Zhu, X.1    Gibbons, J.2    Zhang, S.3    Williamson, P.R.4
  • 52
    • 0344826573 scopus 로고    scopus 로고
    • A CLC-type chloride channel gene is required for laccase activity and virulence in Cryptococcus neoformans
    • Zhu, X., and P. R. Williamson. 2003. A CLC-type chloride channel gene is required for laccase activity and virulence in Cryptococcus neoformans. Mol. Microbiol. 50:1271-1282.
    • (2003) Mol. Microbiol. , vol.50 , pp. 1271-1282
    • Zhu, X.1    Williamson, P.R.2
  • 53
    • 0033907671 scopus 로고    scopus 로고
    • The transfer of DNA from Agrobacterium tumefaciens into plants: A feast of fundamental insights
    • Zupan, J., T. R. Muth, O. Draper, and P. Zambryski. 2000. The transfer of DNA from Agrobacterium tumefaciens into plants: a feast of fundamental insights. Plant J. 23:11-28.
    • (2000) Plant J. , vol.23 , pp. 11-28
    • Zupan, J.1    Muth, T.R.2    Draper, O.3    Zambryski, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.