Antisense repression in Cryptococcus neoformans as a laboratory tool and potential antifungal strategy

Microbiology

Volumn 148, Issue 1, 2002, Pages 213-219

  Gorlach, Jenifer M ^a   McDade, Henry C ^a   Perfect, John R ^a   Cox, Gary M ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Antisense oligonucleotide; Calcineurin; Fungus; Pathogenesis; Yeast

Indexed keywords

ACTIN; ANTISENSE OLIGONUCLEOTIDE; CALCINEURIN; COMPLEMENTARY DNA; GALACTOSE; LACCASE; MELANIN;

ANTIFUNGAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; FUNGUS GROWTH; GENE CONTROL; GENE FUNCTION; GENE LOCUS; GENE REPRESSION; GENE TARGETING; GENETIC SCREENING; GENETIC TRANSCRIPTION; GENETIC TRANSFORMATION; GROWTH INHIBITION; LABORATORY TEST; MELANOGENESIS; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; SEROTYPE; TEMPERATURE SENSITIVITY; YEAST;

CRYPTOCOCCUS NEOFORMANS; FILOBASIDIELLA NEOFORMANS; FUNGI;

EID: 0036148819     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-148-1-213     Document Type: Article

References (25)

1. Cationic liposome-encapsulated antisense oligonucleotide mediates efficient killing of intracellular Leishmania
2. The actin gene from Cryptococcus neoformans: Structure and phylogenetic analysis
3. Phenocopy of discoidin I-minus mutants by antisense transformation in Dictyostelium
4. On the roles of calcineurin in physiology and virulence in serotype D compared to serotype A strains of Cryptococcus neoformans
5. Gene disruption by biolistic transformation in serotype D strains of Cryptococcus neoformans
6. An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans
7. Isolation of telomerelike sequences from Cryptococcus neoformans and their use in high-efficiency transformation
8. Isolation of the URA5 gene from Cryptococcus neoformans var. neoformans and its use as a selective marker for transformation
9. Antisense RNA: Its functions and applications in gene regulation
10. Antisense RNA: Function and fate of duplex RNA in cells of higher eukaryotes
11. Antisense - Time to shoot the messenger
12. Nuclear antisense RNA
13. Inducible expression of calmodulin antisense RNA in Dictyostelium cells inhibits the completion of cytokinesis
14. Targeted reduction in expression of Trypanosoma cruzi surface glycoprotein gp90 increases parasite infectivity
15. Anti-sense oligonucleotide inhibition of angiotensinogen in the brains of rats and sheep
16. Calcineurin is required for virulence of Cryptococcus neoformans
17. Fungal virulence genes as targets for antifungal chemotherapy
18. Cryptococcus neoformans TRP1 gene by complementation in Saccharomyces cerevisiae
19. Fomivirsen
20. Antisense therapeutics
21. Synthesis of polymerized melanin by Cryptococcus neoformans in rodents
22. Effect of the laccase gene, CNLAC1, on virulence of Cryptococcus neoformans
23. Inhibition of Neurospora crassa growth by a glucan synthase-1 antisense construct
24. The Cryptococcus neoformans GAL7 gene and its use as an inducible promoter