Activation of the steroid and xenobiotic receptor (human pregnane X receptor) by nontaxane microtubule-stabilizing agents

Clinical Cancer Research

Volumn 11, Issue 17, 2005, Pages 6359-6369

  Mani, Sridhar ^a   Huang, Haiyan ^a   Sundarababu, Sumathy ^a   Liu, Wenjing ^a   Kalpana, Ganjam ^a   Smith, Amos B ^b   Horwitz, Susan B ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BACCATIN III; CISPLATIN; CYTOCHROME P450 3A4; DISCODERMOLIDE; DOCETAXEL; DRUG METABOLIZING ENZYME; EPOTHILONE A; EPOTHILONE A DERIVATIVE; EPOTHILONE B; EPOTHILONE B DERIVATIVE; EPOTHILONE DERIVATIVE; GLUTATHIONE TRANSFERASE; IXABEPILONE; LUCIFERASE; MICROTUBULE STABILIZING AGENT; NCOR PROTEIN; PACLITAXEL; PREGNANE X RECEPTOR; PROTEIN; PROTEIN VP15; REPRESSOR PROTEIN; RIFAMPICIN; SMRT PROTEIN; STEROID RECEPTOR; STEROID RECEPTOR COACTIVATOR 1; TRANSCRIPTION FACTOR GAL4; UNCLASSIFIED DRUG; UNINDEXED DRUG; VP15SRC 1 PROTEIN; XENOBIOTIC RECEPTOR;

ARTICLE; BIOASSAY; CANCER CHEMOTHERAPY; CELL STRAIN HEPG2; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG RESISTANCE; ENZYME INDUCTION; GENETIC TRANSCRIPTION; GLUTATHIONE TRANSFERASE PULL DOWN ASSAY; HUMAN; HUMAN CELL; HYBRIDIZATION; IN VITRO STUDY; IN VIVO STUDY; ONE HYBRID SYSTEM; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REPORTER GENE; RIGHTING REFLEX; STEROID AND XENOBIOTIC RECEPTOR PLASMID; TRANSIENT TRANSCRIPTION ASSAY; TWO HYBRID SYSTEM;

ALKANES; ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ARYL HYDROCARBON HYDROXYLASES; BLOTTING, NORTHERN; CARBAMATES; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DNA-BINDING PROTEINS; EPOTHILONES; GLUTATHIONE TRANSFERASE; HISTONE ACETYLTRANSFERASES; HUMANS; IMMUNOBLOTTING; LACTONES; MICE; MICE, INBRED C57BL; NUCLEAR PROTEINS; OXIDOREDUCTASES, N-DEMETHYLATING; PACLITAXEL; PLASMIDS; PYRONES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; REFLEX, ABNORMAL; REPRESSOR PROTEINS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TWO-HYBRID SYSTEM TECHNIQUES; XENOBIOTICS;

EID: 24344454303     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-05-0252     Document Type: Article

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